{"title":"Do plasma-rich protein injections have a role in orthopaedics? A systematic review and meta-analysis of the randomized control trials","authors":"Marjan Raad, Priya Sekhon, Alastair Robertson","doi":"10.1016/j.mporth.2024.03.006","DOIUrl":"10.1016/j.mporth.2024.03.006","url":null,"abstract":"<div><p>We evaluated the effectiveness of plasma-rich protein injections (PRP) in terms of pain, patient-reported outcomes and function in degenerative joint disease and tendinopathy. The search strategies were ran in Ovid Medline and Ovid Embase in October 2023 by a clinical librarian. Results were limited to the last 10 years. The search terms used were ‘platelet rich plasma’ and ‘orthopaedics’. After screening and the eligibility process this resulted in 18 randomized control trials (RCTs). We analysed 18 level 1 RCTs in regard to gluteal tendinopathy, hip osteoarthritis, patella tendinopathy, knee osteoarthritis, Achilles tendinopathy, plantar fasciitis, rotator cuff tendinopathy and elbow tendinopathy. Further research, such as meta-analyses and double-blinded trials with more patients, longer follow-up and with a placebo group, is needed to better elucidate the safety and efficacy of PRP injections.</p></div>","PeriodicalId":39547,"journal":{"name":"Orthopaedics and Trauma","volume":"38 3","pages":"Pages 152-155"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141023637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Foot and ankle injuries in women's soccer: epidemiology and risk factors","authors":"Adrian J. Talia, Rick Brown","doi":"10.1016/j.mporth.2024.03.008","DOIUrl":"10.1016/j.mporth.2024.03.008","url":null,"abstract":"<div><p>This article provides a narrative summary of current understanding of football injuries in female athletes. We summarize the epidemiological data and compare differences between levels of competition, from amateur through professional. Underlying intrinsic risk factors such as anatomic, biomechanics and endocrine factors are outlined. Extrinsic risk factors such as football boot design and playing surface are detailed. We briefly report on the outcomes of women's injury prevention programmes and their success in reducing ankle injuries.</p></div>","PeriodicalId":39547,"journal":{"name":"Orthopaedics and Trauma","volume":"38 3","pages":"Pages 162-168"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141037704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Answers to the CME questions on Hip Fracture","authors":"","doi":"10.1016/j.mporth.2024.03.009","DOIUrl":"10.1016/j.mporth.2024.03.009","url":null,"abstract":"","PeriodicalId":39547,"journal":{"name":"Orthopaedics and Trauma","volume":"38 3","pages":"Page 180"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141038786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Frank Davis, Gareth Chan, Stephen Bendall, Benedict A. Rogers
{"title":"Sustainable orthopaedics: the needs and challenges","authors":"Frank Davis, Gareth Chan, Stephen Bendall, Benedict A. Rogers","doi":"10.1016/j.mporth.2024.03.007","DOIUrl":"10.1016/j.mporth.2024.03.007","url":null,"abstract":"<div><p>Climate change is undoubtedly a global threat, with extreme weather events, air pollution, and food insecurity disproportionately impacting low-income countries. The healthcare sector, whilst responsible for 4.4% of global net carbon emissions, has been slow in addressing its environmental footprint. This article explores the needs and challenges to achieve sustainable orthopaedic surgery. Orthopaedic surgery continues to create a large carbon footprint, primarily through the use of single-use consumables and energy-intensive operating theatres. While efforts to reduce environmental harm have primarily targeted changes within the operating theatre, a comprehensive approach must consider the entire surgical pathway. The principles of <em>reduce, reuse</em> and <em>recycle</em> are paramount. Reducing surgical caseload and advancing digital healthcare afford opportunities to streamline patient interactions, reduce travel emissions and improve efficiency. Furthermore, reevaluating routine practices, such as preoperative investigations and postoperative care, can minimize unnecessary resource consumption. Improving the sustainability of orthopaedics will bring conflicting clinical, financial and environmental challenges. However, with increasing awareness among healthcare professionals and support from it's professional bodies, there is growing momentum toward sustainable orthopaedic surgery. Transitioning to sustainable orthopaedic surgery neccesitates a broad approach encompassing prevention, optimization, and streamlining of the surgical pathway. Addressing environmental concerns alongside clinical outcomes is imperative for the future of orthopaedic surgery.</p></div>","PeriodicalId":39547,"journal":{"name":"Orthopaedics and Trauma","volume":"38 3","pages":"Pages 156-161"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141047860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Arthroplasty registries: a valuable tool to orthopaedic surgeons, manufacturers, patients and regulators?","authors":"Jasper G. Gerbers, Rob GHH. Nelissen","doi":"10.1016/j.mporth.2024.03.001","DOIUrl":"10.1016/j.mporth.2024.03.001","url":null,"abstract":"<div><p>Historically, orthopaedic implants required little clinical evidence before market introduction, either in the USA or the European Union (EU). There have been major incidents, with faulty designs or manufacturing techniques resulting in patient harm. The new EU Medical Device Regulations (MDR) have significantly changed the requirements around the introduction to the market of new medical devices in the EU. Initiatives like CORE-MD are founded to improve this process. EUDAMED will provide a mandatory European implant safety register. Real-world data, such as implant registries, have a major role to play in the continuous monitoring of implants, but this depends on them having high completeness (>95%) as well as coverage. Registries can also be used for post-market surveillance. Although implant registries use endpoints such as revision, as well as patient-reported outcomes, long-term follow-up is still needed to detect mediocre implants. For new designs, this often takes too long and potentially exposes patients to mediocre implants. This can be prevented by using more accurate, highly predictive methods at early follow-up (at 1 year), such as implant migration studies. Furthermore, registry-based or nested randomized controlled trials can be used to evaluate new implant designs and surgical techniques. Monitoring implants through registries remains vital in order to detect early or late unexpected failures related to the implant, surgical technique or indication, enhancing both implant development as well as patient safety.</p></div>","PeriodicalId":39547,"journal":{"name":"Orthopaedics and Trauma","volume":"38 3","pages":"Pages 118-123"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141032213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Human factors in trauma and orthopaedic surgery: a short overview","authors":"John A. Hardie, Peter A. Brennan","doi":"10.1016/j.mporth.2024.03.002","DOIUrl":"10.1016/j.mporth.2024.03.002","url":null,"abstract":"<div><p>A human factors (HF) approach can help optimize individual and team performance in healthcare and across related professions that work together. Trauma and orthopaedic surgeons carry out high-stakes tasks within a cognitively and physically demanding environment. This is compounded by the challenges of working in complex healthcare systems. Error is a ‘normal’ part of being human, and must be managed in order to prevent harm to patients and staff. HF is the science of how people work within their teams, and in the workplace. It examines interactions with equipment, and the processes used to achieve the desired outcome. It uses theory from fields as diverse as ergonomics, psychology and engineering in order to achieve these aims. This article outlines key topics relevant to surgeons striving to help improve patient safety and wellbeing within teams. These include theories of error in healthcare, systems-based approaches, performance-limiting factors, and non-technical skills.</p></div>","PeriodicalId":39547,"journal":{"name":"Orthopaedics and Trauma","volume":"38 3","pages":"Pages 124-129"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141054909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Management of haematogenous bone and joint infection in developing countries","authors":"Myung-Sang Moon","doi":"10.1016/j.mporth.2024.03.005","DOIUrl":"10.1016/j.mporth.2024.03.005","url":null,"abstract":"<div><p>Haematogenous pyogenic bone and joint infection is rarely seen in developed countries, but in the developing world it is still a major and common problem. New forms of acute fulminating osteomyelitis are likely to appear due to immunosuppression in the wake of the worldwide spread of HIV infection, AIDS, and the increased use of steroids, antibiotics, and immune activators. Osteomyelitis due to candida and cryptococcus infection in certain regions, are occasionally observed, whilst osteomyelitis that is resistant to treatment is associated with diabetes mellitus. Bone and joint infections are difficult to cure. This difficulty is related to the presence of bacteria adherent to dead bone and foreign material in many cases, and also to the drug resistance and limited penetration of antibiotics into infected bone. This presentation summarizes present knowledge of bone and joint infection and its management.</p></div>","PeriodicalId":39547,"journal":{"name":"Orthopaedics and Trauma","volume":"38 3","pages":"Pages 145-151"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141057659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Justine Burt, Andrew Brunt, Andrew J. Hall, Jon V. Clarke, Phil Walmsley
{"title":"The Scottish Arthroplasty Project: Scotland's approach to a National Joint Registry","authors":"Justine Burt, Andrew Brunt, Andrew J. Hall, Jon V. Clarke, Phil Walmsley","doi":"10.1016/j.mporth.2024.03.003","DOIUrl":"10.1016/j.mporth.2024.03.003","url":null,"abstract":"<div><p>The core function of joint registries is to collect, collate, and present data about patients who undergo joint replacement surgery, and afford clinicians and administrators a range of analytic functions to monitor service performance. This article describes the development, evolution, and future of arthroplasty registries, drawing particularly from the experience of the Scottish Arthroplasty Project (SAP). The SAP was established in 1999 and is one of the oldest arthroplasty registries in the world. It collects information on patients undergoing hip, knee, ankle, shoulder, and elbow arthroplasty. The primary aim is to encourage continual improvement in the quality of care provided for arthroplasty patients in Scotland. It is distinct in terms of administration and methodology from the National Joint Registry (NJR) of England, Wales, and Northern Ireland as it monitors patients rather than implants. Since its inception, its work has contributed to a reduction in overall complication rates and a significant decrease in hospital length of stay for the growing number of patients undergoing arthroplasty. It continues to provide a robust database that is used to underpin national guidance through data-driven research. The research carried out by dedicated SAP fellows has enhanced the research portfolio of the SAP and raised its profile through high quality peer-reviewed publications. The SAP continues to evolve and by collaborating with other Scottish registries it will provide larger datasets containing greater diversity and granularity of information. These developments as well as ongoing analysis of existing areas ensure that the SAP continues to maintain and improve standards in arthroplasty across Scotland.</p></div>","PeriodicalId":39547,"journal":{"name":"Orthopaedics and Trauma","volume":"38 3","pages":"Pages 130-136"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141044852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Skeletal muscle structure, function and pathology","authors":"James Allen, Mark Ramsden, Sohail Nisar","doi":"10.1016/j.mporth.2024.03.004","DOIUrl":"10.1016/j.mporth.2024.03.004","url":null,"abstract":"<div><p>Skeletal muscle is an important structure responsible for producing movement, storing nutrients, maintaining posture and providing stability across joints. Unlike smooth and cardiac muscle, control can be voluntary. This review article will outline the macroscopic and microscopic appearance of skeletal muscle, the method by which it contracts, the types of skeletal muscle and pathology associated with it.</p></div>","PeriodicalId":39547,"journal":{"name":"Orthopaedics and Trauma","volume":"38 3","pages":"Pages 137-144"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141024242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reducing morbidity and mortality in the hip fracture patient group","authors":"Martyn J Parker","doi":"10.1016/j.mporth.2024.01.004","DOIUrl":"https://doi.org/10.1016/j.mporth.2024.01.004","url":null,"abstract":"<div><p>A review of the literature was undertaken to determine which amenable factors could be identified that would potentially improve the morbidity or mortality after hip fracture. Only four factors were identified that have been clearly reported to be associated with a reduction in mortality or morbidity, these were early surgery, cemented arthroplasty and experience of the surgeon and peri-operative antibiotics. Five interventions were identified that may reduce mortality or morbidity: nerve blocks, nutritional support, pharmacological thromboembolic prophylaxis, mechanical intermittent pneumatic compression and nail fixation of extracapsular fractures. Several other factors were identified for which it remains uncertain if they will reduce mortality or morbidity: preoperative assessment, β-blockers, blood transfusion, anti-embolism stockings, choice of surgical implant, cardiac output monitoring during surgery, choice of anaesthesia, prevention of intraoperative hypotension, anabolic steroids, multidisciplinary care, and rehabilitation. Continuing research is required to define which interventions are clearly effective and to further identify any adverse effects.</p></div>","PeriodicalId":39547,"journal":{"name":"Orthopaedics and Trauma","volume":"38 2","pages":"Pages 89-94"},"PeriodicalIF":0.0,"publicationDate":"2024-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140290529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}