Mammalian genome : official journal of the International Mammalian Genome Society最新文献_第5页

Correction to: Sequencing and comparative genome analysis of three Indians. 更正:三个印度人的测序和比较基因组分析。

IF 2.5

Mammalian genome : official journal of the International Mammalian Genome Society Pub Date : 2021-10-01 DOI: 10.1007/s00335-021-09886-0

Harish Padh

引用次数: 0

Taxonomic composition and variation in the gut microbiota of laboratory mice. 实验小鼠肠道微生物群的分类组成和变异。

IF 2.5

Mammalian genome : official journal of the International Mammalian Genome Society Pub Date : 2021-08-01 Epub Date: 2021-04-24 DOI: 10.1007/s00335-021-09871-7

Junwon Yang, Jongsik Chun

{"title":"Taxonomic composition and variation in the gut microbiota of laboratory mice.","authors":"Junwon Yang, Jongsik Chun","doi":"10.1007/s00335-021-09871-7","DOIUrl":"https://doi.org/10.1007/s00335-021-09871-7","url":null,"abstract":"The gut microbiota can affect host health, including humans. Mouse models have been used extensively to study the relationships between the host and the gut microbiota. With the development of cost-effective high-throughput DNA sequencing, several methods have been used to identify members of the gut microbiota of laboratory mice. In recent years, the amount of research and knowledge about the mouse gut microbiota has exploded, leading to significant breakthroughs in understanding of the taxonomic composition of and variation in this community. In addition, the rapidly increasing volume of data has allowed the development of public resources for exploring the mouse gut microbiota. In this review, we describe the concepts and pros and cons of basic methodologies that can be used to determine the gut bacterial profile in laboratory mice. We also present the key bacterial components of the mouse gut microbiota from the phylum to the species level and then compare them with those identified in other references. Additionally, we discuss variations in the mouse gut microbiota and their association with experiments using mice. Finally, we summarize the properties and functions of currently available public resources for exploring the mouse gut microbiota.","PeriodicalId":412165,"journal":{"name":"Mammalian genome : official journal of the International Mammalian Genome Society","volume":" ","pages":"297-310"},"PeriodicalIF":2.5,"publicationDate":"2021-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s00335-021-09871-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38903889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

A review on the role of gut microbiota in immune checkpoint blockade therapy for cancer. 肠道微生物群在癌症免疫检查点阻断治疗中的作用综述。

IF 2.5

Mammalian genome : official journal of the International Mammalian Genome Society Pub Date : 2021-08-01 Epub Date: 2021-03-30 DOI: 10.1007/s00335-021-09867-3

Esther Kim, Hyeok Ahn, Hansoo Park

引用次数: 16

Approaching precision medicine by tailoring the microbiota. 通过调整微生物群来实现精准医疗。

IF 2.5

Mammalian genome : official journal of the International Mammalian Genome Society Pub Date : 2021-08-01 Epub Date: 2021-03-01 DOI: 10.1007/s00335-021-09859-3

Gaeun Ryu, Hyojin Kim, Ara Koh

{"title":"Approaching precision medicine by tailoring the microbiota.","authors":"Gaeun Ryu, Hyojin Kim, Ara Koh","doi":"10.1007/s00335-021-09859-3","DOIUrl":"https://doi.org/10.1007/s00335-021-09859-3","url":null,"abstract":"Accumulating evidence has revealed the link between the microbiota and various human diseases. Advances in high-throughput sequencing technologies have identified some consistent disease-associated microbial features, leading to the emerging concept of microbiome-based therapeutics. However, it is also becoming clear that there are considerable variations in the microbiota among patients with the same disease. Variations in the microbial composition and function contribute to substantial differences in metabolic status of the host via production of a myriad of biochemically and functionally different microbial metabolites. Indeed, compelling evidence indicates that individuality of the microbiome may result in individualized responses to microbiome-based therapeutics and other interventions. Mechanistic understanding of the role of the microbiota in diseases and drug metabolism would help us to identify causal relationships and thus guide the development of microbiome-based precision or personalized medicine. In this review, we provide an overview of current efforts to use microbiome-based interventions for the treatment of diseases such as cancer, neurological disorders, and diabetes to approach precision medicine.","PeriodicalId":412165,"journal":{"name":"Mammalian genome : official journal of the International Mammalian Genome Society","volume":" ","pages":"206-222"},"PeriodicalIF":2.5,"publicationDate":"2021-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s00335-021-09859-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25416370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Metagenomics: a path to understanding the gut microbiome. 宏基因组学:了解肠道微生物组的途径。

IF 2.5

Mammalian genome : official journal of the International Mammalian Genome Society Pub Date : 2021-08-01 Epub Date: 2021-07-14 DOI: 10.1007/s00335-021-09889-x

Sandi Yen, Jethro S Johnson

引用次数: 23

Introduction to mammalian genome special issue: the microbiome in human health and disease. 哺乳动物基因组导论特刊:微生物组在人类健康和疾病中的作用。

IF 2.5

Mammalian genome : official journal of the International Mammalian Genome Society Pub Date : 2021-08-01 Epub Date: 2021-06-30 DOI: 10.1007/s00335-021-09888-y

Guillaume Pavlovic, Je Kyung Seong, George M Weinstock

引用次数: 2

New insights into the microbiota of wild mice. 对野生小鼠微生物群的新认识。

IF 2.5

Mammalian genome : official journal of the International Mammalian Genome Society Pub Date : 2021-08-01 Epub Date: 2021-07-09 DOI: 10.1007/s00335-021-09887-z

Ho-Keun Kwon, Je Kyung Seong

引用次数: 3

The human urobiome. 人类泌尿组。

IF 2.5

Mammalian genome : official journal of the International Mammalian Genome Society Pub Date : 2021-08-01 Epub Date: 2021-03-02 DOI: 10.1007/s00335-021-09862-8

L Brubaker, C Putonti, Q Dong, A J Wolfe

{"title":"The human urobiome.","authors":"L Brubaker, C Putonti, Q Dong, A J Wolfe","doi":"10.1007/s00335-021-09862-8","DOIUrl":"https://doi.org/10.1007/s00335-021-09862-8","url":null,"abstract":"Traditionally, the healthy urinary bladder has been considered to be sterile. Several teams have used metagenomic (DNA-dependent) and metaculturomic (culture-dependent) methods to debunk this longstanding dogma. In fact, resident microbial communities (urobiome) have been detected in both adult females and males. Although the field is young, several observations have been made. For example, the urobiome differs between men and women, likely due to anatomical and hormonal differences. Importantly, the urobiome has been associated with a variety of lower urinary tract disorders, including overactive bladder and post-operative urinary tract infection, raising the possibility that clinicians might one day treat symptoms by modifying the urobiome instead of killing the suspected uropathogen. Little is known concerning the relationship between the urobiome and host genetics; so far, only a single paper has reported such a study. However, major efforts have gone into understanding the genomics of the urobiome itself, a process facilitated by the fact that many urobiome studies have used metaculturomic methods to detect and identify microbes. In this narrative review, we will introduce the urobiome with separate sections on the female and male urobiomes, discuss challenges specific to the urobiome, describe newly discovered associations between the urobiome and lower urinary tract symptoms, and highlight the one study that has attempted to relate host genetics and the urobiome. We will finish with a section on how metagenomic surveys and whole genome sequencing of bacterial isolates are improving our understanding of the urobiome and its relationship to lower urinary tract health and disorders.","PeriodicalId":412165,"journal":{"name":"Mammalian genome : official journal of the International Mammalian Genome Society","volume":" ","pages":"232-238"},"PeriodicalIF":2.5,"publicationDate":"2021-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s00335-021-09862-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25421031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10

Enterobacteria and host resistance to infection. 肠杆菌和宿主对感染的抵抗力。

IF 2.5

Mammalian genome : official journal of the International Mammalian Genome Society Pub Date : 2018-08-01 Epub Date: 2018-05-21 DOI: 10.1007/s00335-018-9749-4

Eugene Kang, Alanna Crouse, Lucie Chevallier, Stéphanie M Pontier, Ashwag Alzahrani, Navoun Silué, François-Xavier Campbell-Valois, Xavier Montagutelli, Samantha Gruenheid, Danielle Malo

引用次数: 33

Host genetic regulation of immune-based and infectious diseases : Introduction to mammalian genome special issue: genetics of infectious disease. 宿主免疫和传染病的遗传调控：哺乳动物基因组导论特刊：传染病遗传学。

Mammalian genome : official journal of the International Mammalian Genome Society Pub Date : 2018-08-01 DOI: 10.1007/s00335-018-9779-y

Martin T Ferris, Derek W Hood

引用次数: 0