Aktualnosci Neurologiczne最新文献_第3页

Nerve excitability study – a method to assess the pathophysiology of peripheral nervous system disorders 神经兴奋性研究——一种评估周围神经系统疾病病理生理学的方法

Aktualnosci Neurologiczne Pub Date : 2021-12-31 DOI: 10.15557/an.2021.0026

G. Witkowski, Szymon Owsiak, H. Sienkiewicz-Jarosz

{"title":"Nerve excitability study – a method to assess the pathophysiology of peripheral nervous system disorders","authors":"G. Witkowski, Szymon Owsiak, H. Sienkiewicz-Jarosz","doi":"10.15557/an.2021.0026","DOIUrl":"https://doi.org/10.15557/an.2021.0026","url":null,"abstract":"Nerve excitability study is an interesting extension of classical neurography. The principle of the test is to stimulate the nerve with a long-term depolarising or hyperpolarising stimulus, followed by a test stimulus that induces a complex motor or sensory potential of a given amplitude. The analysis of the intensity of the test stimulus used in chronic depolarisation or hyperpolarisation of the nerve fibre allows for the assessment of changes in nerve excitability. The median nerve is stimulated, and it is possible to assess the excitability of sensory or motor fibres. Nerve excitability study is the only method to evaluate the function of neuronal membrane ion channels in vivo. Test results are impacted by the following membrane-related factors: voltage-gated sodium and potassium ion channels, sodium and potassium ATPase, as well as the degree of fibre myelination and the levels of extracellular and intracellular electrolytes. Nerve excitability study yields a result in the form of a series of complex peripheral nerve excitability parameters, such as the relationship between the stimulus and the excitation threshold, rheobase, fibre chronaxie, threshold electrotonus, and reactivation after action potential. Nerve excitability study helps assess the pathophysiology of nerve fibre damage in various disorders of the peripheral nervous system, such as hereditary polyneuropathies, neurodegenerative or metabolic diseases. The test is highly sensitive, e.g. it shows pre-symptomatic excitability changes. It can also be used to monitor treatment outcomes in metabolic and drug-induced polyneuropathies and to search for peripheral markers of central nervous system channelopathies.","PeriodicalId":41161,"journal":{"name":"Aktualnosci Neurologiczne","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49253346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neurological performance after central nervous system complication of childhood chickenpox 小儿水痘后中枢神经系统并发症的神经功能表现

Aktualnosci Neurologiczne Pub Date : 2021-12-31 DOI: 10.15557/an.2021.0023

J. Frąszczak, A. Mania, P. Kemnitz, Katarzyna Mazur-Melewska, M. Figlerowicz

{"title":"Neurological performance after central nervous system complication of childhood chickenpox","authors":"J. Frąszczak, A. Mania, P. Kemnitz, Katarzyna Mazur-Melewska, M. Figlerowicz","doi":"10.15557/an.2021.0023","DOIUrl":"https://doi.org/10.15557/an.2021.0023","url":null,"abstract":"Varicella-zoster virus is an exclusively human pathogen of an acute exanthematous illness usually linked with childhood. Although the disease is commonly considered benign, varicella-zoster virus bears the potential of causing a wide range of different complications, including central nervous system manifestations. In this paper, an assessment of long-term sequelae and the quality of life in a cohort of patients with neurological complications who survived an acute episode is discussed. We enrolled a total of 71 patients aged two months to 16 years with the diagnosis of varicella complicated by central nervous system disease into the study. Data were collected after their discharge from the hospital by mail and by telephone call interviews using standardised questionnaires. The time from the discharge to the filling of the survey varied between the patients, with a median time of 5.4 years. The collected data were analysed, and the results were compared with the literature. The diagnosis of ischaemic stroke and encephalitis was linked to the most unfavourable outcome, as opposed to acute cerebellar ataxia associated with the most favourable prognosis. Neuropsychological performance should be further monitored to prevent a decrease of independence in everyday performance.","PeriodicalId":41161,"journal":{"name":"Aktualnosci Neurologiczne","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67584068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rare post-vaccination complications: onset of relapsing-remitting multiple sclerosis after COVID-19 vaccination – case reports and literature review 罕见的疫苗接种后并发症:COVID-19疫苗接种后复发缓解型多发性硬化症的发病-病例报告及文献复习

Aktualnosci Neurologiczne Pub Date : 2021-12-31 DOI: 10.15557/an.2021.0029

Joanna Kyc, H. Bartosik-Psujek

引用次数: 0

General movements assessment, part II: the use of general movement assessment as a predictive tool of cerebral palsy – a scoping review 一般运动评估，第二部分:使用一般运动评估作为脑瘫的预测工具-范围审查

Aktualnosci Neurologiczne Pub Date : 2021-12-31 DOI: 10.15557/an.2021.0025

Katarzyna Ostrzyżek-Przeździecka, Jakub Bukowski, Teresa Furman, Natalia Jagielska, Iwona Walecka, Marta Ambroziewicz, Anna Rakowska, J. Gąsior

{"title":"General movements assessment, part II: the use of general movement assessment as a predictive tool of cerebral palsy – a scoping review","authors":"Katarzyna Ostrzyżek-Przeździecka, Jakub Bukowski, Teresa Furman, Natalia Jagielska, Iwona Walecka, Marta Ambroziewicz, Anna Rakowska, J. Gąsior","doi":"10.15557/an.2021.0025","DOIUrl":"https://doi.org/10.15557/an.2021.0025","url":null,"abstract":"The diagnosis of cerebral palsy is usually made between the 12 and 24 months of age which often delays the implementation of early therapeutic intervention. General movements assessment is one of the tools for the early diagnosis of cerebral palsy. The aim of this study was to present the current knowledge on the use of the general movements assessment in predicting cerebral palsy. The literature review was made in accordance with the recommendations of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Statement. The PubMed medical database was searched, 24 publications were identified and included in the detailed analysis. The highest sensitivity was demonstrated for the general movements assessment performed during the fidgety period and in preterm infants. General movements assessment and/or Hammersmith Infant Neurological Examination (HINE) are recommended as a routine screening of newborns with documented risk factors for cerebral for the earliest possible diagnosis. Raising the awareness of medical personnel should be of key importance for the implementation of the recommended procedure.","PeriodicalId":41161,"journal":{"name":"Aktualnosci Neurologiczne","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67584300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The role of neuropsychologist in qualifying patients with movement disorders for deep brain stimulation 神经心理学家对运动障碍患者进行深部脑刺激的作用

Aktualnosci Neurologiczne Pub Date : 2021-12-31 DOI: 10.15557/an.2021.0027

E. Sitek, J. Dulski

{"title":"The role of neuropsychologist in qualifying patients with movement disorders for deep brain stimulation","authors":"E. Sitek, J. Dulski","doi":"10.15557/an.2021.0027","DOIUrl":"https://doi.org/10.15557/an.2021.0027","url":null,"abstract":"The appropriate selection of candidates with movement disorders for deep brain stimulation requires the engagement of a multidisciplinary team, including a movement disorders specialist, neurosurgeon, psychiatrist, neuroradiologist, neurological nurse and a neuropsychologist. The neuropsychological assessment should address not only the cognitive function but also include an interview on the emotional functioning, coping mechanisms, social support, and the adequacy of expectations with regards to deep brain stimulation. Neuropsychiatric interview with the patient and – if possible – his/her proxy, should be supported, but not replaced, by questionnaire assessment. Also, if surgery under local anesthesia is considered, the neuropsychological evaluation can help to establish if the patient is cognitively and emotionally capable of enduring it. In this paper, all the important aspects of neuropsychological evaluation are presented, with special emphasis on dealing with motor limitations during cognitive assessment, conducting the behavioral assessment and addressing the patient’s expectations concerning deep brain stimulation efficacy. Neuropsychiatric evaluation should cover not only the presence and severity of affective symptoms, but also the relationship between motor and emotional state, suicidal ideations, psychosocial stability, and a variety of behavioral problems, including pseudobulbar affect, irritability, and psychotic symptoms. Overall, the comprehensive neuropsychological evaluation for deep brain stimulation candidates extends far beyond cognitive assessment.","PeriodicalId":41161,"journal":{"name":"Aktualnosci Neurologiczne","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67584441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

General movements assessment, part I: Prechtl’s method – the current state of knowledge based on a scoping review 一般运动评估，第一部分:Prechtl的方法-基于范围审查的知识现状

Aktualnosci Neurologiczne Pub Date : 2021-12-31 DOI: 10.15557/an.2021.0024

Anna Rakowska, Sara Tomalak, Katarzyna Ostrzyżek-Przeździecka, J. Gąsior

{"title":"General movements assessment, part I: Prechtl’s method – the current state of knowledge based on a scoping review","authors":"Anna Rakowska, Sara Tomalak, Katarzyna Ostrzyżek-Przeździecka, J. Gąsior","doi":"10.15557/an.2021.0024","DOIUrl":"https://doi.org/10.15557/an.2021.0024","url":null,"abstract":"Advances in pre- and postnatal care have resulted in increased survival rates of infants in risk groups. Consequently, a growing number of children need interdisciplinary care and early intervention in the first stages of life. Early detection of developmental abnormalities may allow for a more effective therapy. Observation of motor and behavioural skills is one of the crucial elements in the assessment of child’s development. Prechtl’s assessment of general movements is used in the first six months of a child’s life. It enables the identification and prediction of neurodevelopmental disorders. The aim of the study was to present Prechtl’s method and summarise knowledge about this approach based on a literature review of PubMed medical database. The key issues related to the assessment procedure, including reliability, consistency and compliance of the method, as well as its use for predicting neurodevelopmental disorders were discussed. Additionally, combined use of the tool with neuroimaging methods for assessing neuromotor development, and knowledge of the use of novel technologies for automatization of the general movements assessment were summarised. Due to its non-invasiveness, availability, and ease of implementation, the method has a wide use in clinical practice. Prechtl’s method allows for a careful observation of the child’s motor skills and may allow both clinicians and parents for early identification of neurodevelopmental disorders.","PeriodicalId":41161,"journal":{"name":"Aktualnosci Neurologiczne","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67584225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Vaccination in multiple sclerosis patients during the COVID-19 pandemic 新冠肺炎大流行期间多发性硬化症患者的疫苗接种

Aktualnosci Neurologiczne Pub Date : 2021-12-20 DOI: 10.15557/an.2021.0018

W. Brola, Ewa Bielecka

{"title":"Vaccination in multiple sclerosis patients during the COVID-19 pandemic","authors":"W. Brola, Ewa Bielecka","doi":"10.15557/an.2021.0018","DOIUrl":"https://doi.org/10.15557/an.2021.0018","url":null,"abstract":"Vaccination is the best strategy for preventing most infectious diseases. Along\u0000 with adhering to the principles of prevention, vaccines are particularly important in\u0000 the time of the COVID-19 pandemic. There is evidence that multiple sclerosis increases\u0000 the risk of developing infections, and the immunosuppressive and immunomodulating\u0000 medications taken by multiple sclerosis patients may increase this risk. No evidence has\u0000 been found that vaccination increases the risk of developing MS or a relapse. It is\u0000 believed that people with multiple sclerosis can be vaccinated safely, and it is a\u0000 mistake not to have a vaccination only because of being diagnosed with multiple\u0000 sclerosis. When determining the indications for vaccination, as well as when selecting\u0000 vaccines and determining the optimal time for their administration, the epidemiological\u0000 situation of the patient’s region of residence and the type of disease-modifying therapy\u0000 should be taken into account. The vaccination-related restrictions mainly apply to\u0000 alemtuzumab, fingolimod, ocrelizumab and cladribine. The article reviews the rules for\u0000 vaccinating multiple sclerosis patients depending on the type of vaccine and the\u0000 disease-modifying therapy used. Recommendations for vaccination against the SARS-CoV-2\u0000 infection in multiple sclerosis patients are also taken into account.","PeriodicalId":41161,"journal":{"name":"Aktualnosci Neurologiczne","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48570554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Treatment of multiple sclerosis during COVID-19 pandemic COVID-19大流行期间多发性硬化症的治疗

Aktualnosci Neurologiczne Pub Date : 2021-12-20 DOI: 10.15557/an.2021.0017

W. Brola, Krystian Kosno, Agnieszka Mitrosz

{"title":"Treatment of multiple sclerosis during COVID-19 pandemic","authors":"W. Brola, Krystian Kosno, Agnieszka Mitrosz","doi":"10.15557/an.2021.0017","DOIUrl":"https://doi.org/10.15557/an.2021.0017","url":null,"abstract":"Multiple sclerosis patients are by definition more susceptible to infections,\u0000 which dependents on the use of disease-modifying treatments. Depending on the mechanism\u0000 of action, individual disease-modifying treatments carry different risks. As a result,\u0000 patients require an individualised approach to initiating and continuing new treatments.\u0000 This problem became very important during the COVID-19 pandemic. In the case of drugs\u0000 with different mechanisms of action on the immune system, the impact of therapy on\u0000 susceptibility to SARS-CoV-2 infections and the course of COVID-19 should be considered.\u0000 Based on the risk/ benefit analysis for the patient, individual therapies have been\u0000 assigned recommendations: 1) low-risk therapies (glatiramer acetate, interferons,\u0000 dimethyl fumarate, teriflunomide) – discontinuation of therapy and delay of treatment\u0000 initiation is not recommended; 2) moderate-risk therapies (fingolimod, natalizumab,\u0000 ocrelizumab, cladribine) – require caution, individual risk/benefit assessment, risk\u0000 analysis of multiple sclerosis symptom exacerbation after drug discontinuation; 3)\u0000 high-risk therapies (alemtuzumab, mitoxantrone, haematopoietic stem cells\u0000 transplantation) – treatment initiation is not recommended, administration of subsequent\u0000 doses requires extreme caution. The article reviews the recommendations and publications\u0000 from the last 2 years, taking into account the changing views on the treatment of\u0000 multiple sclerosis in the time of COVID-19 pandemic.","PeriodicalId":41161,"journal":{"name":"Aktualnosci Neurologiczne","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67583765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Emotional control and illness acceptance in patients with multiple sclerosis – preliminary findings 多发性硬化症患者的情绪控制与疾病接受——初步发现

Aktualnosci Neurologiczne Pub Date : 2021-12-20 DOI: 10.15557/an.2021.0016

Magdalena Obrembska, I. Bednarski, A. Głąbiński

{"title":"Emotional control and illness acceptance in patients with multiple sclerosis –\u0000 preliminary findings","authors":"Magdalena Obrembska, I. Bednarski, A. Głąbiński","doi":"10.15557/an.2021.0016","DOIUrl":"https://doi.org/10.15557/an.2021.0016","url":null,"abstract":"Aim of the study: Mental disorders occur in about 75% of patients with multiple\u0000 sclerosis (MS). Examination of the mental state of patients with multiple sclerosis is\u0000 important for assessing the course of the disease and undertaking appropriate\u0000 therapeutic interventions. The aim of the study was to assess emotional control and\u0000 disease acceptance in multiple sclerosis. Methods: 66 people were qualified for the\u0000 study, including 34 patients with multiple sclerosis and 32 age- and sex-matched\u0000 controls. Emotional control was assessed using the Courtauld Emotional Control Scale\u0000 (CECS), and disease acceptance was evaluated using The Acceptance of Illness Scale\u0000 (AIS). Additionally, a proprietary questionnaire was used to assess auto and allopsychic\u0000 orientation and to collect demographic data. Results: Stronger suppression of depression\u0000 and a lower level of disease acceptance were found in the group of patients with\u0000 multiple sclerosis compared to patients suffering from neurological diseases without\u0000 organic brain damage. Additionally, patients with multiple sclerosis with higher\u0000 education achieved results suggesting a higher level of suppression of emotions and\u0000 suppression of depression than education-matched controls. Patients with multiple\u0000 sclerosis with secondary and higher education scored significantly higher, which means\u0000 worse illness acceptance, than those with primary education. Conclusions: Due to the\u0000 association of emotional suppression with the development of chronic diseases and the\u0000 level of disease acceptance with adaptation to a chronic health condition, it is\u0000 recommended to periodically assess these correlates as part of standard psychological\u0000 examination in patients with multiple sclerosis.","PeriodicalId":41161,"journal":{"name":"Aktualnosci Neurologiczne","volume":"54 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67584052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Takotsubo syndrome in status epilepticus –case report 癫痫持续状态Takotsubo综合征1例报告

Aktualnosci Neurologiczne Pub Date : 2021-12-20 DOI: 10.15557/an.2021.0022

M. Konopko, Maciej Hyla, Szymon Owsiak, H. Sienkiewicz-Jarosz

引用次数: 0