Journal of Basic and Clinical Health Sciences最新文献_第8页

Determination of Anxiety Levels and Knowledge Levels about COVİD-19 during COVİD-19 Outbreak of Pregnants: Survey in Turkey 确定COVİD-19暴发期间孕妇对COVİD-19的焦虑水平和知识水平:土耳其调查

IF 0.2

Journal of Basic and Clinical Health Sciences Pub Date : 2023-01-02 DOI: 10.30621/jbachs.1004905

Özlem Doğan Yüksekol, Feyza Nazik, N. Baltacı, M. Ulucan

{"title":"Determination of Anxiety Levels and Knowledge Levels about COVİD-19 during COVİD-19 Outbreak of Pregnants: Survey in Turkey","authors":"Özlem Doğan Yüksekol, Feyza Nazik, N. Baltacı, M. Ulucan","doi":"10.30621/jbachs.1004905","DOIUrl":"https://doi.org/10.30621/jbachs.1004905","url":null,"abstract":"Purpose: To determine the fears and level of knowledge of pregnant women about outbreaks during the COVID 19 outbreak. \u0000Methods: This was conducted as descriptive research with 276 pregnant women admitted to women's health and maternity outpatient clinic of hospitals in eastern Turkey. The data was collected using the personal information form, the information levels form for COVID-19, and the COVID-19 Anxiety Scale. \u0000Results: It was found that 75.4% of pregnant women were worried that they would catch coronavirus in the hospital during or after childbirth. The average score of women on the COVID-19 Anxiety Scale was 6.7±2.4 (min:5, max:14). The anxiety level of the pregnant women who were in the last trimester of pregnancy, who did not receive information about COVID-19, who changed their delivery method due to the pandemic, who received inadequate prenatal care, whose social support decreased, and who felt vulnerable, were significantly higher. \u0000Conclusions: The research revealed that anxiety in pregnant women is affected by some factors. It is important to provide care and support for these groups.","PeriodicalId":40972,"journal":{"name":"Journal of Basic and Clinical Health Sciences","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47766575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hyperbaric Pressure Effect on Dental Luting Cements 高压对牙胶的影响

IF 0.2

Journal of Basic and Clinical Health Sciences Pub Date : 2022-12-31 DOI: 10.30621/jbachs.1187298

Secil Ozkan Ata, N. Ata, Rıfat Uğurlutan

{"title":"Hyperbaric Pressure Effect on Dental Luting Cements","authors":"Secil Ozkan Ata, N. Ata, Rıfat Uğurlutan","doi":"10.30621/jbachs.1187298","DOIUrl":"https://doi.org/10.30621/jbachs.1187298","url":null,"abstract":"Background and Purpose: The aim of this study was to evaluate the flexural strength values of five luting cements that are commonly used in dental restorations after exposed to hyperbaric pressure. \u0000Methods: Five luting cements (polycarboxylate cement, glass ionomer luting cement, manual-mixed resin cement, and two auto-mixed resin cement) were prepared. (25 x 2 x 2 mm3) (n=16 for each) The specimens were divided into two subgroups (n=8) and were exposed to hyperbaric pressure (3 ATM) 20 times for 30 minutes. The control groups stored in ambient pressure. Universal testing machine was used for flexural strength measurement with a crosshead speed of 1 mm/min. \u0000Results: One-way ANOVA test was used for statistical analysis, the differences in flexural strength values were additionally evaluated by Weibull Analysis. Glass ionomer and polycarboxylate cement were the most effected resins from hyperbaric pressure changes. Regardless of the pressure changes, the highest flexural strength values were seen for the self-adhesive resin cements and polycarboxylate cement showed the lowest strength value. \u0000Conclusion: Resin cements can be used for cementation of the dental restorations in divers and individuals who are subjected to hyperbaric pressure.","PeriodicalId":40972,"journal":{"name":"Journal of Basic and Clinical Health Sciences","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44109933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Monocyte-to-HDL Cholesterol Ratio As A New Parameter of Systemic Inflammation and Disease Severity in Treatment-Resistant Chronic Spontaneous Urticaria 单核细胞与高密度脂蛋白胆固醇比值作为慢性顽固性荨麻疹全身炎症和疾病严重程度的新指标

IF 0.2

Journal of Basic and Clinical Health Sciences Pub Date : 2022-12-30 DOI: 10.30621/jbachs.1210134

Özge Kaya, Selda Işık Mermutlu

{"title":"Monocyte-to-HDL Cholesterol Ratio As A New Parameter of Systemic Inflammation and Disease Severity in Treatment-Resistant Chronic Spontaneous Urticaria","authors":"Özge Kaya, Selda Işık Mermutlu","doi":"10.30621/jbachs.1210134","DOIUrl":"https://doi.org/10.30621/jbachs.1210134","url":null,"abstract":"Background and Purpose: Chronic spontaneous urticaria (CSU) is characterized by inflammation and increased oxidative stress in its pathogenesis. The study aims to evaluate new inflammatory markers indicating systemic inflammation in resistant CSU and to determine their relationship with disease severity. \u0000Methods: The files of CSU patients and matched healthy volunteers were reviewed and compared in terms of demographics, medical history, clinical features, laboratory parameters, and new inflammatory markers [NLR:neutrophil-lymphocyte ratio, MLR: monocyte-lymphocyte ratio, MHR:monocyte-to-high-density lipoprotein cholesterol (HDL-C)]. \u0000Results: Sixty-one CSU patients and 50 healthy controls were evaluated (female: male ratio=1.9:1, mean age=43.97 ± 14.88 years). The median erythrocyte sedimentation rate, C-reactive protein (CRP), white blood cell, monocyte count, and MHR were higher in the CSU group; in contrast, the mean HDL-C level was lower. The median NLR and MLR were also higher in the CSU group but were not statistically significant. Urticaria activity score 7 (UAS7) was positively correlated with MHR and negatively correlated with HDL-C. MHR was positively correlated with MLR, CRP, and UAS7. \u0000Conclusions: MHR might serve as an indicator of inflammation intensity and predisposition to MS in CSU patients. It might also be used as an objective tool for evaluating disease severity and treatment response in CSU.","PeriodicalId":40972,"journal":{"name":"Journal of Basic and Clinical Health Sciences","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49432101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Novel Approach to the Hedgehog Signaling Pathway: Combined Treatment of SMO and PTCH Inhibitors Hedgehog信号通路的新途径：SMO和PTCH抑制剂的联合治疗

IF 0.2

Journal of Basic and Clinical Health Sciences Pub Date : 2022-12-30 DOI: 10.30621/jbachs.1193720

Aslıhan Karadağ, Y. Başbınar

{"title":"Novel Approach to the Hedgehog Signaling Pathway: Combined Treatment of SMO and PTCH Inhibitors","authors":"Aslıhan Karadağ, Y. Başbınar","doi":"10.30621/jbachs.1193720","DOIUrl":"https://doi.org/10.30621/jbachs.1193720","url":null,"abstract":"Purpose: Abnormal Sonic Hedgehog signaling Pathway (Shh) activation is crucial for development of cancer stem cells, neoplastic growth and epithelial-mesenchymal transition processes in adulthood. Activation of Hedgehog signaling pathway may induces the changes in cilia found in the cell membrane, iniciates the Gli1 transcription factor that is translocated to the cell nucleus and finally, the target genes are transcribed. In this study, invastigation of the antiproliferative, anti-invasive and antimigrative effect of the combined use of robotnikinin (Ptch1 antagonist) and vismodegib (Smo inhibitor) on the hedgehog signaling pathway was aimed. \u0000 \u0000Material and Methods: After demonstarting the presence of the hedgehog signaling pathway in the glioblastoma cell line U87-MG, the effect of the combined use of the robotnikinin and the vismodegib on the hedgehog signaling pathway was investigated. In-vitro cell proliferation, migration, and invasion analysis of the combination of antagonist and inhibitor and in silico drug-likeness analysis were performed. \u0000 \u0000Results: Two different combinations of robotnikinin and vismodegib were tested. In vitro studies show that the combined use of agents in combined treatments of Smo and Ptch1is more effective than their individual usage. \u0000 \u0000Conclusion: Inhibition of the hedgehog signaling pathway with specific inhibitors and antagonists is considered an innovative strategy for cancer therapy.","PeriodicalId":40972,"journal":{"name":"Journal of Basic and Clinical Health Sciences","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42511753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

The Effect of Coronovirus Perceptions and Attitudes of Pediatric Nurses on Quality of Life 儿科护士冠状病毒认知和态度对生活质量的影响

IF 0.2

Journal of Basic and Clinical Health Sciences Pub Date : 2022-12-30 DOI: 10.30621/jbachs.1035474

Bahar Çolak, İ. Kahriman, Kübra Tunçel

{"title":"The Effect of Coronovirus Perceptions and Attitudes of Pediatric Nurses on Quality of Life","authors":"Bahar Çolak, İ. Kahriman, Kübra Tunçel","doi":"10.30621/jbachs.1035474","DOIUrl":"https://doi.org/10.30621/jbachs.1035474","url":null,"abstract":"Purpose: This cross-sectional study aims to explore the effect of pediatric nurses' perceptions and attitudes of coronavirus on their quality of life. \u0000Methods: It was carried out between the dates of June-August, 2021. The sample of the study consisted of 80 pediatric nurses working in the pediatric clinics of a university hospital. “Perceptions and Attitudes Evaluation Scale towards the COVID-19 Pandemic” and \"WHOQOL-BREF-TR Scale\" were used to collect data which were collected by online survey method. \u0000Results: It was determined that the mean score of the spiritual and social domains of the quality of life of the pediatric nurses was at a moderate level, while the mean scores of the physical and environmental domains were found to be below the medium level. According to the results of the regression analysis, the nurses' coronavirus perception and attitude sub-dimensions of dangerousness, macro, cognitive avoidance, common area avoidance and personal contact avoidance scores explained 30% of spiritual domain scores, and macro and common area avoidance sub-dimension scores explained 25% of social domain scores, macro and complo sub-dimensions scores explained 22% of environmental domain scores. \u0000Conlusion: As a result, it was determined that pediatric nurses' perceptions and attitudes towards coronavirus effect their quality of life. In order to increase the quality of life of pediatric nurses, attempts should be made to help nurses in the conditions of the COVID-19 pandemic and to provide necessary protection conditions to minimize the physical, spiritual, social, and environmental effects of the pandemic.","PeriodicalId":40972,"journal":{"name":"Journal of Basic and Clinical Health Sciences","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46761587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Can Oncology Nursing Education Change the Attitude of Nursing Students toward Cancer (Cancer Stigma)? A Quasi-Experimental Study 肿瘤护理教育能改变护生对癌症（癌症耻辱）的态度吗？准实验研究

IF 0.2

Journal of Basic and Clinical Health Sciences Pub Date : 2022-12-28 DOI: 10.30621/jbachs.958583

E. Karadağ, Ö. Uğur

{"title":"Can Oncology Nursing Education Change the Attitude of Nursing Students toward Cancer (Cancer Stigma)? A Quasi-Experimental Study","authors":"E. Karadağ, Ö. Uğur","doi":"10.30621/jbachs.958583","DOIUrl":"https://doi.org/10.30621/jbachs.958583","url":null,"abstract":"Purpose: This study was conducted to assess the effect of the oncology nursing internship education on the attitudes of students (stigma) toward cancer patients. The study was conducted in a faculty of nursing in İzmir, Turkey. \u0000Methods: The quasi-experimental pre-test post-test design was used in this study. The sample of the study was composed of totally 84 students, who attended the course of Oncology Nursing Internship (n:43) and the course of Gynaecology and Obstetrics Nursing Internship (n:41). The Student Information Form and Questionnaire for Measuring Attitudes Toward Cancer - Community Version were used as the data collection tool in the study. The students who were interns in oncology nursing received an education on oncology nursing including 280 hours of practice and 56 hours of theory and the other group had no education on the subject. In order to assess the efficiency of the education of oncology nursing internship on cancer attitude and to compare the groups, The Questionnaire for Measuring Attitudes Toward Cancer - Community Version was applied again to both groups at the end of the semester. \u0000Results: As a result of this study, it was found that the course of oncology nursing internship increased the positive attitudes of the students toward cancer patients (t=5.591, p=0.000). \u0000Conclusion: The education programs of oncology nursing should be integrated into the nursing curricula to provide that nursing students provide more effective care services for cancer patients and develop more positive attitudes.","PeriodicalId":40972,"journal":{"name":"Journal of Basic and Clinical Health Sciences","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45346414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of Tumor Burden Response to Single-cycle of Lu-177 PSMA Treatment with Whole Body Scintigraphic Planar Images in Prostate Cancer Patients 用全身闪烁平面图像评价癌症患者对Lu-177 PSMA单周期治疗的肿瘤负荷反应

IF 0.2

Journal of Basic and Clinical Health Sciences Pub Date : 2022-12-28 DOI: 10.30621/jbachs.1189713

E. Acar, A. Aksu, Ender Berat Ellidokuz, Y. Başbınar, G. Çapa Kaya

引用次数: 0

Environmental sustainability, a holistic view from health sector perspective 环境可持续性，从卫生部门角度的整体观点

IF 0.2

Journal of Basic and Clinical Health Sciences Pub Date : 2022-12-26 DOI: 10.30621/jbachs.1085032

Hina Zahoor

引用次数: 0

Effects of Homeopathic Remedies on Mesenchymal Stem Cell Proliferation: A Methodology Study 顺势疗法对间充质干细胞增殖影响的方法学研究

IF 0.2

Journal of Basic and Clinical Health Sciences Pub Date : 2022-12-26 DOI: 10.30621/jbachs.1210789

Ahu Pakdemirli, M. Sarper, E. Kazanci

{"title":"Effects of Homeopathic Remedies on Mesenchymal Stem Cell Proliferation: A Methodology Study","authors":"Ahu Pakdemirli, M. Sarper, E. Kazanci","doi":"10.30621/jbachs.1210789","DOIUrl":"https://doi.org/10.30621/jbachs.1210789","url":null,"abstract":"Background and purpose: Mesenchymal stem cells are multipotent cells of mesodermal origin, \u0000which have the ability to differentiate into other cells in the bone marrow microenvironment under \u0000suitable conditions in vitro. Homeopathy is a holistic practice method that aims to improve health \u0000status with personalized homeopathic medicines. At the same time, it is among the certified training \u0000programs of the Traditional and Complementary Medicine Practices of the Ministry of Health. Studies \u0000evaluating the effect of homeopathic remedies in the field of stem cells are rarely encountered in the \u0000literature. As a matter of fact, the material and method parts of these studies are not clear enough. In \u0000our study, the methodology of working with mesenchymal stem cells of homeopathic remedies has \u0000been presented in detail and it has been aimed to observe their proliferative effects. \u0000 \u0000Material and Methods: Mesenchymal stem cells were exposed to 10%, 20%, 50% and 100% ratios \u0000of homeopathic remedies (30°C potency: Aloe, Calendula, Hypericum, Staphysagria) for 24 and 48 \u0000hours. The percent viability of cells at 24 and 48 hours was evaluated with the MTT (3-4,5-dimethyl- \u0000thiazolyl-2,5-diphenyltetrazolium bromide) test. \u0000 \u0000Results: Aloe vera C 30 – Staphysagria C30 – Calencula C30 – Hypericum C30 remedies were found \u0000to have an effect on mesenchymal stem cell proliferation at all doses, and the results were statistically \u0000more significant when maintained in 10% media. \u0000 \u0000Conclusion: It is thought that the methodology used in this study on working methods with \u0000homeopathic remedies will contribute to the literature and many scientific studies to be done in the \u0000future.","PeriodicalId":40972,"journal":{"name":"Journal of Basic and Clinical Health Sciences","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49300053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of Force Sense, Functional Performance, Quality of Life, Activity Level and Kinesiophobia in Degenerative Meniscal Tears Following Partial Meniscectomy 部分半月板切除术后退化性半月板撕裂的力觉、功能表现、生活质量、活动水平和运动恐惧症的评估

IF 0.2

Journal of Basic and Clinical Health Sciences Pub Date : 2022-12-26 DOI: 10.30621/jbachs.1155794

Cansu Gevrek, Ahmet Atay, G. Kınıklı

引用次数: 0