International Journal of Biological and Pharmaceutical Sciences Archive最新文献_第2页

Ethical considerations in implementing generative AI for healthcare supply chain optimization: A cross-country analysis across India, the United Kingdom, and the United States of America 实施生成式人工智能优化医疗保健供应链的伦理考虑因素：印度、英国和美国的跨国分析

International Journal of Biological and Pharmaceutical Sciences Archive Pub Date : 2024-02-28 DOI: 10.53771/ijbpsa.2024.7.1.0015

Amina Catherine Ijiga, Ehi Peace, Idoko Peter Idoko, Daniel Obekpa Agbo, Kimberly D. Harry, Chijioke Ifakandu Ezebuka, Esther Ene Umama

{"title":"Ethical considerations in implementing generative AI for healthcare supply chain optimization: A cross-country analysis across India, the United Kingdom, and the United States of America","authors":"Amina Catherine Ijiga, Ehi Peace, Idoko Peter Idoko, Daniel Obekpa Agbo, Kimberly D. Harry, Chijioke Ifakandu Ezebuka, Esther Ene Umama","doi":"10.53771/ijbpsa.2024.7.1.0015","DOIUrl":"https://doi.org/10.53771/ijbpsa.2024.7.1.0015","url":null,"abstract":"This review paper critically examines the ethical considerations involved in implementing generative Artificial Intelligence (AI) in healthcare supply chain optimization across three distinct regions: India, the United Kingdom, and the United States of America. The study synthesizes findings from various case studies and academic research to highlight both common and unique ethical challenges faced in these countries. Key themes such as data privacy, algorithmic transparency, and equitable access to AI-driven healthcare solutions are explored, alongside the unique socio-cultural, legal, and regulatory challenges specific to each region. The paper proposes a set of best practices for incorporating ethical considerations into the deployment of generative AI in healthcare. These include the development of inclusive ethical frameworks, regular ethical audits, comprehensive training and education programs, public engagement initiatives, and interdisciplinary collaboration. The paper also delves into future research directions and policy development, emphasizing the need to address healthcare disparities, adapt legal and regulatory frameworks, enhance generative AI explainability, and evaluate long-term outcomes.The study concludes by underscoring the importance of ethical design and deployment of generative AI systems in healthcare, advocating for a balanced approach that aligns technological advancements with ethical standards and global healthcare needs. This comprehensive review aims to contribute to the discourse on ethical generative AI implementation, offering insights and recommendations for policymakers, healthcare professionals, and generative AI developers to foster responsible and beneficial use of generative AI in healthcare globally.","PeriodicalId":400966,"journal":{"name":"International Journal of Biological and Pharmaceutical Sciences Archive","volume":"22 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140420322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

In vitro regeneration of exotic fruit dragon (Hylocereus undatus) from stem fraction 外来果龙（Hylocereus undatus）的离体再生茎干部分

International Journal of Biological and Pharmaceutical Sciences Archive Pub Date : 2024-02-28 DOI: 10.53771/ijbpsa.2024.7.1.0018

M.H. Kabir, Md. Monirul Islam, Pronabananda Das, ANK Mamun

{"title":"In vitro regeneration of exotic fruit dragon (Hylocereus undatus) from stem fraction","authors":"M.H. Kabir, Md. Monirul Islam, Pronabananda Das, ANK Mamun","doi":"10.53771/ijbpsa.2024.7.1.0018","DOIUrl":"https://doi.org/10.53771/ijbpsa.2024.7.1.0018","url":null,"abstract":"Hylocereus undatus, commonly known as dragon fruit, is one of the most popular exotic fruits due to its high quality and market value. This fruit is facing different constraints, such as loss of seed viability and various diseases that affect production because the seed and cutting methods are followed to create a new generation. In vitro plant regeneration is a promising technique to overcome these barriers with explants. An efficiency of this protocol was established in dragon fruit using MS + 2.0 mg/L BA + 2.0 mg/L Kin. with explants, stem fraction. Eighty percent explants were responded for shoot initiation treated with 2.0 mg/L BAP in combination with 2 mg/L Kin. The highest number of shoots and the maximum shoot lengths were observed in this medium inoculation after 90 days. Shoots were transferred to media containing ½ strength of MS with root induced PGRs. Ninety percent of the in vitro raised shoots were responded for rooting treated with 2.5 mg/L IBA inoculation after 30 days. The highest number of roots and the maximum root lengths were recorded at 2.5 mg/L IBA. The response of inoculated explants or in vitro raised shoots were positively correlated with the number of shoots and roots respectively. The average shoot and root lengths were negatively correlated with each other resulting in root lengths increasing by decrease of shoot lengths. The healthy shoots with well rooted plantlets were transferred to natural condition where about 80% plantlets were found to be acclimatized.","PeriodicalId":400966,"journal":{"name":"International Journal of Biological and Pharmaceutical Sciences Archive","volume":"71 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140422978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hepatoprotective effect of the ethanol extract of Detarium senegalense stem bark in albino Wistar Detarium senegalense 茎皮乙醇提取物对白化 Wistar 动物肝脏的保护作用

International Journal of Biological and Pharmaceutical Sciences Archive Pub Date : 2024-02-28 DOI: 10.53771/ijbpsa.2024.7.1.0011

Umoke Chukwunalu Igbudu, Akuodor Godwin Christian, Okam Princeston Chukwuemeka, Okposhi Festus Toochukwu, Anele Donatus Onyebuchi, Onwe Kenneth Tochukwu, Nwokike Matthew Onyemaechi, Okoli Nnaemeka JC

{"title":"Hepatoprotective effect of the ethanol extract of Detarium senegalense stem bark in albino Wistar","authors":"Umoke Chukwunalu Igbudu, Akuodor Godwin Christian, Okam Princeston Chukwuemeka, Okposhi Festus Toochukwu, Anele Donatus Onyebuchi, Onwe Kenneth Tochukwu, Nwokike Matthew Onyemaechi, Okoli Nnaemeka JC","doi":"10.53771/ijbpsa.2024.7.1.0011","DOIUrl":"https://doi.org/10.53771/ijbpsa.2024.7.1.0011","url":null,"abstract":"Aim: The hepatoprotective effect of Detarium senegalense ethanol stem bark extract was evaluated against paracetamol induced hepatic damage in albino rats. Material and methods: The ethanol stem bark extract of D. senegalense at doses of 100 mg/kg, 200 mg/kg and 400 mg/kg were orally administered once daily for 3 days.The liver function tests and biochemical investigation such as asparte transaminase (AST), alanine transaminase (ALT), alkaline phosphatase (ALP), total bilirubin (TB) and direct bilirubin were carried out against paracetamol induced hepatotoxicity in rats. Phytochemical investigation was performed to find active constituents of the plant extracts by the different phytochemical tests. Results: Pre-treatment with the ethanol stem bark extract significantly prevented the biochemical, histological, and changes induced by paracetamol in the liver. The extract showed significant hepatoprotective effects as evidenced by decreased serum enzyme activities such as AST, ALT,, ALP, TB and DB which was supported by histopatological assessment of the liver.The ethanol stem bark extract exhibited significant hepatoprotective activity comparable with silymarin, the standard drug as well as hepatotoxin agent, paracetamol. The phytochemical screening of the extract revealed the presence of alkaloids, saponins, tannins, flavonoids, terpenoids, steroids, cardiac glycosides, resins and balsam. Conclusion: The results of this study strongly show that ethanol stem bark extract of Detarium senegalense possess a potent hepatotoxicity activity against paracetamol induced hepatic damage in rats.","PeriodicalId":400966,"journal":{"name":"International Journal of Biological and Pharmaceutical Sciences Archive","volume":"20 17","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140419732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Physicochemical characteristics and thin layer chromatography of the essential oil of spearmint: Mentha spicata L, from western Algeria 阿尔及利亚西部薄荷精油的理化特征和薄层色谱法阿尔及利亚西部的薄荷

International Journal of Biological and Pharmaceutical Sciences Archive Pub Date : 2023-12-30 DOI: 10.53771/ijbpsa.2023.6.2.0114

Bachir Nabti, Meriem Yasmine KELLOU, Djamel Boukhalfa

{"title":"Physicochemical characteristics and thin layer chromatography of the essential oil of spearmint: Mentha spicata L, from western Algeria","authors":"Bachir Nabti, Meriem Yasmine KELLOU, Djamel Boukhalfa","doi":"10.53771/ijbpsa.2023.6.2.0114","DOIUrl":"https://doi.org/10.53771/ijbpsa.2023.6.2.0114","url":null,"abstract":"The species chosen for this study is sweet mint, Mentha spicata L, harvested in the wilaya of El Bayadh in Algeria. The aim of this work is to highlight the plant's identification criteria, its yield in essential oil, the various physico-chemical parameters and the composition of the essential oil using different techniques (determination of several chemical indices and establishment of the list of constituents of the essential oil using chromatographic methods). The botanical study showed the presence of two types of \"Lamiaceae\" type secretory hairs. These secretory hairs are the histological support for the production and storage of essential oils. A study of the kinetics of the extraction yield shows that distillation is rapid from 0 to 120 minutes, when the yield reaches an optimum (1.08%). The organoleptic characteristics and physico-chemical indices obtained are in line with the standards given in the bibliography. Thin layer chromatography revealed the presence of several constituents through the appearance of several spots of different colour and Rf, three of which were identified by comparison with controls, namely menthol, cineol and carvone.","PeriodicalId":400966,"journal":{"name":"International Journal of Biological and Pharmaceutical Sciences Archive","volume":" 13","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139139485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessing the efficacy of home medication review in resolving drug-related problems in geriatric hypertensive patients: A community-based study 评估家庭用药检查在解决老年高血压患者用药相关问题方面的效果：一项社区研究

International Journal of Biological and Pharmaceutical Sciences Archive Pub Date : 2023-12-30 DOI: 10.53771/ijbpsa.2023.6.2.0119

Satish S, Fathima Shabna, Ramakrishna Shabaraya A.

{"title":"Assessing the efficacy of home medication review in resolving drug-related problems in geriatric hypertensive patients: A community-based study","authors":"Satish S, Fathima Shabna, Ramakrishna Shabaraya A.","doi":"10.53771/ijbpsa.2023.6.2.0119","DOIUrl":"https://doi.org/10.53771/ijbpsa.2023.6.2.0119","url":null,"abstract":"Home Medicines Review (HMR) is a health care service aimed to address various home medication management (HMM) issues which includes multiple services like maximizing knowledge regarding disease and its management, resolving drug-related problems and improving adherence to therapy. HMM issues are highly prevalent in geriatric patients owing to their chronic diseases like hypertension. The main objective of the study was to assess the impact of HMR in hypertensive geriatric patients in Dakshina Kannada. The study included 50 subjects of either gender over the course of 6 months on resolving patient DRP. The PCNE V9.01 was utilised for the purpose of identifying and categorizing the DRP. 78% had atleast one DRPs in their daily medication list. Pre-intervention study included pharmacist's interventions by oral counselling. Intervention was given at patient level only including lifestyle modifications, better medication practices wherever applicable. Patients requiring dosage adjustments, dosing schedule changes or an alternative drug therapy were referred to the prescriber. During post-intervention analysis out of the total 58 DRPs, 30 were resolved and 28 were not resolved as the study subjects did not see the physicians. Out of 39 interventions given 16 were accepted by the physician and appropriate decisions were made. This indicates a positive attitude towards intervention given by pharmacists. Conclusion: Home medication reviews proved to be an effective strategy in resolving DRPs among geriatric hypertensive patients in a community setting. This study highlights the importance of incorporating comprehensive medication management strategies into the care of older adults with chronic conditions, contributing to enhanced patient outcomes and overall healthcare quality. Further research is warranted to explore the long-term impact and cost-effectiveness of such interventions.","PeriodicalId":400966,"journal":{"name":"International Journal of Biological and Pharmaceutical Sciences Archive","volume":" 21","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139137786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pharmacist’s role in preventing drug abuse: A comprehensive review of illicit use of prescription and over-the-counter drugs for euphoric effects 药剂师在预防药物滥用方面的作用：对非法使用处方药和非处方药以达到兴奋效果的全面审查

International Journal of Biological and Pharmaceutical Sciences Archive Pub Date : 2023-12-30 DOI: 10.53771/ijbpsa.2023.6.2.0116

ZULEKA AMBRIN, K VINEETHA, A R SHABARAYA

{"title":"Pharmacist’s role in preventing drug abuse: A comprehensive review of illicit use of prescription and over-the-counter drugs for euphoric effects","authors":"ZULEKA AMBRIN, K VINEETHA, A R SHABARAYA","doi":"10.53771/ijbpsa.2023.6.2.0116","DOIUrl":"https://doi.org/10.53771/ijbpsa.2023.6.2.0116","url":null,"abstract":"The illicit use of prescription and over-the-counter drugs to achieve intoxication, commonly referred to as \"pharmaceutical highs,\" has emerged as a significant public health concern in recent years. The article begins by examining the reasons behind the illicit use of prescription and over-the-counter drugs, including the desire for euphoria, relaxation, enhanced cognitive performance, and self-medication for various psychological and physical conditions. It highlights the accessibility and perceived safety of these substances, as well as the influence of social and peer factors, as contributing factors to their misuse. To provide a comprehensive understanding, the review covers a wide range of prescription medicines such as quetiapine, gabapentinoids, Z-drugs, bupropion, venlafaxine, and over-the-counter medicines such as loperamide, dextromethorphan, benzydamine, promethazine, chlorphenamine, diphenhydramine and hyoscine butylbromide,codeine that have emerged as misused and diverted, or already described through the literature, as well as recorded by drug users through online websites reporting new trends and experimentations of drug abuse. It explores the pharmacological effects of these substances and their potential for abuse, dependence, and overdose. Additionally, it discusses the dangers of polydrug use, as individuals often combine multiple substances to potentiate their desired effects. Overall, Healthcare professionals should be aware of potential prescription drugs diversion, recognize misuse cases, consider the possibility of polydrug misuse, and prevent it where possible. Pharmacists can play a key role in preventing and reducing drug abuse and should be involved in evidence-based actions to detect, understand and prevent drug diversion activities and the adverse effects of drug-misuse.","PeriodicalId":400966,"journal":{"name":"International Journal of Biological and Pharmaceutical Sciences Archive","volume":" 64","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139137792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Methods to maintain a healthy life through ayurvedic dietetics namely Ahara Vidhi Visesayatana in the current scenario 在当前形势下通过阿育吠陀饮食学（即 Ahara Vidhi Visesayatana）保持健康生活的方法

International Journal of Biological and Pharmaceutical Sciences Archive Pub Date : 2023-12-30 DOI: 10.53771/ijbpsa.2023.6.2.0118

Jairam K V, Ajitha K, Anandalakshmy K N, Pradeep K, Abhilash M

{"title":"Methods to maintain a healthy life through ayurvedic dietetics namely Ahara Vidhi Visesayatana in the current scenario","authors":"Jairam K V, Ajitha K, Anandalakshmy K N, Pradeep K, Abhilash M","doi":"10.53771/ijbpsa.2023.6.2.0118","DOIUrl":"https://doi.org/10.53771/ijbpsa.2023.6.2.0118","url":null,"abstract":"The main component of the human body are water, protein, carbohydrates, fat and minerals which is obtained from the food. The proportion of these components may vary according to the age, sex and states of nutrition etc. Proteins, carbohydrates, fats, minerals, vitamins, and water are some of the important nutrients that make up food as a source of bio-energy. Ahara and the way it is consumed both carry identical values in Ayurveda. Ayurvedic philosophies clearly reflect the historical, empirical, and aesthetic part of Ahara Vidhi (Dietetics) and consider Ahara as Mahabhaishajya. Ingested food is bio-transformed into body entities. If food possess qualities opposite to body entities, such food keeps these body entities ill nourished. In recent times, due to the changes in life style which remarkably altering the diet pattern of an individual. As a result, one’s condition becomes so difficult that he/she is unable to take food as per his/her requisites. This paved the way to carry out a review on Asta Ahara vidhi visesayatana- eight factors which determine the outcome of various types of food in the current scenario.","PeriodicalId":400966,"journal":{"name":"International Journal of Biological and Pharmaceutical Sciences Archive","volume":" March","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139137245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Isolation of bacteria producing lipase from copra (Cocos nucifera l.) Cake for degradation of vegetable waste oils 从椰子饼（Cocos nucifera l.）中分离产生脂肪酶的细菌，以降解植物废油

International Journal of Biological and Pharmaceutical Sciences Archive Pub Date : 2023-11-30 DOI: 10.53771/ijbpsa.2023.6.2.0100

Priya R. Iyer, Kavyaja Mouri Bethapudi

引用次数: 0

Knowledge of childhood immunization among mothers in Umueze in 0sisioma Ngwa local government area of Abia State 阿比亚州西西奥马·恩格瓦地方政府地区乌穆韦兹母亲的儿童免疫知识

International Journal of Biological and Pharmaceutical Sciences Archive Pub Date : 2023-11-30 DOI: 10.53771/ijbpsa.2023.6.2.0105

None Prince Ezenwa Ndubueze Onyemachi

{"title":"Knowledge of childhood immunization among mothers in Umueze in 0sisioma Ngwa local government area of Abia State","authors":"None Prince Ezenwa Ndubueze Onyemachi","doi":"10.53771/ijbpsa.2023.6.2.0105","DOIUrl":"https://doi.org/10.53771/ijbpsa.2023.6.2.0105","url":null,"abstract":"Background: Childhood immunization almost guarantees protection from many major diseases, it is widely considered to be ‘overwhelmingly good’ by the scientific community. It averts an estimated 2.5 million deaths per year in all age groups from vaccine preventable diseases (VPD). Objective: To determine the knowledge of childhood immunization among mothers in Umueze in OsisiomaNgwa Local Government Area (LGA). Methods and materials: A cross-sectional study performed in Umueze Community in OsisiomaNgwa (LGA) in, Abia State, Nigeria. Self/interviewer questionnaires were administered to 480 women for the study. The collected data were cleaned, coded and entered into SPSS version 26 for analysis, Binary logistic regression analyses were performed to identify variables having a significant association with maternal knowledge. Result: A total of 480 women selected with a non-response rate of 30 (6.3%). Mean age was 35 ± 7.246. Majority of mothers 264 (58.7%) got information on immunization from health workers. Majority of mothers 300 (66.7%) believed that immunization is important. Three hundred and seventy (82.0%) believed that there was a benefit of immunization, 360 (80.0%) believed that immunization was free, 350 (77.8%) believed that lack of centres was the cause of reduced child immunization, 370 (82.2%) started immunizing their children after birth, 245 (54.4%) mothers gave their children all the immunization and 235 (54.7%) knew route of administration of BCG, while 355 (78.9%) women had good knowledge of immunization. Mothers who attended primary schools and above (AOR; 5.210 p = 0.002), married mothers (AOR; 4.224, p =0.03) Mothers age ≤ 35 years (AOR; 2.415 p = 0.001were statistically associated with maternal knowledgeable of immunization. Christian mothers (2.309, p = 0.12) were not statistically associated with maternal knowledge of immunization. Conclusion: Maternal knowledge of immunization is very important in immunization services.","PeriodicalId":400966,"journal":{"name":"International Journal of Biological and Pharmaceutical Sciences Archive","volume":"40 11","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136227844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mathematical Modelling of the Oral Administration of Drugs into the Stomach and the Treatment Effect with the Influence of Temperature 胃部口服给药的数学模型及温度影响下的治疗效果

International Journal of Biological and Pharmaceutical Sciences Archive Pub Date : 2023-11-30 DOI: 10.53771/ijbpsa.2023.6.2.0099

K.W. Bunonyo, L. Ebiwareme

引用次数: 0