Therapeutic Advances in Gastrointestinal Endoscopy最新文献

{"title":"Metallic stent insertion to relieve malignant bowel obstruction in a child: a case report.","authors":"Sundus Bilal,&nbsp;Saad M Saeed,&nbsp;Muhammad Z Sidique,&nbsp;Muhammed A Yusuf","doi":"10.1177/26317745221111942","DOIUrl":"https://doi.org/10.1177/26317745221111942","url":null,"abstract":"<p><p>Self-expandable metallic stents (SEMS) have been widely used in adults to relieve obstruction secondary to colorectal tumours. However, there is a paucity of literature about their use in children, with only a few case reports describing stent insertion in children with benign colonic conditions. There is one case report on a malignant colonic condition in a child by Hussain <i>et al</i>. in the literature. However, due to the rarity of the condition, there are currently no guidelines from learned societies on colorectal SEMS placement in paediatric patients. We share our experience of using a fully covered SEMS to relieve malignant colonic obstruction in a 6 year-old-child, who was on treatment for T cell lymphoma. This was done as a bridge to surgery, thereby allowing planned surgery, and avoiding colostomy in this child, who went on to have colonic resection with primary anastomosis.</p>","PeriodicalId":40947,"journal":{"name":"Therapeutic Advances in Gastrointestinal Endoscopy","volume":" ","pages":"26317745221111942"},"PeriodicalIF":2.6,"publicationDate":"2022-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/f3/a7/10.1177_26317745221111942.PMC9290144.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40524546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management of biliary stones in bariatric surgery.","authors":"Francisco Tustumi,&nbsp;João Emílio Lemos Pinheiro Filho,&nbsp;Lucas Cata Preta Stolzemburg,&nbsp;Leonardo Carvalho Serigiolle,&nbsp;Thiago Nogueira Costa,&nbsp;Denis Pajecki,&nbsp;Marco Aurélio Santo,&nbsp;Sérgio Carlos Nahas","doi":"10.1177/26317745221105087","DOIUrl":"https://doi.org/10.1177/26317745221105087","url":null,"abstract":"<p><p>Morbidly obese and post-bariatric surgery patients are at increased risk for biliary stones formation. The complications related to biliary stones may impose complexity on their management. This study aimed to review the management of biliary conditions in obese and bariatric patients. In this study, a narrative review was performed of the medical, surgical, and endoscopic procedures for the management of biliary stones and their related complications. Knowing the main prophylactic and therapeutic interventions options is essential for clinicians to properly manage the biliary stones in patients candidates or submitted to bariatric surgery.</p><p><strong>Plain language summary: </strong><b>Management of biliary stones in bariatric surgery</b> The complications related to biliary stones may impose complexity on their management. Knowing the main prophylactic and therapeutic intervention options is essential for clinicians to properly manage the biliary stones in patient candidates or submitted to bariatric surgery. This study reviewed the main tools clinicians can handle to properly manage candidates for bariatric surgery or patients submitted to bariatric surgery.</p>","PeriodicalId":40947,"journal":{"name":"Therapeutic Advances in Gastrointestinal Endoscopy","volume":" ","pages":"26317745221105087"},"PeriodicalIF":2.6,"publicationDate":"2022-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/cd/09/10.1177_26317745221105087.PMC9664186.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40709290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictors of postoperative recurrence in a cohort of Tunisian patients with Crohn's disease.","authors":"Aya Hammami,&nbsp;Raida Harbi,&nbsp;Nour Elleuch,&nbsp;Khaled Ben Meddeb,&nbsp;Wafa Ben Ameur,&nbsp;Wafa Dahmani,&nbsp;Ahlem Braham,&nbsp;Salem Ajmi,&nbsp;Mehdi Ksiaa,&nbsp;Aida Ben Slama,&nbsp;Hanen Jaziri,&nbsp;Ali Jmaa","doi":"10.1177/26317745211060689","DOIUrl":"https://doi.org/10.1177/26317745211060689","url":null,"abstract":"<p><strong>Background: </strong>The aim of our study was to evaluate the frequency and risk factors of clinical postoperative recurrence in Tunisian patients with Crohn's disease (CD).</p><p><strong>Methods: </strong>Clinical data of 86 patients with CD who underwent ileocolonic resection at University Hospital of Sahloul in Tunisia were retrospectively reviewed. Continuous data are expressed as median (interquartile range), and categorical data as frequencies and percentages. Multivariate Cox proportional hazard regression analysis was conducted to identify the risk factors of postoperative clinical recurrence.</p><p><strong>Results: </strong>A total of 86 patients with CD were included in this study. During follow-up, 21 patients (24.4%) had clinical recurrence. The cumulative clinical recurrence rate was 9.3% at 1 year and 20.9% at 5 years. In univariate analysis, predictive factors of postoperative clinical recurrence were active preoperative smoking (<i>p</i> = 0.008), ileal location of the disease (<i>p</i> = 0.01), active CD [Crohn's Disease Activity Index (CDAI) > 150] (<i>p</i> = 0.04), duration of disease before first surgery <9.5 months (<i>p</i> = 0.027), and limited resection margins (<2 cm) from macroscopically diseased bowel (<i>p</i> = 0.005). In multivariate analysis, only smoking (<i>p</i> = 0.012), duration of disease before first surgery <9.5 months (<i>p</i> = 0.048), and limited resection margins (<2 cm) from macroscopically diseased bowel (<i>p</i> = 0.046) were confirmed to be independent factors of clinical relapse.</p><p><strong>Conclusion: </strong>Smoking, duration of disease before first surgery <9.5 months, and limited resection margins (<2 cm) from macroscopically diseased bowel were independent risk factors for clinical recurrence. Based on these factors, patients could be stratified in order to guide postoperative therapeutic options.</p>","PeriodicalId":40947,"journal":{"name":"Therapeutic Advances in Gastrointestinal Endoscopy","volume":" ","pages":"26317745211060689"},"PeriodicalIF":2.6,"publicationDate":"2022-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/85/f8/10.1177_26317745211060689.PMC8935554.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40314607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Therapeutic utility of percutaneous cecostomy in adults: an updated systematic review.","authors":"Yasir Mohammed Khayyat","doi":"10.1177/26317745211073411","DOIUrl":"https://doi.org/10.1177/26317745211073411","url":null,"abstract":"<p><strong>Objective: </strong>Percutaneous cecostomy is a minimally invasive procedure that provides access to the colon for therapeutic interventions. This review aimed to update and summarize the existing information on the use and application of percutaneous endoscopic cecostomy in the field of therapeutic gastroenterology.</p><p><strong>Data sources: </strong>A systematic review of the literature was performed without any restrictions on the year of publication from the date of inception in 1986 to January 2021.</p><p><strong>Methods: </strong>The review was performed using the medical subject heading keywords in the following search engines: MEDLINE, EMBASE, Cochrane, and Google Scholar.</p><p><strong>Results: </strong>A total of 29 articles were subjected to final data extraction. The review included a total of 174 patients who underwent percutaneous cecostomy. Most of the included studies were conducted in the United States (<i>n</i> = 14). The most common comorbidity was cancer (<i>n</i> = 10) and the major indication for performing percutaneous cecostomy was colonic pseudo-obstruction or Ogilvie's syndrome (<i>n</i> = 15). The main technique for performing percutaneous cecostomy was endoscopy (17 studies), followed by fluoroscopy- (five studies), computed-tomography- (three studies), laparoscopy- (two studies), and ultrasound- (one study) guided procedures. The procedure was technically successful in 153 (88%) cases. The total cumulative rates of major and minor complications were 47.5%. These complications included tube malfunction, local wound site infections, and bleeding and rare complications of peritonitis and death.</p><p><strong>Conclusion: </strong>Percutaneous cecostomy is a safe and effective option for managing acute colonic pseudo-obstruction. It leads to durable symptom relief with low to minimal risk.</p>","PeriodicalId":40947,"journal":{"name":"Therapeutic Advances in Gastrointestinal Endoscopy","volume":" ","pages":"26317745211073411"},"PeriodicalIF":2.6,"publicationDate":"2022-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/12/64/10.1177_26317745211073411.PMC8819810.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39767389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Serrated polyp detection rate in colonoscopies performed by gastrointestinal fellows.","authors":"Matthew Heckroth,&nbsp;Michael Eiswerth,&nbsp;Mohamed Elmasry,&nbsp;Khushboo Gala,&nbsp;Wenjing Cai,&nbsp;Scott Diamond,&nbsp;Amal Shine,&nbsp;David Liu,&nbsp;Nanlong Liu,&nbsp;Sudaraka Tholkage,&nbsp;Maiying Kong,&nbsp;Dipendra Parajuli","doi":"10.1177/26317745221136775","DOIUrl":"https://doi.org/10.1177/26317745221136775","url":null,"abstract":"<p><strong>Background: </strong>Clinically significant serrated polyp detection rate (CSSDR) and proximal serrated polyp detection rate (PSDR) have been suggested as the potential quality benchmarks for colonoscopy (CSSDR = 7% and PSDR = 11%) in comparison to the established benchmark adenoma detection rate (ADR). Another emerging milestone is the detection rate of lateral spreading lesions (LSLs).</p><p><strong>Objectives: </strong>This study aimed to evaluate CSSDR, PSDR, ADR, and LSL detection rates among gastrointestinal (GI) fellows performing a colonoscopy. A secondary aim was to evaluate patient factors associated with the detection rates of these lesions.</p><p><strong>Design and methods: </strong>A retrospective review of 799 colonoscopy reports was performed. GI fellow details, demographic data, and pathology found on colonoscopy were collected. Multiple logistic regression analysis was performed to identify the factors associated with CSSDR, PSDR, ADR, and LSL detection rates. A <i>p</i> value < 0.05 was considered statistically significant.</p><p><strong>Results: </strong>For our patient population, the median age was 58 years; 396 (49.8%) were male and 386 (48.6%) were African American. The 15 GI fellows ranged from first (F1), second (F2), or third (F3) year of training. We found an overall CSSDR of 4.4%, PSDR of 10.5%, ADR of 42.1%, and LSL detection rate of 3.2%. Female gender was associated with CSSDR, while only age was associated with PSDR. GI fellow level of training was associated with LSL detection rate, with the odds of detecting them expected to be four times higher in F2/F3s than F1s.</p><p><strong>Conclusion: </strong>Although GI fellows demonstrated an above-recommended ADR and nearly reached target PSDR, they failed to achieve target CSSDR. Future studies investigating a benchmark for LSL detection rate are needed to quantify if GI fellows are detecting these lesions at adequate rates.</p>","PeriodicalId":40947,"journal":{"name":"Therapeutic Advances in Gastrointestinal Endoscopy","volume":"15 ","pages":"26317745221136775"},"PeriodicalIF":2.6,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/9f/4c/10.1177_26317745221136775.PMC9749503.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10392048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the landscape, hot topics, and trends of bariatric metabolic surgery with machine learning and bibliometric analysis.","authors":"Yancheng Song,&nbsp;Zhenni Ni,&nbsp;Yi Li,&nbsp;Zhaopeng Li,&nbsp;Jian Zhang,&nbsp;Dong Guo,&nbsp;Chentong Yuan,&nbsp;Zhuoli Zhang,&nbsp;Yu Li","doi":"10.1177/26317745221111944","DOIUrl":"https://doi.org/10.1177/26317745221111944","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to analyze the landscape of publications on bariatric metabolic surgery through machine learning and help experts and scholars from various disciplines better understand bariatric metabolic surgery's hot topics and trends.</p><p><strong>Methods: </strong>In January 2021, publications indexed in PubMed under the Medical Subject Headings (MeSH) term 'Bariatric Surgery' from 1946 to 2020 were downloaded. Python was used to extract publication dates, abstracts, and research topics from the metadata of publications for bibliometric evaluation. Descriptive statistical analysis, social network analysis (SNA), and topic modeling with latent Dirichlet allocation (LDA) were used to reveal bariatric metabolic surgery publication growth trends, landscape, and research topics.</p><p><strong>Results: </strong>A total of 21,798 records of bariatric metabolic surgery-related literature data were collected from PubMed. The number of publications indexed to bariatric metabolic surgery had expanded rapidly. <i>Obesity Surgery</i> and <i>Surgery for Obesity and Related Diseases</i> are currently the most published journals in bariatric metabolic surgery. The bariatric metabolic surgery research mainly included five topics: bariatric surgery intervention, clinical case management, basic research, body contour, and surgical risk study.</p><p><strong>Conclusion: </strong>Despite a rapid increase in bariatric metabolic surgery-related publications, few studies were still on quality of life, psychological status, and long-term follow-up. In addition, basic research has gradually increased, but the mechanism of bariatric metabolic surgery remains to be further studied. It is predicted that the above research fields may become potential hot topics in the future.</p>","PeriodicalId":40947,"journal":{"name":"Therapeutic Advances in Gastrointestinal Endoscopy","volume":"15 ","pages":"26317745221111944"},"PeriodicalIF":2.6,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/dc/f8/10.1177_26317745221111944.PMC9340401.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10502112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of radiomics in diagnosis and staging of pancreatic cancer","authors":"C. Casà, A. Piras, A. D’Aviero, F. Preziosi, S. Mariani, D. Cusumano, A. Romano, I. Boškoski, J. Lenkowicz, N. Dinapoli, F. Cellini, M. Gambacorta, V. Valentini, G. Mattiucci, Luca Boldrini","doi":"10.1177/26317745221081596","DOIUrl":"https://doi.org/10.1177/26317745221081596","url":null,"abstract":"Introduction: Pancreatic cancer (PC) is one of the most aggressive tumours, and better risk stratification among patients is required to provide tailored treatment. The meaning of radiomics and texture analysis as predictive techniques are not already systematically assessed. The aim of this study is to assess the role of radiomics in PC. Methods: A PubMed/MEDLINE and Embase systematic review was conducted to assess the role of radiomics in PC. The search strategy was ‘radiomics [All Fields] AND (“pancreas” [MeSH Terms] OR “pancreas” [All Fields] OR “pancreatic” [All Fields])’ and only original articles referred to PC in humans in the English language were considered. Results: A total of 123 studies and 183 studies were obtained using the mentioned search strategy on PubMed and Embase, respectively. After the complete selection process, a total of 56 papers were considered eligible for the analysis of the results. Radiomics methods were applied in PC for assessment technical feasibility and reproducibility aspects analysis, risk stratification, biologic or genomic status prediction and treatment response prediction. Discussion: Radiomics seems to be a promising approach to evaluate PC from diagnosis to treatment response prediction. Further and larger studies are required to confirm the role and allowed to include radiomics parameter in a comprehensive decision support system.","PeriodicalId":40947,"journal":{"name":"Therapeutic Advances in Gastrointestinal Endoscopy","volume":"15 1","pages":""},"PeriodicalIF":2.6,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45415177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endoscopic mucosal resection using a ligation device for duodenal neuroendocrine tumors: a simple method","authors":"Y. Inokuchi, K. Hayashi, Y. Kaneta, Y. Okubo, M. Watanabe, M. Furuta, N. Machida, S. Maeda","doi":"10.1177/26317745221103735","DOIUrl":"https://doi.org/10.1177/26317745221103735","url":null,"abstract":"Introduction: Duodenal neuroendocrine tumors (DNETs) smaller than 1 cm in diameter, without invasion to the muscularis propria, have a low risk of metastasis. Therefore, DNETs are frequently resected endoscopically. However, among the various procedures, the best fit for DNET in terms of feasibility, effectiveness, and simplicity is unclear. Methods: Patients with DNET who underwent endoscopic submucosal resection using a ligation device (ESMR-L) at Kanagawa Cancer Center between May 2003 and December 2020 were studied retrospectively to evaluate clinical characteristics and short-term and long-term outcomes. Results: Eleven consecutive patients with 12 lesions were treated with 12 sessions of ESMR-L. Lesions were discovered in patients at a median age of 68 (range, 50–83) years. One patient had two lesions at the time of the initial ESMR-L session. Eleven of the 12 lesions (91.7%) existed in the duodenal bulb, of which 10 (83.3%) were in the anterior wall, and the remaining one (8.3%) existed in the descending part of the duodenum. The en bloc and R0 resection rates were 100% and 75%, respectively. The rates of bleeding and perforation were both 0%. Among the four patients who had non-curative resections, two patients underwent additional surgery after ESMR-L. One patient had a local remnant tumor, and the other had lymph node metastasis. In cases of local remnant tumors, the vertical margin was positive in the ESMR-L specimen. In that case, ligation by the O-ring was insufficient, retrospectively. All patients had no recurrence during the median follow-up period of 5.7 years. Discussion: ESMR-L was the best fit for DNET within the indications for endoscopic resection. It is a simple procedure that enables easy and complete resection of DNETs without complications.","PeriodicalId":40947,"journal":{"name":"Therapeutic Advances in Gastrointestinal Endoscopy","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47908943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Safety of different electrocautery modes for endoscopic sphincterotomy: a Bayesian network meta-analysis.","authors":"Abdellah Hedjoudje,&nbsp;Chérifa Cheurfa,&nbsp;Jad Farha,&nbsp;Bénédicte Jaïs,&nbsp;Alain Aubert,&nbsp;Diane Lorenzo,&nbsp;Frédérique Maire,&nbsp;Dilhana Badurdeen,&nbsp;Vivek Kumbhari,&nbsp;Frédéric Prat","doi":"10.1177/26317745211062983","DOIUrl":"https://doi.org/10.1177/26317745211062983","url":null,"abstract":"<p><strong>Background and aims: </strong>Post-endoscopic retrograde cholangiopancreatography acute pancreatitis (PAP) and post-sphincterotomy hemorrhage are known adverse events of post-endoscopic retrograde cholangiopancreatography. Various electrosurgical currents can be used for endoscopic sphincterotomy. The extent to which this influences adverse events remains unclear. We assessed the comparative safety of different electrosurgical currents, through a Bayesian network meta-analysis of published studies merging direct and indirect comparison of trials.</p><p><strong>Methods: </strong>We performed a Bayesian random-effects network meta-analysis of randomized controlled trials that compared the safety of different electrocautery modes for endoscopic sphincterotomy.</p><p><strong>Results: </strong>Nine studies comparing four electrocautery modes (blended cut, pure cut, endocut, and pure cut followed by blended cut) with a combined enrollment of 1615 patients were included. The pooled results of the network meta-analysis did not show a significant difference in preventing post-sphincterotomy pancreatitis when comparing electrocautery modes. However, pure cut was associated with a statistically significant increased risk of bleeding compared with endocut [relative risk = 4.30; 95% confidence interval (1.53-12.87)]. On the other hand, the pooled results of the network meta-analysis showed no significant difference in prevention of bleeding when comparing blended cut <i>versus</i> endocut, pure cut followed by blended cut <i>versus</i> endocut, pure cut followed by blended cut <i>versus</i> blended cut, pure cut <i>versus</i> blended cut, and pure cut <i>versus</i> pure cut followed by blended cut. The results of rank probability found that endocut was most likely to be ranked the best.</p><p><strong>Conclusion: </strong>No electrocautery mode was superior to another with regard to preventing PAP. Endocut was superior with respect to preventing bleeding. Therefore, we suggest performing endoscopic sphincterotomy with endocut.</p>","PeriodicalId":40947,"journal":{"name":"Therapeutic Advances in Gastrointestinal Endoscopy","volume":"14 ","pages":"26317745211062983"},"PeriodicalIF":2.6,"publicationDate":"2021-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d8/d3/10.1177_26317745211062983.PMC8725216.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39905411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The evolution of endoscopic therapy for Barrett's esophagus.","authors":"Ashwinee Condon,&nbsp;V Raman Muthusamy","doi":"10.1177/26317745211051834","DOIUrl":"https://doi.org/10.1177/26317745211051834","url":null,"abstract":"<p><p>Barrett's esophagus is the condition in which a metaplastic columnar epithelium replaces the stratified squamous epithelium that normally lines the distal esophagus. The condition develops as a consequence of chronic gastroesophageal reflux disease and predisposes the patient to the development of esophageal adenocarcinoma. The diagnosis and management of Barrett's esophagus have undergone dramatic changes over the years and continue to evolve today. Endoscopic eradication therapy has revolutionized the management of dysplastic Barrett's esophagus and early esophageal adenocarcinoma by significantly reducing the morbidity and mortality associated with the prior gold standard of therapy, esophagectomy. The purpose of this review is to highlight current principles in the management and endoscopic treatment of this disease.</p>","PeriodicalId":40947,"journal":{"name":"Therapeutic Advances in Gastrointestinal Endoscopy","volume":"14 ","pages":"26317745211051834"},"PeriodicalIF":2.6,"publicationDate":"2021-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/92/36/10.1177_26317745211051834.PMC8543722.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39564552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}