Cellular Therapy and Transplantation最新文献

{"title":"Microbiota of nasal cavity in sinusitis following hematopoietic stem cell transplantation","authors":"O. Dolgov, S. Karpishchenko, E. Utimisheva, Diana Grigoryanz, Anna Spiridonova, I. Moiseev, L. Zubarovskaya, A. Chukhlovin, A. Kulagin","doi":"10.18620/ctt-1866-8836-2022-11-1-36-42","DOIUrl":"https://doi.org/10.18620/ctt-1866-8836-2022-11-1-36-42","url":null,"abstract":"","PeriodicalId":39111,"journal":{"name":"Cellular Therapy and Transplantation","volume":"122 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88082266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pre- and post-transplantation factors associated with primary graft failure and severe poor graft function after allogeneic hematopoietic stem cell transplantation for chronic myeloid leukemia","authors":"E. Morozova, T. Rudakova, J. Vlasova, M. Barabanshchikova, Tatiana Gindina, A. Alyanskiy, M. Vladovskaya, I. Moiseev, L. Zubarovskaya, A. Kulagin","doi":"10.18620/ctt-1866-8836-2022-11-1-13-23","DOIUrl":"https://doi.org/10.18620/ctt-1866-8836-2022-11-1-13-23","url":null,"abstract":"Summary Allogeneic stem cell transplantation (allo-HSCT) is used worldwide for long-term management and cure of hematological malignancies, still remaining a valuable option for treatment of chronic myeloid leukemia (CML) in all fit patients who are unable to achieve a durable complete cytogenetic response after treatment with tyrosine kinase inhibitors (TKIs), and in advanced-phase disease. Along with relapse risk, the unfavorable HSCT results may be associated with primary graft failure (PrGF), or poor graft function (PoGF). Hence, the aim of our study was to assess frequency and outcome of PrGF and severe poor graft function (sPGF) after allo-HSCT in CML patients.","PeriodicalId":39111,"journal":{"name":"Cellular Therapy and Transplantation","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89229894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High-dose chemotherapy with autologous hemopoietic stem cell transplantation in children with retinoblastoma. Literature review and case series","authors":"K. Sergeenko, Yana Dokuchaeva, I. Kostareva, Tim Aliev, A. Elfimova, Nikolay Stepanian, Yu. V. Lozovan, N. Burlaka, N. Sidorova, E. Machneva, T. Gorbunova, T. Ushakova, V. Polyakov, K. Kirgizov, S. Varfolomeeva","doi":"10.18620/ctt-1866-8836-2022-11-1-6-12","DOIUrl":"https://doi.org/10.18620/ctt-1866-8836-2022-11-1-6-12","url":null,"abstract":"","PeriodicalId":39111,"journal":{"name":"Cellular Therapy and Transplantation","volume":"64 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85142059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcomes of liver transplantation to the patients with hepatocellular carcinoma from living donors versus transplants from deceased donors","authors":"M. Abdelfattah, H. Elsiesy","doi":"10.18620/ctt-1866-8836-2022-11-1-43-49","DOIUrl":"https://doi.org/10.18620/ctt-1866-8836-2022-11-1-43-49","url":null,"abstract":"","PeriodicalId":39111,"journal":{"name":"Cellular Therapy and Transplantation","volume":"37 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88084482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Therapeutic potential of mouse bone marrow mesenchymal stromal cells transplantation in ameliorating of CCL4-induced liver damage (in vivo study)","authors":"Dima Joujeh, Abduljalil Ghrewaty, Chadi Soukkarieh, Adnan Almarrawi, Jamal Abdul Naser Darwicha","doi":"10.18620/ctt-1866-8836-2022-11-1-58-68","DOIUrl":"https://doi.org/10.18620/ctt-1866-8836-2022-11-1-58-68","url":null,"abstract":"","PeriodicalId":39111,"journal":{"name":"Cellular Therapy and Transplantation","volume":"96 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75818271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An optimized protocol for mouse bone marrow mesenchymal stromal cells isolation and culture","authors":"Dima Joujeh, Abduljalil Ghrewaty, Chadi Soukkarieh, Adnan Almarrawi, Jamal Abdul Naser Darwicha","doi":"10.18620/ctt-1866-8836-2021-10-3-4-61-70","DOIUrl":"https://doi.org/10.18620/ctt-1866-8836-2021-10-3-4-61-70","url":null,"abstract":"Ctt JOurnal | VOLUME 10 | NUMBER 3-4 | OCTOBER-DECEMBER 2021 Dima Joujeh 1, Abduljalil Ghrewaty 1, Chadi Soukkarieh 2, Adnan Almarrawi 1, Jamal Abdul Naser Darwicha 3 1 Department of Biotechnology Engineering, Faculty of Technical Engineering, University of Aleppo, Syria 2 Department of Animal Biology, Faculty of Sciences, Damascus University, Syria 3 Department of Pharmacology and Toxicology, Faculty of Pharmacy, Arab International University, Syria. An optimized protocol for mouse bone marrow mesenchymal stromal cells isolation and culture Cellular Therapy and Transplantation (CTT). Vol. 10, No. 3-4, 2021 doi: 10.18620/ctt-1866-8836-2021-10-3-4-61-70 Submitted: 08 October 2021, accepted: 12 November 2021","PeriodicalId":39111,"journal":{"name":"Cellular Therapy and Transplantation","volume":"119 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77467977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mutual influence of malignant cells and cellular microenvironment: prospects for manipulating tumour microenvironment with nanomaterials","authors":"A. Malkova, S. Ageev, A. Abdelhalim, O. Molchanov, D. Maistrenko, K. Semenov, V. Sharoyko","doi":"10.18620/ctt-1866-8836-2021-10-3-4-8-18","DOIUrl":"https://doi.org/10.18620/ctt-1866-8836-2021-10-3-4-8-18","url":null,"abstract":"","PeriodicalId":39111,"journal":{"name":"Cellular Therapy and Transplantation","volume":"45 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83650634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Experience in the use of a radio-oriented augmented reality navigation system for biopsy of a neoplasm of the lower jaw","authors":"A. Lysenko, A. Yaremenko, V. Ivanov, S. Strelkov, Elizaveta Ivanova","doi":"10.18620/ctt-1866-8836-2021-10-3-4-78-83","DOIUrl":"https://doi.org/10.18620/ctt-1866-8836-2021-10-3-4-78-83","url":null,"abstract":"Ctt JOurnal | VOLUME 10 | NUMBER 3-4 | OCTOBER-DECEMBER 2021 Anna V. Lysenko 1, Andrey I. Yaremenko 2, Vladimir M. Ivanov 3, Sergey V. Strelkov 3, Elizaveta A. Ivanova 2 1 Department of Maxillofacial Surgery, Research Institute of Dentistry and Maxillofacial Surgery, St. Petersburg, Russia 2 Department of Maxillofacial Surgery, Pavlov University, St. Petersburg, Russia 3 Peter the Great St. Petersburg Polytechnic University, St. Petersburg, Russia Experience in the use of a radio-oriented augmented reality navigation system for biopsy of a neoplasm of the lower jaw Cellular Therapy and Transplantation (CTT). Vol. 10, No. 3-4, 2021 doi: 10.18620/ctt-1866-8836-2021-10-3-4-78-83 Submitted: 06 December 2021, accepted: 17 December 2021","PeriodicalId":39111,"journal":{"name":"Cellular Therapy and Transplantation","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75055299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Journey of a hematopoietic stem cell transplantation center through COVID-19 pandemic: one-year experience","authors":"A. Siniaev, M. Popova, Y. Rogacheva, Anna Spiridonova, M. Averyanova, A. Alyanskiy, Bella I. Ayubova, Elena Babenko, Evgenii Bakin, I. Barkhatov, M. Bogomolny, T. Bykova, A. Vitrischak, M. Vladovskaya, Y. Vlasova, A. Alisa, A. Gevorgian, Tatiana Gindina, O. Goloshchapov, K. Ekushov, M. Estrina, N. Ivanova, M. Kucher, A. Chukhlovin, K. Lepik, I. Markova, N. Mikhailova, E. Morozova, A. Osipova, O. Paina, Dmitrii E Pevtsov, A. Smirnova, A. Shvetsov, L. Stelmakh, Galina Stolbenko, L. Zubarovskaya, S. Bondarenko, I. Moiseev, A. Kulagin","doi":"10.18620/ctt-1866-8836-2021-10-3-4-30-37","DOIUrl":"https://doi.org/10.18620/ctt-1866-8836-2021-10-3-4-30-37","url":null,"abstract":"Hematopoietic stem cell transplantation (HSCT) is a life-saving procedure for oncological, hematologi-cal and non-malignant disorders. Despite global trend for a decrease of transplantation activity in view of the COVID-19 pandemic, we tried to maintain it by taking preventive measures and optimizing infection control in our center. Patients and methods This is an observational study. We collected the performance data of our transplant center from April 2020 to July 2021, i.e., during two waves of the pandemic. The main objectives were to study the influence of COVID-19 pandemic on the workflow of the HSCT center, including morbidity among employees and HSCT recipients, as well as on the transplant activity. Results The first case of COVID-19 infection in St. Petersburg was recorded on March 8, 2020. On March 30, 2020, a national lockdown had been imposed in the Russian Federation. The second wave of COVID-19 started in October 2020. Weekly screening of staff and patients was the main diagnostic tool, in addition to the governmental requirements. In sum, a total of 21702 PCR tests for SARS-CoV-2 were performed over the study period. As for July 1, 2021, 69.7% of employees became immune to the virus, due to previous COVID-19 disease, or by vaccination. In 2020, we managed to perform 419 HSCT, including 136 autologous and 283 allogeneic transplants. For comparison, 415 HSCTs were carried out in 2019, with 144 autologous and 271 allogeneic transplants. In 2020, the HSC donorship was shifted towards unrelated donors from the Russian Registry and haploidentical donors. Incidence of COVID-19 among HSCT recipients between April 2020 and July 2021 was 7.3% (n=39), being 8.6% (n=31) after allogeneic HSCT, and 4.5% (n=8) following auto-HSCT. The median age of patients with COVID-19 was 27 years (4-66). The median term for the COVID-19 onset was 68 days post-transplant (-1 to +2093). In most patients – 29 (74.3%) the HCT CI comorbidity index at the time of transplantation was 0. The stem cell source were either peripheral blood stem cells (n=22, 56.4%), or bone marrow (n=17, 43.6%). Most of the patients achieved complete remission of the underlying disease at the time of HSCT (n=30, 76.9%). The overall 100-day survival rate among HSCT recipients since the diagnosis of the COVID-19 was 79.5% (95% CI 0.609 – 0.884). The mortality rate was 20.5% (n=8). The causes of death were as follows: COVID-19 – 50% (n=4);secondary infectious complications, 25% (n=2);relapse of the underlying disease, 12.5% (n=1);hemorrhagic complications, 12.5% (n=1). The 100-day cumulative incidence of transplant-related mortality (TRM) among all HSCT recipients was 7% (95% CI 0.9 – 0.95) and 8.7% (95% CI 0.88 – 0.93) in 2019 and 2020, respectively (p=0.35). Conclusions Due to preventive measures, regular PCR screening, as well as the use of donors from the Russian Registry or haploidentical donors, we managed to maintain HSCT activity at the same level. The COVID-19 morbidity of HSCT re","PeriodicalId":39111,"journal":{"name":"Cellular Therapy and Transplantation","volume":"70 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85042476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A case of rare pediatric unclassified NK/T cell lymphoma","authors":"Andrey V. Kozlov, O. Bogdanova, A. Gevorgian, E. Volchkov, A. Botina, V. Baykov, E. Morozova, Natalya Mikhailova, L. Zubarovskaya","doi":"10.18620/ctt-1866-8836-2021-10-3-4-54-60","DOIUrl":"https://doi.org/10.18620/ctt-1866-8836-2021-10-3-4-54-60","url":null,"abstract":"","PeriodicalId":39111,"journal":{"name":"Cellular Therapy and Transplantation","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73402091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}