Neurosonology and Cerebral Hemodynamics最新文献_第2页

Timing of Valsalva maneuver and contrast injection for detecting patent foramen ovale on transesophageal echocardiography 经食管超声心动图检测卵圆孔未闭的Valsalva手法和造影剂注射时机

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Neurosonology and Cerebral Hemodynamics Pub Date : 2022-04-30 DOI: 10.2301/neurosonology.35.4

Y. Terasawa, Kenichiro Sakai, Ayumi Arai, T. Komatsu, Hidetaka Mitsumura, Y. Iguchi

{"title":"Timing of Valsalva maneuver and contrast injection for detecting patent foramen ovale on transesophageal echocardiography","authors":"Y. Terasawa, Kenichiro Sakai, Ayumi Arai, T. Komatsu, Hidetaka Mitsumura, Y. Iguchi","doi":"10.2301/neurosonology.35.4","DOIUrl":"https://doi.org/10.2301/neurosonology.35.4","url":null,"abstract":"Background and purpose : For investigating right-to-left shunt with transcranial Doppler, the Valsalva maneuver (VM) is recommended to be commenced five seconds after injection of contrast agent. When using transesophageal echocardiography (TEE) for detection of patent foramen ovale (PFO), VM is recommended to be commenced before injection. The aim of this study is to clarify the detection rates of PFO with TEE conducted with different VM timings. Methods : We enrolled patients who underwent TEE for detecting PFO. We performed VM four times with contrast agent (CA), twice with VM performed prior to CA injection (PreInj-VC) and twice with VM performed after CA injection (PostInj-VC). We diagnosed the presence of PFO and classified as follows: non-PFO, small-PFO (< 30 bubbles), large-PFO (≥ 30 bubbles). We calculated the concordance rate of diagnosis for PFO between PreInj-VC and PostInj-VC. Results : Of 79 patients (median age 66 years, male 68%), 30 patients (38%) had PFO (10 patients, large PFO; 20 patients, small PFO). PFO was identified in 27 patients on PreInj-VC and in 28 on PostInj-VC. Diagnostic agreement between PreInj-VC and PostInj-VC was found in 71 patients (90%). Regarding the PFO size, the concordance rate for large PFO was 96% ( κ = 0.82, p < 0.001) and that for small PFO was 92% ( κ = 0.80, p < 0.001). Conclusion : Diagnostic agreement of the deference timings of VM, such as PreInj-VC and PostInj-VC, was as high as 90%. Moreover, two timings of VM made diagnosis of PFO more accurate.","PeriodicalId":40206,"journal":{"name":"Neurosonology and Cerebral Hemodynamics","volume":"26 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2022-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88485477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Cholesterol crystal embolism and systemic vascular evaluation with ultrasonography: a case report 胆固醇结晶栓塞及全身血管超声评价1例

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Neurosonology and Cerebral Hemodynamics Pub Date : 2022-01-01 DOI: 10.2301/neurosonology.35.39

Muneaki Kikuno, Kanta Tanaka, K. Hatakeyama, M. Koga

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A case of maximum peak systolic velocity in the distal part of internal carotid stenosis 颈内动脉远端狭窄处最大收缩速度峰值1例

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Neurosonology and Cerebral Hemodynamics Pub Date : 2022-01-01 DOI: 10.2301/neurosonology.35.101

Eriko Yamaguchi, Kozue Saito, S. Yoshimura, M. Koga

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A case of femoral pseudoaneurysm without inguinal mass or pain after femoral artery puncture 股动脉穿刺后无腹股沟肿块及疼痛的股假性动脉瘤1例

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Neurosonology and Cerebral Hemodynamics Pub Date : 2022-01-01 DOI: 10.2301/neurosonology.35.110

Yohei Shibata, Masahiro Uchimura, Kazuyuki Mikami, Mizuki Kambara, Tsutomu Yoshikane, Shinya Hagiwara, H. Nagai, Kentaro Hayashi, Y. Akiyama

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Abstracts of the 41st Annual Meeting of the Japan Academy of Neurosonology & Embolus 2022 日本神经声学与栓子学会第41届年会摘要

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Neurosonology and Cerebral Hemodynamics Pub Date : 2022-01-01 DOI: 10.2301/neurosonology.35.45

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Peak systolic velocity of carotid artery disease could reflect the pathophysiology of atherothrombotic brain infarction 颈动脉病变的收缩峰值速度可以反映动脉粥样硬化性血栓性脑梗死的病理生理

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Neurosonology and Cerebral Hemodynamics Pub Date : 2022-01-01 DOI: 10.2301/neurosonology.35.104

H. Sadahiro, K. Sugimoto, F. Oka, M. Shimokawa, H. Ishihara

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Three cases with cardioembolic stroke after left atrial appendage occlusion 左心耳闭塞后心栓塞性脑卒中3例

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Neurosonology and Cerebral Hemodynamics Pub Date : 2021-01-01 DOI: 10.2301/NEUROSONOLOGY.34.10

Ai Keito, Y. Terasawa, Yoshinori Miyamoto, A. Nakamichi, T. Himeno, Shuzo Shinozuka, T. Kohriyama

{"title":"Three cases with cardioembolic stroke after left atrial appendage occlusion","authors":"Ai Keito, Y. Terasawa, Yoshinori Miyamoto, A. Nakamichi, T. Himeno, Shuzo Shinozuka, T. Kohriyama","doi":"10.2301/NEUROSONOLOGY.34.10","DOIUrl":"https://doi.org/10.2301/NEUROSONOLOGY.34.10","url":null,"abstract":"We reported three cases with cardioembolic stroke after left atrial appendage (LAA) occlusion. First case is 72 years old man with right hemiparesis. His MRI showed acute ischemic lesion in left MCA territory. He was performed endovascular treatment and got complete recanalization. He had a history of his mitral valve replacement and LAA occlusion due to his atrial fibrillation and mitral valve regurgitation. His transesophageal echocardiography (TEE) pointed out fistula between left atrium (LA) and LAA. The second case is 74 years old man who got operation of LAA closure 6 years ago. He suffered from right hemiparesis caused by his MCA M2 occlusion. We examined TEE and found a fistula between LA and LAA. The third case is 72 years old man with right thalamus infarction. TEE showed the very small fistula between LA and LAA detected only by Doppler color flow imaging. It has been reported that subsequent LAA closure associated with cardiac surgery reduces the incidence of stroke. However, incomplete LAA closure was known as cause of stroke. Therefore, we considered it is necessary to perform TEE to observe LAA on the TEE even after LAA closure.","PeriodicalId":40206,"journal":{"name":"Neurosonology and Cerebral Hemodynamics","volume":"21 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78040647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Research on gene therapy using ultrasound and nanobubbles 超声与纳米气泡基因治疗的研究

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Neurosonology and Cerebral Hemodynamics Pub Date : 2021-01-01 DOI: 10.2301/neurosonology.34.77

Hiroshi Kida, K. Tachibana

{"title":"Research on gene therapy using ultrasound and nanobubbles","authors":"Hiroshi Kida, K. Tachibana","doi":"10.2301/neurosonology.34.77","DOIUrl":"https://doi.org/10.2301/neurosonology.34.77","url":null,"abstract":"超音波穿孔法(ソノポレーション)は電気穿孔法(エレクトロポレーション)と比較して生体組織への侵襲の少ない,安全な物理的な薬物送達システム(drug delivery system:DDS)である .時間的,空間的な制御に優れ,超音波の照射部位は体外からミリメートル単位で精密に制御することが可能である. 超音波照射によって,一時的に細胞膜を穿孔し,薬物や遺伝子を細胞質内に送達する方法がソノポレーションである .その機序において音響キャビテーション現象が重要な役割を担っていることが明らかになっている. 超音波を液体に向けて照射すると音圧により,音場では周波数に同期して低圧と高圧状態が繰り返される.液体の圧力が飽和蒸気圧以下となった瞬間に気体分子を核として発泡する.低圧と高圧の繰り返しにより,気泡は膨張収縮(オシレーション)しながら成長し,最終的には破裂崩壊する.この一連の流れが音響キャビテーションである .気泡の崩壊時に発生する強い衝撃により,その周囲にはマイクロ液体ジェット流が生じる.これにより細胞膜が穿孔され,薬物や遺伝子の細胞内送達が実現される. バブル製剤をあらかじめ液体中に添加し,超音波照射時のキャビテーション核として機能させることにより, その閾値を低下させ,ソノポレーションの効果を著しく増強させることが可能である.これまで薬物や遺伝子送達の試みに用いられてきたさまざまなバブル製剤は直径 1~ 1,000μmのマイクロバブルが主であった.近年ではそれよりもさらに小さい,直径 1~ 1,000nmのナノバブルを用いた研究が進みつつある.マイクロバブルと比較して,ナノバブルは生体組織のより深部に到達可能で ,浮上速度がきわめて遅く,長期間の滞留性を示す 5) などの特徴をもつ. 超音波遺伝子導入法の実際","PeriodicalId":40206,"journal":{"name":"Neurosonology and Cerebral Hemodynamics","volume":"96 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77017036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Usefulness of transoral carotid ultrasonography: a case report on stenting for internal carotid artery dissection 经口颈动脉超声检查在颈内动脉夹层支架置入术中的应用

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Neurosonology and Cerebral Hemodynamics Pub Date : 2021-01-01 DOI: 10.2301/neurosonology.34.83

Naoya Yamazaki, R. Doijiri, Kohei Takikawa, Takuji Sonoda, Mitsunobu Sato, Michiko Yokosawa, T. Sugawara, Takahiko Kikuchi, Naoto Kimura

{"title":"Usefulness of transoral carotid ultrasonography: a case report on stenting for internal carotid artery dissection","authors":"Naoya Yamazaki, R. Doijiri, Kohei Takikawa, Takuji Sonoda, Mitsunobu Sato, Michiko Yokosawa, T. Sugawara, Takahiko Kikuchi, Naoto Kimura","doi":"10.2301/neurosonology.34.83","DOIUrl":"https://doi.org/10.2301/neurosonology.34.83","url":null,"abstract":"経口腔頸動脈超音波検査(transoral carotid ultrasonography:TOCU)は 1998年に Yasakaらにより提唱された手法で,リニアプローブによる頸部エコー検査で観察可能な範囲よりも高位の頭蓋外内頸動脈を評価することが可能である .しかし経腟プローブは汎用性に欠け, 臨床の現場において十分普及しておらず,マイクロコンベックスプローブ(micro-convex probe:MCP)を使用した TOCUの変法(modified transoral carotid ultrasonography:mTOCU)が報告されている. 今回われわれは,特発性頸部内頸動脈解離に対して頭蓋内ステントを用いて血行再建術を行い,mTOCUを用いてステント内腔を評価し得た 1例を経験したので報告する. 本症例で使用した脳動脈瘤コイル塞栓補助ステント (Enterprise 2,Johnson & Johnson Codman, Miami, FL, USA)は保険適用外使用であり,われわれの施設では臨床倫理委員会の承認を得て使用した(承認 No. 370). また本症例報告に関しては患者の同意を得ている. 特発性頸部内頸動脈解離に対する血行再建術後に経口腔頸動脈超音波検査でステントを評価し得た 1例","PeriodicalId":40206,"journal":{"name":"Neurosonology and Cerebral Hemodynamics","volume":"29 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73559678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Knowledge of “artifact” not to fall into a “pitfall” “工件”的知识不会落入“陷阱”

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Neurosonology and Cerebral Hemodynamics Pub Date : 2021-01-01 DOI: 10.2301/NEUROSONOLOGY.34.1

Atsuko Kawano, Asami Maruyama, Kota Ichihashi

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