Orthopaedics and TraumaPub Date : 2026-08-01Epub Date: 2026-07-10DOI: 10.1016/j.mporth.2026.05.006
Benjamin Holmes, Valeria Pintar, Athanasios I. Tsirikos
{"title":"Bridging the gap: the role of biologics in trauma and orthopaedics","authors":"Benjamin Holmes, Valeria Pintar, Athanasios I. Tsirikos","doi":"10.1016/j.mporth.2026.05.006","DOIUrl":"10.1016/j.mporth.2026.05.006","url":null,"abstract":"<div><div>Orthobiologics are biological materials used to augment the body's intrinsic repair mechanisms. The use of orthobiologics in trauma and elective orthopaedics continues to expand with an increasing understanding of cellular signalling pathways and biomaterials science. Applications now span fracture and non-union management, spinal fusion, cartilage restoration, and tendon repair. This review summarizes current evidence, biological principles, regulatory and economic considerations within the UK, and highlights future directions. Orthobiologics act by providing cells, signalling molecules and scaffolds to enhance osteogenesis, chondrogenesis and angiogenesis. Although several agents, most notably bone morphogenetic proteins (BMPs) and platelet-rich plasma (PRP), have achieved limited clinical acceptance, widespread use remains constrained by variable efficacy, cost and regulatory oversight. A structured understanding of biological mechanisms and appropriate indications is essential for orthopaedic surgeons engaged in trauma or elective practice.</div></div>","PeriodicalId":39547,"journal":{"name":"Orthopaedics and Trauma","volume":"40 4","pages":"Pages 219-225"},"PeriodicalIF":0.0,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148666853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Orthopaedics and TraumaPub Date : 2026-08-01Epub Date: 2026-07-08DOI: 10.1016/j.mporth.2026.05.010
{"title":"Answers to the CME questions on The Shoulder","authors":"","doi":"10.1016/j.mporth.2026.05.010","DOIUrl":"10.1016/j.mporth.2026.05.010","url":null,"abstract":"","PeriodicalId":39547,"journal":{"name":"Orthopaedics and Trauma","volume":"40 4","pages":"Page 253"},"PeriodicalIF":0.0,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148666858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Orthopaedics and TraumaPub Date : 2026-06-01Epub Date: 2026-05-13DOI: 10.1016/j.mporth.2026.03.002
Danilo Vukanic, Connor Kilkenny, Alexandre Lädermann, Chris A Peach
{"title":"How do I influence healing in rotator cuff repairs?","authors":"Danilo Vukanic, Connor Kilkenny, Alexandre Lädermann, Chris A Peach","doi":"10.1016/j.mporth.2026.03.002","DOIUrl":"10.1016/j.mporth.2026.03.002","url":null,"abstract":"<div><div>Rotator cuff tears are common in the older population, and the volume of rotator cuff repair continues to rise. Despite refinements in technique, structural failure remains frequent, with reported re-tear rates often over 25% at medium-term follow-up. The first 6 months after repair represent a critical period for failure risk. This review focuses on patient, surgeon and implant factors that influence tendon healing and highlights areas where clinicians can intervene. Increasing age, larger tears, degree of tendon retraction, fatty infiltration and muscle atrophy consistently predict non-healing and should inform counselling and operative planning. Potentially modifiable patient factors include glycaemic control, body mass index, nutrition, vitamin D status and bone mineral density. On the surgical side, repair configuration and mechanical stability appear most important for larger tears, while the benefits of routine subacromial decompression or footprint microfracture remain uncertain. Augmentation options such as dermal allografts, platelet-rich plasma and bioinductive collagen implants may improve structural integrity in high-risk tears, although consistent functional gains have not been demonstrated. A pragmatic approach combines risk stratification with optimization of modifiable factors, robust fixation and a rehabilitation programme that protects the repair while restoring function.</div></div>","PeriodicalId":39547,"journal":{"name":"Orthopaedics and Trauma","volume":"40 3","pages":"Pages 139-145"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148153666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Orthopaedics and TraumaPub Date : 2026-06-01Epub Date: 2026-06-04DOI: 10.1016/j.mporth.2026.03.004
Adrian Andronic
{"title":"Managing glenoid bone loss: implications for instability surgery and shoulder arthroplasty","authors":"Adrian Andronic","doi":"10.1016/j.mporth.2026.03.004","DOIUrl":"10.1016/j.mporth.2026.03.004","url":null,"abstract":"<div><div>Glenoid bone loss significantly affects outcomes in shoulder instability surgery and arthroplasty. Recognizing and addressing glenoid bone loss is essential to reduce the risk of recurrent instability, implant failure and early revision. Advances in biomechanics, imaging, preoperative planning and surgical techniques have changed management strategies over the past two decades. Clinical decisions remain challenging, and must be patient-specific. This review provides an evidence-based overview of glenoid bone loss assessment and management. It focuses on two main areas: recurrent shoulder instability and primary and revision shoulder arthroplasty. For instability, the pathoanatomy of glenoid and bipolar bone loss is discussed alongside clinical assessment, imaging strategies and thresholds for critical and subcritical defects. The role of the glenoid track concept in refining risk stratification and guiding surgical decision-making is examined, with emphasis on selecting between soft-tissue stabilization, remplissage and bony augmentation procedures. In arthroplasty, patterns of glenoid bone loss, classification systems and advances in three-dimensional imaging and preoperative planning are reviewed. Contemporary management options for both anatomic and reverse shoulder arthroplasty are explored, including bone grafting, augmented components and custom solutions. Accurate assessment and patient-specific strategies are central to the successful management of glenoid bone loss.</div></div>","PeriodicalId":39547,"journal":{"name":"Orthopaedics and Trauma","volume":"40 3","pages":"Pages 151-156"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148153668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Orthopaedics and TraumaPub Date : 2026-06-01Epub Date: 2026-05-13DOI: 10.1016/j.mporth.2026.03.005
Samuel Crompton, Emma Rowbotham, Richard Fawcett
{"title":"Shoulder imaging: a practical review","authors":"Samuel Crompton, Emma Rowbotham, Richard Fawcett","doi":"10.1016/j.mporth.2026.03.005","DOIUrl":"10.1016/j.mporth.2026.03.005","url":null,"abstract":"<div><div>The radiological evaluation of shoulder disorders has evolved to incorporate virtually all imaging modalities. This article discusses the varying roles of these modalities and includes key points for understanding the indications, diagnostic value and limitations of each. Plain radiography, ultrasound, computed tomography and magnetic resonance imaging (including magnetic resonance arthrography) are discussed, as well as recent innovations in these fields. The optimum imaging method for the diagnosis of specific shoulder pathologies, such as fracture, rotator cuff tendon disease and arthropathy is discussed, whilst incorporating useful advice on diagnostic accuracy and availability from the radiologist's perspective. The purpose is to give an overview and a general approach to the imaging diagnosis of shoulder disorders to inform current and future orthopaedic practice.</div></div>","PeriodicalId":39547,"journal":{"name":"Orthopaedics and Trauma","volume":"40 3","pages":"Pages 157-164"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148153669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Orthopaedics and TraumaPub Date : 2026-06-01Epub Date: 2026-05-13DOI: 10.1016/j.mporth.2026.03.001
Simon Woods, Mark Philipson, Paul Cowling
{"title":"Implant options in primary shoulder arthroplasty: where are we now? A review of indications and survivorship based on registry data","authors":"Simon Woods, Mark Philipson, Paul Cowling","doi":"10.1016/j.mporth.2026.03.001","DOIUrl":"10.1016/j.mporth.2026.03.001","url":null,"abstract":"<div><div>Shoulder arthroplasty has evolved significantly over time. This review evaluates the indications, rationale and survivorship of implant options, integrating data from the British National Joint Registry (NJR), international registries and key studies. The British Joint Registry, Australian Registry and peer-reviewed study publications were reviewed to assess current practice and obtain evidence regarding shoulder arthroplasty implants including humeral head resurfacing (HHR), hemiarthroplasty, anatomic total shoulder arthroplasty (aTSA) and reverse shoulder arthroplasty (RSA). Hemiarthroplasty has limited current indications, largely being used in younger patients with preserved glenoid cartilage, and after trauma. The use of HHR has fallen dramatically. aTSA remains the gold standard for primary osteoarthritis with preserved cuff integrity. Use of RSA has expanded beyond cuff tear arthropathy, with registry data showing favourable revision rates. Whilst aTSA is still preferred for cuff-intact osteoarthritis in younger patients, and RSA remains the option for cuff arthropathy in the elderly, there is a grey area between, where the use of RSA is increasing, and evidence increasingly supports this expansion. Hemiarthroplasty and resurfacing are reserved for increasingly niche indications. Shoulder arthroplasty design is an evolving field, with convertible platforms providing adaptability to suit individual patients. Joint registry follow-up and ongoing trials are critical to improving long-term future outcomes.</div></div>","PeriodicalId":39547,"journal":{"name":"Orthopaedics and Trauma","volume":"40 3","pages":"Pages 130-138"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148153665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Orthopaedics and TraumaPub Date : 2026-06-01Epub Date: 2026-05-12DOI: 10.1016/j.mporth.2026.03.007
{"title":"Answers to the CME questions on Foot and Ankle Trauma","authors":"","doi":"10.1016/j.mporth.2026.03.007","DOIUrl":"10.1016/j.mporth.2026.03.007","url":null,"abstract":"","PeriodicalId":39547,"journal":{"name":"Orthopaedics and Trauma","volume":"40 3","pages":"Page 174"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148153974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Orthopaedics and TraumaPub Date : 2026-06-01Epub Date: 2026-05-13DOI: 10.1016/j.mporth.2026.03.003
Richard Limb, Peter Kenyon
{"title":"The evolution of the reverse total shoulder replacement","authors":"Richard Limb, Peter Kenyon","doi":"10.1016/j.mporth.2026.03.003","DOIUrl":"10.1016/j.mporth.2026.03.003","url":null,"abstract":"<div><div>The management of rotator cuff-deficient shoulders has developed significantly over time. Before the introduction of reverse total shoulder arthroplasty, treatment options for massive cuff tears, cuff tear arthropathy and complex proximal humeral fractures were restricted and could lead to poor outcomes. The reverse shoulder arthroplasty, successfully introduced by Grammont and colleagues, leveraged design features such as medialization and inferiorization of the glenohumeral centre of rotation, creation of a fixed fulcrum and recruitment of the deltoid as the primary motor of the arm, and revolutionized the treatment of these complex shoulder problems. With indications expanding, however, issues and complications such as scapular notching, instability and acromial stress fractures were observed, leading to further iterative development of design and technique. Modern developments include relative lateralization along with deltoid wrapping to enhance stability, range of motion, and implant life. This review explores the early concepts of reverse shoulder arthroplasty, outlines key biomechanical concepts, and discusses modern developments in surgical technique and strategies to mitigate complications while optimizing functional outcomes.</div></div>","PeriodicalId":39547,"journal":{"name":"Orthopaedics and Trauma","volume":"40 3","pages":"Pages 146-150"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148153667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Orthopaedics and TraumaPub Date : 2026-06-01Epub Date: 2026-06-04DOI: 10.1016/j.mporth.2026.03.006
David Limb
{"title":"Core concepts in the management of shoulder instability","authors":"David Limb","doi":"10.1016/j.mporth.2026.03.006","DOIUrl":"10.1016/j.mporth.2026.03.006","url":null,"abstract":"<div><div>Shoulder instability is a clinical problem that varies from recurrent dislocation in sporting activities to the patient who has never experienced significant shoulder trauma but cannot lift the arm above shoulder height without experiencing dislocation. This article takes a high level view of the concepts the orthopaedic trainee should understand in order to evaluate a patient and decide on appropriate treatment. These treatment methods are also considered, linking each to the concepts underpinning our understanding of instability.</div></div>","PeriodicalId":39547,"journal":{"name":"Orthopaedics and Trauma","volume":"40 3","pages":"Pages 165-171"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148153670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Orthopaedics and TraumaPub Date : 2026-06-01Epub Date: 2026-05-12DOI: 10.1016/j.mporth.2026.03.008
{"title":"CME questions on The Shoulder","authors":"","doi":"10.1016/j.mporth.2026.03.008","DOIUrl":"10.1016/j.mporth.2026.03.008","url":null,"abstract":"","PeriodicalId":39547,"journal":{"name":"Orthopaedics and Trauma","volume":"40 3","pages":"Pages 172-173"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148153671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}