Northern International Medical College Journal最新文献

{"title":"Thiamine deficiency - Beriberi – A forgotten disease","authors":"Mahmuda Hassan, H. Rahman, B. Yasmeen, A. Mukti, Hakimul Haque, M. H. Khan, M. Begum, Sudipta Roy, T. Ahmed, A. U. Ahmed, S. Tabassum, A. Kabir","doi":"10.3329/nimcj.v10i1.39331","DOIUrl":"https://doi.org/10.3329/nimcj.v10i1.39331","url":null,"abstract":"Thiamine (vitamin B1) was the first B vitamin which has been identified. It serves as a cofactor for several enzymes involved in energy metabolism. The thiamine-dependent enzymes are important for the biosynthesis of neurotransmitters and for the production of reducing substances used in oxidant stress defenses, as well as for the synthesis of pentose used as nucleic acid precursors. Thiamine also plays a central role in cerebral metabolism. There are 2 major manifestations of thiamine deficiency(TD): cardiovascular disease (wet beriberi) and nervous system disease (dry beriberi and Wernicke–Korsakoff syndrome). In wet beriberi, cardiomyopathy with edema and lactic acidosis and in dry beriberi, peripheral neuropathy occurs. Manifestations of Wernicke–Korsakoff syndrome, consist of nystagmus, ophthalmoplegia and ataxia evolving into confusion, retrograde amnesia, cognitive impairment and confabulation. Thiamine deficiency is now very rare in developed countries, but still common in South East Asia specially in developing countries like Bangladesh. It is an important public health problem with potentially fatal consequences. Now a days highly polished rice (Minicut rice) is a popular staple food and other primary dietary sources of thiamine are in short supply. In wet beriberi myocardial disease is prominent which causes a high cardiac output with peripheral vasodilation and warm extremities. Before heart failure, tachycardia, a wide pulse pressure, sweating, warm skin and lactic acidosis develop leading to salt and water retention by the kidneys. The resulting fluid overload leads to edema of the dependent extremities. If it is left untreated the severity of potential outcome will be increased even up to death. Therefore, makes it essential for physician, cardiologists and Paediatrician to have an understanding of this condition and its optimal treatment. Patients on a strict thiamine-deficient diet display a state of severe depletion within 18 days. The most common cause of thiamine deficiency in affluent countries is either alcoholism or malnutrition in nonalcoholic patients especially in children. Treatment by thiamine supplementation is beneficial for diagnostic and therapeutic purposes. \u0000Northern International Medical College Journal Vol.10(1) Jul 2018: 351-354","PeriodicalId":389586,"journal":{"name":"Northern International Medical College Journal","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130801737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Liver dialysis: a bridge to liver transplantation or regeneration","authors":"B. Yasmeen","doi":"10.3329/nimcj.v10i1.39313","DOIUrl":"https://doi.org/10.3329/nimcj.v10i1.39313","url":null,"abstract":"Abstract not available \u0000Northern International Medical College Journal Vol.10(1) Jul 2018: 324-325","PeriodicalId":389586,"journal":{"name":"Northern International Medical College Journal","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134427635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pattern of Respiratory Diseases among Admitted Children in Pediatric Pulmonology Unit : A Tertiary Center Experiences","authors":"Jotsna Ara Begum, M. Mamun, Akhand Tanzih Sultana, Kamruzzaman, Afm Ashik Imran, Mst Laizuman Nahar","doi":"10.3329/NIMCJ.V9I2.38913","DOIUrl":"https://doi.org/10.3329/NIMCJ.V9I2.38913","url":null,"abstract":"Background :_The spectrum of respiratory illness is wide and includes diseases of upper and lower airways, communicable and non-communicable types. The variation in pattern of morbidity mortality of respiratory illness may be affected by different environmental and climatic variation in different parts of the world.Objective : The present study intended to explore the pattern of respiratory illnesses seen in Bangladeshi children admitted with respiratory illnesses.Methods :_The present prospective observational study was conducted in children up to 12 years of age admitted with acute respiratory illness in pulmonology unit of Dhaka Shishu (Children) Hospitalfrom July 2012 to July 2013. All children between the age limit with acute respiratory illness were included in the study. A standardized questionnaire was formulated and pretested. Then the data were collected through interview by using the questionnaire. Data were analyzed using SPSS version 17.Results : Total 1169 patients were admitted under pulmonology unit during July 2012 to June 2013 among them 324(27.7%) were admitted with respiratory diseases. Among the respiratory diseases Pneumonia (71.2%), Acute Bronchiolitis (20.1%), Bronchial Asthma (4.2%) and TB (2.7%) were commonest. Bronchopneumonia, Acute Bronchiolitis, Bronchial Asthma and TB was common among under 5 children and less common after 5 years. Male were predominate in every cases. Majority of respiratory cases were belonged to poor socioeconomic status. Pneumonia (50.7%) and Acute Bronchiolitis (58.5%) cases were found during autumn and late autumn. Asthma was common during late autumn and winter and Tuberculosis was common throughout the year. Mortality was higher among pneumonia cases.Conclusions :_Respiratory illness contributes most common cause of admission in tertiary care pediatric hospital. Bronchopneumonia is still the commonest respiratory disease with leading cause of mortality.Northern International Medical College Journal Vol.9(2) Jan 2018: 308-310","PeriodicalId":389586,"journal":{"name":"Northern International Medical College Journal","volume":"183 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121265422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Divided and Separated Sigmoid Colostomy in Anorectal Malformation : Six Years Experience at Dhaka Shishu Hospital","authors":"D. Hossain, Shahjahan, Saifullah, K. M. N. Ferdous, M. K. Islam","doi":"10.3329/NIMCJ.V9I2.38914","DOIUrl":"https://doi.org/10.3329/NIMCJ.V9I2.38914","url":null,"abstract":"Background : There are various surgical options for management of anorectal malformations (ARM). Colostomy is a common part of the management of high anorectal malformation in the pediatric population.Objective : The aim of this study was to find out the most common complications after formation of divided sigmoid colostomy.Methods : This prospective observational study was done in the Division of Pediatric Surgery, Bangladesh Institute of Child Health and Dhaka Shishu (Children) Hospital, Dhaka from January 2012 to December 2017. Divided and separated sigmoid colostomy was doneon 116 patients admitted with ARM during this period. Follow up on 2nd, 4th and 8th week after operation was done and in each follow up patients were assessed clinicallyfor wound infection, skin excoriation, prolapse of colostomy, retraction of colostomy and parastomal hernia. If colostomy complications were found then managed as per standard method.Results : The mean age of patients was 2.43±1.29 days and majority of the patients 66 (56.9%) were male.About half of the patients 50(43.1%) had fistula and 21(18.1%) patients had associated anomaly. Among 116 patients 51 (43.97%) developed complications after colostomy. The most common complication was skin excoriation found in 35 (30.2%) patients followed by wound infection in 8(6.9%). Prolapse and retraction of colostomy was found only in 6 (5.17%)and 2 (1.7%) cases respectively. No patient developed parastomal hernia and there was no mortality.Conclusion : Divided and separated sigmoid colostomy provided satisfactory outcome in the management of high anorectal malformation. Skin excoriation was the most common complication and few developed wound infection and prolapse of colostomy.Northern International Medical College Journal Vol.9(2) Jan 2018: 311-314","PeriodicalId":389586,"journal":{"name":"Northern International Medical College Journal","volume":"51 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124856321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mode of delivery and fetal outcome in meconium stained amniotic fluid in DMCH","authors":"F. Nesa, F. Chowdhury, B. Yasmeen, S. Rahman, N. Begum, Sk Akbar Hossain","doi":"10.3329/nimcj.v9i2.38912","DOIUrl":"https://doi.org/10.3329/nimcj.v9i2.38912","url":null,"abstract":"Background : Meconium is a dark greenish mass of desquamated cells, mucus, and bile that accumulates in the bowel of a fetus and is typically discharged shortly after birth. Meconium stained amniotic fluid (MSAF) has long been considered to be a bad predictor of fetal outcome.Objective : The aim of this study was to determine if the perinatal outcome is affected by mode of delivery in meconium-stained amniotic fluid.Methodology : This ovservational study was carried out in the department of Obstetrics and Gynaecology in Dhaka Medical College Hospital from July 2016 to June 2017. A total of 204 women who satisfied the inclusion and exclusion criteria were taken for the study. The study group comprised of 102 women admitted in labour and having meconium stained amniotic fluid and 102 women in labour but having clear amniotic fluid were taken as comparision group.Results : The mean age was found 26.6±5.9 years in MSAF group and 26.2±5.0 years in clear liquor group. The mean gestational age was found 38.9±1.8 weeks in MSAF group and 38.5±1.3 weeks in clear liquor group. Risk factors were not statistically significant (p>0.05) between two groups. Forty-one (40.2%) patients had caesarian section in MSAF group and 19(18.6%) in clear liquor group. APGAR score at 1 minute and at 5 minute were statistically significant (p<0.05) between two groups. About 100(98.0%) babies were alive in MSAF group and 101(99.0%) in clear liquor group.Conclusion : Meconium stained amniotic fluid group was associated with higher rate of cesarean delivery, increased need for neonatal resuscitation, increased rate of PIH, pre-eclamsia, Oligohydramnios, IUGR, Post dated pregnancy, Rh incompatibility, GDM and long time hospital stay and hospital mortality.Northern International Medical College Journal Vol.9(2) Jan 2018: 304-307","PeriodicalId":389586,"journal":{"name":"Northern International Medical College Journal","volume":"25 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120967108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Language Problem in Bangladeshi Children with Autism spectrum disorder : Observation through a Neurolinguistics Approach","authors":"F. Ferdous, B. Yasmeen, F. Alam, Mahsukur Rahman Chisty, M. Kamal, J. Ali","doi":"10.3329/NIMCJ.V9I2.38910","DOIUrl":"https://doi.org/10.3329/NIMCJ.V9I2.38910","url":null,"abstract":"Background : Autism spectrum disorder (ASD) covers a set of developmental disabilities that can cause significant social, communication, and behavioral challenges.Objective : It was aimed to find out the language problem in Bangladeshi children with Autism spectrum disorder following the neurolinguistics approach.Methodology : A descriptive observational study conducted during the period of April 2014 to December 2014 in the department of Linguistics, University of Dhaka, Bangladesh among the Bangladeshi children aged between 3–12 years. A total of 10 children with normal hearing ability who were diagnosed as ASD according to the diagnostic criteria (DSM- 5 or ICD 10) were enrolled in the study purposively from two tertiary care hospitals of Dhaka city.Results : In this study total 10 children were included and their age range was 3 to 12 years. Male was predominant (90%).Consanguinity of parents was not present in most (90%) cases,60% had positive family history of mental illness, 70% had history of delivery by lower uterine section, 80% of them were term baby. 100% children had delayed speech development, 90% was unable to indicate with index finger, 90% was unable to use noun and pronoun, 90% had repetitive words, 100% had inability to take part in rhymes, 90% was unable to play with symbols, 70% had no eye to eye contact, and 90% had no reciprocal social smile.Conclusion : Language problem in the children with ASD is an under attended problem in Bangladesh. To the authors’ best knowledge this is the first neurolinguistics approach to ASD children in Bangladesh. Further large scale extensive studies would be necessary for better visualization of the extent of the issue.Northern International Medical College Journal Vol.9(2) Jan 2018: 295-299","PeriodicalId":389586,"journal":{"name":"Northern International Medical College Journal","volume":"93 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126180014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hepatitis B Virus Subtype Distribution in Bangladeshi Chronic Carriers","authors":"Bushra Tanzem, S. Tabassum, S. Munshi, M. Jahan","doi":"10.3329/nimcj.v9i2.38908","DOIUrl":"https://doi.org/10.3329/nimcj.v9i2.38908","url":null,"abstract":"Background : Hepatitis B virus (HBV) infection is one of the major global health problems and this virus has many variants that differ from epidemiological distributions, transmission sources, clinical outcomes, diagnostic assays as well as therapeutic responses. HBV was also divided into 9 different subtypes which has distinct geographical distributions and important for the epidemiological studies and vaccine development.Objective : Bangladesh is an intermediate prevalence region for HBV infection, however, very little is known about the incidence of HBV subtypes in circulation. Therefore, we investigated the HBV subtype distribution in Bangladesh.Method : A small cohort was performed on between March 2014 and August 2017 with 172 HBV DNA positive patients from the BSMMU. From them, 29 HBV DNA samples were isolated for sequencing by Sanger method. HBsAg subtypes were determined by identifying of 226 amino acid (aa) positions in the small surface (S) gene.Result : Our study showed that HBV subtype adrq+ was in 17 (58.6%) isolates, ayw3 in 8 (27.5%), ayw2 in 2 (6.9%) and adw2 in 2 (6.9%) isolates.Conclusion : We conclude subtype adrq+ predominant in Bangladesh. This was followed by ayw3, while adw2 and ayw2 were least dominant. Subtype adw2 and adrq+ strains are found to be related with more complication, therefore, patients infected with these HBV strains need to be careful monitoring to assess their clinical outcome in future.Northern International Medical College Journal Vol.9(2) Jan 2018: 286-290","PeriodicalId":389586,"journal":{"name":"Northern International Medical College Journal","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124630572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Insulin administration Devices–an update","authors":"B. Yasmeen","doi":"10.3329/nimcj.v9i2.38907","DOIUrl":"https://doi.org/10.3329/nimcj.v9i2.38907","url":null,"abstract":"Abstract not availableNorthern International Medical College Journal Vol.9(2) Jan 2018: 283-285","PeriodicalId":389586,"journal":{"name":"Northern International Medical College Journal","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131328002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study of Primary Amenorrhea with etiology in out door patient of Rupganj Upazilla Health Complex","authors":"S. Sultana, N. Sultana, S. Ullah, Salma Akter Walida, Parul Akter, F. Ahmed","doi":"10.3329/NIMCJ.V9I2.38911","DOIUrl":"https://doi.org/10.3329/NIMCJ.V9I2.38911","url":null,"abstract":"Background : Amenorrhea means without menstruation. Primary Amenorrhea is the absence of menstruation by 16 years of age in the presence of normal secondary sexual characteristics or by 14 years of age if secondary sexual characteristics have not developed.Objectives : To explore the prevalence of Primary Amenorrhea with etiology in outdoor patient with limited investigation sourcesMethods : This was a cross sectional study conducted at Rupganj Upazila Health Complex (UHC) from January 2014 to June 2016. During this period total 2500 patients attended at Gynae out patient department (OPD). Among them 45 patients was sorted out with Primary amenorrhea. History and physical examination was done for presence or absence of secondary sexual characteristics, external genital abnormalities. Investigations were ultrasonogram (USG), Hormonal test were Follicle stimulating Hormone (FSH), Lutilizing hormones (LH), Serum Prolactin, Thyroid Stimulating Hormone. Karyotyping done. Data were analysed by using SPSS version 20.Result : In our study prevalence of Primary Amenorrhea was 1.8%. Among them infantile uterus was 17.78%, imperforated hymen was 13.33%. Turner mosaic 11.4%, mullarian agenesis 6.66%, gonadal agenesis-4.45%. hypothyroid 8.89%, hyperprolactenemia-8.89%, and 11.11% patients were with positive progesterone challenge test without anatomical and hormonal abnormalities.Conclusion : Considering the study result, Infantile uterus was the most prevalent etiological factor of amenorrhoea followed by imperforated hymen and Turner mosaic.Northern International Medical College Journal Vol.9(2) Jan 2018: 300-303","PeriodicalId":389586,"journal":{"name":"Northern International Medical College Journal","volume":"63 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122952744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiac Beriberi in an infant : An Unforgettable Dis","authors":"Mahmuda Hassan, A. Mukti, Hakimul Haque, M. H. Khan, M. Begum, Sudipta Roy, T. Ahmed, A. U. Ahmed, S. Tabassum, A. Kabir, H. Rahman","doi":"10.3329/NIMCJ.V9I2.38915","DOIUrl":"https://doi.org/10.3329/NIMCJ.V9I2.38915","url":null,"abstract":"Abstract not availableNorthern International Medical College Journal Vol.9(2) Jan 2018: 315-317","PeriodicalId":389586,"journal":{"name":"Northern International Medical College Journal","volume":"110 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115315760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}