Journal of Nepal Paediatric Society最新文献_第3页

Incidence of Birth Defects among Live Born Neonates at Tertiary Level Maternity Hospital in Nepal 尼泊尔三级妇产医院活产新生儿出生缺陷发生率

Journal of Nepal Paediatric Society Pub Date : 2022-12-31 DOI: 10.3126/jnps.v42i2.41093

Shristi Shakya, Kalpana Upadhaya Subedi, Megha Mishra

{"title":"Incidence of Birth Defects among Live Born Neonates at Tertiary Level Maternity Hospital in Nepal","authors":"Shristi Shakya, Kalpana Upadhaya Subedi, Megha Mishra","doi":"10.3126/jnps.v42i2.41093","DOIUrl":"https://doi.org/10.3126/jnps.v42i2.41093","url":null,"abstract":"Introduction: Birth defects are structural and functional anomalies that present before, at birth, or later in life. This study aimed to find out total incidence, type of structural birth defects in live born babies in Nepal.\u0000Methods: The study was conducted at a tertiary level maternity hospital in Nepal from 14 April 2018 to 13 April 2019. Data was collected on online Newborn Birth Defect data base developed by WHO South- East-Asia Regional Office. All live born babies with external and internal birth defects confirmed by radiographic, ultrasonography and echocardiography until seven days of life were included. Ethical approval was obtained from Institutional Review Committee of hospital.\u0000Results: Total of 21,564 live babies were delivered during one-year study period. Out of these, 220 (1.02%) had one or more birth defects. Number of male babies {130 (59%)} were more than female {89 (40.9%)}. 176 (80%) babies with the malformation were born to mother within age group 20 to 35 years. Of the total 220 babies with birth defects, 197 (89.5%) had isolated malformations and remaining 23 (10.4%) had sequence malformations. The most frequent malformations involved cardiovascular system 125 (56.8%) followed by gastrointestinal system 37 (16.8%), musculoskeletal system 34 (15.4%) and central nervous system 18 (8.1%).\u0000Conclusions: Incidence of overall birth defects in this study was found to be 1.02% in which cardiovascular system anomalies was the most common followed by gastrointestinal, musculoskeletal and central nervous system anomalies.","PeriodicalId":39140,"journal":{"name":"Journal of Nepal Paediatric Society","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49420677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correlation of cord Blood pH with Nucleated RBC and Serum LDH in Neonates with Perinatal Asphyxia 围产期窒息新生儿脐血pH值与有核红细胞和血清LDH的相关性

Journal of Nepal Paediatric Society Pub Date : 2022-12-31 DOI: 10.3126/jnps.v42i3.46876

Chiranth S B, K. Avabratha

{"title":"Correlation of cord Blood pH with Nucleated RBC and Serum LDH in Neonates with Perinatal Asphyxia","authors":"Chiranth S B, K. Avabratha","doi":"10.3126/jnps.v42i3.46876","DOIUrl":"https://doi.org/10.3126/jnps.v42i3.46876","url":null,"abstract":"Introduction: Perinatal asphyxia is one of the leading causes of neonatal mortality in developing countries. No single indicator has good diagnostic efficacy for perinatal asphyxia and only a combination of various indices may help in diagnosis. This study aims at determining the utility of serum lactate dehydrogenase (LDH) and cord blood nucleated red blood cell (nRBC) count as surrogate markers to pH in perinatal asphyxia.\u0000Methods: It is an observational study done over a period of 18 months. All newborn babies fitting into inclusion criteria were enrolled into the study. After initial resuscitation, cord blood was sent for pH and nRBC analysis and serum LDH levels was estimated from first collected blood sample (within six hours). Data was collected on excel sheet, Pearson’s correlation coefficients and ROC curves were used to tabulate results.\u0000Results: Our study included 74 neonates with perinatal asphyxia. Mean pH was 6.99 (SD - 0.138). Mean nRBC count was 38 / 100 WBC (SD17.9) and mean LDH level was 1478 IU / L (SD - 429). Cord blood pH showed significant (p < 0.001) correlation with raising nRBC count and LDH levels ROC plot showed nRBC count (AUC: 0.7866) and Serum LDH (AUC: 0.8143) as very good predictors of severe acidosis in perinatal asphyxia.\u0000Conclusions: Cord blood nRBC count and serum LDH levels are significantly increased in perinatal asphyxia and correlate well with severity of acidosis. Nucleated RBC count and serum LDH can be used as surrogate markers to diagnose perinatal asphyxia.","PeriodicalId":39140,"journal":{"name":"Journal of Nepal Paediatric Society","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49647416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Serum Homocysteine Levels in Indian Children on Valproate Monotherapy 丙戊酸钠单药治疗印度儿童血清同型半胱氨酸水平

Journal of Nepal Paediatric Society Pub Date : 2022-12-31 DOI: 10.3126/jnps.v42i3.45540

S. Swaroop, Medha Mittal, Smita Nair, Reetika Saini, J. Bagla

引用次数: 0

Knowledge and Attitude of Nurses on Implementation of Atraumatic Care among Hospitalized Children in Eastern Nepal: A Cross-sectional Study 尼泊尔东部住院儿童实施创伤后护理的护士知识和态度的横断面研究

Journal of Nepal Paediatric Society Pub Date : 2022-12-31 DOI: 10.3126/jnps.v42i3.46172

Pramila Mahato, Rit Shrestha, B. K. Karn, Amit Kumar Chaudhary, Rakesh Singh

{"title":"Knowledge and Attitude of Nurses on Implementation of Atraumatic Care among Hospitalized Children in Eastern Nepal: A Cross-sectional Study","authors":"Pramila Mahato, Rit Shrestha, B. K. Karn, Amit Kumar Chaudhary, Rakesh Singh","doi":"10.3126/jnps.v42i3.46172","DOIUrl":"https://doi.org/10.3126/jnps.v42i3.46172","url":null,"abstract":"Introduction: The modality and quality of care received during hospitalization affects a child’s response to their illness. Thus, any intervention delivered by healthcare providers including nurses must be based on principles of atraumatic care. This study aims to assess the knowledge and attitude of nurses in the implementation of atraumatic care among hospitalized children in a tertiary care center in Eastern Nepal.\u0000Methods: A descriptive cross-sectional study was conducted among 106 nurses in a tertiary hospital from 4th January to 1st February 2020. Ethical approval was received from the Institutional Review Committee. Sampling was done by total population enumeration method. Data was collected using a self-administered three-part questionnaire and analyzed using Statistical Package for the Social Sciences version 11.5 by utilizing descriptive statistics.\u0000Results: The mean knowledge and attitude of nurses towards implementation of atraumatic care among hospitalized children was found to be 14.90 ± 3.90 and 74.74 ± 7.5 respectively. Out of 106 nurses, 73 (68.90%) had adequate knowledge whereas 56 (52.80%) had favorable attitudes towards principles and implementation of atraumatic care, assessed using reliable scales. Variations due to socio-demographic and professional parameters were insignificant.\u0000Conclusions: The study shows that majority of the surveyed nurses had adequate knowledge of the principles of atraumatic care and a favorable attitude towards its application among hospitalized children. However, the measured attitude of nursing practitioners was relatively lower in terms of favorability.","PeriodicalId":39140,"journal":{"name":"Journal of Nepal Paediatric Society","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46848779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Medical Undergraduate Students’ Viewpoint on Online Learning During COVID-19 Pandemic 新冠肺炎疫情下医学本科学生在线学习的看法

Journal of Nepal Paediatric Society Pub Date : 2022-12-31 DOI: 10.3126/jnps.v42i3.46062

Ekansh Rathoria, Richa Rathoria, Umang Singal, Asheesh Pratap Singh, Utkarsh Bansal, Prashant Agrawal

{"title":"Medical Undergraduate Students’ Viewpoint on Online Learning During COVID-19 Pandemic","authors":"Ekansh Rathoria, Richa Rathoria, Umang Singal, Asheesh Pratap Singh, Utkarsh Bansal, Prashant Agrawal","doi":"10.3126/jnps.v42i3.46062","DOIUrl":"https://doi.org/10.3126/jnps.v42i3.46062","url":null,"abstract":"Introduction: The coronavirus pandemic constrained medical colleges to discontinue face-to-face learning activities and suddenly switch to an online learning model. Technology is making its way into medical education, also being advocated by the medical commission, though students’ perception is still poorly understood. This study aimed to investigate the medical students’ perspectives on online learning.\u0000Methods: It was a cross-sectional, questionnaire-based study to assess the demographics, merits, demerits, recommendations, and suggestions for online learning by medical undergraduates. A combination of multiplechoice, Likert scale-based, and open-ended questions was used.\u0000Results: The student-perceived merits of e-learning were flexibility in timings, convenience, self-directed learning approach, and prevention of pandemic spread. The demerits viewed were lack of personal interaction with teacher and batchmates, increased distractions, lack of high-speed internet, and less / no hands-on experience. The classroom teaching was the favoured teaching method (45.7%) and easy to comprehend (55.8%). The recommendations included: medical curriculum should not be completely e-learning based (84.1%), training for using online applications (51.4%), providing high-speed internet and apps with no time limit (83.7%), taking online tests (64.4%), student’s feedback (75%), and frequent online demonstrations and simulations (64.9%). Overall, 52.4% of students’ morale was positive towards e-learning. Students rated blended teaching as the preferred teaching method.\u0000Conclusions: Medical students still prefer face-to-face learning and opted for blended learning over complete e-learning. Appropriate steps like training faculties, providing high-speed internet, taking formative tests, giving online demonstrations, involving simulations, and student feedback can improve e-learning quality.","PeriodicalId":39140,"journal":{"name":"Journal of Nepal Paediatric Society","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42783118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Less Invasive Surfactant Administration (LISA) in Premature Neonates, using 5F feeding tube versus 2 mm Endotracheal tube – An Innovative, Pilot study 早产新生儿使用5F饲管与2mm气管插管的微创表面活性剂给药（LISA）——一项创新的试点研究

Journal of Nepal Paediatric Society Pub Date : 2022-12-31 DOI: 10.3126/jnps.v42i2.40619

K. Konda, Swapna Lingaldinna, Sadiqua Anjum, M. Alimelu, Himabindu Singh, Apoorva Tadury

{"title":"Less Invasive Surfactant Administration (LISA) in Premature Neonates, using 5F feeding tube versus 2 mm Endotracheal tube – An Innovative, Pilot study","authors":"K. Konda, Swapna Lingaldinna, Sadiqua Anjum, M. Alimelu, Himabindu Singh, Apoorva Tadury","doi":"10.3126/jnps.v42i2.40619","DOIUrl":"https://doi.org/10.3126/jnps.v42i2.40619","url":null,"abstract":"Introduction: Administration of LISA using thin and soft catheters like 5 F orogastric tube, though less invasive, is technically challenging and needs expertise. We hypothesized, use of a 2 mm Endotracheal (ET) tube for administration of LISA could be an easy and convenient alternative.\u0000 Methods: This is a prospective, single-centric, quasi-random, pilot trial conducted in the inborn unit of a tertiary care hospital from May 2020 - December 2020. All the inborn preterm (28 - 34 weeks) neonates with respiratory distress requiring surfactant were alternately allocated to receive LISA using a 5 F infant feeding tube or an uncuffed 2.0 size ET tube. The primary outcome was successful administration of surfactant defined as a procedure without any need for positive pressure ventilation.\u0000Results: In our study, 25 neonates were enrolled in each arm. Administration of LISA using 2 mm ET tube was associated with better success of surfactant administration with lesser incidence of PPV (20 vs 11, p < 0.05), desaturation (5 vs 12, p < 0.05), and bradycardia (3 vs 10, p < 0.05) compared to LISAOG.\u0000Conclusions: Administration of LISA using a 2 mm ET is an easily adaptable and convenient alternative that is well tolerated by the neonates without any adverse effects.","PeriodicalId":39140,"journal":{"name":"Journal of Nepal Paediatric Society","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49299647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Guillain Barre Syndrome as a Presentation of post Covid-19 Infection among Children: A Case Series 格林-巴利综合征作为儿童Covid-19后感染的一种表现:一个病例系列

Journal of Nepal Paediatric Society Pub Date : 2022-12-31 DOI: 10.3126/jnps.v42i3.45157

Kavthekar Saiprasad Onkareshwar, Patil Rahul Ravso, Narahari Venkata Susmitha, Jadhav Vilas Maruti, Patil Nivedita Balasaheb, Kurane Anil Bapurao

引用次数: 0

Incidence, Outcome and Predictors of Mortality in Respiratory distress syndrome (RDS): A Prospective Cohort Study at Tertiary Care Hospital in Nepal 呼吸窘迫综合征(RDS)的发病率、结局和死亡率预测因素:尼泊尔三级医院的前瞻性队列研究

Journal of Nepal Paediatric Society Pub Date : 2022-12-31 DOI: 10.3126/jnps.v42i2.44318

S. Basnet, Surabhi Aryal, L. Shrestha

{"title":"Incidence, Outcome and Predictors of Mortality in Respiratory distress syndrome (RDS): A Prospective Cohort Study at Tertiary Care Hospital in Nepal","authors":"S. Basnet, Surabhi Aryal, L. Shrestha","doi":"10.3126/jnps.v42i2.44318","DOIUrl":"https://doi.org/10.3126/jnps.v42i2.44318","url":null,"abstract":"Introduction: With advances in therapies during antenatal and perinatal period, there has been apparent decrease in incidence and mortality due to respiratory distress syndrome (RDS). However, there is paucity of data on exact incidence and outcome of RDS in resource limited setting. This study was conducted with the primary aim to describe the outcome of RDS and analyze the predictors for mortality.\u0000Methods: A prospective observational study was conducted in the Neonatal Intensive Care Unit (NICU) and Neonatal Unit of Tribhuvan University Teaching Hospital (TUTH), Kathmandu, Nepal from October 2019 to April 2021.\u0000Results: A total of 94 preterm newborns developed RDS giving prevalence of 20.5 per 1000 live birth cohort at TUTH. Incidence of RDS among preterm babies was 14.6%. The median duration of continuous positive airway pressure (CPAP) was 48 hours (Range 8 - 192 hours). Inhospital mortality rate was 15 (15.96%). Lower gestational age and premature rupture of membrane (PROM) were significantly associated with higher mortality whereas Normal Vaginal delivery (NVD) was associated with lower mortality. Logistic regression analysis for risk of dying for the cohort predicted that lower birth weight (AOR = 0.99; 95% CI = 0.99 - 0.99; P = 0:01), sepsis (AOR = 145.14; 95% CI = 5.04 - 4175.15; P = 0:004) are independently associated with increased risk of dying whereas increase duration of NICU stay decreased the risk (AOR = 0.71; 95% CI = 0.54 - 0.91; P = 0:01).\u0000 Conclusions: The mortality rate decreases with increasing gestational age and birth weight. A number of neonatal factors, either in isolation or in combination, were significantly associated with in-hospital mortality","PeriodicalId":39140,"journal":{"name":"Journal of Nepal Paediatric Society","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45668135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Congenital Chylothorax as a Cause of Non Immune Hydrops: A Case Report 先天性乳糜胸致非免疫性水疱1例

Journal of Nepal Paediatric Society Pub Date : 2022-12-31 DOI: 10.3126/jnps.v42i2.39150

Sunita Arora, G. Narang, Anmol Kaur, T. Kaur

引用次数: 0

A Novel Strategy for Umbilical Granuloma Removal: Cutting off with a Nylon Suture Thread 一种新的去除脐带颗粒瘤的策略：用尼龙缝线切断

Journal of Nepal Paediatric Society Pub Date : 2022-12-31 DOI: 10.3126/jnps.v42i3.45499

Kazuto Taniguchi, Kazutaka Mizuta, Kazuyasu Uemichi

引用次数: 0