Turkish Journal of Immunology最新文献

{"title":"CXCR5+CD8+ Follicular Cytotoxic T Cell Biology and Its Relationship with Diseases","authors":"Nurten Sayın Ekinci, Ş. Darbaş, F. Uçar","doi":"10.4274/tji.galenos.2022.04796","DOIUrl":"https://doi.org/10.4274/tji.galenos.2022.04796","url":null,"abstract":"","PeriodicalId":41088,"journal":{"name":"Turkish Journal of Immunology","volume":"1 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2022-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89971969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Potential Neuroinvasion Mechanism of SARS-CoV-2","authors":"A. Şahin, S. Korkunç, Fatıma Hacer Kurtoğlu, Hilal Taskiran, Betigul Ekmekci, Huseyn Babayev, A. Ekmekci","doi":"10.4274/tji.galenos.2022.80774","DOIUrl":"https://doi.org/10.4274/tji.galenos.2022.80774","url":null,"abstract":"The severe acute respiratory syndrome coronavirus-2, a coronavirus, is known to cause acute respiratory distress syndrome and a range of non)respiratory effects, particularly in elderly male patients with underlying health conditions such overweight, diabetes, and hypertension. The coronavirus disease-2019 sequelae include multiple organ failure and neurological issues, and these prior health issues are linked to endothelial dysfunction. Although inhalation is the most frequent mode of infection, this virus has also been discovered in neurons, cerebrospinal fluid, the choroid plexus, and meningeal vasculature (English) [ FROM AUTHOR] Bir koronavirüs olan şiddetli akut solunum yolu sendromu koronavirüsü-2’nin, özellikle obezite, diyabet ve hipertansiyon gibi sağlık sorunları olan yaşlı erkek hastalarda akut solunum sıkıntısı sendromuna ve bir dizi solunum dışı sekellere neden olduğu bilinmektedir. Bu sağlık sorunları endotel disfonksiyonla bağlantılıdır ve koronavirüs hastalığı-2019 sekelleri, çoklu organ yetmezliği ve nörolojik sorunları içerir. Solunum birincil enfeksiyon modu olsa da, bu virüs koroid pleksus ve meningeal arterlerin yanı sıra nöronlar ve beyin omurilik sıvısı dahil olmak üzere çeşitli organlarda keşfedilmiştir (Turkish) [ FROM AUTHOR] Copyright of Turkish Journal of Immunology is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full . (Copyright applies to all s.)","PeriodicalId":41088,"journal":{"name":"Turkish Journal of Immunology","volume":"66 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2022-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83825910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Anti-Inflammatory Effects of the Nutrition Bio-Shield (NBS) Supplement Intake on Adjuvant-Induced Rheumatoid Arthritis in Rat","authors":"M. Mosadegh, A. Khalkhali, Yasaman Sadeghi, Y. Erfani","doi":"10.4274/tji.galenos.2022.03522","DOIUrl":"https://doi.org/10.4274/tji.galenos.2022.03522","url":null,"abstract":"","PeriodicalId":41088,"journal":{"name":"Turkish Journal of Immunology","volume":"107 S2","pages":""},"PeriodicalIF":1.2,"publicationDate":"2022-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72393851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fear of COVID-19 among Healthcare Workers of a Tertiary Care Cardiac Facility Before- and After-Vaccination and Serology","authors":"J. Shah, A. Ammar, Waqar Khan, Rajesh Kumar, F. Ali, Shahid Ahmed, Mehwish Zehra, J. Sial, T. Saghir, Z. Rehman","doi":"10.4274/tji.galenos.2022.63935","DOIUrl":"https://doi.org/10.4274/tji.galenos.2022.63935","url":null,"abstract":"Objective: This study aimed to assess the changes in the perceptions and practices during the coronavirus disease-2019 (COVID-19) era before and after vaccination and antibodies titer among the healthcare workers (HCWs) at a tertiary care cardiac center. Materials and Methods: This descriptive study included HCWs working at a tertiary care cardiac center in Karachi, Pakistan. A predefined structured questionnaire was used to assess the sense of security, practice, and perception of the HCWs before vaccination, after vaccination, and after knowing the antibodies titer. Results: Out of 151 HCWs, 70.2% (106) were male, and a majority, 65.6% (99), were ≤35 years old with an overall mean age of 34.92 ± 7.64 years. Nearly half of the individuals, (n=74;49%), were doctors, 10 individuals (6.6%) were non-clinical staff, and reaming were nursing staff. The mean day since COVID-19 vaccination was 89.6 ± 40.07 before COVID-19 infection. Antibodies titer levels were >250 U/mL in 108 cases (71.5%) and ≤100 U/mL in 18 cases (11.8%). A significant increase in perception score was observed after serology with a mean of 61.04 ± 25.23 vs 53.86 ± 28.96;(p=0.008) compared to the post-vaccination perception score. A significant declining trend has been witnessed in mean practice scores, with a pre-vaccination mean of 69.93 ± 27.12, post-vaccination mean of 59.47 ± 30.61 (p<0.001). And post-serology mean of 55.1 ± 27.1 (p<0.001). Conclusion: An increase in the sense of security and leniency in adherence to personal protective measures has been observed among HCWs after vaccination and after knowing the antibodies titer (English) [ FROM AUTHOR] Amaç: Bu çalışmada, üçüncü basamak bir kalp merkezindeki sağlık çalışanları arasında koronavirüs hastalığı-2019 (COVID-19) döneminde aşılama öncesi ve sonrası algı ve uygulamalardaki değişikliklerinin ve antikor titrelerinin değerlendirilmesi amaçlanmıştır. Gereç ve Yöntem: Bu tanımlayıcı çalışma, Pakistan, Karaçi’deki üçüncü basamak bir kalp merkezindeki sağlık çalışanlarını içermektedir. Sağlık çalışanlarının aşılamadan önce, aşılamadan sonra ve antikor titresini öğrendikten sonra güvenlik hissi, uygulama ve algılarını değerlendirmek için önceden tanımlanmış yapılandırılmış bir anket kullanılmıştır. Bulgular: Yüz elli bir sağlık çalışanının %70.2 (n=106) erkek ve katılımcıların çoğunluğu, %65.6 (n=99) 35 yaşında ya da daha geç yaştaydı ve ortalama yaş 34.92 ± 7.64 yıl olarak saptandı. Neredeyse yarısı, (n=74;%49) hekim ve %6.6 (n=10) klinik dışı personel, geri kalan kişiler hasta bakım personeli görevindeydi. Önceki COVID-19 enfeksiyonu, doğası gereği 10 kişide (%6.6) ciddi, 1 kişide (%0.7) kritik olmak üzere 62 kişide (%41.1) rapor edilmiştir. COVID-19 aşılamasından bu yana geçen ortalama gün sayısı 89.6 ± 40.07 ve 11 kişide (%7.3) aşılama sonrası COVID-19 bildirildi. Antikor titre seviyeleri 108 kişide (%71.5) >250 U/mL ve 18 kişide ise (%11.9) ≤100 U/mL ve altında saptandı. Aşılama sonrası algı puanı ile karşılaştırıldığınd","PeriodicalId":41088,"journal":{"name":"Turkish Journal of Immunology","volume":"106 S115","pages":""},"PeriodicalIF":1.2,"publicationDate":"2022-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72408095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Hypoxia Affects the Main Thymocyte Subset Distributions in Congenital Heart Diseases","authors":"E. Orlova, O. Loginova, Natalia Loginova, R. Shekhmametyev, S. Shirshev","doi":"10.4274/tji.galenos.2022.92485","DOIUrl":"https://doi.org/10.4274/tji.galenos.2022.92485","url":null,"abstract":"","PeriodicalId":41088,"journal":{"name":"Turkish Journal of Immunology","volume":"17 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2022-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72503650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Cytokine Signal Suppressor Gene Polymorphisms in Turkish Patients with Active Tuberculosis","authors":"Leyla Ersoy, A. Özçimen, Mahmut Ülger, M. Çalıkoğlu, G. Aslan","doi":"10.4274/tji.galenos.2021.09709","DOIUrl":"https://doi.org/10.4274/tji.galenos.2021.09709","url":null,"abstract":"","PeriodicalId":41088,"journal":{"name":"Turkish Journal of Immunology","volume":"153 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2021-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77799326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Evaluation of Vaccine Hesitancy and Refusal for Childhood Vaccines and the COVID-19 Vaccine in Individuals Aged Between 18 and 25 Years","authors":"Gonca P. Soysal, E. Durukan, R. Akdur","doi":"10.4274/tji.galenos.2021.35229","DOIUrl":"https://doi.org/10.4274/tji.galenos.2021.35229","url":null,"abstract":"Objective: The aim of this study is to determine vaccine hesitancy and refusal for childhood vaccines and the Coronavirus disease-2019 (COVID-19) vaccine in individuals aged between 18 and 25 years and the affecting factors. Materials and Methods: In this descriptive study, an online questionnaire was implemented on 1.033 people aged between 18 and 25 years and living in Turkey between January 28, 2021, and February 19, 2021, by reaching them via e-mail and messaging applications. Results: Among the participants, 68.8% considered getting their children vaccinated, 11.4% were hesitant and 3.1% refused. Among the participants, 36.6% considered getting vaccinated against COVID-19, 34.8% hesitated and 28.6% refused. Hesitation/rejection of childhood vaccines increased with age and when negative information about childhood vaccines was obtained. The acceptance of the COVID-19 vaccine was higher in men, in those who assumed that the COVID-19 virus was of a natural origin, in those who obtained information on the COVID-19 vaccine from the Ministry of Health, and in those who made search in scientific papers. Conclusion: The rates of hesitation and rejection in the COVID-19 vaccines are quite high compared to childhood vaccines. It shows that participants are influenced by speculative news. Therefore, it is recommended that this age group be given trainings based on scientific evidence regarding both childhood vaccines and the benefits of the COVID-19 vaccine.","PeriodicalId":41088,"journal":{"name":"Turkish Journal of Immunology","volume":"44 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2021-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72619176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Friend or Foe? The Potential Roles of Innate Lymphoid Cells in Lung Transplantation","authors":"H. Bulut, A. Turna","doi":"10.4274/tji.galenos.2021.69885","DOIUrl":"https://doi.org/10.4274/tji.galenos.2021.69885","url":null,"abstract":"","PeriodicalId":41088,"journal":{"name":"Turkish Journal of Immunology","volume":"26 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2021-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84039079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is There a Need for Such a Naming: Seronegative Primary Sjogren’s Syndrome?","authors":"S. Karahan, Aycan Karabulut","doi":"10.4274/tji.galenos.2021.85047","DOIUrl":"https://doi.org/10.4274/tji.galenos.2021.85047","url":null,"abstract":"","PeriodicalId":41088,"journal":{"name":"Turkish Journal of Immunology","volume":"84 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2021-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82599038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"mRNA Expression Levels of NKp30, NKp46, NKG2D, Perforin and Granzyme in the Behçet’s Disease","authors":"M. Gelmez, S. Cinar, E. Aktas, F. Oktelik, Goncagul Babuna-kobaner, M. Erdugan, A. Gül, A. Kose, G. Deniz","doi":"10.5222/tji.2021.03521","DOIUrl":"https://doi.org/10.5222/tji.2021.03521","url":null,"abstract":"","PeriodicalId":41088,"journal":{"name":"Turkish Journal of Immunology","volume":"40 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77907766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}