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ASPET 2023 Annual Meeting Abstract - Pharmacogenomics and Translational Pharmacology最新文献

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Beta-hydroxyphosphocarnitine modifies the inflammation in rats with non-alcoholic steatohepatitis -羟磷肉碱改变非酒精性脂肪性肝炎大鼠的炎症
ASPET 2023 Annual Meeting Abstract - Pharmacogenomics and Translational Pharmacology Pub Date : 2023-05-18 DOI: 10.1124/jpet.122.170310
L. Rodríguez-Fragoso, Janet Sánchez‐Quevedo
{"title":"Beta-hydroxyphosphocarnitine modifies the inflammation in rats with non-alcoholic steatohepatitis","authors":"L. Rodríguez-Fragoso, Janet Sánchez‐Quevedo","doi":"10.1124/jpet.122.170310","DOIUrl":"https://doi.org/10.1124/jpet.122.170310","url":null,"abstract":"","PeriodicalId":406058,"journal":{"name":"ASPET 2023 Annual Meeting Abstract - Pharmacogenomics and Translational Pharmacology","volume":"21 2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126232975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Renoprotective Effects of Empagliflozin Against Experimentally Induced Renal Fibrosis In Vitro 恩格列净对体外实验性肾纤维化的保护作用
ASPET 2023 Annual Meeting Abstract - Pharmacogenomics and Translational Pharmacology Pub Date : 2023-05-18 DOI: 10.1124/jpet.122.216680
Sarah Bayne, S. Munusamy
{"title":"Renoprotective Effects of Empagliflozin Against Experimentally Induced Renal Fibrosis In Vitro","authors":"Sarah Bayne, S. Munusamy","doi":"10.1124/jpet.122.216680","DOIUrl":"https://doi.org/10.1124/jpet.122.216680","url":null,"abstract":"","PeriodicalId":406058,"journal":{"name":"ASPET 2023 Annual Meeting Abstract - Pharmacogenomics and Translational Pharmacology","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123940330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Novel Charged Sodium-Channel Blocker, Ntx-1175, Is Effective In Reducing Acute Visceral Hypersensitivity In Vivo 一种新型带电钠通道阻滞剂Ntx-1175在体内有效降低急性内脏超敏反应
ASPET 2023 Annual Meeting Abstract - Pharmacogenomics and Translational Pharmacology Pub Date : 2023-05-18 DOI: 10.1124/jpet.122.216180
Ehsan Noor-Mohammadi, C. Ligon, B. Meerveld, Naiyu Zheng, Bridget Bridget Cole, Jim Ellis, Anthony C. Johnson
{"title":"A Novel Charged Sodium-Channel Blocker, Ntx-1175, Is Effective In Reducing Acute Visceral Hypersensitivity In Vivo","authors":"Ehsan Noor-Mohammadi, C. Ligon, B. Meerveld, Naiyu Zheng, Bridget Bridget Cole, Jim Ellis, Anthony C. Johnson","doi":"10.1124/jpet.122.216180","DOIUrl":"https://doi.org/10.1124/jpet.122.216180","url":null,"abstract":"","PeriodicalId":406058,"journal":{"name":"ASPET 2023 Annual Meeting Abstract - Pharmacogenomics and Translational Pharmacology","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129376447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Social stress causes the emergence of functional Histamine H3 Receptors in urinary bladder smooth muscle 社会压力导致膀胱平滑肌出现功能性组胺H3受体
ASPET 2023 Annual Meeting Abstract - Pharmacogenomics and Translational Pharmacology Pub Date : 2023-05-18 DOI: 10.1124/jpet.122.228970
B. M. Jones, N. Tykocki, G. Mingin
{"title":"Social stress causes the emergence of functional Histamine H3 Receptors in urinary bladder smooth muscle","authors":"B. M. Jones, N. Tykocki, G. Mingin","doi":"10.1124/jpet.122.228970","DOIUrl":"https://doi.org/10.1124/jpet.122.228970","url":null,"abstract":"","PeriodicalId":406058,"journal":{"name":"ASPET 2023 Annual Meeting Abstract - Pharmacogenomics and Translational Pharmacology","volume":"57 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126279176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Safety Evaluation of p5RHH-p65 siRNA Nanoparticles in Mice with Colorectal Cancer Metastases p5RHH-p65 siRNA纳米颗粒在结直肠癌转移小鼠中的安全性评价
ASPET 2023 Annual Meeting Abstract - Pharmacogenomics and Translational Pharmacology Pub Date : 2023-05-18 DOI: 10.1124/jpet.122.548140
Jeremy Cho, Luke E. Springer, A. Akk, S. Wickline, C. Pham, H. Pan
{"title":"Safety Evaluation of p5RHH-p65 siRNA Nanoparticles in Mice with Colorectal Cancer Metastases","authors":"Jeremy Cho, Luke E. Springer, A. Akk, S. Wickline, C. Pham, H. Pan","doi":"10.1124/jpet.122.548140","DOIUrl":"https://doi.org/10.1124/jpet.122.548140","url":null,"abstract":"","PeriodicalId":406058,"journal":{"name":"ASPET 2023 Annual Meeting Abstract - Pharmacogenomics and Translational Pharmacology","volume":"53 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122642632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnostic and predictive value of circulating microRNAs and their regulation of BDNF signaling pathway in stroke patients 循环microrna及其对脑卒中患者BDNF信号通路的调节的诊断和预测价值
ASPET 2023 Annual Meeting Abstract - Pharmacogenomics and Translational Pharmacology Pub Date : 2023-05-18 DOI: 10.1124/jpet.122.139360
M. Marszałek, D. Keshwani, C. Eyileten, Z. Wicik, A. Nowak, S. Rosa, D. Mirowska-Guzel, A. Członkowska, G. Paré, M. Postuła
{"title":"Diagnostic and predictive value of circulating microRNAs and their regulation of BDNF signaling pathway in stroke patients","authors":"M. Marszałek, D. Keshwani, C. Eyileten, Z. Wicik, A. Nowak, S. Rosa, D. Mirowska-Guzel, A. Członkowska, G. Paré, M. Postuła","doi":"10.1124/jpet.122.139360","DOIUrl":"https://doi.org/10.1124/jpet.122.139360","url":null,"abstract":"","PeriodicalId":406058,"journal":{"name":"ASPET 2023 Annual Meeting Abstract - Pharmacogenomics and Translational Pharmacology","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131171253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Amlodipine use in Mild Cognitive Impairment reduces the risk of incident dementia in National Alzheimer’s Coordinating Center participants aged ≥55 years from 2014-2019 2014-2019年，在国家阿尔茨海默病协调中心年龄≥55岁的参与者中，轻度认知障碍患者使用氨氯地平可降低发生痴呆的风险
ASPET 2023 Annual Meeting Abstract - Pharmacogenomics and Translational Pharmacology Pub Date : 2023-05-18 DOI: 10.1124/jpet.122.552170
Karin E. Sandoval
{"title":"Amlodipine use in Mild Cognitive Impairment reduces the risk of incident dementia in National Alzheimer’s Coordinating Center participants aged ≥55 years from 2014-2019","authors":"Karin E. Sandoval","doi":"10.1124/jpet.122.552170","DOIUrl":"https://doi.org/10.1124/jpet.122.552170","url":null,"abstract":"","PeriodicalId":406058,"journal":{"name":"ASPET 2023 Annual Meeting Abstract - Pharmacogenomics and Translational Pharmacology","volume":"126 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131444960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antithrombotic Therapy Optimization in a Quaternary Care Center Anticoagulation Clinic in the Middle East 中东地区一家四级护理中心抗凝诊所的抗血栓治疗优化
ASPET 2023 Annual Meeting Abstract - Pharmacogenomics and Translational Pharmacology Pub Date : 2023-05-18 DOI: 10.1124/jpet.122.191190
Emna Abidi, P. Bon, Ramzi Khaddage, A. Cherfan, Mohammad. Kolailat, Z. Sadik, B. Atallah
{"title":"Antithrombotic Therapy Optimization in a Quaternary Care Center Anticoagulation Clinic in the Middle East","authors":"Emna Abidi, P. Bon, Ramzi Khaddage, A. Cherfan, Mohammad. Kolailat, Z. Sadik, B. Atallah","doi":"10.1124/jpet.122.191190","DOIUrl":"https://doi.org/10.1124/jpet.122.191190","url":null,"abstract":"","PeriodicalId":406058,"journal":{"name":"ASPET 2023 Annual Meeting Abstract - Pharmacogenomics and Translational Pharmacology","volume":"54 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133439605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
ATI-450: A Novel MK2 Pathway Inhibitor - Preclinical & Clinical Translational Studies to Predict Human Dose ATI-450:一种新型MK2通路抑制剂-临床前和临床转化研究预测人体剂量
ASPET 2023 Annual Meeting Abstract - Pharmacogenomics and Translational Pharmacology Pub Date : 2023-05-18 DOI: 10.1124/jpet.122.541040
H. Hope, S. Hockerman, Matthew J. Saabye, L. Stillwell, Rakesh H. Basavalingappa, Catherine Emanual, S. Mnich, Madison C. Bangs, Emma E. Huff, Aparna Kaul, A. Hildebrand, M. Cardillo, A. Aggarwal, Joseph B. Monahan
{"title":"ATI-450: A Novel MK2 Pathway Inhibitor - Preclinical & Clinical Translational Studies to Predict Human Dose","authors":"H. Hope, S. Hockerman, Matthew J. Saabye, L. Stillwell, Rakesh H. Basavalingappa, Catherine Emanual, S. Mnich, Madison C. Bangs, Emma E. Huff, Aparna Kaul, A. Hildebrand, M. Cardillo, A. Aggarwal, Joseph B. Monahan","doi":"10.1124/jpet.122.541040","DOIUrl":"https://doi.org/10.1124/jpet.122.541040","url":null,"abstract":",","PeriodicalId":406058,"journal":{"name":"ASPET 2023 Annual Meeting Abstract - Pharmacogenomics and Translational Pharmacology","volume":"54 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123525120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Phenylacetylglutamine causes a pathologic inflammation state through the ß2-adrenergic receptor /cAMP/PKA/NF-κB pathway in diabetes 苯乙酰谷氨酰胺在糖尿病中通过ß2-肾上腺素能受体/cAMP/PKA/NF-κB通路引起病理性炎症状态
ASPET 2023 Annual Meeting Abstract - Pharmacogenomics and Translational Pharmacology Pub Date : 2023-05-18 DOI: 10.1124/jpet.122.549610
Lu Huang
{"title":"Phenylacetylglutamine causes a pathologic inflammation state through the ß2-adrenergic receptor /cAMP/PKA/NF-κB pathway in diabetes","authors":"Lu Huang","doi":"10.1124/jpet.122.549610","DOIUrl":"https://doi.org/10.1124/jpet.122.549610","url":null,"abstract":"","PeriodicalId":406058,"journal":{"name":"ASPET 2023 Annual Meeting Abstract - Pharmacogenomics and Translational Pharmacology","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131408931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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