Journal of Biomolecular Techniques最新文献

{"title":"مقارنة لبعض نماذج الانحدار المكاني باستخدام المحاكاة","authors":"Amna Hussein Shawq, Ismail Hadi Globe, Muktar Hussaini","doi":"10.51173/jt.v5i2.598","DOIUrl":"https://doi.org/10.51173/jt.v5i2.598","url":null,"abstract":"يعّد مرض سرطان الثدي من أكثر الامراض السرطانية شيوعا التي تصيب النساء على مستوى العالم ككل وتختلف معدلات الاصابة بين منطقة واخرى، يمكن دراسة هذه الظاهرة اعتمادا على تأثير المكان بدل السنوات وتتأثر البيانات المكانية بصورة مباشـرة بمجموعـة مـن العوامـل المـؤثرة (العمر، الموقع الجغرافي، الحالة الاجتماعية والاقتصادية والإنجابية، تناول الهرمونات، عوامل الخطر المتعلقة بنمط الحياة (التدخين، النظام الغذائي، السمنة والنشاط البدني)، والتاريخ العائلي التي تساهم بإظهار هذ المرض.\u0000في هذا البحث استخدم نماذج الانحدار المكاني  ( spatial regressive model ) لتحليـل البيانـات المكانية لمرض سرطان الثدي ومن  خـلال المقارنة التقدير بين نماذج الانحدار المكاني بواسطة محاكاة مونت كارلو لاختيار افصل مقدر بين النموذجي الانحدار المكاني الاول  نموذج الانحدار الذاتي المكاني (spatial autoregressive mode ) والثاني نموذج الخطأ المكاني( spatial error model)   وتطبيق  طريقتي التقدير طريقة المربعات الصغرى الاعتيادية وطريقة الامكان الاعظم على نماذج الانحدار ولغرض المقارنة استخدام  معيار المقارنة متوسط مربع الخطأ (Mean Square Error) على بيانات ذات عينات ومعلمات مختلفة للتحقق من أداء الطرائق واظهرت النتائج ان طريقة الامكان الاعظم لنموذج الانحدار الذاتي المكاني هي الافضل باختلاف حجم العينة المستعملة وعدد المتغيرات  التوضيحية.","PeriodicalId":39617,"journal":{"name":"Journal of Biomolecular Techniques","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89945789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Binary Classification of Customer’s Online Purchasing Behavior Using Machine Learning","authors":"A. Aldelemy, Raed A. Abd-Alhameed","doi":"10.51173/jt.v5i2.1226","DOIUrl":"https://doi.org/10.51173/jt.v5i2.1226","url":null,"abstract":"The UK financial sector increasingly employs machine learning techniques to enhance revenue and understand customer behaviour. In this study, we develop a machine learning workflow for high classification accuracy and improved prediction confidence using a binary classification approach on a publicly available dataset from a Portuguese financial institution as a proof of concept. Our methodology includes data analysis, transformation, training, and testing machine learning classifiers such as Naïve Bayes, Decision Trees, Random Forests, Support Vector Machines, Logistic Regression, Artificial Neural Networks, AdaBoost, and Gradient Descent. We use stratified k-folding (k=5) cross-validation and assemble the top-performing classifiers into a decision-making committee, resulting in over 92% accuracy with two-thirds voting confidence. The workflow is simple, adaptable, and suitable for UK banks, demonstrating the potential for practical implementation and data privacy. Future work will extend our approach to UK banks, reformulate the problem as a multi-class classification, and introduce pre-training automated steps for data analysis and transformation.","PeriodicalId":39617,"journal":{"name":"Journal of Biomolecular Techniques","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84798597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application of Overall Equipment Effectiveness for Optimizing Ventilator Reliability in Intensive Care Units and Emergency Departments","authors":"Khelood A. Mkalaf, Rami Hikmat Al-Hadeethi, Peter Gibson","doi":"10.51173/jt.v5i2.1419","DOIUrl":"https://doi.org/10.51173/jt.v5i2.1419","url":null,"abstract":"Healthcare organizations seek to offer a comprehensive medical services system framework with safety and high quality. This needs continuously developing integrated governance systems that provide safe, reliable, and maintaining high-quality care and value-based care for patients. In addition to improving access to health services in time, increasing efficiencies in providing medical services, reducing the risk-based medical services, and selecting a suitable maintenance policy for maintaining the medical devices. This paper adopted a quantitative analysis method based on Reliability-Based Maintenance (RCM) to comprehensively evaluate the overall medical equipment's effectiveness. RCM is an integrated approach to continuous improvement of the maintenance programs because it can predict early medical equipment failure and determine the mean time between failures. It also assesses the risk level to the patient's life in case of a medical equipment breakdown while provisioning medical services. This study targeted biomedical engineering, intensive care units, and emergency departments at 24 public hospitals in a top 20 OECD country. It selected these departments due to the rise in the rate of patients needing ventilator equipment availability during COVID-19, risk based on the sudden breakdown of the ventilator machines, and increasing the annual budget percentage required to provide medical services, where 239 of the ventilator equipment were investigated. Staff Experience-based Evidence was adopted to collect data by interviewing staff and distributing the survey. The study found that the average OEE for ventilator devices in Intensive Care Units and Emergency Departments was 63%. The device's performance was rated at 65%, while its availability and quality rate were both rated at 100%. These findings suggest that the use of the OEE metric has improved ventilator device reliability and performance in selected hospitals. The OEE metric may have potential benefits for improving the performance of other medical devices as well.","PeriodicalId":39617,"journal":{"name":"Journal of Biomolecular Techniques","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80103576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the Effect of Different Glazing Brands on Surface Roughness of Monolithic Zirconia","authors":"Riyam Imad Fouad, Lateef Essa, alwan Al Jorani, Abdel Kareem Jasim, Khadim Al-Azzawi","doi":"10.51173/jt.v5i2.940","DOIUrl":"https://doi.org/10.51173/jt.v5i2.940","url":null,"abstract":"The effect of glazing on the mechanical properties of monolithic high translucent zirconia is widely used to fabricate highly aesthetic and strong dental restorations using CAD-CAM technology. The purpose of this study was to evaluate the surface roughness of different glazing brands' materials on monolithic Zirconia. 40 specimens from Zirconia block (VITA YZ®XT Color, Diameter 98.4x14mm height) were prepared by computer-aided design/computer-aided manufacturing machined (Imes-Icore, 5 axis, COR TEC 250i dry, Germany). The samples dimension for the surface roughness test (diameter 10 mm and thickness 2 mm) by using a surface roughness testing machine profilometer (TR200, Germany), divided into 3 groups depending on types of glazing brands materials (VITA, VITA AKZENT® Plus, glaze LT, Germany), the second group with (Ivoclar Vivadent, IPS e.max Ceram glaze and stain liquid, Liechtenstein), and the third group with (GC Initial spectrum glaze liquid, Austria). The data were analyzed statistically using the package for social science, (ANOVA) test with the Bonferroni test to accept or reject the statistical hypothesis. For the roughness readings, the GC group had the greatest mean value of surface roughness in zirconia (0.721±0.014), followed Ivoclar group (0.663 ± 0.030), and then the VITA group (0.641±0.021). There was a statistically significant difference between (VITA&GC) and (Ivoclar & GC) with a p-value < 0.05, except between VITA with Ivoclar, there was no statistically significant association with a p-value > 0.05 for both. Zirconia glazed with GC paste (powder, fluid) has higher surface roughness than samples glazed with Ivoclar paste (powder, fluid) followed by the VITA group which has lower surface roughness. The results concluded that the monolithic zirconia glazed with GC glaze material displays a higher surface roughness than Ivoclar and VITA glaze.","PeriodicalId":39617,"journal":{"name":"Journal of Biomolecular Techniques","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74728750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Seroprevalence and Biomarkers Detection of Human Herpes Virus (HHV-8) in Patients with Kaposi Sarcoma","authors":"Abdulrazzaq N. Zghair, S. Kasim, Nazar Sh. Mohammed, Anil K Sharma","doi":"10.51173/jt.v5i2.857","DOIUrl":"https://doi.org/10.51173/jt.v5i2.857","url":null,"abstract":"Kaposi's sarcoma (KS) represents the most prevalent malignancy among untreated HIV-positive individuals. Herpesvirus linked with Kaposi's sarcoma (KSHV; also termed as human herpesvirus 8 (HHV8)). In this study, blood samples were collected from 120 individuals, 60 of them had HHV-8 infection with kaposi sarcoma and 60 persons as apparently healthy control. These patients attended Baghdad Teaching Hospital from the period of 15th February 2021 to 15th January 2022.\u0000Infections are seen to be more prevalent in the age group of 25-49 years when compared to other groups. The distribution of the biomarkers confirmed that 50, 25 and 80% of the 20 infected patients were positive for Ca19.9, Ca125 and Ca15.3 respectively. The Ca19.9, Ca125, and Ca15.3 biomarkers all produced good results in patients with Human Herpes Virus 8 (HHV-8) infections, leading us to the conclusion that these biomarkers gave favorable results. All of the PCR products showed a positive amplification at 434bp. Phylogenetic analysis confirmed the belongingness to the HHV strain. Further, this could lead to the development of a novel molecular diagnostic tool.","PeriodicalId":39617,"journal":{"name":"Journal of Biomolecular Techniques","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87232544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Concentration of Asprosin Associated with Poor Control of Type 2 Diabetes Mellitus in Diyala Province","authors":"Alaa Abed Mahmoud, Walaa Ismael Jassim, Ahmed Abdul Hussein Mohsin, Ahmed M. Senan","doi":"10.51173/jt.v5i2.932","DOIUrl":"https://doi.org/10.51173/jt.v5i2.932","url":null,"abstract":"A newly secreted adipokine called asprosin is brought on by fasting as well as encourages hepatic glucose release. Its loss of function through immunologic or genetic methods has a significant effect on lowering glucose and insulin as a result of decreased hepatic glucose release. This study aimed to measure the level of asprosin in a group of poor control hyperglycemic patients and compare its level with the control group and find its correlation with obesity and lipid profile. Asprosin level in serum was assessed by enzyme-linked immunosorbent assay (ELISA) technique for 110 Iraqi patients with type 2 diabetes mellitus(T2DM), as well as 70 individual healthy controls. Percentage of glycated hemoglobin (HbAIc), fasting blood glucose (FBG), total cholesterol (TC), triglyceride (TG), high-density lipoprotein (HDL) and low-density lipoprotein (LDL) concentration were calculated using Roche cobas integra 400 plus. Patients with type 2 diabetes mellitus reported increased levels of asprosin in their blood when compared with controls (p < 0.001). A significant positive correlation was seen between asprosin and FBG in patient’s (P< 0.05). Non-significant correlation was seen between asprosin and body mass index (BMI) or lipid profile. In conclusion, according to the asprosin level in serum, there was a highly significant difference between patients with type 2 diabetes mellitus and control group. BMI and lipid abnormalities were not correlated to asprosin level in the serum of patients.","PeriodicalId":39617,"journal":{"name":"Journal of Biomolecular Techniques","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77749349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Risk Factors of Chronic Kidney Disease among Patients Attending Medical City Complex","authors":"Nabaa Wisam Sabri, Buthaina Ateyah Rashid, Raheem Saber Shwiehk, Azad H. Mahdy","doi":"10.51173/jt.v5i2.885","DOIUrl":"https://doi.org/10.51173/jt.v5i2.885","url":null,"abstract":"Chronic kidney disease is a worldwide health problem that is defined as structural abnormalities or progressive or permanent loss of renal function for 3 months or more, which is usually associated with a decrease in glomerular filtration rate (GFR) of less than 60 mL/min/1.73 m2 or persistent proteinuria, which can lead to end-stage renal disease (ESRD) or kidney failure. To assess the risk factors leading to chronic kidney disease among the patients between cases and controls in the Medical City Complex. The study was conducted in hospitals of the medical city complex (Baghdad Teaching Hospital, Nursing Home Private Hospital, Ghazy Al-Hariri Hospital for Surgical Specialist, and kidney diseases and Transplant Center) in Baghdad, Iraq, and was designed as a case-control. There were 300 participants (150 cases and 150 controls). Data was collected over five months. The findings show that the highest percentage (20%) was within the age group 50–59 years old in the case study group, with a mean age of patients and controls of 47.71 ± 17.42 and 48.54 ± 17.43 years, respectively, and there were significant sociodemographic risk factors for CKD with gender and residency (p. value < 0.05). There was a significant link between medical history and the outcome of this investigation (p. value < 0.05 and OR > 1) All of the risk factors for CKD were hypertension, acute kidney disease, HCV infection, hyperlipidemia, renal stones, anemia, and cardiovascular disease. alcohol consumption had a significant difference with CKD (p. value =0.004). Increased intake of antihypertensive medical drugs also increases the risk of CKD (p. value =0.000). There is a significant association between patients' gender and residence, the patients with hypertension, AKI, HCV infection, hyperlipidemia, renal stones, anemia, and CVD had a significant relationship with CKD. The risk of CKD is increased in people who have had alcoholism and also in patients who have taken antihypertensive medication, The study recommends educating people about the risk factors of CKD, encouraging them to adopt a healthy diet, and healthy lifestyle, and encouraging alcohol cessation through special programs. The GFR test and other routine clinical tests must be performed regularly to monitor the change in kidney functions.","PeriodicalId":39617,"journal":{"name":"Journal of Biomolecular Techniques","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79329434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Flexure Strength of Heat Cure Acrylic Resin Reinforcement with Nano Al2O3 After Polishing with Different Abrasive Materials","authors":"Nihad AlFuraiji, W. Atallah, Syed Saad, B. Qasim","doi":"10.51173/jt.v5i2.1358","DOIUrl":"https://doi.org/10.51173/jt.v5i2.1358","url":null,"abstract":"Composites with Nano fillers reinforced by polymer structures are gaining popularity in the field of prosthodontic. Composite materials are being developed to meet the needs of patients, such as heat cure acrylic resins, that used so much in the field of prosthodontic.\u0000To evaluate the flexure strength of heat-cure acrylic resin reinforcement with Nano aluminum oxide (Al2O3) after polishing with various abrasive materials.\u0000A total of seventy rectangular specimens of heat cure acrylic resin with dimensions (65 mm length x 10 mm diameter x 3 mm thickness) Samples were separated into main seven groups classifications based on the addition of Nano Al2O3 and surface’s polishing with different abrasive materials. Each group have (10) specimens.\u0000The highest mean value of flexure strength was obtained in group (B) (87, while the lowest value was obtained in group (F) (56.9).\u0000It concluded that the flexure strength was decreased in groups (F and G) of heat-cured resin polished with diamond, while it was increased in groups (B and C) polished with pumice, followed by the control group(A), and then by groups (D and E) that polished with colloidal.","PeriodicalId":39617,"journal":{"name":"Journal of Biomolecular Techniques","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81505897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of IgG and Neutralizing Antibody Response After Pfizer BioNTech COVID-19 Vaccine Among Iraqi Individuals","authors":"Najat Saeed Hussein, Izzat Abdulsatar Al-Rayahi, Salwa S. Muhsin, Redhwan Abdul Kareem Alameer","doi":"10.51173/jt.v5i2.1267","DOIUrl":"https://doi.org/10.51173/jt.v5i2.1267","url":null,"abstract":"SARS-C0V-2 has quickly caused a pandemic. The distribution of vaccines is presently underway in an effort to stop the viral transmission and stop fatalities, several vaccinations have been created to decrease COVID virus disease, in 2019, the development of vaccine-induced population immunity is an important global strategy. Review of the anti-spike protein receptor-binding domain (S-RBD) a person's level of immune response to antibody strategy can be used to assess SARS-CoV-2 viral infection in 2019.  Their efficacy, safety, and immunogenicity in various population are not thoroughly understood. The objective of this study was to evaluate the vaccinations adverse effects as well as determine the immunogenicity of the messenger ribonucleic acid (mRNA) BNT162b2 vaccines through the production of IgG and neutralizing antibodies against the protein s subunit. A total of 41 vaccinated individuals with Pfizer-BioNTech COVID-19 vaccine, as well as (10) non vaccinated were included in the study.   Measurements of Neutralizing antibody (Nab) levels and CoV-IgG levels were tested by fluorescence Immunochromatographic assay. IgG and Nab levels showed a significant difference between its level in the sera of vaccinated and controls (p<0.05). This means the majority of immunization recipients between the ages of 18 -50 years can develop an immunological response to the SARS-Cov-2 vaccine.","PeriodicalId":39617,"journal":{"name":"Journal of Biomolecular Techniques","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84571193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mechanical Behaviour of Polymer Matrix Composite Reinforced by Silicon Carbide Particles","authors":"Muna Noori Ismael, Hazim F. Hassan","doi":"10.51173/jt.v5i2.949","DOIUrl":"https://doi.org/10.51173/jt.v5i2.949","url":null,"abstract":"In various fields, Polymer-based composites are used extensively instead of traditional materials. The hand lay-up technology has been employed to prepare the composites of Silicon carbide particles-epoxy. Mechanical properties; shore D hardness, Flexural strength, tensile strength and impact strength were measured for all specimens. The present work has also studied the impact of different weight percentages (including 3, 6, 9, 12, 15 and 18) wt.% of SiC solid powder on the mechanical properties of fabricated samples with two average particle sizes of 75 and 105 µm. SiC particles were utilized as reinforcement with the epoxy with hardener according to the mixing of (3:1) ratio. The experimental results found that hardness, flexural strength and impact strength can be increased by increasing the weight percentage of Silicon carbide, while tensile strength is decreased with an increased weight fraction of silicon carbide.  At the same time, these properties were enhanced when the particles of SiC have 75 µm more than at 105 µm.","PeriodicalId":39617,"journal":{"name":"Journal of Biomolecular Techniques","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79522102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}