Frontiers in Audiology and Otology最新文献_第2页

COVID-19 and hearing loss—A narrative review 2019冠状病毒病与听力损失——述评

Frontiers in Audiology and Otology Pub Date : 2023-08-11 DOI: 10.3389/fauot.2023.1233793

Sharon J Feng, François Voruz, Michelle Yu, Anil K. Lalwani

{"title":"COVID-19 and hearing loss—A narrative review","authors":"Sharon J Feng, François Voruz, Michelle Yu, Anil K. Lalwani","doi":"10.3389/fauot.2023.1233793","DOIUrl":"https://doi.org/10.3389/fauot.2023.1233793","url":null,"abstract":"Interest in hearing loss associated with COVID-19 has increased since the pandemic started. Early on during the spread of SARS-CoV-2 across the globe, reports of smell and taste disorders secondary to COVID-19 emerged, and to a lesser extent, reports of sensorineural hearing loss also surfaced. This raised questions regarding changes in the epidemiology of hearing loss and modifications to otologic practice that have evolved in response to the COVID-19 pandemic. To elucidate these questions, we performed a comprehensive literature search, including articles up to November 2022, using “COVID hearing loss” in MEDLINE. A total of 153 articles were included for full-text review and data extraction. There are several proposed mechanisms through which COVID-19 may contribute to hearing loss—direct viral infection, microthrombi, or hemorrhage. There is a growing repository of case reports and series on SARS-CoV-2-associated sensorineural hearing loss, with variable quality. Most patients who experienced hearing loss did so within a month of infection, with most patients' symptoms resolving within 2 weeks. The growing body of literature discussing SARS-CoV-2-associated hearing loss does not suggest a significant rise in the occurrence of sensorineural or overall hearing loss. In this ongoing COVID-19 era, hearing loss should be approached in the same state-of-the-art manner as before the pandemic.","PeriodicalId":404946,"journal":{"name":"Frontiers in Audiology and Otology","volume":"78 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131391536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hearing aids with tinnitus sound support reduce tinnitus severity for new and experienced hearing aid users 助听器与耳鸣声音支持减少耳鸣严重程度为新的和有经验的助听器用户

Frontiers in Audiology and Otology Pub Date : 2023-08-04 DOI: 10.3389/fauot.2023.1238164

Philip J. Sanders, Reena M. Nielsen, J. J. Jensen, G. Searchfield

{"title":"Hearing aids with tinnitus sound support reduce tinnitus severity for new and experienced hearing aid users","authors":"Philip J. Sanders, Reena M. Nielsen, J. J. Jensen, G. Searchfield","doi":"10.3389/fauot.2023.1238164","DOIUrl":"https://doi.org/10.3389/fauot.2023.1238164","url":null,"abstract":"This interventional study tested the hypothesis that hearing aids with a tinnitus sound support feature would reduce the impact of tinnitus for both new and experienced hearing aid users over a 12-week trial period.A total of 19 experienced hearing aid users and 21 participants with no previous hearing aid experience completed the study. Hearing aids were fitted and dispensed with tinnitus masking sounds adjusted to individual preferences. The primary outcome measure was the Tinnitus Functional Index (TFI) score change between baseline and the end of the 12-week trial. This trial was registered on the Australian New Zealand Clinical Trials Registry, trial ID: ACTRN12621001754831.The TFI scores and secondary measures indicated significant improvements (reductions in tinnitus impact) at the end of the trial compared to the baseline for both experienced and new hearing aid users. Since no group differences were observed, pooled data are presented in this study. The median TFI total score before treatment was 49.0 (IQR = 40.0), and the median TFI total score after treatment was 26.0 (IQR = 26.0). A significant reduction (p = 0.0001) in the total TFI score of 24 points was observed after treatment, producing a large effect size (d = 0.60).The results confirm previous findings that hearing aids assist in reducing the impact of tinnitus on daily life. The Oticon miniRITE R combination hearing aids used in this study resulted in similar improvements for both new and existing hearing aid users. This suggests that the tinnitus-reducing effects of these aids were greater than those already being used by participants.","PeriodicalId":404946,"journal":{"name":"Frontiers in Audiology and Otology","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131153404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Subclinical hearing loss and educational performance in children: a national study 儿童亚临床听力损失与教育表现:一项全国性研究

Frontiers in Audiology and Otology Pub Date : 2023-08-03 DOI: 10.3389/fauot.2023.1214188

Rahul K. Sharma, Alexander Chern, Justin S. Golub, A. Lalwani

{"title":"Subclinical hearing loss and educational performance in children: a national study","authors":"Rahul K. Sharma, Alexander Chern, Justin S. Golub, A. Lalwani","doi":"10.3389/fauot.2023.1214188","DOIUrl":"https://doi.org/10.3389/fauot.2023.1214188","url":null,"abstract":"Hearing loss can cause speech and language delays, communication barriers, and learning problems. Such factors are associated with reduced academic achievement, social isolation, decreased quality of life, and poorer health outcomes. We use a national cohort of children to examine how subclinical hearing loss is associated with academic/educational performance. The goal of this study is to determine if different levels of subclinical hearing loss (pure tone average ≤ 25 dB HL) are associated with educational testing outcomes in children.Analysis of children 6–16 years old who participated in the National Health and Nutrition Examination Survey (NHANES-III, 1988–1994) was performed. Air-conduction thresholds were measured at 0.5, 1, 2, 4, 6, and 8 kHz. A four-frequency pure-tone average (PTA) was calculated from 0.5, 1, 2, and 4 kHz. Hearing thresholds were divided into categories ( ≤ 0, 1–10, and 11–25 dB) for analysis. The outcomes of interest were the Wide Range Achievement Test (WRAT-R) and Wechsler Intelligence Scale for Children (WISC-R). Analysis was conducted using ANOVA and logistic regression.We analyzed 3,965 participants. In univariable analysis, the average scores in scaled math, reading, digit span (short-term memory), and block design (visual-motor skills) were significantly lower with worsening hearing categories (p < 0.01). In multivariable regression PTAs of 1–10 dB HL (OR 1.72, 95% CI 1.29–2.29, p < 0.01) and 11-25 dB HL (OR: 2.99, 95% CI 1.3–6.65, p < 0.01), compared to PTA of ≤0 dB HL, were associated with poor reading test performance (<25th percentile).Subclinical hearing loss is associated with worse performance on educational attainment (as measured by reading test performance) in children between the ages of 6–16.","PeriodicalId":404946,"journal":{"name":"Frontiers in Audiology and Otology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130021928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Using machine learning to assist auditory processing evaluation 利用机器学习辅助听觉处理评价

Frontiers in Audiology and Otology Pub Date : 2023-07-21 DOI: 10.3389/fauot.2023.1215965

Hasitha Wimalarathna, Sangamanatha Ankmnal-Veeranna, Minh Duong, Chris Allan, S. Agrawal, P. Allen, J. Samarabandu, H. Ladak

{"title":"Using machine learning to assist auditory processing evaluation","authors":"Hasitha Wimalarathna, Sangamanatha Ankmnal-Veeranna, Minh Duong, Chris Allan, S. Agrawal, P. Allen, J. Samarabandu, H. Ladak","doi":"10.3389/fauot.2023.1215965","DOIUrl":"https://doi.org/10.3389/fauot.2023.1215965","url":null,"abstract":"Approximately 0.2–5% of school-age children complain of listening difficulties in the absence of hearing loss. These children are often referred to an audiologist for an auditory processing disorder (APD) assessment. Adequate experience and training is necessary to arrive at an accurate diagnosis due to the heterogeneity of the disorder.The main goal of the study was to determine if machine learning (ML) can be used to analyze data from the APD clinical test battery to accurately categorize children with suspected APD into clinical sub-groups, similar to expert labels.The study retrospectively collected data from 134 children referred for ADP assessment from 2015 to 2021. Labels were provided by expert audiologists for training ML models and derived features from clinical assessments. Two ensemble learning techniques, Random Forest (RF) and Xgboost, were employed, and Shapley Additive Explanations (SHAP) were used to understand the contribution of each derived feature on the model's prediction.The RF model was found to have higher accuracy (90%) than the Xgboost model for this dataset. The study found that features derived from behavioral tests performed better compared to physiological test features, as shown by the SHAP.The study aimed to use machine learning (ML) algorithms to reduce subjectivity in audiological assessments used to diagnose APD in children and identify sub-groups in the clinical population for selective interventions.The study suggests that this work may facilitate the future development of APD clinical diagnosis software.","PeriodicalId":404946,"journal":{"name":"Frontiers in Audiology and Otology","volume":"48 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127536241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A holistic perspective on hearing loss: first quality-of-life questionnaire (HL-QOL) for people with hearing loss based on the international classification of functioning, disability, and health 听力损失的整体视角:基于国际功能、残疾和健康分类的听力损失人群的首次生活质量问卷(HL-QOL

Frontiers in Audiology and Otology Pub Date : 2023-06-22 DOI: 10.3389/fauot.2023.1207220

A. Illg, Edda Amann, K. Koinig, I. Anderson, T. Lenarz, Mareike Billinger-Finke

{"title":"A holistic perspective on hearing loss: first quality-of-life questionnaire (HL-QOL) for people with hearing loss based on the international classification of functioning, disability, and health","authors":"A. Illg, Edda Amann, K. Koinig, I. Anderson, T. Lenarz, Mareike Billinger-Finke","doi":"10.3389/fauot.2023.1207220","DOIUrl":"https://doi.org/10.3389/fauot.2023.1207220","url":null,"abstract":"To date, there is no quality-of-life questionnaire for people with hearing loss based on a multidisciplinary framework. Therefore, this study aimed to develop and validate a comprehensive assessment tool that addresses quality of life in people with hearing loss who use a cochlear implant based on the International Classification of Functioning, Disability, and Health (ICF).In a first step, the Quality of Life in People with Hearing Loss Questionnaire (HL-QoL) was developed and tested for face validity. In a second step, the HL-QoL was evaluated and validated. In a third step, the HL-QoL was finalized based on the outcomes of the evaluation and validation.Eighty-four study participants fully completed the HL-QoL. The result of the test-retest reliability analysis was high and highly significant (n = 63; r = 0.914; p < 0.001). The mean total HL-QoL score (100.7 ± SD 24.58) suggests an overall high level of quality-of-life in this sample of people with hearing loss using a cochlear implant. The final version of the HL-QoL contains 21 items.The HL-QoL has shown to be a valid and reliable tool to assess quality of life in people with hearing loss who use a cochlear implant. In addition to the total score, it is possible to calculate subscales based on the ICF components Body Functions and Activities and Participation.","PeriodicalId":404946,"journal":{"name":"Frontiers in Audiology and Otology","volume":"94 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131284358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Single-cell sequencing: a powerful technique to understand the pathophysiology of auditory disorders 单细胞测序:一种了解听觉障碍病理生理学的强大技术

Frontiers in Audiology and Otology Pub Date : 2023-06-15 DOI: 10.3389/fauot.2023.1191143

Maria-Pia Tuset, Matthew D Wiefels, Keelin McKenna, Jeenu Mittal, Chirag Gowda, Rahul Mittal, A. Eshraghi

{"title":"Single-cell sequencing: a powerful technique to understand the pathophysiology of auditory disorders","authors":"Maria-Pia Tuset, Matthew D Wiefels, Keelin McKenna, Jeenu Mittal, Chirag Gowda, Rahul Mittal, A. Eshraghi","doi":"10.3389/fauot.2023.1191143","DOIUrl":"https://doi.org/10.3389/fauot.2023.1191143","url":null,"abstract":"Deciphering the inner ear transcriptome has allowed major breakthroughs in therapeutic development for auditory disorders. Single-cell sequencing (SCS) technologies, through the analysis of cellular heterogeneity and the identification of novel gene markers, can significantly enhance our understanding about auditory disorders. The application of SCS has allowed the identification of gene targets specific to the inner ear cellular subtypes such as supporting cells, hair cells, stria vascularis cells, and spiral ganglion neuron cells. SCS has provided new insights into the molecular mechanisms underlying the pathophysiology of auditory disorders such as noise-trauma induced hearing loss, ototoxicity, sudden sensorineural hearing loss (SSNHL), vestibular schwannomas and acute otitis media, leading to the discovery of novel therapeutic targets. The objective of this perspective article is to discuss recent advancements regarding the utilization of SCS for inner ear research. With global initiatives striving to overcome the increasing burden of hearing loss, the SCS technique holds a great potential in revolutionizing the management of auditory disorders, paving the way to develop effective treatment modalities.","PeriodicalId":404946,"journal":{"name":"Frontiers in Audiology and Otology","volume":"2003 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125770993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The role of hearing professionals for over-the-counter hearing aids 听力专业人员在非处方助听器中的作用

Frontiers in Audiology and Otology Pub Date : 2023-04-25 DOI: 10.3389/fauot.2023.1167853

Carlos A. Perez-Heydrich, Colleen Zenczak, Lindsey Roque, Colleen Ryan, Y. Agrawal, Zahra N. Sayyid

{"title":"The role of hearing professionals for over-the-counter hearing aids","authors":"Carlos A. Perez-Heydrich, Colleen Zenczak, Lindsey Roque, Colleen Ryan, Y. Agrawal, Zahra N. Sayyid","doi":"10.3389/fauot.2023.1167853","DOIUrl":"https://doi.org/10.3389/fauot.2023.1167853","url":null,"abstract":"Adults with all levels of hearing loss have faced financial and accessibility constraints in obtaining prescription hearing aids. To increase access to hearing aids, the Food and Drug Administration (FDA) has created a new designation of over-the-counter (OTC) hearing aids for adults with perceived mild to moderate hearing loss. The goal of this article is to describe the incorporation of OTC hearing aid users into established audiology services. A proposed workflow was created by otolaryngologists and audiologists at Johns Hopkins University School of Medicine and is being implemented at outpatient audiology offices. We used published criteria for appropriate OTC hearing aid usage and disqualifying criteria hearing specialists should be aware of. The proposed workflow describes the multiple entry points for OTC hearing aid users seeking access to care and appropriate objectives for these visits. The new FDA ruling has increased the accessibility of hearing assistance devices; however, the varying degrees of retailer support systems could lead to improper fitting and other technical problems for some patients trialing new hearing aids. Our proposed workflow aims to describe the incorporation of established hearing assistance services with the new OTC hearing aid market.","PeriodicalId":404946,"journal":{"name":"Frontiers in Audiology and Otology","volume":"68 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126310647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Specialty grand challenge: Smarter solutions for tinnitus 专业大挑战:耳鸣更智能的解决方案

Frontiers in Audiology and Otology Pub Date : 2023-02-02 DOI: 10.3389/fauot.2023.1101233

G. Searchfield

引用次数: 0

Responsiveness of the electrically stimulated cochlear nerve in patients with a missense variant in ACTG1: Preliminary Results ACTG1错义变异患者电刺激耳蜗神经的反应性:初步结果

Frontiers in Audiology and Otology Pub Date : 2022-10-26 DOI: 10.1101/2022.10.24.22281451

Y. Yuan, D. Yan, J. Skidmore, P. Chapagain, X. Liu, S. He

{"title":"Responsiveness of the electrically stimulated cochlear nerve in patients with a missense variant in ACTG1: Preliminary Results","authors":"Y. Yuan, D. Yan, J. Skidmore, P. Chapagain, X. Liu, S. He","doi":"10.1101/2022.10.24.22281451","DOIUrl":"https://doi.org/10.1101/2022.10.24.22281451","url":null,"abstract":"Objectives: This preliminary study identified a missense variant in ACTG1 (NM_001614.5) in a family with autosomal dominant non-syndromic hearing loss (ADNSHL). The responsiveness of the electrically-stimulated cochlear nerve (CN) in two implanted participants with this missense change was also evaluated and reported. Design: Genetic testing was done using a custom capture panel (MiamiOtoGenes) and whole exome sequencing. The responsiveness of the electrically-stimulated CN was evaluated in two members of this family (G1 and G4) using the electrically evoked compound action potential (eCAP). eCAP results from these two participants were compared with those measured three implanted patient populations: children with cochlear nerve deficiency, children with idiopathic hearing loss and normal-sized cochlear nerves, and postligually deafened adults. Results: Sequencing of ACTG1 identified a missense c.737A>T (p. Gln246Leu) variant in ACTG1 (NM_001614.5) which is most likely the genetic cause of ADNSHL in this family. eCAP results measured in these two participants showed substantial variations. Conclusion: The missense c.737A>T (p. Gln246Leu) variant in ACTG1 (NM_001614.5) co-segregated with hearing loss in this family. The responsiveness of the electrically-stimulated CN can vary among patients with the same genetic variants, which suggests the importance of evaluating the functional status of the CN for individual CI patients.","PeriodicalId":404946,"journal":{"name":"Frontiers in Audiology and Otology","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133933033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0