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Hacettepe University Journal of the Faculty of Pharmacy最新文献

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Design, Synthesis and Antimycobacterial Activity of 2-(Benzimidazol-2-yl)-propanenitrile Analogs 2-(苯并咪唑-2-基)-丙腈类似物的设计、合成及抑菌活性研究
Hacettepe University Journal of the Faculty of Pharmacy Pub Date : 2022-03-31 DOI: 10.52794/hujpharm.1029943
Oya Unsal Tan, Mustafa Mert Sirim, S. K. Vagolu, Sriram Dharmarajan
{"title":"Design, Synthesis and Antimycobacterial Activity of 2-(Benzimidazol-2-yl)-propanenitrile Analogs","authors":"Oya Unsal Tan, Mustafa Mert Sirim, S. K. Vagolu, Sriram Dharmarajan","doi":"10.52794/hujpharm.1029943","DOIUrl":"https://doi.org/10.52794/hujpharm.1029943","url":null,"abstract":"","PeriodicalId":39138,"journal":{"name":"Hacettepe University Journal of the Faculty of Pharmacy","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80584015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prospects for the search for new biologically active compounds among the derivatives of the heterocyclic system of 1,2,4-triazole. 1,2,4-三唑杂环系衍生物中寻找新的生物活性化合物的展望。
Hacettepe University Journal of the Faculty of Pharmacy Pub Date : 2022-03-30 DOI: 10.52794/hujpharm.1019625
Yurii Sameliuk, A. Kaplaushenko, Natalia Nedorezaniuk, Liusine Ostretsova, Feodosiia Di̇akova, B. Gutyj
{"title":"Prospects for the search for new biologically active compounds among the derivatives of the heterocyclic system of 1,2,4-triazole.","authors":"Yurii Sameliuk, A. Kaplaushenko, Natalia Nedorezaniuk, Liusine Ostretsova, Feodosiia Di̇akova, B. Gutyj","doi":"10.52794/hujpharm.1019625","DOIUrl":"https://doi.org/10.52794/hujpharm.1019625","url":null,"abstract":"The authors are not native speakers of Turkish \u0000 \u0000The purpose of this literature review was to systematize data from studies of the biological activity of 1,2,4-triazole derivatives with substituents in positions 4 and 5. The authors set the task of forming an idea of current directions in the selection of substitutions for 1,2,4-triazole based on research. \u0000As a result of the study, 75 literature sources were analyzed. This made it possible to form a further vector in terms of searching for biologically active structures among 1,2,4-triazole derivatives. The review develops a modern approach to the search for biologically active substances among 1,2,4-triazole derivatives. Systematized data on the nature of substituents in the core of 1,2,4-triazole, which affect a specific type of activity. \u0000The search material was selected over the past decade with the highest number of citations at the time of literature analysis.","PeriodicalId":39138,"journal":{"name":"Hacettepe University Journal of the Faculty of Pharmacy","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87946033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
Melazma Tedavisinde Güncel Yaklaşımlar Ve Olası Toksik Etkileri
Hacettepe University Journal of the Faculty of Pharmacy Pub Date : 2022-03-01 DOI: 10.52794/hujpharm.1005810
Hülya Tezel, Aylin Balci, Pınar Erkekoğlu
{"title":"Melazma Tedavisinde Güncel Yaklaşımlar Ve Olası Toksik Etkileri","authors":"Hülya Tezel, Aylin Balci, Pınar Erkekoğlu","doi":"10.52794/hujpharm.1005810","DOIUrl":"https://doi.org/10.52794/hujpharm.1005810","url":null,"abstract":"","PeriodicalId":39138,"journal":{"name":"Hacettepe University Journal of the Faculty of Pharmacy","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73165503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
SIÇANLARDA TIKANMA SARILIĞINDA MELATONİN VE N-ASETİLSİSTEİNİN ETKİLERİ
Hacettepe University Journal of the Faculty of Pharmacy Pub Date : 2022-02-22 DOI: 10.52794/hujpharm.1034938
Mehmet Fatih Eki̇ci̇, Alper Akcan, H. Akyildiz, Kemalettin Deni̇z, Recep Saraymen, Yücel Aritaş
{"title":"SIÇANLARDA TIKANMA SARILIĞINDA MELATONİN VE N-ASETİLSİSTEİNİN ETKİLERİ","authors":"Mehmet Fatih Eki̇ci̇, Alper Akcan, H. Akyildiz, Kemalettin Deni̇z, Recep Saraymen, Yücel Aritaş","doi":"10.52794/hujpharm.1034938","DOIUrl":"https://doi.org/10.52794/hujpharm.1034938","url":null,"abstract":"","PeriodicalId":39138,"journal":{"name":"Hacettepe University Journal of the Faculty of Pharmacy","volume":"231 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76108607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation Of Antioxidant Activity Of 1, 2, 4-Triazole Derivatives With Morpholine Moiety 含Morpholine基团的1,2,4 -三唑衍生物的抗氧化活性评价
Hacettepe University Journal of the Faculty of Pharmacy Pub Date : 2022-02-08 DOI: 10.52794/hujpharm.1033112
R. Shcherbyna, Yevhen S. Pruhlo, M. Duchenko, Mariia A. Kulagina, V. Kudria, Vashchuk Valentyna
{"title":"Evaluation Of Antioxidant Activity Of 1, 2, 4-Triazole Derivatives With Morpholine Moiety","authors":"R. Shcherbyna, Yevhen S. Pruhlo, M. Duchenko, Mariia A. Kulagina, V. Kudria, Vashchuk Valentyna","doi":"10.52794/hujpharm.1033112","DOIUrl":"https://doi.org/10.52794/hujpharm.1033112","url":null,"abstract":"","PeriodicalId":39138,"journal":{"name":"Hacettepe University Journal of the Faculty of Pharmacy","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90912801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
PPublic Health Impacts of Exposure to Disinfectants, Therapeutics, and Illicit Substances During the COVID-19 Pandemic COVID-19大流行期间接触消毒剂、治疗药物和非法物质对公共卫生的影响
Hacettepe University Journal of the Faculty of Pharmacy Pub Date : 2022-02-07 DOI: 10.52794/hujpharm.978727
R. Reis, E. Çöldür
{"title":"PPublic Health Impacts of Exposure to Disinfectants, Therapeutics, and Illicit Substances During the COVID-19 Pandemic","authors":"R. Reis, E. Çöldür","doi":"10.52794/hujpharm.978727","DOIUrl":"https://doi.org/10.52794/hujpharm.978727","url":null,"abstract":"The SARS-CoV-2 virus spread rapidly, infecting over a hundred million people worldwide;thus, it has been called the COVID-19 pandemic, in which it is very important to wear a protective mask, wash hands properly, obey social distance rules, and use disinfectants to protect ourselves against infection. Therefore, the consumption of cleaning agents such as disinfectants, surface cleaners, and bleach has increased during the pandemic. Misuse of these substances such as drinking or gargling of cleaners and excessive use has led to many poisoning cases and even deaths. In addition, quarantine and stay-at-home orders during the pandemic caused people to could not socialize and feel dissociated. Moreover, due to the economic problems, many people became unemployed, which affected substance abuse and alcohol consumption frequency, thus poisoning cases as well. This article aimed to review how the COVID-19 was affected the disinfectant or cleaner-induced poisoning cases and the public health impacts between the drug or substance abuse due to pandemic. © 2022, Hacettepe University, Faculty of Pharmacy. All rights reserved.","PeriodicalId":39138,"journal":{"name":"Hacettepe University Journal of the Faculty of Pharmacy","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86390928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Derivative Spectrophotometric Methods for the Analysis and Stability Studies of Ranolazine in Bulk and Dosage Forms 原料药和剂型雷诺嗪的导数分光光度法分析及稳定性研究
Hacettepe University Journal of the Faculty of Pharmacy Pub Date : 2022-01-29 DOI: 10.52794/hujpharm.1029049
Noon Kmai̇l, S. Shantier, E. Gadkariem
{"title":"Derivative Spectrophotometric Methods for the Analysis and Stability Studies of Ranolazine in Bulk and Dosage Forms","authors":"Noon Kmai̇l, S. Shantier, E. Gadkariem","doi":"10.52794/hujpharm.1029049","DOIUrl":"https://doi.org/10.52794/hujpharm.1029049","url":null,"abstract":"","PeriodicalId":39138,"journal":{"name":"Hacettepe University Journal of the Faculty of Pharmacy","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79289288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Meme Kanseri Tedavisindeki Güncel Yaklaşımlar
Hacettepe University Journal of the Faculty of Pharmacy Pub Date : 2022-01-27 DOI: 10.52794/hujpharm.959879
Pelin İrem Sert, Zekiye Tuba TÜYLÜ KÜÇÜKKILINÇ
{"title":"Meme Kanseri Tedavisindeki Güncel Yaklaşımlar","authors":"Pelin İrem Sert, Zekiye Tuba TÜYLÜ KÜÇÜKKILINÇ","doi":"10.52794/hujpharm.959879","DOIUrl":"https://doi.org/10.52794/hujpharm.959879","url":null,"abstract":"","PeriodicalId":39138,"journal":{"name":"Hacettepe University Journal of the Faculty of Pharmacy","volume":"108 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87592564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Characteristics and Analytical Methods of Novel PDE5 Inhibitor Avanafil: An Update 新型PDE5抑制剂阿瓦那非的特性与分析方法研究进展
Hacettepe University Journal of the Faculty of Pharmacy Pub Date : 2022-01-27 DOI: 10.52794/hujpharm.1017182
A. Shrivastava
{"title":"Characteristics and Analytical Methods of Novel PDE5 Inhibitor Avanafil: An Update","authors":"A. Shrivastava","doi":"10.52794/hujpharm.1017182","DOIUrl":"https://doi.org/10.52794/hujpharm.1017182","url":null,"abstract":"","PeriodicalId":39138,"journal":{"name":"Hacettepe University Journal of the Faculty of Pharmacy","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74580586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Determination of the Rational Drug Use Awareness of University Students 大学生合理用药意识的调查
Hacettepe University Journal of the Faculty of Pharmacy Pub Date : 2022-01-21 DOI: 10.52794/hujpharm.1024991
A. Yesildag, İ. Ağirbaş, G. Yılmaz
{"title":"Determination of the Rational Drug Use Awareness of University Students","authors":"A. Yesildag, İ. Ağirbaş, G. Yılmaz","doi":"10.52794/hujpharm.1024991","DOIUrl":"https://doi.org/10.52794/hujpharm.1024991","url":null,"abstract":"Non-rational drug use harms both health and the economy. This study aims to evaluate the rational drug use awareness of undergraduate students studying in two faculties where future health professionals are trained. The study was carried out with 449 undergraduate students studying at Karadeniz Technical University (KTU) Faculty of Health Sciences and Faculty of Pharmacy. As a data collection tool, the “Consciousness Scale Towards Rational Drug Use (CRDU) in Adults” was developed by Aktas and Selvi. The descriptive information form consist - ing of 6 questions was used. SPSS 23 program was used for data analysis. Of the 449 students participating in the study, 193 (43%) are pursuing bachelor’s degrees in Nursing, 160 (35.6%) in Pharmacy, and 96 (21.4%) in Health Man - agement. It was determined that the student’s awareness of rational drug usage was x̃=4.19 / s=0.44. It is thought that the students participating in the study had a relatively good level of awareness of the study findings that discussed in the literature. However, in the correct drug awareness dimension, it is seen that there are inadequacies in the fact that the drug recommendations from non-physician health personnel can also be taken into account. It is recommended to carry out studies in which the attitude, awareness or knowledge level of rational drug use is measured through valid and reliable scales.","PeriodicalId":39138,"journal":{"name":"Hacettepe University Journal of the Faculty of Pharmacy","volume":"54 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86511974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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