中国肺癌杂志最新文献

筛选
英文 中文
[Expert Consensus on Diagnosis and Treatment of NSCLC with MET Abnormalities 
(2025 Version)]. [MET异常的NSCLC诊断和治疗专家共识(2025年版)]。
中国肺癌杂志 Pub Date : 2025-02-20 DOI: 10.3779/j.issn.1009-3419.2025.102.01
Jun Chen, Baohui Han, Yi Hu, Jian Hu
{"title":"[Expert Consensus on Diagnosis and Treatment of NSCLC with MET Abnormalities \u2029(2025 Version)].","authors":"Jun Chen, Baohui Han, Yi Hu, Jian Hu","doi":"10.3779/j.issn.1009-3419.2025.102.01","DOIUrl":"10.3779/j.issn.1009-3419.2025.102.01","url":null,"abstract":"<p><p>The mesenchymal-epithelial transition factor (MET) gene, located on human chromosome 7, plays a crucial role in the regulation of physiological processes such as cell proliferation, migration, invasion, and angiogenesis. The MET gene is one of the key drivers in non-small cell lung cancer (NSCLC), with various forms of abnormalities including MET exon 14 (METex14) skipping mutations, MET gene amplification, MET fusions, MET protein overexpression, MET activating mutations and etc. With an increasing understanding of the mechanisms underlying MET abnormalities, therapeutic strategies targeting these abnormalities have gained significant attention, and numerous studies have confirmed that NSCLC patients with MET abnormalities can derive substantial benefits from such treatments. Lung Cancer Specialty Committee of Chinese Elderly Health Care Association organized a panel of experts to provide professional recommendations on current clinical issues in the diagnosis and treatment of MET-aberrant NSCLC, combining clinical practice experiences and evidence-based medical evidences. The \"Expert Consensus on Diagnosis and Treatment of NSCLC with MET Abnormalities (2025 Version)\" has been formulated to provide standardized guidances for clinical practice in China, with the aim of optimizing the treatment outcomes.\u2029.</p>","PeriodicalId":39317,"journal":{"name":"中国肺癌杂志","volume":"28 2","pages":"81-94"},"PeriodicalIF":0.0,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11931236/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143671287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Research Progress on Molecular Subtypes and Precision Therapy 
of Pulmonary Large Cell Neuroendocrine Carcinoma].
中国肺癌杂志 Pub Date : 2025-02-20 DOI: 10.3779/j.issn.1009-3419.2025.102.06
Yuchao Feng, Xiaohong Cao
{"title":"[Research Progress on Molecular Subtypes and Precision Therapy \u2029of Pulmonary Large Cell Neuroendocrine Carcinoma].","authors":"Yuchao Feng, Xiaohong Cao","doi":"10.3779/j.issn.1009-3419.2025.102.06","DOIUrl":"10.3779/j.issn.1009-3419.2025.102.06","url":null,"abstract":"<p><p>Pulmonary large cell neuroendocrine carcinoma (LCNEC) is a high-grade neuroendocrine tumor with unique characteristics, and its treatment regimens are primarily derived from those for small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC). In recent years, the incidence rate has been on the rise, and the prognosis are affected by the interaction of multiple factors such as individual, clinical stage and treatment mode, and the heterogeneity is significant. In the study of molecular subtypes, multiple subgroups were divided according to key gene mutations such as RB1 and TP53, and genomic subtypes were associated with survival, chemotherapy response, and efficacy of precision therapy. Targeted therapy excavates multiple targets, and the efficacy of drugs is different. Immunotherapy has made remarkable progress, and immune checkpoint inhibitors (ICIs) have been effective in all stages of chemotherapy alone or in combination with chemotherapy or radiation therapy, but there is a risk of hyperprogressive diseases, and accurate prognostic markers need to be explored urgently. This review reviews the latest research progress in the study of molecular subtypes and precision therapies such as targeted therapy and immunotherapy of pulmonary LCNEC, and points out that pulmonary LCNEC treatment will develop in the direction of precision and individualization in the future.\u2029.</p>","PeriodicalId":39317,"journal":{"name":"中国肺癌杂志","volume":"28 2","pages":"146-154"},"PeriodicalIF":0.0,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11931233/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143671369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Crosstalk between Tumor Cells and Neural Signals in Neuroendocrine Carcinoma 
Metastasis: Communication Hijacking Based Perspective]. [神经内分泌癌转移中肿瘤细胞与神经信号之间的串扰:基于通讯劫持的视角]。
中国肺癌杂志 Pub Date : 2025-02-20 DOI: 10.3779/j.issn.1009-3419.2025.101.03
Shuping Song, Xinyi Wang, Siqi Zhou, Xuchen Cheng, Weixuan Lin, Yongxuan Wang, Yanqin Sun
{"title":"[Crosstalk between Tumor Cells and Neural Signals in Neuroendocrine Carcinoma \u2029Metastasis: Communication Hijacking Based Perspective].","authors":"Shuping Song, Xinyi Wang, Siqi Zhou, Xuchen Cheng, Weixuan Lin, Yongxuan Wang, Yanqin Sun","doi":"10.3779/j.issn.1009-3419.2025.101.03","DOIUrl":"10.3779/j.issn.1009-3419.2025.101.03","url":null,"abstract":"<p><p>Neuroendocrine carcinoma (NEC) represents a category of malignant tumors originating from neuroendocrine cells. Given that NEC cells exhibit characteristics of both neural and endocrine cells, they can hijack neuronal signaling pathways and dynamically regulate the expression of neuronal lineage markers during tumor metastasis, thereby constructing a microenvironment conducive to tumor growth and metastasis. Conversely, alterations in the tumor microenvironment can enhance the interactions between neurons and tumor cells, ultimately synergistically promoting the metastasis of NEC. This review highlights recent advancements in the field of cancer neuroscience, uncovering neuronal lineage markers in NEC that facilitate tumor dissemination through mediating crosstalk, bidirectional communication, and synergistic interactions between tumor cells and the nervous system. Consequently, the latest findings in tumor neuroscience have enriched our understanding of the biological mechanisms underlying tumor metastasis, opening new research avenues for a deeper comprehension of the complex biological processes involved in tumor metastasis, particularly brain metastasis. This review provides a comprehensive review of the crosstalk between tumor cells and neural signaling in the metastasis of NEC.\u2029.</p>","PeriodicalId":39317,"journal":{"name":"中国肺癌杂志","volume":"28 2","pages":"138-145"},"PeriodicalIF":0.0,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11931239/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143671278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Research Progress on Imaging Diagnosis of Non-small Cell Lung Cancer 
Which Invades Pleura or Chest Wall].
中国肺癌杂志 Pub Date : 2025-02-20 DOI: 10.3779/j.issn.1009-3419.2025.106.04
Yue Wang, Zhiyong Yuan
{"title":"[Research Progress on Imaging Diagnosis of Non-small Cell Lung Cancer \u2029Which Invades Pleura or Chest Wall].","authors":"Yue Wang, Zhiyong Yuan","doi":"10.3779/j.issn.1009-3419.2025.106.04","DOIUrl":"10.3779/j.issn.1009-3419.2025.106.04","url":null,"abstract":"<p><p>Accurate staging is the fundamental basis for the treatment and prognosis of non-small cell lung cancer (NSCLC), and whether the tumor involves the pleura or chest wall is a critical aspect in assessing the staging of peripheral lung cancer. Imaging techniques such as computed tomography (CT), magnetic resonance imaging (MRI), ultrasound (US) and positron emission tomography (PET) are widely used to determine pleural invasion in NSCLC. There has been an increasing number of studies evaluating whether NSCLC invades the pleura and the extent of such invasion. This article provides a review of the staging and the imaging diagnostic criteria of pleural invasion, aiming to offer references for peers in the precise diagnosis of pleural or chest wall invasion.\u2029.</p>","PeriodicalId":39317,"journal":{"name":"中国肺癌杂志","volume":"28 2","pages":"131-137"},"PeriodicalIF":0.0,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11931234/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143671363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Exploration of the Predictive Value of Peripheral Blood-related Indicators for EGFR 
Mutations and Prognosis in Non-small Cell Lung Cancer Using Machine Learning]. [利用机器学习探索外周血相关指标对非小细胞肺癌表皮生长因子受体突变和预后的预测价值]。
中国肺癌杂志 Pub Date : 2025-02-20 DOI: 10.3779/j.issn.1009-3419.2025.102.05
Shulei Fu, Shaodi Wen, Jiaqiang Zhang, Xiaoyue Du, Ru Li, Bo Shen
{"title":"[Exploration of the Predictive Value of Peripheral Blood-related Indicators for EGFR \u2029Mutations and Prognosis in Non-small Cell Lung Cancer Using Machine Learning].","authors":"Shulei Fu, Shaodi Wen, Jiaqiang Zhang, Xiaoyue Du, Ru Li, Bo Shen","doi":"10.3779/j.issn.1009-3419.2025.102.05","DOIUrl":"10.3779/j.issn.1009-3419.2025.102.05","url":null,"abstract":"<p><strong>Background: </strong>Epidermal growth factor receptor (EGFR) sensitive mutation is one of the effective targets of targeted therapy for non-small cell lung cancer (NSCLC). However, due to the difficulty of obtaining some primary tissues and the economic factors in some underdeveloped areas, some patients cannot undergo traditional genetic testing. The aim of this study is to establish a machine learning (ML) model using non-invasive peripheral blood markers to explore the biomarkers closely related to EGFR mutation status in NSCLC and evaluate their potential prognostic value.</p><p><strong>Methods: </strong>2642 lung cancer patients who visited Jiangsu Cancer Hospital from November 2016 to May 2023 were retrospectively enrolled and finally 175 NSCLC patients with complete follow-up data were included in the study. The ML model was constructed based on peripheral blood indicators and divided into training set and test set according to the ratio of 8:2. Unsupervised learning algorithms were used for clustering blood features and mutual information method for feature selection, and an ensemble learning algorithm based on Shapley value was designed to calculate the contribution of each feature to the model prediction result. The receiver operating characteristic (ROC) curve was used to evaluate the predictive ability of the model.</p><p><strong>Results: </strong>Through the feature extraction and contribution analysis of the predictive results of the interpretable ML model based on the Shapley value, the top ten indicators with the highest contribution were: pathological type, phosphorus, eosinophils, monocyte count, activated partial thromboplastin time, potassium, total bilirubin, sodium, eosinophil percentage, and total cholesterol. The area under the curve (AUC) of the model was 0.80. In addition, patients with hyponatremia and squamous cell carcinoma group had a poor prognosis (P<0.05).</p><p><strong>Conclusions: </strong>The interpretable model constructed in this study provides a new approach for the prediction of EGFR mutation status in NSCLC patients, which provides a scientific basis for the diagnosis and treatment of patients who cannot undergo genetic testing.</p>","PeriodicalId":39317,"journal":{"name":"中国肺癌杂志","volume":"28 2","pages":"105-113"},"PeriodicalIF":0.0,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11931235/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143671292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Chinese Expert Consensus on Assessment and Clinical Application of 
Tertiary Lymphoid Structure for Non-small Cell Lung Cancer (2025 Version)].
中国肺癌杂志 Pub Date : 2025-02-20 DOI: 10.3779/j.issn.1009-3419.2025.102.03
{"title":"[Chinese Expert Consensus on Assessment and Clinical Application of \u2029Tertiary Lymphoid Structure for Non-small Cell Lung Cancer (2025 Version)].","authors":"","doi":"10.3779/j.issn.1009-3419.2025.102.03","DOIUrl":"10.3779/j.issn.1009-3419.2025.102.03","url":null,"abstract":"<p><p>The tertiary lymphoid structure (TLS) plays a crucial role in the tumor microenvironment, influencing tumor development and progression. As an emerging biomarker for predicting the prognosis and treatment response in cancer patients, TLS has received increasing attention. However, there is currently a lack of standardized evaluation criteria for TLS, and significant differences exist in TLS across different tumor tissues. This poses challenges for the clinical application of this biomarker in translation. To meet the clinical diagnosis and treatment needs of non-small cell lung cancer (NSCLC), this consensus focuses on the definition, clinical significance, testing components, and assessment methods of TLS in NSCLC. Combining relevant research and Chinese clinical practice, it provides standardized and normalized suggestions for the clinical assessment and application of TLS, so as to improve the understanding of TLS among clinicians and pathologists, and provide a reference basis for the clinical application of the detection of TLS in NSCLC. \u2029.</p>","PeriodicalId":39317,"journal":{"name":"中国肺癌杂志","volume":"28 2","pages":"95-104"},"PeriodicalIF":0.0,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11931240/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143671355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Epithelial-mesenchymal Transition: Biological Basis and Clinical Prospects 
of Lung Cancer Invasion, Metastasis, and Drug Resistance].
中国肺癌杂志 Pub Date : 2025-02-20 DOI: 10.3779/j.issn.1009-3419.2025.102.07
Hengxing Sun, Mengting Xiong, Shuanshuan Xie, Jing Wen
{"title":"[Epithelial-mesenchymal Transition: Biological Basis and Clinical Prospects \u2029of Lung Cancer Invasion, Metastasis, and Drug Resistance].","authors":"Hengxing Sun, Mengting Xiong, Shuanshuan Xie, Jing Wen","doi":"10.3779/j.issn.1009-3419.2025.102.07","DOIUrl":"10.3779/j.issn.1009-3419.2025.102.07","url":null,"abstract":"<p><p>Lung cancer is the leading cause of cancer-related deaths worldwide, characterized by high incidence and mortality rates. The primary reasons for treatment failure in lung cancer patients are tumor invasion and drug resistance, particularly resistance to chemotherapeutic agents and epidermal growth factor receptor (EGFR) mutant targeted therapy, which considerably undermine the therapeutic outcomes for those with advanced lung cancer. Epithelial-mesenchymal transition (EMT) serves as a crucial biological process closely associated with physiological or pathological processes such as tissue embryogenesis, organogenesis, wound repair, and tumor invasion. Numerous studies have indicated that EMT, mediated through various signaling pathways, plays a pivotal role in the initiation, progression, and metastasis of lung cancer, while it is also closely associated with drug resistance in lung cancer cells. Therefore, research focusing on the molecular mechanisms and pathophysiology related to EMT can contribute to reversing drug resistance in drug treatment for lung cancer, thereby improving prognosis. This article reviews the progress in research on EMT in the invasion, metastasis, and drug resistance of lung cancer based on relevant domestic and international literature.</p>","PeriodicalId":39317,"journal":{"name":"中国肺癌杂志","volume":"28 2","pages":"155-164"},"PeriodicalIF":0.0,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11931237/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143671282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[FCN3 Can Serve as A Potential Biomarker for Prognosis and 
Immunotherapy of Lung Squamous Cell Carcinoma]. [FCN3可作为肺鳞癌预后和免疫疗法的潜在生物标记物】。]
中国肺癌杂志 Pub Date : 2025-02-20 DOI: 10.3779/j.issn.1009-3419.2025.105.01
Wei Li, Lingling Zu, Song Xu
{"title":"[FCN3 Can Serve as A Potential Biomarker for Prognosis and \u2029Immunotherapy of Lung Squamous Cell Carcinoma].","authors":"Wei Li, Lingling Zu, Song Xu","doi":"10.3779/j.issn.1009-3419.2025.105.01","DOIUrl":"10.3779/j.issn.1009-3419.2025.105.01","url":null,"abstract":"<p><strong>Background: </strong>Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related deaths worldwide. Lung squamous cell carcinoma (LUSC) is an important pathological subtype of NSCLC. The complex immune escape mechanism limits the effectiveness of immunotherapy. Ficolin-3 (FCN3) is a crucial immunomodulatory molecule that regulates immune escape by remodeling the tumor microenvironment. However, the role of FCN3 in LUSC remains unclear. This study employed bioinformatics methods to analyze LUSC samples from The Cancer Genome Atlas (TCGA) database. The aim of this study was to explore the potential biological functions and prognostic significance of FCN3 in LUSC.</p><p><strong>Methods: </strong>A pan-cancer analysis characterized the expression patterns and prognostic value of FCN3 across various cancer types. Simultaneously, the expression patterns of FCN3 in LUSC samples from the TCGA database and its relationship with prognosis were analyzed. The Nomogram model and somatic mutation analysis, differential expression analysis, correlation analysis, as well as Gene Ontology (GO), Kyoto Encyclopedia of Genes and Genomes (KEGG), and Gene Set Enrichment Analysis (GSEA) were constructed to explore the potential mechanisms of FCN3. Additionally, immune infiltration analysis, immune escape score (TIDE), and correlation analysis of immune-related molecules were used to reveal the regulatory role of high FCN3 levels on immunity in LUSC. Furthermore, the correlation between FCN3 expression characteristics and drug sensitivity was evaluated. Finally, in vitro experiments verified the expression characteristics of FCN3 in LUSC.</p><p><strong>Results: </strong>The expression level of FCN3 in LUSC tissues was significantly lower than that in normal tissues. Patients with high FCN3 expression in LUSC had a poorer prognosis compared to those with low expression. Different expression levels of FCN3 were associated with the abundance of immune cell infiltration and immune cell dysfunction. It was also linked to the expression of immune checkpoints, immune stimulatory molecules, major histocompatibility complex (MHC) class molecules, and chemotherapy drug sensitivity.</p><p><strong>Conclusions: </strong>High expression of FCN3 in LUSC is associated with poor prognosis and is linked to immune cell infiltration, immune-related pathways, and immune-related molecules. FCN3 may be a potential prognostic marker and a new target for immunotherapy in LUSC.</p>","PeriodicalId":39317,"journal":{"name":"中国肺癌杂志","volume":"28 2","pages":"114-130"},"PeriodicalIF":0.0,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11931238/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143671295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Clinical Practice Guidelines for the Management of Brain Metastases from 
Non-small Cell Lung Cancer with Actionable Gene Alterations in China (2025 Edition)].
中国肺癌杂志 Pub Date : 2025-01-20 Epub Date: 2025-01-07 DOI: 10.3779/j.issn.1009-3419.2024.102.42
{"title":"[Clinical Practice Guidelines for the Management of Brain Metastases from \u2029Non-small Cell Lung Cancer with Actionable Gene Alterations in China (2025 Edition)].","authors":"","doi":"10.3779/j.issn.1009-3419.2024.102.42","DOIUrl":"10.3779/j.issn.1009-3419.2024.102.42","url":null,"abstract":"<p><p>Brain metastasis has emerged as a significant challenge in the comprehensive management of patients with non-small cell lung cancer (NSCLC), particularly in those harboring driver gene mutations. Traditional treatments such as radiotherapy and surgery offer limited clinical benefits and are often accompanied by cognitive dysfunction and a decline in quality of life. In recent years, novel small molecule tyrosine kinase inhibitors targeting epidermal growth factor receptor (EGFR), anaplastic lymphoma kinase (ALK), and other pathways have been developed, effectively penetrating the blood-brain barrier while enhancing intracranial drug concentrations and improving patient outcomes. This advancement has transformed the treatment landscape for brain metastases in NSCLC. Consequently, the Lung Cancer Medical Education Committee of the Chinese Medical Education Association and the Brain Metastasis Collaboration Group of the Lung Cancer Youth Expert Committee of the Beijing Medical Reward Foundation have jointly initiated and formulated the Clinical Practice Guidelines for the Management of Brain Metastases from Non-small Cell Lung Cancer with Actionable Gene Alterations in China (2025 Edition). This guideline integrates the latest research findings with clinical experience, adhering to multidisciplinary treatment principles, and encompasses aspects such as diagnosis, timing of intervention, and systemic and local treatment options for driver gene positive NSCLC brain metastases. Additionally, it proposes individualized treatment strategies tailored to different driver gene types, aiming to provide clinicians with a reference to enhance the overall diagnostic and therapeutic standards for NSCLC brain metastases in China.\u2029.</p>","PeriodicalId":39317,"journal":{"name":"中国肺癌杂志","volume":"28 1","pages":"1-21"},"PeriodicalIF":0.0,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11848629/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143484396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Application Research of Narrative Care to the Management of Symptom Clusters 
and Post-traumatic Growth in Patients Undergoing Lung Cancer Surgery].
中国肺癌杂志 Pub Date : 2025-01-20 DOI: 10.3779/j.issn.1009-3419.2024.102.44
Xinxing Sun, Yalin Wang, Wang Lv, Linhai Zhu
{"title":"[Application Research of Narrative Care to the Management of Symptom Clusters \u2029and Post-traumatic Growth in Patients Undergoing Lung Cancer Surgery].","authors":"Xinxing Sun, Yalin Wang, Wang Lv, Linhai Zhu","doi":"10.3779/j.issn.1009-3419.2024.102.44","DOIUrl":"10.3779/j.issn.1009-3419.2024.102.44","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Narrative care is emerging as a new discipline to achieve high-quality nursing. It can be seen in clinical studies on improving the management of schizophrenia, depression and chronic diseases, but its application in surgical patients with lung cancer is rarely reported. The aim of this study was to study the effect on improving symptom cluster management and post-traumatic growth of surgical patients through narrative care model, and to explore its clinical advantages in promoting physical and mental rehabilitation of lung cancer patients.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;A total of 82 patients with lung cancer who underwent surgical treatment in the First Affiliated Hospital of Zhejiang University from July 2024 to October 2024 were selected as the study objects by convenience sampling, and randomly divided into the control group and observation group according to random number method, with 41 cases in each group. The control group received routine nursing; On this basis, the observation group was integrated into three consecutive narrative nursing sessions on the day of admission, 3 days after surgery and 1 week after surgery. After collecting the general data of the patients before intervention, the Generalized Anxiety Scale, the Pittsburgh Sleep Quality Index, the Chinese Version of the Lung Cancer Patients Quality of Life Assessment Scale and the Chinese Version of the Post-traumatic Growth Assessment Scale were used. After each narrative intervention, the two groups of patients were assessed again, and the scores of the two groups were compared at the three stages.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;The scores of anxiety, sleep, quality of life and post-traumatic growth level of the patients on the 3 days and 1 week postoperatively were better in the observation group than in the control group, and the differences were all statistically significant (P&lt;0.05). In addition, the results within the groups showed that the anxiety scores of the observation group and the control group gradually decreased in the preoperative period, 3 days and 1 week postoperatively; the post-traumatic growth scores gradually increased in the preoperative period, 3 days and 1 week postoperatively; however, due to the stress of the surgery and postoperative discomfort, the sleep scores of the patients of the two groups on 3 days postoperatively were higher than those in the preoperative period and 1 week postoperatively, and the sleep scores of the patients of 1 week postoperatively were significantly lower than those in the preoperative period; and the quality of life of the patients on the 3 days postoperatively scores were lower than preoperative period and 1 week postoperatively, and the quality of survival scores in 1 week postoperatively were higher than the preoperative period, and the differences were statistically significant (P&lt;0.05).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;The application of narrative nursing to lung cancer surgery","PeriodicalId":39317,"journal":{"name":"中国肺癌杂志","volume":"28 1","pages":"40-46"},"PeriodicalIF":0.0,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11848649/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143484392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信