Diabetes Spectrum最新文献_第2页

Optimizing Automated Insulin Delivery Systems for Pregnancy. 优化妊娠胰岛素自动输送系统。

Diabetes Spectrum Pub Date : 2025-11-14 eCollection Date: 2025-01-01 DOI: 10.2337/dsi25-0009

Emily D Szmuilowicz, Denice S Feig

引用次数: 0

Diabetes Spectrum Pub Date : 2025-11-14 eCollection Date: 2025-01-01 DOI: 10.2337/dsi25-0013

Nasim C Sobhani

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Racial Disparities in the Use of Automated Insulin Delivery Systems in Youth With Type 1 Diabetes. 1型糖尿病青少年使用自动胰岛素输送系统的种族差异

Diabetes Spectrum Pub Date : 2025-11-06 eCollection Date: 2025-05-01 DOI: 10.2337/ds25-0023

Emine G Yilmaz, Ksenia Tonyushkina, Sarah Ronis, Yuxi Zhu, Sarah A MacLeish

{"title":"Racial Disparities in the Use of Automated Insulin Delivery Systems in Youth With Type 1 Diabetes.","authors":"Emine G Yilmaz, Ksenia Tonyushkina, Sarah Ronis, Yuxi Zhu, Sarah A MacLeish","doi":"10.2337/ds25-0023","DOIUrl":"10.2337/ds25-0023","url":null,"abstract":"Objective: Automated insulin delivery (AID) systems improve glycemic outcomes in youth with type 1 diabetes and are now the recommended mode of insulin delivery. Previous studies highlighted racial disparities in the use of continuous glucose monitoring and insulin pump therapy. The purpose of this study was to evaluate the use of AID systems and A1C outcomes in youth with type 1 diabetes by race.Research design and methods: This was a single-center cross-sectional study. We included youth and young adults with type 1 diabetes aged 2-21 years who had at least two clinic visits between December 2022 and December 2023. Demographics, diabetes device use, and A1C data were gathered from chart review, based on the latest office visit records available in the electronic medical record system for 2023.Results: Out of 668 youth aged 3.1-19.9 years with type 1 diabetes, 435 (65%) were AID users. The prevalence of AID use was 70% (341 of 483) in White youth compared with 47% (60 of 129) among Black youth and 62% (34 of 55) among youth of other racial groups (P <0.001). Black youth using AID achieved significantly lower A1C levels (median 8%, interquartile range [IQR] 7.5-8.8%) compared with Black youth who did not use an AID system (median 9.6%, IQR 8.1-11.6%) (P <0.001).Conclusion: These findings support the persistence of racial disparities in diabetes technology utilization.","PeriodicalId":39737,"journal":{"name":"Diabetes Spectrum","volume":"38 5","pages":"611-616"},"PeriodicalIF":0.0,"publicationDate":"2025-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12784426/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145953376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Glucose Extremes and Cognitive Function: A Review of the Neurological Impacts of Hypoglycemia and Hyperglycemia in Type 1 Diabetes. 血糖极值和认知功能：1型糖尿病低血糖和高血糖的神经学影响综述。

Diabetes Spectrum Pub Date : 2025-11-05 eCollection Date: 2025-05-01 DOI: 10.2337/ds25-0012

David A Davis, Farzana Ferdous

{"title":"Glucose Extremes and Cognitive Function: A Review of the Neurological Impacts of Hypoglycemia and Hyperglycemia in Type 1 Diabetes.","authors":"David A Davis, Farzana Ferdous","doi":"10.2337/ds25-0012","DOIUrl":"10.2337/ds25-0012","url":null,"abstract":"This article explores the neurological impacts of hypoglycemia and hyperglycemia on cognitive function in type 1 diabetes. It reviews how fluctuating glucose levels disrupt critical brain metabolic pathways, impairing various cognitive processes such as memory, attention, and executive functioning. The authors highlight both the acute and long-term effects of glycemic variability on critical brain regions, including the hippocampus, prefrontal cortex, and occipital lobes. Notably, both hyperglycemia and hypoglycemia contribute to cognitive dysfunction but through different mechanisms. Hypoglycemia induces an energy crisis in the brain, triggering increased oxidative stress and neuronal vulnerability, with repeated episodes leading to cumulative hippocampal and prefrontal damage. Hyperglycemia results in vascular compromise, disrupting cerebral blood flow and leading to various states of neurotransmitter dysregulation, with chronic exposure being associated with structural changes such as reduced gray matter volume. Diabetes technology devices such as continuous glucose monitoring systems may reduce cognitive impairments associated with glucose fluctuations, but their benefits underscore the limitations of A1C alone and the need for metrics that better capture glycemic variability. This review underscores the need to prioritize glucose control to protect cognitive health in patients with type 1 diabetes.","PeriodicalId":39737,"journal":{"name":"Diabetes Spectrum","volume":"38 5","pages":"561-571"},"PeriodicalIF":0.0,"publicationDate":"2025-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12784436/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145953353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Partnering With Young Adults to Improve Engagement in Longitudinal Studies Across the Transition From Pediatric to Adult Type 1 Diabetes Care. 与年轻人合作，提高从儿童到成人1型糖尿病治疗过渡期间纵向研究的参与度。

Diabetes Spectrum Pub Date : 2025-11-05 eCollection Date: 2025-05-01 DOI: 10.2337/ds25-0057

Jessica S Pierce, Shilpa Gurnurkar, Keisha Bird, Amy Milkes, Susana R Patton

{"title":"Partnering With Young Adults to Improve Engagement in Longitudinal Studies Across the Transition From Pediatric to Adult Type 1 Diabetes Care.","authors":"Jessica S Pierce, Shilpa Gurnurkar, Keisha Bird, Amy Milkes, Susana R Patton","doi":"10.2337/ds25-0057","DOIUrl":"10.2337/ds25-0057","url":null,"abstract":"Young adults with type 1 diabetes face challenges transitioning from pediatric to adult health care, often resulting in gaps in or disengagement from care and suboptimal health outcomes. Longitudinal research during this period is critical to improve health outcomes, but is challenging. This study aimed to empirically evaluate technology-driven, stakeholder-informed strategies to improve longitudinal research study retention during the transition from pediatric to adult health care. In phase 1, we partnered with young-adult stakeholders to co-develop potential digital retention strategies. In phase 2, we enrolled 24 young adults with type 1 diabetes at their final pediatric diabetes clinic visit and assigned them to one of three retention strategy cohorts: weekly text messages, a digital study newsletter, or live virtual meetups. We followed participants for 12 months and assessed retention via completion of three study tasks: surveys, A1C kits, and glucose device downloads. All three strategies supported moderately high retention (71% at 12 months), but engagement in the strategies varied. The weekly text message cohort had the highest completion rates across tasks and required the least amount of research staff effort. In contrast, the digital study newsletter and virtual meetup strategies, although highly rated in phase 1, were labor-intensive and resulted in lower engagement. This study demonstrates the value of empirically testing stakeholder-informed digital retention strategies. Low-burden digital approaches such as text messaging may be both effective and scalable. Investing in small, pragmatic studies can improve the feasibility and impact of future longitudinal research in young adults with type 1 diabetes and other populations that are underrepresented in research.","PeriodicalId":39737,"journal":{"name":"Diabetes Spectrum","volume":"38 5","pages":"617-627"},"PeriodicalIF":0.0,"publicationDate":"2025-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12784437/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145953392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exploring the Role of Time in Diabetes Self-Management: A Scoping Review of Challenges, Intervention Strategies, and Implications for Clinical Care. 探索时间在糖尿病自我管理中的作用：挑战、干预策略和临床护理意义的范围综述。

Diabetes Spectrum Pub Date : 2025-11-04 eCollection Date: 2025-05-01 DOI: 10.2337/ds25-0050

Eyitayo O Owolabi, Michelle D S Boakye, Oluwatosin O Leshi, Shammah O Omololu, Brittany L Smalls

{"title":"Exploring the Role of Time in Diabetes Self-Management: A Scoping Review of Challenges, Intervention Strategies, and Implications for Clinical Care.","authors":"Eyitayo O Owolabi, Michelle D S Boakye, Oluwatosin O Leshi, Shammah O Omololu, Brittany L Smalls","doi":"10.2337/ds25-0050","DOIUrl":"10.2337/ds25-0050","url":null,"abstract":"Type 2 diabetes self-management behaviors (SMBs) can be time-consuming, necessitating effective time-management strategies. This scoping review synthesized evidence on the role of time and how time is conceptualized in diabetes self-management and identified strategies to address time-related barriers. Forty-eight peer-reviewed studies spanning 25 countries and published between 2013 and 2024 were included. Time scarcity, largely because of family, work, social, and caregiving responsibilities, was consistently identified as a barrier to SMBs, particularly physical activity (50% of studies), general self-management (21%), and dietary modifications (17%). Half of the studies proposed strategies to overcome time constraints, including structured routines, support from family and social networks, workplace accommodations, and digital health technologies. Five studies (10%) tested interventions, all of which used digital technologies. These findings emphasize that time-related barriers are pervasive and limit type 2 diabetes SMBs, highlighting an important consideration for diabetes educators and clinicians. Addressing time-related barriers will require multilevel approaches, including supporting individual time-management skills, leveraging interpersonal networks, and enacting structural changes in health care delivery and workplace policies. Greater investment in interventions, especially those extending beyond digital health, is needed to reduce the impact of time constraints on diabetes self-management.","PeriodicalId":39737,"journal":{"name":"Diabetes Spectrum","volume":"38 5","pages":"595-610"},"PeriodicalIF":0.0,"publicationDate":"2025-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12784438/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145953346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of a Pharmacist-Led Diabetes Management and Education Clinic on Glycemic Outcomes in Patients With Cancer. 以药剂师为主导的糖尿病管理和教育诊所对癌症患者血糖结局的评价。

Diabetes Spectrum Pub Date : 2025-10-30 eCollection Date: 2025-05-01 DOI: 10.2337/ds25-0059

Christina Louise Mnatzaganian, Mark Bounthavong, Cassandra Gehring, Lindsay MacLachlan, Panteha Kelly, Ila M Saunders

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Anxiety in Youth and Adults With Type 1 Diabetes and Associations With Clinical Outcomes: Data From the T1D Exchange Quality Improvement Collaborative. 青少年和成人1型糖尿病患者的焦虑及其与临床结果的关系：来自T1D交流质量改进协作的数据

Diabetes Spectrum Pub Date : 2025-10-28 eCollection Date: 2025-05-01 DOI: 10.2337/ds25-0021

Alissa Roberts, Emma Ospelt, Susan Thapa, Ryan McDonough, Grazia Aleppo, Marina Basina, Mary Lauren Scott, Kai E Jones, Kristina Cossen, Shideh Majidi, Jill Weissberg-Benchell, Cynthia Muñoz, Osagie Ebekozien

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Components and Effectiveness of Self-Management Interventions Among Adults Living With Type 2 Diabetes in Low-Income Countries: A Systematic Review. 低收入国家成人2型糖尿病患者自我管理干预的组成部分和有效性：一项系统综述

Diabetes Spectrum Pub Date : 2025-10-27 eCollection Date: 2025-05-01 DOI: 10.2337/ds25-0026

Arthur Kiconco, Sarah Rine, Kevin Folivi, Becky Alford, Lolia M Abibo, Ronald Anguzu, Joni S Williams, Roy William Mayega, Julia Dickson-Gomez

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Factors Considered Important by Diabetes Providers Before Recommending Automated Insulin Delivery Systems: Observations From the T1D Exchange Quality Improvement Collaborative. 糖尿病提供者在推荐自动胰岛素输送系统之前考虑的重要因素：来自T1D交换质量改进协作的观察

Diabetes Spectrum Pub Date : 2025-10-27 eCollection Date: 2025-05-01 DOI: 10.2337/ds25-0009

Osagie Ebekozien, McKing Amedari, Emma Ospelt, Susan Thapa, Ori Odugbesan, Ananta Addala

引用次数: 0