Majalah Kesehatan Indonesia最新文献

{"title":"Ivermectin dan Covid-19: Sebuah Tinjauan Literatur","authors":"Henry Wijaya, Niluh Ayu Sri Saraswati, D. Amanda","doi":"10.47679/MAKEIN.202119","DOIUrl":"https://doi.org/10.47679/MAKEIN.202119","url":null,"abstract":"Coronavirus disease (COVID-19) is an infectious disease that has been declared a pandemic by WHO and has become a case of a health emergency in the world. This disease is caused by the novel coronavirus (SARS-CoV-2) which was first identified in China. Until now, various studies have been conducted to find the most effective drug in eradicating this pandemic. Ivermectin, an anti-parasitic drug, is known to have antiviral properties by inhibiting the entry of viruses into the cells. On this basis, Ivermectin is believed to be capable of being one of the COVID-19 therapies. This literature review is a review of emerging cases, namely COVID-19 and its relation to Ivermectin, using the published data obtained through Google Scholar, PubMed, and WHO dataIvermectin, a parasitic agent that has been approved by the FDA, was able to prevent viral proteins from entering the host cell nucleus. Ivermectin was also shown to be able to accelerate viral clearance in the body compared to the placebo group and show a significant reduction in CRP and LDH levels. Patients receiving ivermectin also showed a lower incidence of respiratory distress and a shorter duration of hospitalization. The administration of ivermectin as a COVID-19 drug can have a positive impact on patients both clinically and in the laboratory. ABSTRAK: Penyakit coronavirus (COVID-19) adalah suatu penyakit infeksi yang telah diumumkan sebagai suatu pandemi oleh WHO dan menjadi kasus gawat darurat kesehatan di dunia. Penyakit ini disebabkan oleh novel coronavirus (SARS-CoV-2) yang pertama kali di China. Hingga saat ini berbagai penelitian telah dijalankan untuk menemukan obat yang paling efektif dalam membasmi pandemi ini. Ivermectin, obat anti parasit, diketahui memiliki sifat anti virus dengan cara menghambat proses masuknya virus ke dalam sel tubuh. Dengan dasar ini, Ivermectin dipercayai mampu menjadi salah satu terapi COVID-19. Tinjauan literatur ini merupakan sebuah tinjauan kasus emerging yakni COVID-19 dan kaitannya dengan Ivermectin, dimana sumber tulisan didapatkan melalui data google cendekia, PubMed, dan WHO. Ivermectin, suatu agen parasit yang telah disetujui oleh FDA, mampu mencegah protein virus masuk ke dalam nukleus sel host. Ivermectin juga dibuktikan mampu mempercepat klirens virus di dalam tubuh dibandingkan dengan kelompok placebo dan menunjukkan penurunan yang signifikan pada kadar CRP dan LDH. Pasien-pasien yang mendapatkan ivermectin juga menunjukkan angka kejadian distres nafas yang lebih rendah dan durasi rawat inap yang lebih singkat. Pemberian ivermectin sebagai obat COVID-19 mampu memberikan dampak yang positif kepada pasien baik secara klinis maupun laboratorium.","PeriodicalId":389574,"journal":{"name":"Majalah Kesehatan Indonesia","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134019665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pengaruh Aromaterapi Lavender terhadap nyeri persalinan","authors":"Pebi Nelia Sari, Riona Sanjaya","doi":"10.47679/MAKEIN.20209","DOIUrl":"https://doi.org/10.47679/MAKEIN.20209","url":null,"abstract":"Labor pain can cause stress which causes the release of excessive hormones such as catecholamines and steroids. This hormone can cause smooth muscle tension and vasoconstriction of blood vessels. This can result in decreased uterine contractions, decreased uteroplacental circulation, reduced blood flow and oxygen to the uterus, and the emergence of uterine ischemia which increases the pain impulses. The objective of the study It was known the effect of lavender aromatherapy on labor pain in the Primary Hospital inpatient care Nur Faizha Kotabumi Selatan District North Lampung Regency in 2019. The type of research used is analytical research with the Quasi Experiment approach. The population in this study were all vaginal delivery mothers at Nur Faizha Kotabumi Primary Hospital Clinic in North Lampung Regency in January 2019. The samples in this study were 27 people. Univariate and Bivariate analysis uses the T-test. The results showed that the average level of pain in the first maternity before measuring aromatherapy was 4.89 with a standard deviation of 1.396. The average level of pain in the maternal second measurement after administration of aromatherapy is 3.52 with a standard deviation of 0.975. The results of the statistical test obtained a p-value of 0,001, so it can be concluded that there is a significant difference between aromatherapy for maternal pain. Need to do socialization especially for health workers who carry out childbirth assistance (doctors, midwives, and nurses) for the provision of aromatherapy in childbirth assistance that is proven to reduce the level of pain. Abstrak: Nyeri persalinan dapat menimbulkan stres yang menyebabkan pelepasan hormon yang berlebihan seperti katekolamin dan steroid. Hormon ini dapat menyebabkan terjadinya ketegangan otot polos dan vasokonstriksi pembuluh darah. Hal ini dapat mengakibatkan penurunan kontraksi uterus, penurunan sirkulasi uteroplasenta, pengurangan aliran darah dan oksigen ke uterus, serta timbulnya iskemia uterus yang membuat impuls nyeri bertambah banyak. Tujuan penelitian Diketahui pengaruh aromaterapi lavender terhadap nyeri persalinan di Klinik Pratama rawat inap Nur Faizha Kecamatan Kotabumi Selatan Kabupaten Lampung Utara Tahun 2019. Jenis penelitian yang digunakan adalah penelitian analitik dengan pendekatan Quasi Eksperimen. Populasi dalam penelitian ini adalah seluruh ibu bersalin pervaginam di Klinik Pratama Rawat Inap Nur Faizha Kotabumi Kabupaten Lampung Utara pada bulan Januari 2019. Sampel dalam penelitian ini berjumlah 27 orang. Analisa Univariat dan Bivariat menggunkan uji T. Hasil penelitian didapat Rata-rata tingkat nyeri pada ibu bersalin pengukuran pertama sebelum pemberian aromaterapi adalah  4,89 dengan standar deviasi 1,396. Rata-rata tingkat nyeri pada ibu bersalin pengukuran kedua sesudah pemberian aromaterapi yaitu 3,52 dengan standar deviasi 0,975. Hasil uji statistik didapatkan nilai p value 0,001, maka dapat disimpulkan ada perbedaan yang signifikan ant","PeriodicalId":389574,"journal":{"name":"Majalah Kesehatan Indonesia","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131218736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evidence-Based Practice: Efektivitas Metode Horizontal dan Roll Terhadap Penurunan Indeks Plak Gigi","authors":"Enisah Enisah, Ait Maryani, Annafis N. Toscania, D. Hendrawati, Evinila Rachmawati, Gira Lugina, Lina Melianawati, Maria U. Kulsum, Risca Arief, Suparji Suparji, Y. R. Pramanik","doi":"10.47679/MAKEIN.20206","DOIUrl":"https://doi.org/10.47679/MAKEIN.20206","url":null,"abstract":"Kasus anak dengan karies gigi anak kelas 1 sampai kelas 3 di Sekolah Dasar (SD) Muhammadiyah 2 Kelurahan Kebon Jayanti Kota Bandung yaitu 69 anak dari 87 anak (79,31 persen) dari total jumlah murid kelas tersebut. Tujuan penelitian ini yaitu systematic review mengenai efektifitas menyikat gigi metode horizontal dan roll terhadap penurunan indeks plak sebagai evidence-based practice (EBP). Metode penelitian menggunakan Critical Appraisal Skills Programme (CASP) Systematic Review yang terdiri dari 11 daftar pertanyaan. Pembuatan rumusan pertanyaan klinis menggunakan format PICOT. Hasil systematic review diperoleh sebanyak 3 bukti dari hasil penelitian. Nilai CASP Systematic Review sebesar 77 persen dan memiliki level of evidence 3, karena penelitian tersebut menggunakan desain studi quasi experiment. Metode horizontal lebih efektif dibandingkan dengan metode roll dalam menurunkan indeks plak pada gigi pada anak usia sekolah dasar. Metode horizontal dapat diaplikasikan untuk menurunkan indeks plak pada siswa kelas 1 sampai 3 di SD Muhammadiyah 2 Kelurahan Kebonjayanti Kota Bandung. Abstract: The case of children with dental caries in grade 1 to 3 at Elementary School (SD) Muhammadiyah 2, Kelurahan Kebonjayanti, Bandung City, namely 69 out of 87 children (79.31 percent) of the total number of students. The objective of this systematic review is to obtain the effectiveness of horizontal and roll brushing methods on the reduction of the teeth plaque index as evidence-based practice (EBP). The research method uses the Critical Appraisal Skills Program (CASP) Systematic Review which consists of 11 lists of questions. Formulation of clinical questions using the PICOT format. The results of the systematic review obtained as much as 3 evidence from the research results. The CASP Systematic Review score is 77 percent and has a level of evidence 3 because this research uses a quasi-experimental study design. The horizontal method is more than the roll method in reducing the plaque index on teeth in children. It can be applied to reduce the plaque index in grade 1 to 3 at SD Muhammadiyah 2, Kelurahan Kebonjayanti, Bandung City.","PeriodicalId":389574,"journal":{"name":"Majalah Kesehatan Indonesia","volume":"91 2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128014870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hasil Pemeriksaan Laboratorik pada Ibu Preeklampsia dengan Risiko Terjadinya Severe Maternal Morbidity","authors":"Iis Tri Utami, Mohammad Hakimi","doi":"10.47679/MAKEIN.20208","DOIUrl":"https://doi.org/10.47679/MAKEIN.20208","url":null,"abstract":"Morbidity and mortality in preeclampsia are still very high. In order to reduce maternal morbidity and mortality, serious efforts are needed. Those efforts are prevention, early treatment, appropriate therapeutic management and laboratory assessment. That examination can predict the risk of preeclampsia in pregnant women to severe maternal morbidity. In this study, the researcher only examined laboratory assessment results, that are platelet examination, creatine and SGOT /AST. The research hypothesis of Severe Maternal Morbidity was found more in preeclamptic mothers whose laboratory results were abnormal compared to preeclamptic mothers whose laboratory results were normal. The sample of the study was all preeclampsia mothers from January 1st, 2014 to December 31st, 2017. The abnormal laboratory examination results for preeclampsia women with the occurrence of severe maternal morbidity obtained p-value 0,001 and OR 4,384 (95 percent CI: 2,053 - 9,361). This can be concluded that mothers with abnormal laboratory results are at risk of experiencing severe maternal morbidity 4,384 times compared to mothers with normal laboratory results. The conclusions of laboratory examination results. Have a significant relationship with the occurrence of severe maternal morbidity Abstrak: Morbiditas dan mortalitas pada preeklampsia masih sangat tinggi,untuk menurunkan angka morbiditas dan mortalitas maternal diperlukan upaya sungguh-sungguh yaitu dengan melakukan usaha pencegahan, penanganan dini, manajemen terapi yang tepat dan penilaian laboratorik sehingga dapat memprediksi risiko perkembangan preeklampsia pada ibu hamil menjadi severe maternal morbidity. Dalam penelitian ini, peneliti hanya meneliti hasil penilaian laboratorik yaitu pemeriksaan trombosit, kreatin, SGOT/AST. Hipotesis penelitian Severe Maternal Morbidity lebih banyak di jumpai pada ibu Preeklampsia yang hasil laboratorik tidak normal dibandingkan dengan ibu preeklampsia yang hasil laboratorik normal. Penelitian ini merupakan penelitian kohort retrospektif. Sampel dalam penelitian ini semua ibu preeklampsia periode 01 Januari 2014 sampai dengan 31 Desember 2017. Hasil pemeriksaan laboratorik tidak normal pada ibu preeklampsia dengan terjadiny severe maternal morbidity didapatkan nilai p value 0,000 dan OR 4,384 (95 persen CI: 2,053 – 9,361). Hal tersebut dapat diartikan bahwa ibu dengan hasil laboratorik tidak normal berisiko mengalami severe maternal morbidity 4,384 kali dibandingkan hasil lab normal. Simpulan hasil pemeriksaan laboratorik mempunyai hubungan signifikan dengan terjadinya severe maternal morbidity.","PeriodicalId":389574,"journal":{"name":"Majalah Kesehatan Indonesia","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127575542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Keberhasilan Toilet Training pada Anak Usia Toddler ditinjau dari Penggunaan Disposable Diapers","authors":"Feri Kameliawati, Lea Armay, Yenny Marthalena","doi":"10.47679/MAKEIN.202012","DOIUrl":"https://doi.org/10.47679/MAKEIN.202012","url":null,"abstract":"Menurut Survey Kesehatan Rumah Tangga, diperkirakan balita yang susah mengontrol BAB dan BAK sekolah mencapai 75 juta anak. Pada survey  didapatkan anak usia toddler sebanyak 123 yang berhasil menjalankan toileting 25 persen dan 75 persen gagal. Berdasarkan hasil presurvey yang dilakukan di Posyandu Desa Wonodadi terdapat 156 anak usia toddler dan didapatkan 7 anak dari 10 anak yang masih mengompol saat malam hari, dengan pola kebiasaan di masalalu menggunakan popok sekali pakai saat beraktivitas dirumah maupun saat berpergian. Tujuan penelitian ini adalah Untuk mengetahui apakah ada hubungan penggunaan disposable diapers dengan keberhasilan Toilet training pada anak usia toddler di desa wonodadi. Desain yang digunakan penelitian adalah korelasi dengan  menggunakan metode pendekatan cross sectional. Menggunakan Tehnik Random Sampling untuk memilih 78 responden orang tua yang mempunyai anak toddler. Analisis bivariat dalam penelitian ini menggunakan Uji Chi-Square. Berdasarkan hasil uji dengan chi squarediperoleh nilai p value = 0,48  lebih dari α = 0,05 yang menunjukan bahwa tidak ada hubungan penggunaan disposable diapers dengan keberhasilan toilet training.  Hasil penelitian ini diharapkan dapat menambah pengetahuan tentang hubungan antara penggunaan disposable diapers dengan toilet training pada anak usia toddler.","PeriodicalId":389574,"journal":{"name":"Majalah Kesehatan Indonesia","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130550998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}