Journal of Medical and Dental Sciences最新文献_第8页

Reconstruction of small diameter arteries using decellularized vascular scaffolds. 去细胞血管支架重建小直径动脉。

Journal of Medical and Dental Sciences Pub Date : 2014-03-19 DOI: 10.11480/610105

Yuki Nagaoka, H. Yamada, Tsuyoshi Kimura, A. Kishida, T. Fujisato, K. Takakuda

引用次数: 15

Development of oral and extra-oral endosseous craniofacial implants by using a mesh structure for connective tissue attachment. 通过使用网状结构用于结缔组织附着的口腔和口腔外骨内颅面植入物的发展。

Journal of Medical and Dental Sciences Pub Date : 2014-03-19 DOI: 10.11480/610104

A. Mita, Atsushi Yagihara, Wei Wang, K. Takakuda

{"title":"Development of oral and extra-oral endosseous craniofacial implants by using a mesh structure for connective tissue attachment.","authors":"A. Mita, Atsushi Yagihara, Wei Wang, K. Takakuda","doi":"10.11480/610104","DOIUrl":"https://doi.org/10.11480/610104","url":null,"abstract":"Connective tissue attachment to a mesh structure incorporated on the surface of oral implants and extra-oral endosseous craniofacial implants (EOECI) was investigated. Two types of implants were prepared: TI and TI-Mesh. TI was composed of an upper and a lower component, both comprised of a titanium cylinder, which could be connected using a titanium screw. The composition of the TIMesh was similar, but the lower cylinder had a lateral groove that was covered with a titanium mesh. In animal experiments performed using rat calvaria, the lower component was first implanted and was left submerged for 3 weeks, then the upper component was mounted percutaneously. After an additional 2 weeks, each implant and the surrounding tissues were harvested and evaluated. Histological observations revealed collagen fibers originating from surrounding hypodermal tissues anchored to the mesh structures of the TI-Mesh whereas no such collagen fibers were observed around TI. Significantly greater values of the attachment strength, the thickness of the dermal tissue, the thickness of hypodermal tissue, and the attachment lengths were observed in TI-Mesh than those of TI. Thus connective tissue attachment with collagen fibers anchored to the mesh was achieved by incorporating mesh structures into the percutaneously placed implants.","PeriodicalId":39643,"journal":{"name":"Journal of Medical and Dental Sciences","volume":"61 1 1","pages":"23-31"},"PeriodicalIF":0.0,"publicationDate":"2014-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64196237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Vocal cord assessment with transnasal endoscopy in intubated patients after esophagectomy. 食管切除术后插管患者经鼻内镜声带评估。

Journal of Medical and Dental Sciences Pub Date : 2014-03-19 DOI: 10.11480/610103

A. Hoshino, K. Kawada, Y. Nakajima, K. Nagai, T. Sugimoto, T. Kawano

{"title":"Vocal cord assessment with transnasal endoscopy in intubated patients after esophagectomy.","authors":"A. Hoshino, K. Kawada, Y. Nakajima, K. Nagai, T. Sugimoto, T. Kawano","doi":"10.11480/610103","DOIUrl":"https://doi.org/10.11480/610103","url":null,"abstract":"BACKGROUND\u0000Vocal cord paralysis (VCP) is one of the postoperative complications after radical esophagectomy. VCP may also lead to serious morbidities such as respiratory distress and aspiration pneumonia. Therefore, an early diagnosis of VCP is meaningful in the postoperative management of patients undergoing esophagectomy. We evaluated a new practical method for diagnosing postoperative VCP.\u0000\u0000\u0000METHODS\u0000The laryngeal assessment of 30 patients was performed, and the presence of VCP was inferred while the following 15 patients by endoscopy before extubation after performing consecutive radical esophagectomy in 45 esophageal cancer patients. The vocal cord mobility, including adduction and abduction, were assessed by inserting the tip of a transnasal endoscope near the vocal cord in the awake patients with orotracheal intubation on the first postoperative day. The presence of VCP was reevaluated after extubation.\u0000\u0000\u0000RESULTS\u0000Eleven of the 30 patients assessed after radical esophagectomy had unilateral VCP and one patient had bilateral VCP. The abduction findings were useful for assessing VCP and the sensitivity, specificity, positive and negative predictive values and accuracy were 97.9%, 100%, 100%, 92.9% and 98.3%, respectively. The results of the following 15 patients were closely similar.\u0000\u0000\u0000CONCLUSIONS\u0000The VCP during orotracheal intubation is assessable by transnasal endoscopy.","PeriodicalId":39643,"journal":{"name":"Journal of Medical and Dental Sciences","volume":"61 1 1","pages":"17-22"},"PeriodicalIF":0.0,"publicationDate":"2014-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64196228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Effectiveness of setting numerical targets in the surgical training of residents: a trial to achieve an optimal balance. 在住院医师外科培训中设定数值目标的有效性:达到最佳平衡的试验。

Journal of Medical and Dental Sciences Pub Date : 2014-01-17

Kiyoshi Komiya, Momoko Saito, Yuika Sakurai, Hiromi Kojima, Kozo Takase

{"title":"Effectiveness of setting numerical targets in the surgical training of residents: a trial to achieve an optimal balance.","authors":"Kiyoshi Komiya, Momoko Saito, Yuika Sakurai, Hiromi Kojima, Kozo Takase","doi":"","DOIUrl":"","url":null,"abstract":"During the past 10 years, residency training in otorhinolaryngology-head and neck surgery (ORL-HNS) in Japan, especially at university hospitals, has emphasized subspecialization, resulting in insufficiencies in basic surgical techniques with an extreme bias toward acquiring subspecialty surgical case experience. To address this problem, we developed a target-oriented program intended to achieve a more balanced approach to surgical training and performed a 1-year trial of the program at the Jikei University School of Medicine. Fourteen residents with 1 to 4 years of ORL-HNS experience completed the trial. Each resident's competencies in six basic surgical procedures were assessed on the basis of the number of cases handled by the resident, and each resident's case selection bias after implementation of the target-oriented training was examined. The case selection bias in the trial group residents was reduced and their balance in case experience was shown to be improved in comparison with that in control group residents who were trained in the conventional way. In addition, opinion surveys of the participants and supervising otorhinolaryngologists (trainers) indicated that they felt that the new training system had been effective in improving the balance in case experience and improving motivation, and creating greater awareness of training goals and progress. ","PeriodicalId":39643,"journal":{"name":"Journal of Medical and Dental Sciences","volume":"60 4","pages":"93-101"},"PeriodicalIF":0.0,"publicationDate":"2014-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32063957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Changes in the microvascular structure of mucosal squamous cell carcinoma of the esophagus and their significance in tumor progression. 食管粘膜鳞状细胞癌微血管结构的变化及其在肿瘤进展中的意义。

Journal of Medical and Dental Sciences Pub Date : 2014-01-17

Jirawat Swangsri, Yasuaki Nakajima, Kenro Kawada, Yutaka Tokairin, Tomoyoshi Suzuki, Yutaka Miyawaki, Akihiro Hoshino, Takuya Okada, Shunsuke Ota, Tairo Ryotokuji, Naoto Fujiwara, Tetsuro Nishikage, Kagami Nagai, Hiroshi Kawachi, Tatsuyuki Kawano

{"title":"Changes in the microvascular structure of mucosal squamous cell carcinoma of the esophagus and their significance in tumor progression.","authors":"Jirawat Swangsri, Yasuaki Nakajima, Kenro Kawada, Yutaka Tokairin, Tomoyoshi Suzuki, Yutaka Miyawaki, Akihiro Hoshino, Takuya Okada, Shunsuke Ota, Tairo Ryotokuji, Naoto Fujiwara, Tetsuro Nishikage, Kagami Nagai, Hiroshi Kawachi, Tatsuyuki Kawano","doi":"","DOIUrl":"","url":null,"abstract":"Background: To identify the clinical T stage by endoscopy is a major diagnostic goal for superficial esophageal squamous cell carcinoma (ESCC). The completion of a microvascular morphological study of mucosal lesions is necessary to optimize therapy.Materials and methods: Images of 197 intra-papillary capillary loops (IPCLs) captured by magnified endoscopy from 15 esophagectomy specimens were studied for their morphological features and IPCL dimensions.Results: The microvascular morphology was classified into four basic major patterns: 1. spiral loop, 2. wide loop (WL), 3. globular (G) and 4. reticular pattern. The microvascular features and dimensions differed according to the depth of tumor invasion. Especially the mean bundle outline (IPCL diameter) showed significant changes as 20.02, 22.32, and 27.08 μm, respectively, for M1, M2 and M3, respectively (M1:M2 P < 0.05, M2:M3 P < 0.01).Conclusions: During tumor stage progression, a high-volume blood demand and cancer cell overgrowth to occupy the laminar propria mucosa (LPM) cause obvious elongation, thickening, branching, irregularity and deformity of the IPCL, which were characteristics of M3 lesions. The results of the present study support and can be applied with the current Japanese classification for improving the diagnostic accuracy, especially to differentiate between M2 and M3 lesions based on the endoscopic findings.","PeriodicalId":39643,"journal":{"name":"Journal of Medical and Dental Sciences","volume":"60 4","pages":"83-91"},"PeriodicalIF":0.0,"publicationDate":"2014-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32063956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effectiveness of setting numerical targets in the surgical training of residents: a trial to achieve an optimal balance. 在住院医师外科培训中设定数值目标的有效性:达到最佳平衡的试验。

Journal of Medical and Dental Sciences Pub Date : 2013-12-01 DOI: 10.11480/JMDS.600402

K. Komiya, Momoko Saito, Yuika Sakurai, H. Kojima, K. Takase

{"title":"Effectiveness of setting numerical targets in the surgical training of residents: a trial to achieve an optimal balance.","authors":"K. Komiya, Momoko Saito, Yuika Sakurai, H. Kojima, K. Takase","doi":"10.11480/JMDS.600402","DOIUrl":"https://doi.org/10.11480/JMDS.600402","url":null,"abstract":"During the past 10 years, residency training in otorhinolaryngology-head and neck surgery (ORL-HNS) in Japan, especially at university hospitals, has emphasized subspecialization, resulting in insufficiencies in basic surgical techniques with an extreme bias toward acquiring subspecialty surgical case experience. To address this problem, we developed a target-oriented program intended to achieve a more balanced approach to surgical training and performed a 1-year trial of the program at the Jikei University School of Medicine. Fourteen residents with 1 to 4 years of ORL-HNS experience completed the trial. Each resident's competencies in six basic surgical procedures were assessed on the basis of the number of cases handled by the resident, and each resident's case selection bias after implementation of the target-oriented training was examined. The case selection bias in the trial group residents was reduced and their balance in case experience was shown to be improved in comparison with that in control group residents who were trained in the conventional way. In addition, opinion surveys of the participants and supervising otorhinolaryngologists (trainers) indicated that they felt that the new training system had been effective in improving the balance in case experience and improving motivation, and creating greater awareness of training goals and progress.","PeriodicalId":39643,"journal":{"name":"Journal of Medical and Dental Sciences","volume":"60 4 1","pages":"93-101"},"PeriodicalIF":0.0,"publicationDate":"2013-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64011801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Changes in the microvascular structure of mucosal squamous cell carcinoma of the esophagus and their significance in tumor progression. 食管粘膜鳞状细胞癌微血管结构的变化及其在肿瘤进展中的意义。

Journal of Medical and Dental Sciences Pub Date : 2013-12-01 DOI: 10.11480/JMDS.600401

Jirawat Swangsri, Y. Nakajima, K. Kawada, Y. Tokairin, Tomoyoshi Suzuki, Y. Miyawaki, A. Hoshino, T. Okada, S. Ota, Tairo Ryotokuji, N. Fujiwara, T. Nishikage, K. Nagai, H. Kawachi, T. Kawano

{"title":"Changes in the microvascular structure of mucosal squamous cell carcinoma of the esophagus and their significance in tumor progression.","authors":"Jirawat Swangsri, Y. Nakajima, K. Kawada, Y. Tokairin, Tomoyoshi Suzuki, Y. Miyawaki, A. Hoshino, T. Okada, S. Ota, Tairo Ryotokuji, N. Fujiwara, T. Nishikage, K. Nagai, H. Kawachi, T. Kawano","doi":"10.11480/JMDS.600401","DOIUrl":"https://doi.org/10.11480/JMDS.600401","url":null,"abstract":"BACKGROUND\u0000To identify the clinical T stage by endoscopy is a major diagnostic goal for superficial esophageal squamous cell carcinoma (ESCC). The completion of a microvascular morphological study of mucosal lesions is necessary to optimize therapy.\u0000\u0000\u0000MATERIALS AND METHODS\u0000Images of 197 intra-papillary capillary loops (IPCLs) captured by magnified endoscopy from 15 esophagectomy specimens were studied for their morphological features and IPCL dimensions.\u0000\u0000\u0000RESULTS\u0000The microvascular morphology was classified into four basic major patterns: 1. spiral loop, 2. wide loop (WL), 3. globular (G) and 4. reticular pattern. The microvascular features and dimensions differed according to the depth of tumor invasion. Especially the mean bundle outline (IPCL diameter) showed significant changes as 20.02, 22.32, and 27.08 μm, respectively, for M1, M2 and M3, respectively (M1:M2 P < 0.05, M2:M3 P < 0.01).\u0000\u0000\u0000CONCLUSIONS\u0000During tumor stage progression, a high-volume blood demand and cancer cell overgrowth to occupy the laminar propria mucosa (LPM) cause obvious elongation, thickening, branching, irregularity and deformity of the IPCL, which were characteristics of M3 lesions. The results of the present study support and can be applied with the current Japanese classification for improving the diagnostic accuracy, especially to differentiate between M2 and M3 lesions based on the endoscopic findings.","PeriodicalId":39643,"journal":{"name":"Journal of Medical and Dental Sciences","volume":"60 4 1","pages":"83-91"},"PeriodicalIF":0.0,"publicationDate":"2013-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64011789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Evaluation of the occlusal contact of crowns fabricated with the bite impression method. 牙合印模法制备冠的咬合接触评价。

Journal of Medical and Dental Sciences Pub Date : 2013-09-30

Sachi Makino, Daizo Okada, Chiharu Shin, Reiko Ogura, Masaomi Ikeda, Hiroyuki Miura

{"title":"Evaluation of the occlusal contact of crowns fabricated with the bite impression method.","authors":"Sachi Makino, Daizo Okada, Chiharu Shin, Reiko Ogura, Masaomi Ikeda, Hiroyuki Miura","doi":"","DOIUrl":"","url":null,"abstract":"In prosthodontic treatment, reconstruction of a proper occlusal contact relationship is very important as well as reconstruction of a proper interproximal relationship and marginal fitness. Unfortunately, occlusal relationships are sometimes lost in the process of occlusal adjustment of crowns. The purpose of this study was to compare the occlusal contacts of single crown fabricated by two different types of impression techniques. Nine subjects, whose molars required treatment with crown restoration, were enrolled in this study. Full cast crowns were fabricated using two types of impression techniques: the conventional impression method (CIM) and the bite impression method (BIM). The occlusal contacts of crowns were precisely evaluated at the following stages: after occlusal adjustment on the articulator (Step 0), before occlusal adjustment in the mouth (Step 1), after occlusal adjustment at the intercuspal position (Step 2), and after occlusal adjustment during lateral and protrusive excursions (Step 3). The number of occlusal contacts of the crowns on the functional cusps fabricated with BIM was significantly greater than that with CIM after occlusal adjustment. For this reason, the crowns fabricated with BIM might have a more functionally desirable occlusal surface compared to the crowns fabricated with CIM. ","PeriodicalId":39643,"journal":{"name":"Journal of Medical and Dental Sciences","volume":"60 3","pages":"73-81"},"PeriodicalIF":0.0,"publicationDate":"2013-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40254728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficacy of lidocaine lontophoresis using either alternating or direct current in hairless rats. 交流电或直流电利多卡因对无毛大鼠lontopresis的影响。

Journal of Medical and Dental Sciences Pub Date : 2013-09-30 DOI: 10.11480/JMDS.600301

A. Nakajima, R. Wakita, H. Haida, H. Fukayama

{"title":"Efficacy of lidocaine lontophoresis using either alternating or direct current in hairless rats.","authors":"A. Nakajima, R. Wakita, H. Haida, H. Fukayama","doi":"10.11480/JMDS.600301","DOIUrl":"https://doi.org/10.11480/JMDS.600301","url":null,"abstract":"The aim of this study was to determine transport of lidocaine ions through a hairless rat skin in vivo and to compare the efficacy of alternating current (AC) with that of direct current (DC) iontophoresis (IOP). We measured the concentration of lidocaine transported through a cellophane membrane or a hairless rat dorsal skin applying either AC-IOP or DC-IOP. The results revealed that lidocaine concentration increased in a time-dependent manner in vitro in both DC-IOP and AC-IOP. However, the in vivo study showed different tendencies in lidocaine concentration. In the DCIOP group, lidocaine concentration reached its maximum 20 min after current application and then decreased rapidly; the AC-IOP group showed an increase in lidocaine concentration in a time-dependent manner. There were no side effects such as electrical burns in the rats. In conclusion, AC can be applied for long periods and DC for short periods, or their application time can be appropriately scheduled. Our study also suggests the mechanism by which voltage waveforms affect the skin when applied by IOP. In the future, these findings will be a solid foundation for developing various kinds of medical equipment such as scheduled drug delivery system that can easily deliver various types of drug.","PeriodicalId":39643,"journal":{"name":"Journal of Medical and Dental Sciences","volume":"60 3 1","pages":"63-71"},"PeriodicalIF":0.0,"publicationDate":"2013-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.11480/JMDS.600301","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64011728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Evaluation of the occlusal contact of crowns fabricated with the bite impression method. 牙合印模法制备冠的咬合接触评价。

Journal of Medical and Dental Sciences Pub Date : 2013-09-30 DOI: 10.11480/JMDS.600302

Sachi Makino, D. Okada, C. Shin, R. Ogura, M. Ikeda, H. Miura

{"title":"Evaluation of the occlusal contact of crowns fabricated with the bite impression method.","authors":"Sachi Makino, D. Okada, C. Shin, R. Ogura, M. Ikeda, H. Miura","doi":"10.11480/JMDS.600302","DOIUrl":"https://doi.org/10.11480/JMDS.600302","url":null,"abstract":"In prosthodontic treatment, reconstruction of a proper occlusal contact relationship is very important as well as reconstruction of a proper interproximal relationship and marginal fitness. Unfortunately, occlusal relationships are sometimes lost in the process of occlusal adjustment of crowns. The purpose of this study was to compare the occlusal contacts of single crown fabricated by two different types of impression techniques. Nine subjects, whose molars required treatment with crown restoration, were enrolled in this study. Full cast crowns were fabricated using two types of impression techniques: the conventional impression method (CIM) and the bite impression method (BIM). The occlusal contacts of crowns were precisely evaluated at the following stages: after occlusal adjustment on the articulator (Step 0), before occlusal adjustment in the mouth (Step 1), after occlusal adjustment at the intercuspal position (Step 2), and after occlusal adjustment during lateral and protrusive excursions (Step 3). The number of occlusal contacts of the crowns on the functional cusps fabricated with BIM was significantly greater than that with CIM after occlusal adjustment. For this reason, the crowns fabricated with BIM might have a more functionally desirable occlusal surface compared to the crowns fabricated with CIM.","PeriodicalId":39643,"journal":{"name":"Journal of Medical and Dental Sciences","volume":"60 3 1","pages":"73-81"},"PeriodicalIF":0.0,"publicationDate":"2013-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.11480/JMDS.600302","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64011737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1