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Association of the Reduced Level of Interleukin-13 in Breast Milk with Chronic Diarrhea in Infancy 母乳中白细胞介素-13水平降低与婴儿慢性腹泻的关系
IF 1.2
Turkish Journal of Immunology Pub Date : 2019-01-01 DOI: 10.25002/tji.2019.1152
S. Moradkhani, M. Mohammadi, Fatemeh Minoochehr, Matin Vesaltalab, Seddighe Amini-Ranjbar, M. Baneshi, F. Seif, M. Khoshmirsafa
{"title":"Association of the Reduced Level of Interleukin-13 in Breast Milk with Chronic Diarrhea in Infancy","authors":"S. Moradkhani, M. Mohammadi, Fatemeh Minoochehr, Matin Vesaltalab, Seddighe Amini-Ranjbar, M. Baneshi, F. Seif, M. Khoshmirsafa","doi":"10.25002/tji.2019.1152","DOIUrl":"https://doi.org/10.25002/tji.2019.1152","url":null,"abstract":"","PeriodicalId":41088,"journal":{"name":"Turkish Journal of Immunology","volume":"31 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74304070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Significant Effect of Conditioned Medium of Umbilical Cord Mesenchymal Stem Cells in Histological Improvement of Cartilage Defect in Wistar Rats 脐带间充质干细胞条件培养基对Wistar大鼠软骨缺损组织学改善的显著作用
IF 1.2
Turkish Journal of Immunology Pub Date : 2018-08-01 DOI: 10.25002/tji.2018.682
Bintang Soetjahjo, Mohammad Hidayat, H. Sujuti, Y. H. Fibrianto
{"title":"The Significant Effect of Conditioned Medium of Umbilical Cord Mesenchymal Stem Cells in Histological Improvement of Cartilage Defect in Wistar Rats","authors":"Bintang Soetjahjo, Mohammad Hidayat, H. Sujuti, Y. H. Fibrianto","doi":"10.25002/tji.2018.682","DOIUrl":"https://doi.org/10.25002/tji.2018.682","url":null,"abstract":"Materials and Methods: Twenty-four of 3-month old male rats that were divided into 6 groups (3 control groups and 3 treatment groups) with different evaluation time (month 2, month 3, and month 4). Treatment in each group was repeated 5 times. The cartilage defect was induced manually and mechanically at the medial condyle of rats’ right femur using a Kirschner Wire (D=1.0 mm; h=1.0 mm). The umbilical cord stem cell cultures were obtained from pregnant rats (19 days). Rats in treatment groups were injected with mesenchymal stem cell-conditioned medium (1 mL/kg BW) 5 times with interval a week after cartilage defect. Histopathological examination of chondrocytes formation and fibrosis tissues was done through Haematoxylin Eosin staining. Data were assessed with O’driscoll scoring and analyzed statistically using Kruskal-Wallis test with SPSS 16.0 software statistically using Kruskal-Wallis Test with SPSS 16.0 software.","PeriodicalId":41088,"journal":{"name":"Turkish Journal of Immunology","volume":"4 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2018-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86300496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Sialik Asit ve İmmün Regülasyondaki Rolü
IF 1.2
Turkish Journal of Immunology Pub Date : 2018-08-01 DOI: 10.25002/tji.2018.610
Nazlı Ecem Dal
{"title":"Sialik Asit ve İmmün Regülasyondaki Rolü","authors":"Nazlı Ecem Dal","doi":"10.25002/tji.2018.610","DOIUrl":"https://doi.org/10.25002/tji.2018.610","url":null,"abstract":"","PeriodicalId":41088,"journal":{"name":"Turkish Journal of Immunology","volume":"439 2","pages":""},"PeriodicalIF":1.2,"publicationDate":"2018-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72457453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Levels of IL-12, IL-17, and LL-37 in Acne Vulgaris 寻常性痤疮中IL-12、IL-17和il -37的水平
IF 1.2
Turkish Journal of Immunology Pub Date : 2018-08-01 DOI: 10.25002/TJI.2018.761
Sinta Murlistyarini, Yasmina Diah Kumala, Yuli Megasasi, Evawani Rahadini
{"title":"Levels of IL-12, IL-17, and LL-37 in Acne Vulgaris","authors":"Sinta Murlistyarini, Yasmina Diah Kumala, Yuli Megasasi, Evawani Rahadini","doi":"10.25002/TJI.2018.761","DOIUrl":"https://doi.org/10.25002/TJI.2018.761","url":null,"abstract":"Introduction: Acne vulgaris (AV) is a chronic inflammatory disease of the pilosebaceous unit with a multifactorial pathogenesis, which includes colonization of Propionibacterium acnes (P. acnes). Increased P. acnes colonization causes a Toll-like receptor (TLR)-2-dependent increase in the production of interleukin (IL)-12 and cathelicidin (LL-37), and a Th-17-dependent increase in interleukin (IL)-17. This study aimed to investigate the relationship between IL-12, IL-17, and LL-37 from patient’s serum and various severities of AV. Materaials and Methods: This study was an analytic observational cross-sectional study. Subjects were enrolled using the consecutive sampling method and assigned according to the Global Acne Grading System (GAGS) criteria. Statistical analysis was performed with one-way analysis of variance and Kruskal-Wallis tests. Results: Mean levels of IL-12, IL-17, and LL-37 in the serum in mild AV were 50.65±6.38, 119.07±24.61, and 180.26±112.92 IU/mL, respectively. The mean levels of IL-12, IL-17, and LL-37 in moderate AV were 47.82±6.51, 132.52±19.41, and 165.91±82.08 IU/mL, respectively. The mean levels of IL-12, IL-17, and LL-37 in severe AV were 48.78±4.93, 208.34±35.38, and 259.50±130.88 IU/mL, respectively. In very severe AV IL-12, IL-17, and LL-37 levels were 39.63, 251.29, and 113 IU/mL, respectively. There were no significant differences between the serum levels of IL12 (p=0.157) and LL-37 (p=0.434) in the different severities of AV, whereas there was a significant association between the serum levels of IL-17 and the severity of AV (p<0.001). Conclusion: IL-17 is associated with severity of acne vulgaris, while no-association was found between the severity of the disease and IL-12 or LL-37.","PeriodicalId":41088,"journal":{"name":"Turkish Journal of Immunology","volume":"61 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2018-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80066248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Metoklopramide Bağlı Olarak Gelişen Kounis Sendrom: Olgu Sunumu
IF 1.2
Turkish Journal of Immunology Pub Date : 2018-08-01 DOI: 10.25002/TJI.2018.717
H. Semiz
{"title":"Metoklopramide Bağlı Olarak Gelişen Kounis Sendrom: Olgu Sunumu","authors":"H. Semiz","doi":"10.25002/TJI.2018.717","DOIUrl":"https://doi.org/10.25002/TJI.2018.717","url":null,"abstract":"","PeriodicalId":41088,"journal":{"name":"Turkish Journal of Immunology","volume":"39 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2018-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74937344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Effect of Monoclonal Antibody to Human Zona Pellucida 3 in Luteineizing Hormone Receptor Expression, Estradiol Levels and de Graaf Follicles Quantity in Mice 人透明带3单克隆抗体对小鼠黄体生成素受体表达、雌二醇水平和卵泡数量的影响
IF 1.2
Turkish Journal of Immunology Pub Date : 2018-08-01 DOI: 10.25002/TJI.2018.463
Dintya Ivantarina, S. Santoso, S. Sutrisno
{"title":"Effect of Monoclonal Antibody to Human Zona Pellucida 3 in Luteineizing Hormone Receptor Expression, Estradiol Levels and de Graaf Follicles Quantity in Mice","authors":"Dintya Ivantarina, S. Santoso, S. Sutrisno","doi":"10.25002/TJI.2018.463","DOIUrl":"https://doi.org/10.25002/TJI.2018.463","url":null,"abstract":"Objective: This research aimed to evaluate effect of monoclonal antibody to human Zona Pellucida 3 (Mab-hZP3) on luteineizing hormone (LH) receptor expression, estradiol levels and de Graaf follicles quantity of mus musculus mice ovaries. Materials and Methods: True experiment post test only control group design was used as research method. Treatments used were control (adjuvant in Tris HCl), and Mab-hZP3 with dosages of 20 μg, 40 μg and 60 μg which tested on day 10, 15 and 20. Luteineizing hormone (LH) receptor, estradiol level and the number of de Graaf follicles measurement were done by immunohistochemical test, ELISA method, and hematoxilin eosin staining, respectively. Results: The results showed that there was no significant difference found on Mab-hZP3 interaction between 20 μg-60 μg dosages and 10–20 days of observation time towards LH receptor expression, estradiol level and and the number of de Graaf follicles. This was related to specificity of monoclonal antibody used. Conclusion: Mab-hZP3 did not lower LH receptor expression, estradiol level and the number of de Graaf follicles quantity, which means that Mab-hZP3 did not interfere at folliculogenesis and not altering hormones profile. It can be concluded that Mab-hZP3 has the potential to be a safe immnocontraception material.","PeriodicalId":41088,"journal":{"name":"Turkish Journal of Immunology","volume":"57 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2018-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77245774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Interferon-gama and Interleukin-4 Expression in Chronic Rhinosinusitis 干扰素- γ和白细胞介素-4在慢性鼻窦炎中的表达
IF 1.2
Turkish Journal of Immunology Pub Date : 2018-08-01 DOI: 10.25002/TJI.2018.564
B. J. Budiman, Surya Azani, Effy Huriyati, D. Irfandy, A. Putra
{"title":"Interferon-gama and Interleukin-4 Expression in Chronic Rhinosinusitis","authors":"B. J. Budiman, Surya Azani, Effy Huriyati, D. Irfandy, A. Putra","doi":"10.25002/TJI.2018.564","DOIUrl":"https://doi.org/10.25002/TJI.2018.564","url":null,"abstract":"Introduction: This study aims is to determine the Interleukin-4 (IL-4) and Interferon-g (IFN-g) expression in Chronic rhinosinusitis (CRS) with and without nasal polyps. Matarial and Methods: In the study, we analyzed the findings of 27 pair pathologic specimens of patients with CRS. Concha nasalis media smear was used to determine the IL-4 and IFN-g expression by real-time polymerase chain reaction (RT-PCR). Data were analyzed by cytokine gene absolute log copy number (CN). Results: Both IL-4 and IFN-g in patients with CRS with nasal polyps CN mean Log of CRS with nasal polyps were higher (15.28±3.92 and 8.54±2.96, respectively) than those of CRS without polyps (14.65±4.65 and 7.57±1.82, respectively), but this was not statistically significant (p=0.596, 0.346 respectively). Conclusion: IL-4 and IFN-g absolute expression level are higher in CRS with nasal polyps than those who had CRS without nasal polyps, but this was not statistically significant (p>0.05).","PeriodicalId":41088,"journal":{"name":"Turkish Journal of Immunology","volume":"2017 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2018-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81002544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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