Case Reports in Acute Medicine最新文献

Urothelial Cell Carcinoma of the Bladder and Urinary Bladder Rupture as a Rare Cause of Acute Peritonitis: A Case Report 膀胱尿路上皮细胞癌和膀胱破裂是急性腹膜炎的罕见病因：病例报告

Case Reports in Acute Medicine Pub Date : 2024-03-21 DOI: 10.1159/000536581

Johnson Da Huang, Emily Ximin Shao, Alexander Ngoo, Chui Ming Tham, Handoo Rhee

{"title":"Urothelial Cell Carcinoma of the Bladder and Urinary Bladder Rupture as a Rare Cause of Acute Peritonitis: A Case Report","authors":"Johnson Da Huang, Emily Ximin Shao, Alexander Ngoo, Chui Ming Tham, Handoo Rhee","doi":"10.1159/000536581","DOIUrl":"https://doi.org/10.1159/000536581","url":null,"abstract":"Introduction: Urothelial carcinoma of the bladder causing spontaneous rupture of the bladder is an extremely rare condition with poor outcomes due to it being highly suggestive of advanced malignancy. Case Presentation: We present the case of a 74-year-old man who presented with non-specific signs and symptoms of abdominal pain and haematuria. Abdominal imaging was suggestive of a small bowel obstruction and a bowel perforation. At time of laparotomy, however, the patient was found to have metastatic urothelial carcinoma with peritoneal metastases. The patient unfortunately passed away 2 months following their initial presentation. Conclusion: Bladder perforation secondary to urothelial cancer is a rare pathology associated with poor prognosis. There are fewer than thirty cases reported in the literature, and it is often not considered during initial diagnostic workup of patients with abdominal sepsis in the context of bladder cancer. A high degree of suspicion for bladder rupture is recommended in patients with peritonism and urinary symptoms. Awareness of this condition will help facilitate prompt diagnosis and appropriate management.","PeriodicalId":400314,"journal":{"name":"Case Reports in Acute Medicine","volume":"231 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140222554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Massive Intoxication with 70 Tablets of Apixaban: A Case Report 70片阿哌沙班致大量中毒1例

Case Reports in Acute Medicine Pub Date : 2023-09-12 DOI: 10.1159/000533520

Tadahiro Kobayashi, Satoko Saito, Masayuki Takada, Kento Sakaguchi, Kazunori Takahashi, Ken Tanaka, Kaneyuki Kawamae, Masaki Nakane

{"title":"Massive Intoxication with 70 Tablets of Apixaban: A Case Report","authors":"Tadahiro Kobayashi, Satoko Saito, Masayuki Takada, Kento Sakaguchi, Kazunori Takahashi, Ken Tanaka, Kaneyuki Kawamae, Masaki Nakane","doi":"10.1159/000533520","DOIUrl":"https://doi.org/10.1159/000533520","url":null,"abstract":"Apixaban is a direct oral anticoagulation agent that exerts its effect through the direct inhibition of factor Xa. We treated a case of massive intoxication with 70 tablets of apixaban and have presented the clinical course of the associated anti-Xa activities. A 49-year-old woman was admitted to the emergency department approximately 1.5 h after impulsive self-intoxication with 175 mg of apixaban. She developed coagulopathy with prothrombin time-international normalized ratio (PT-INR) of 3.65, activated partial thromboplastin time of 56.5 s, and antithrombin activity (AT) of &gt;150% (at 1.5 h post-ingestion). The patient’s initial and peak anti-Xa activity was 17.7 IU/mL, and its elimination displayed first-order kinetics with a half-life of 10.5 h. The patient’s anti-Xa activity was within the therapeutic dose range at 26 h post-ingestion, and she recovered without experiencing any bleeding complications. Her coagulopathy also returned to normal level at the same timing. This result suggests that PT-INR and AT can be used as substitute markers of overwhelmed anticoagulation following massive overdose of apixaban. A case of apixaban overdose with associated anti-Xa activities was presented. There was favorable resolution of anticoagulation without specific treatments.","PeriodicalId":400314,"journal":{"name":"Case Reports in Acute Medicine","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135936377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Case Report of a Teaspoon Portion of Fava Beans Caused Severe Hemolysis in G6PD-Deficient Baby: Time to Include G6PD Enzyme Testing in the Premarital Screening Program and Newborns 一茶匙蚕豆导致G6PD缺陷婴儿严重溶血的病例报告:将G6PD酶检测纳入婚前筛查计划和新生儿的时间

Case Reports in Acute Medicine Pub Date : 2023-08-14 DOI: 10.1159/000531710

A. Alqarni, A. Hjazi

引用次数: 0

Life-Threatening Hyperkalemia following Low-Dose Trimethoprim-Sulfamethoxazole: A Case Report 低剂量甲氧苄啶-磺胺甲恶唑所致危及生命的高钾血症1例报告

Case Reports in Acute Medicine Pub Date : 2023-05-26 DOI: 10.1159/000530450

Hikaru Katagiri, N. Sato, Yukinori Inoue, Koji Muto, Hiroko Tanaka, Y. Hirose

引用次数: 0

Acute Esophageal Necrosis as an Unusual Cause of Epigastric Pain in the Emergency Department 急诊科急性食管坏死作为胃脘痛的一种罕见病因

Case Reports in Acute Medicine Pub Date : 2022-11-11 DOI: 10.1159/000527291

Tomoki Ito, K. Satoh, Kotaro Sakaki, M. Sakusabe

{"title":"Acute Esophageal Necrosis as an Unusual Cause of Epigastric Pain in the Emergency Department","authors":"Tomoki Ito, K. Satoh, Kotaro Sakaki, M. Sakusabe","doi":"10.1159/000527291","DOIUrl":"https://doi.org/10.1159/000527291","url":null,"abstract":"Epigastric pain is a common complaint in the emergency department (ED). Clinicians require skills to differentiate the epigastric pain in the ED. Here, we report a case of acute esophageal necrosis (AEN) as a cause of epigastric pain in the ED. An 83-year-old woman with diabetes mellitus visited the ED because of worsening subacute epigastric pain, nausea, and anorexia. The patient’s vital signs and general condition did not seem serious at first in the ED. Esophagogastroduodenoscopy revealed circumferential inflammation and necrosis of the esophageal mucosa. The patient was diagnosed with AEN and admitted. The patient’s condition suddenly worsened on the sixth day. Citrobacter koseri was detected in blood culture, and although the patient was treated with antibiotics, she died on the twelfth day. In our case, epigastric pain, a common complaint in the ED in elderly women, was caused by AEN, an uncommon disease. The patient was seemingly stable at first but rapidly developed sepsis and died. In this case, we identified two important clinical issues: (1) AEN is an uncommon cause of epigastric pain in the ED, but it is worth considering. (2) Once AEN is diagnosed, the clinician should engage in further investigations such as esophageal and blood culture tests and close follow-up of the clinical course, even if patients’ condition does not appear to be serious.","PeriodicalId":400314,"journal":{"name":"Case Reports in Acute Medicine","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114712178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Giant Colonic Diverticulum of the Sigmoid with an Unusual Localization 乙状结肠巨大憩室异常定位

Case Reports in Acute Medicine Pub Date : 2022-01-31 DOI: 10.1159/000518527

M. R. Frenken, Lisanne M. Koenjer, M. Versteegen, J. Vogelaar

引用次数: 0

Bell’s Palsy Caused by SARS-CoV-2 由SARS-CoV-2引起的贝尔氏麻痹

Case Reports in Acute Medicine Pub Date : 2021-11-15 DOI: 10.1159/000520124

M. Al-Kaisy, M. Eid

引用次数: 1

Recurrent Generalized Seizures with Postictal Todd’s Paralysis Caused by Medication-Associated Severe Hypomagnesemia: A Case Report 药物相关的严重低镁血症导致完全性托德麻痹的复发性全身性癫痫发作1例报告

Case Reports in Acute Medicine Pub Date : 2021-11-15 DOI: 10.1159/000520123

A. Khalil, Jithesh Choyi, K. Hossenbux, A. Taha

{"title":"Recurrent Generalized Seizures with Postictal Todd’s Paralysis Caused by Medication-Associated Severe Hypomagnesemia: A Case Report","authors":"A. Khalil, Jithesh Choyi, K. Hossenbux, A. Taha","doi":"10.1159/000520123","DOIUrl":"https://doi.org/10.1159/000520123","url":null,"abstract":"Hypomagnesemia is one of the electrolyte disturbances that can cause seizures. It is common in the hospitalized patients and can be induced by long-term usage of many medications. A 68-year-old male known to have hypertension and gastroesophageal reflux presented to the Emergency Department with an unprovoked first seizure at home followed by a temporary right-sided hemiparesis, dysphasia, and facial asymmetry. The hemiparesis, dysphasia, and facial asymmetry resolved within less than an hour after the seizure. His serum potassium was low with prolonged QT interval in the electrocardiogram (serum magnesium was not checked in the Emergency Department). He received intravenous IV potassium chloride infusion, and his serum potassium level was corrected, but he had a recurrent seizure after 10 h. At that time, his serum magnesium was found to be very low, he received IV magnesium sulfate infusion, and his indapamide, omeprazole, and metformin medications were stopped. He had no further seizures, the rest of his blood tests were normal, and his CT brain was unremarkable. He was treated for aspiration pneumonia, and his outpatient MRI brain and EEG came to be normal too.","PeriodicalId":400314,"journal":{"name":"Case Reports in Acute Medicine","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130811105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Traumatic Refractory Ventricular Fibrillation Successfully Treated with Intra-Arrest Esmolol 心脏骤停艾司洛尔成功治疗外伤性难治性心室颤动

Case Reports in Acute Medicine Pub Date : 2021-10-05 DOI: 10.1159/000518850

Kevin Raymond, E. Wheeler, M. Shank

引用次数: 1

Administration of Tranexamic Acid as Treatment for Angiotensin Converting Enzyme Inhibitor-Induced Angioedema: A Case Report 氨甲环酸治疗血管紧张素转换酶抑制剂诱导的血管性水肿1例报告

Case Reports in Acute Medicine Pub Date : 2021-07-19 DOI: 10.1159/000517621

S. Awsare, David Chirikian, J. Rogers

{"title":"Administration of Tranexamic Acid as Treatment for Angiotensin Converting Enzyme Inhibitor-Induced Angioedema: A Case Report","authors":"S. Awsare, David Chirikian, J. Rogers","doi":"10.1159/000517621","DOIUrl":"https://doi.org/10.1159/000517621","url":null,"abstract":"Background Angiotensin converting enzyme inhibitor-induced angioedema is a major cause of angioedema-related hospitalizations each year. Common swelling predilection sites include the face, periorbital skin, lips, pharynx, larynx, and tongue. Involvement of airway structures could lead to airway obstruction and ultimately death if not treated promptly. A 62-year-old man presented to a rural clinic with a massively swollen tongue that obscured visualization of the retropharynx and mildly swollen lips. The patient stated that he had been taking lisinopril for many years and never had a swelling episode similar to this. The patient was initially administered epinephrine, antihistamine, steroids, and Tranexamic acid. A second dose of Tranexamic acid was administered 30 min later followed by close monitoring. Seven hours after the first administration, the patient had near-complete resolution of tongue swelling and was later discharged. Angioedema treatment is still variable and hospitals in different settings may be able to take advantage of available resources for treatment. Tranexamic acid is a cheap and widely available antifibrinolytic that may be used to treat angiotensin converting enzyme inhibitor-induced angioedema, especially if more specific therapeutics are unavailable.","PeriodicalId":400314,"journal":{"name":"Case Reports in Acute Medicine","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134138407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4