{"title":"2D/3D Non-rigid Image Registration by an Efficient Demons Approach","authors":"Ashutosh Mishra, Pulak Mondal, S. Banerjee","doi":"10.1109/CBMS.2014.100","DOIUrl":"https://doi.org/10.1109/CBMS.2014.100","url":null,"abstract":"No rigid registration helps to recover local warping which occurs during image acquisition. The speed of operation is one of the bottlenecks in nonrigid registration which is addressed by only a few. In the present paper an efficient Demons approach is presented which not only increases the speed of the registration task, but also retains the performance of algorithm.","PeriodicalId":398710,"journal":{"name":"2014 IEEE 27th International Symposium on Computer-Based Medical Systems","volume":"100 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124751614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Computing Cardiac Strain from Variational Optical Flow in Four-Dimensional Echocardiography","authors":"Saurabh Vyas, J. Gammie, P. Burlina","doi":"10.1109/CBMS.2014.144","DOIUrl":"https://doi.org/10.1109/CBMS.2014.144","url":null,"abstract":"Myocardial strain is important to assess cardiac function and diagnose cardiovascular disease. Despite the adoption of 4D (volume + time) echocardiography for diagnostic and therapeutic purposes, current clinical practice often relies exclusively on 2D measurements of strain or flow information resulting from Doppler echography. However, strain is a 3D measure of deformation in the radial, circumferential and longitudinal directions and therefore full 3D strain, and in particular out-of- sagittal plane strain components, include important information for diagnostic purposes since they provide additional information on the manner in which the heart lengthens and contracts during diastole and systole. In our prior work, we have developed robust variational optical flow methods to estimate dense myocardial motion. In this study, we extend this methodology to track ventricular outlines, which are subsequently used to compute displacement and deformation fields. This in turn is used to compute volumetric estimates of strain. We test our methods on a dataset of 4D ultrasound acquired in vivo from seven patients, and find good agreement with physiological precepts.","PeriodicalId":398710,"journal":{"name":"2014 IEEE 27th International Symposium on Computer-Based Medical Systems","volume":"53 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115823400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Biological Image Indexing for Content-Based Retrieval of Drug Effects in Phenotypic Screening Data of Macroparasites","authors":"A. Gater, Rahul Singh","doi":"10.1109/CBMS.2014.19","DOIUrl":"https://doi.org/10.1109/CBMS.2014.19","url":null,"abstract":"Phenotypic-screening involves systematically assessing the therapeutic effects of a set of molecules by exposing entire disease systems to them and observing, through imaging, the effects of the compounds. Phenotypic assays typically generate hundreds of thousands to millions of images. An unmet challenge in this setting is to identify similar phenotypic effects caused by molecules, which may potentially be structurally different. While phenotypes can be compared using their feature vectors, real-time querying of these data sets becomes a challenging task because of the size of the data sets and the high dimensionality of the feature vectors. In this paper, we present an indexing approach that seeks to address this problem and allows efficient query-retrieval of phenotypic drug effects.","PeriodicalId":398710,"journal":{"name":"2014 IEEE 27th International Symposium on Computer-Based Medical Systems","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132651114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Popovic, Charalampos N. Moschopoulos, Ryo Sakai, A. Sifrim, J. Aerts, Y. Moreau, B. Moor
{"title":"A Self-Tuning Genetic Algorithm with Applications in Biomarker Discovery","authors":"D. Popovic, Charalampos N. Moschopoulos, Ryo Sakai, A. Sifrim, J. Aerts, Y. Moreau, B. Moor","doi":"10.1109/CBMS.2014.10","DOIUrl":"https://doi.org/10.1109/CBMS.2014.10","url":null,"abstract":"Recent developments in the field of-omics technologies brought great potential for conducting biomedical research in very efficient manner, but also raised a plethora of new computational challenges to be addressed. Extremely high dimensionality accompanied with poor signal-to-noise ratio and small sample size of data resulting from high-throughput experiments pose previously unprecedented problem, creating an increasing demand for innovative analytical strategies. In this work we propose an island model-based genetic algorithm for multivariate feature selection in the context of-omics data, which accommodates to a particular classification scenario via dynamic tuning of its parameters. We demonstrate it on two publicly available data sets containing gene expression profiles corresponding to the two distinct biomedical questions. We show that the algorithm consistently outperforms two additional feature selection schemes across data sets, regardless to which method is used in the subsequent classification step.","PeriodicalId":398710,"journal":{"name":"2014 IEEE 27th International Symposium on Computer-Based Medical Systems","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131035282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dmitri Wall, C. Hackett, B. Kane, K. Ahmad, B. Ramsay
{"title":"Electronic Health Records: A Survey of the Experiences and Expectations of Irish Dermatologists","authors":"Dmitri Wall, C. Hackett, B. Kane, K. Ahmad, B. Ramsay","doi":"10.1109/CBMS.2014.51","DOIUrl":"https://doi.org/10.1109/CBMS.2014.51","url":null,"abstract":"The potential of Electronic Health Records (EHRs) is widely recognised, however studies assessing dermatology end-users expectations and perceived benefits are lacking. We report on a survey of 142 physicians working in Dermatology in Ireland. Eight question stems assess experience with EHRs and expectations of an ideal system for use in Dermatology. 61 (43%) physicians responded, of which 27 (44%) describe their experience with EHRs. 6 (33%) of 18 suggest components of an ideal dermatology EHR (ease of data inputting, integration with laboratory systems and radiology, integration with administrative systems, photography, drawing tools and standardised nomenclature) rate between very important and vital. The usefulness of an ideal dermatology EHR rates between very and extremely useful across all categories proposed, with safety, building a National network and demonstrating the work performed by a department rating highest. This survey highlights the core needs of dermatology end-users, whose integral involvement is essential to ensure successful EHR implementation.","PeriodicalId":398710,"journal":{"name":"2014 IEEE 27th International Symposium on Computer-Based Medical Systems","volume":"71 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114262978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Defeasible Reasoning and Argument-Based Systems in Medical Fields: An Informal Overview","authors":"L. Longo, Pierpaolo Dondio","doi":"10.1109/CBMS.2014.126","DOIUrl":"https://doi.org/10.1109/CBMS.2014.126","url":null,"abstract":"The first aim of this article is to provide readers informally with the basic notions of defeasible and non-monotonic reasoning, logics borrowed from artificial intelligence. It then describes argumentation theory, a paradigm for implementing defeasible reasoning in practice as well as the common multi-layer schema upon which argument-based models are usually built. The second aim is to describe the selection of argument-based applications in the medical and health-care sectors. Finally, the paper will conclude with a summary of the features, which make defeasible reasoning and argumentation theory attractive, that emerge from the applications under review. The target reader is a medical or health-care practitioner, with limited skills in formal knowledge representation and logic, interested in enhancing evidence modelling and aggregation.","PeriodicalId":398710,"journal":{"name":"2014 IEEE 27th International Symposium on Computer-Based Medical Systems","volume":"126 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124015024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Applying Speculative Computation to Guideline-Based Decision Support Systems","authors":"Tiago Oliveira, J. Neves, P. Novais, K. Satoh","doi":"10.1109/CBMS.2014.32","DOIUrl":"https://doi.org/10.1109/CBMS.2014.32","url":null,"abstract":"Clinical Practice Guidelines, as evidence-based recommendations are the ideal support for Clinical Decision Support Systems. The intricacies of a guideline execution tool are related with the establishment of a care flow with an appropriate order between procedures and the modelling of decision points. One of such decision points is the choice between alternative tasks based on trigger conditions regarding a patient's state. It may be the case that, when there is the need to choose one of the alternative tasks, the system does not possess all the required information to do so, thus rendering impossible to reach an outcome. Speculative Computation and Abduction may increase the efficiency of this process by allowing the system to advance the computation of a solution, even while it is waiting for a response from the information sources. This work provides the basis for a Speculative Computation framework able to cope with decisions of clinical care flows. The methods developed herein were devised to support practitioners and to improve patient-centred medicine by providing maps of the most likely evolution of a patient, even when the information is incomplete.","PeriodicalId":398710,"journal":{"name":"2014 IEEE 27th International Symposium on Computer-Based Medical Systems","volume":"71 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124231329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Puel, A. V. Wangenheim, M. Meurer, D. D. J. D. Macedo
{"title":"BUCOMAX: Collaborative Multimedia Platform for Real Time Manipulation and Visualization of Bucomaxillofacial Diagnostic Images","authors":"A. Puel, A. V. Wangenheim, M. Meurer, D. D. J. D. Macedo","doi":"10.1109/CBMS.2014.12","DOIUrl":"https://doi.org/10.1109/CBMS.2014.12","url":null,"abstract":"This paper presents a technological solution with the purpose of collaborative medical image visualization with support of decision in telemedicine environments. A fully web-based modular platform was developed which contains visualization, marking and manipulation synchronized between multiple users with communication established through video call or text chat. Pure HTML5 was used ensuring the portability of the tool, meaning that any device with a modern web browser and internet connection can access it. Finally, the platform usability is confirmed by the excellent score resulted from a System Usability Scale evaluation.","PeriodicalId":398710,"journal":{"name":"2014 IEEE 27th International Symposium on Computer-Based Medical Systems","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122589786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluating a Row-Store Data Model for Full-Content DICOM Management","authors":"Alexandre Savaris, T. Härder, A. V. Wangenheim","doi":"10.1109/CBMS.2014.61","DOIUrl":"https://doi.org/10.1109/CBMS.2014.61","url":null,"abstract":"The management of data acquired in a daily basis, together with historical data kept available during variable time frames, became a practical concern to the healthcare practice. Data organized according to the DICOM (Digital Imaging and Communications in Medicine) standard contribute to this scenario, demanding solutions for storage and retrieval of metadata and images that lie beyond the customary file system approach. As a way of experimentation, this work defines and implements a data model using a NoSQL, row-store database, aiming to evaluate its suitability on managing DICOM content at tag level, as well as its performance when compared to a commonly approach based on a relational schema. The obtained results attest the capacity of the proposed model in storing full-content DICOM images, using tags as data units. In terms of performance, however, the data model is outperformed by the relational approach.","PeriodicalId":398710,"journal":{"name":"2014 IEEE 27th International Symposium on Computer-Based Medical Systems","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121019771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Benchmark of Globally-Optimal Anonymization Methods for Biomedical Data","authors":"F. Prasser, F. Kohlmayer, K. Kuhn","doi":"10.1109/CBMS.2014.85","DOIUrl":"https://doi.org/10.1109/CBMS.2014.85","url":null,"abstract":"Collaboration and data sharing have become core elements of biomedical research. At the same time, there is a growing understanding of privacy threats related to data sharing, especially when sensitive data from distributed sources become available for linkage. Statistical disclosure control comprises well-known data anonymization techniques that allow the protection of data by introducing fuzziness. To protect datasets from different types of threats, different privacy criteria are commonly implemented. Data anonymization is an important measure, but it is computationally complex, and it can significantly reduce the expressiveness of data. To attenuate these problems, a number of algorithms has been proposed, which aim at increasing data quality or improving efficiency. Previous evaluations of such algorithms lack a systematic approach, as they focus on specific algorithms, specific privacy criteria, and specific runtime environments. Therefore, it is difficult for decision makers to decide which algorithm is best suited for their requirements. As a first step towards a comprehensive and systematic evaluation of anonymity algorithms, we report on our ongoing efforts for providing an open source benchmark. In this contribution, we focus on optimal algorithms utilizing global recoding with full-domain generalization. We present a systematic evaluation of domain-specific algorithms and generic search methods for a broad set of privacy criteria, including k-anonymity, l-diversity, t-closeness and d-presence, and their use in multiple real-world datasets. Our results show that there is no single solution fitting all needs, and that generic search methods can outperform highly specialized algorithms.","PeriodicalId":398710,"journal":{"name":"2014 IEEE 27th International Symposium on Computer-Based Medical Systems","volume":"146 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116515983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}