Panagiota Zikidou, Rozeta Meziridou, Sonia Alexiadou, E. Mantadakis
{"title":"Acute Dystonic Reaction in a 14-Year-Old Boy after Accidental Overuse of Nasal Metoclopramide","authors":"Panagiota Zikidou, Rozeta Meziridou, Sonia Alexiadou, E. Mantadakis","doi":"10.1159/000512655","DOIUrl":"https://doi.org/10.1159/000512655","url":null,"abstract":"We present the case of a 14-year-old boy who developed an acute dystonic reaction 5 h following the overuse of a nasal metoclopramide spray that his mother gave him thinking it was a nasal decongestant. The patient had torticollis and intense motor restlessness, while he was fully conscious and hemodynamically stable. All laboratory investigations were normal. He was treated with a single dose of biperiden intravenously with direct disappearance of the symptoms. Children are particularly susceptible to the extrapyramidal side effects of metoclopramide that can occur irrespective of the route of administration.","PeriodicalId":400314,"journal":{"name":"Case Reports in Acute Medicine","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123780476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Acute Myocardial Infarction Complicated by Very Severe Hypertriglyceridemia","authors":"Gregory Wu, Brianna Bockman, J. Perez","doi":"10.1159/000511065","DOIUrl":"https://doi.org/10.1159/000511065","url":null,"abstract":"Hypertriglyceridemia (HTG) is the elevation of serum triglyceride levels above 150 mg/dL and is linked to complications such as pancreatitis and increased mortality risk. An uncommonly known co-presentation of HTG is acute ST-elevation myocardial infarction (STEMI), with the literature citing only one other case of acute STEMI complicated by very severe HTG. We report on a 36-year-old male with multiple comorbidities presenting with acute STEMI and elevated pancreatic enzymes suggestive of pancreatitis. A subsequent lipid profile revealed very severe HTG with a triglyceride level of 2,700 mg/dL. We discuss the pathogenesis, management, and screening guidelines of very severe HTG. Clinicians should be aware that acute STEMI complicated by HTG is rare and that earlier detection and intervention may allow for the prevention of life-threatening complications.","PeriodicalId":400314,"journal":{"name":"Case Reports in Acute Medicine","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125712772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. Chennu, P. Przydzial, Y. Tchao, Anthony Isedeh, N. Madan
{"title":"Pneumatocele after Acute Respiratory Distress Syndrome in an Adult Patient: A Case Report","authors":"G. Chennu, P. Przydzial, Y. Tchao, Anthony Isedeh, N. Madan","doi":"10.1159/000509870","DOIUrl":"https://doi.org/10.1159/000509870","url":null,"abstract":"Pulmonary pneumatocele is a cystic, air-filled lesion in the lung parenchyma. It results from underlying inflammation or bronchial injury. It is seen in several lung pathologies including bacterial pneumonia, positive-pressure ventilation, chest trauma, chemical pneumonitis, and is most often seen in infants and children. On imaging, pneumatoceles appear as rounded, thin-walled, air-filled spaces in the lung parenchyma. The exact mechanism for forming pneumatoceles is not fully understood but thought to be due to a check-valve mechanism due to obstruction by inflammation causing air trapping in the damaged lung. These lesions are asymptomatic and transient in most patients and disappear by about 6 weeks. They usually do not require any specific treatment or intervention. Surgical intervention is only necessary when pneumatoceles cause cardiopulmonary compromise or rupture into the pleural space. We describe a case of a young adult who developed a pneumatocele after developing acute respiratory distress syndrome from community-acquired pneumonia treated with positive-pressure ventilation. He was managed conservatively with complete resolution of symptoms.","PeriodicalId":400314,"journal":{"name":"Case Reports in Acute Medicine","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127920839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Drug Reaction with Eosinophilia and Systemic Symptoms Secondary to Naproxen: A Case Report and Literature Review","authors":"Sreethish Sasi, H. Altarawneh, M. Petkar, A. Nair","doi":"10.1159/000509712","DOIUrl":"https://doi.org/10.1159/000509712","url":null,"abstract":"Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a severe adverse drug reaction presenting with rash, fever, lymphadenopathy, and single or multiple organ involvement. It is most commonly associated with antiepileptics, NSAIDs, and sulfa drugs. We report a 40-year-old man who presented with a 1-week history of fever, sore throat, and a diffuse pruritic macular rash that started on the face and trunk before spreading to all extremities 4 weeks after the use of naproxen. He had lymphadenopathy, hepatosplenomegaly, transaminitis, and peripheral eosinophilia. A Registry of Severe Cutaneous Adverse Reactions (RegiSCAR) score of 8 gave a diagnosis of definite DRESS syndrome. Significant resolution of symptoms and laboratory abnormalities were seen after 2 weeks of corticosteroid therapy. DRESS syndrome is a life-threatening condition, and the clinical status of patients can worsen rapidly. Given the high variability in clinical presentation, the diagnosis of DRESS syndrome requires a high degree of suspicion and clinical judgment. Case reports on this entity will equip physicians in acute medicine to recognize and treat the condition early. This report reinforces the importance of using the RegiSCAR score in the diagnosis of DRESS syndrome.","PeriodicalId":400314,"journal":{"name":"Case Reports in Acute Medicine","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114213651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Lightning Injury with Multi-System Involvement","authors":"Ashwini Patankar, Smita Patil, S. Chandrakar","doi":"10.1159/000509456","DOIUrl":"https://doi.org/10.1159/000509456","url":null,"abstract":"Lightning leads to trauma and disability such as burns, hearing loss, blindness, cardiac arrhythmia, cardiac arrest, stroke, kidney injury, and can also lead to death. Such cases are seldom reported, and hence their database is scanty. We present a case of a 40-year-old female with lightning injury with four such manifestations, which is not commonly encountered. We have elaborated on these complications of lightning injury and their timely management, which has led us to good patient outcome.","PeriodicalId":400314,"journal":{"name":"Case Reports in Acute Medicine","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121950749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Muhammed Jasim Abdul Jalal, K. Iqbal, R. J. Mukkada, Rashmi Ratnakaran, Shani Basheer
{"title":"Gastric Antral Vascular Ectasia Associated with Asymptomatic Mixed Connective Tissue Disease Refractory to Endoscopic Treatment: A Rare Case","authors":"Muhammed Jasim Abdul Jalal, K. Iqbal, R. J. Mukkada, Rashmi Ratnakaran, Shani Basheer","doi":"10.1159/000509014","DOIUrl":"https://doi.org/10.1159/000509014","url":null,"abstract":"Gastric antral vascular ectasia (GAVE) constitutes 4% of all nonvariceal upper GI bleedings. It is characterized by the presence of erythematous or hemorrhagic ectatic vessels within the antrum that are distributed either in a striped or diffuse punctate pattern. We report a 64-year-old female without any co-morbidities, who presented with multiple episodes of blood in stools. Laboratory studies revealed a hemoglobin level of 5 g/dL with a hematocrit of 18.3%. Iron studies revealed a serum iron level of 35 μg/dL. She underwent an upper GI endoscopy, and biopsy was consistent with gastric antral vascular ectasia. ANA (antinuclear antibody), RA (rheumatoid factor), and anti-centromere antibody were all strongly positive. Erythrocyte sedimentation rate was 56. She was asymptomatic as far as connective tissue disease was concerned. Her anemia improved, but argon plasma coagulation failed to sustain the suppression of GAVE, and she required a blood transfusion for severe anemia on two occasions. With regard to recurrent episodes of melena, she was started on oral methyl prednisolone in a tapering dosage. She improved with medications, and her hemoglobin is maintained at 11.3 g/dL. This is the first unique case of GAVE in a patient without any other systemic illness or portal hypertension refractory to endoscopic treatment responding to monotherapy with corticosteroids.","PeriodicalId":400314,"journal":{"name":"Case Reports in Acute Medicine","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125141876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Varela, Luís Flores, Rui Patraquim, D. Nuñez, C. Granja
{"title":"A Rare Misdirected Subclavian Venous Catheter to the Neck","authors":"M. Varela, Luís Flores, Rui Patraquim, D. Nuñez, C. Granja","doi":"10.1159/000508701","DOIUrl":"https://doi.org/10.1159/000508701","url":null,"abstract":"Placement of a central venous catheter (CVC) is not without complications, one of those being misplacement of the catheter tip. This event is dependent on the patient’s vascular anatomy, hence unexpected misplacements may occur. We describe a case where a right subclavian CVC was inserted uneventfully, but later found to have migrated into a vein coursing through the midline of the neck, for which only three other cases have been reported. The catheter remained functional and was later removed without further complications.","PeriodicalId":400314,"journal":{"name":"Case Reports in Acute Medicine","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126567772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sreethish Sasi, A. Ahmed, Wajiha Yousuf, S. Vattoth
{"title":"Artery of Percheron Infarct: A Rare Presentation of Acute Ischemic Stroke in a High-Risk Antiphospholipid Syndrome Patient","authors":"Sreethish Sasi, A. Ahmed, Wajiha Yousuf, S. Vattoth","doi":"10.1159/000509569","DOIUrl":"https://doi.org/10.1159/000509569","url":null,"abstract":"Artery of Percheron (AOP) is an abnormal variant of the arterial supply of the thalamus. AOP occlusion can lead to bilateral thalamic and rostral midbrain infarct presenting as memory loss, fluctuating levels of consciousness, and altered mental status. A 43-year-old woman with a history of antiphospholipid syndrome (APS), managed on dabigatran, presented with acute confusion and drowsiness. She had slurred and slowed speech, disorientation in time and place, left-sided facial droop, decreased power of the left side (4/5), and was unable to walk due to generalized weakness. Labs showed a prolonged prothrombin time and activated partial thromboplastin time, positive lupus anticoagulant, anti-cardiolipin, beta-2 glycoprotein, anti-nuclear and anti-dsDNA antibodies. Contrast-enhanced CT perfusion showed ischemic changes in the bilateral thalami, suggesting infarct along the AOP territory. AOP infarcts are scarce and the presenting complaints are unusual of cerebrovascular accidents. It requires a high index of suspicion to detect. There are no other reports in the literature of patients with APS presenting with an AOP infarct. Considering the lack of evidence, we recommend against the use of newer oral anticoagulants (NOACs) for secondary prevention of vascular events in patients with triple-positive APS.","PeriodicalId":400314,"journal":{"name":"Case Reports in Acute Medicine","volume":"13 19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128555611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Spontaneous Tuberculosis-Associated Tension Pneumothorax: A Case Report and Literature Review","authors":"Aditya Doni Pradana","doi":"10.1159/000508530","DOIUrl":"https://doi.org/10.1159/000508530","url":null,"abstract":"Secondary spontaneous pneumothorax (SSP) is one of the major complications of pulmonary tuberculosis (TB), and it can be a life-threatening condition if it progresses to tension pneumothorax. A correct initial assessment and prompt intervention will prevent a hemodynamic deterioration in tension pneumothorax. Needle decompression followed by large-bore chest tube insertion is usually required in the management of SSP. We present a case of spontaneous TB-associated tension pneumothorax in a young adult which resolved with needle decompression without chest tube insertion.","PeriodicalId":400314,"journal":{"name":"Case Reports in Acute Medicine","volume":"86 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129861546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hemoperitoneum following a Motor Vehicle Accident in a Patient with 20 Uterine Leiomyomas","authors":"Gregory Wu, O. Urayeneza, G. Hinika","doi":"10.1159/000508347","DOIUrl":"https://doi.org/10.1159/000508347","url":null,"abstract":"Uterine leiomyomas are neoplasms of the smooth muscle that can cause complications such as severe bleeding and infertility in women of reproductive age. While many individuals may be asymptomatic, others may present with anemia secondary to heavy bleeding, cyclical abdominal pain, pelvic pressure, and urinary or bowel symptoms. A rare complication of uterine leiomyomas is avulsion due to blunt abdominal trauma resulting in hemoperitoneum. We present a 49-year-old female with no pertinent medical history who presented to the emergency room following a motor vehicle accident. Computed tomography scan revealed extensive hemoperitoneum and the patient was taken to the operating room where the source of bleeding was identified as multiple avulsed leiomyomas. The patient underwent an emergency hysterectomy and bilateral salpingectomy. Pathology reported a uterus weighing 6,000 g and the presence of 20 leiomyomas, with the largest measuring 29 cm. Knowledge of leiomyoma symptoms, presentation, and complications by both the patient and clinicians may help identify diagnoses and expedite intervention in the emergency setting.","PeriodicalId":400314,"journal":{"name":"Case Reports in Acute Medicine","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122986208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}