Open Hypertension Journal最新文献_第9页

Modulation of Reactive Oxygen Species and Collagen Synthesis by Angiotensin II in Cardiac Fibroblasts 血管紧张素II对心肌成纤维细胞中活性氧和胶原合成的调节

Open Hypertension Journal Pub Date : 2011-05-16 DOI: 10.2174/1876526201104010001

P. Lijnen, J. Prihadi, J. Pelt, R. Fagard

引用次数: 11

Pharmacogenomics of Adrenergic Receptors; from Hypertension to Heart Failure 肾上腺素能受体的药物基因组学研究从高血压到心力衰竭

Open Hypertension Journal Pub Date : 2010-09-28 DOI: 10.2174/1876526201003010014

S. Nonen, J. Azuma, Y. Fujio

引用次数: 1

The Renin Angiotensin System and the Metabolic Syndrome~!2010-02-12~!2010-04-19~!2010-06-25~! 肾素血管紧张素系统与代谢综合征2010-02-12 2010-04-19 2010-06-25

Open Hypertension Journal Pub Date : 2010-07-06 DOI: 10.2174/1876526201003010001

C. Wang, Feng Li, N. Takahashi

引用次数: 18

Possible Ameliorative Effect of Antioxidant (Taurine) in Pregnant Toxemic Female Rats 抗氧化剂(牛磺酸)对怀孕毒血症雌性大鼠可能的改善作用

Open Hypertension Journal Pub Date : 2009-10-23 DOI: 10.2174/1876526200902010001

Ibrahim M.A. El-Agousa, D. E. El-Nashar, S. Eissa, Mona N. Sharoud

{"title":"Possible Ameliorative Effect of Antioxidant (Taurine) in Pregnant Toxemic Female Rats","authors":"Ibrahim M.A. El-Agousa, D. E. El-Nashar, S. Eissa, Mona N. Sharoud","doi":"10.2174/1876526200902010001","DOIUrl":"https://doi.org/10.2174/1876526200902010001","url":null,"abstract":"The present study was designed to investigate the possible effects of the antioxidant taurine on pregnant adriamycin (ADR) induced toxemic female rats. ADR was injected intraperitoneally to 50 pregnant female rats (5 groups) to induce toxemia. the first is Frank control group injected only with saline; the second group is the Taurine group that determined the effect of taurine alone; the third group is the Toxemic group that showed the toxicity of Adriamycin; the fourth group is the Therapeutic group (Adriamycin followed by Taurine) and the fifth group is the Protective group (Taurine followed by Adriamycin) that showed the amelurative effect of taurine in these groups. Blood pressure, liver and kidney function, lipid profile, taurine concentration in plasma, serum cortisone, T3 &T4 were measured for all animals. Furthermore, histopathological examination and morphometric study for liver, kidney and cardiac muscle were done for all groups. The results showed that, the Protective group has marked improvement in most biochemical parameters than the Therapeutic group compared to Toxemic group. Morphometric study revealed a significant decrease in the nuclear area in the tissues of toxemic rats. Also, marked disturbances were observed in the histopathological architecture of the kidney, liver and heart in all toxemic rats. However, a marked improvement in morphometrical parameters and histopathological architecture was observed in protective group. The results support the ameliorative effect of taurine in the protection against toxemia during pregnancy in experimental animals.","PeriodicalId":38918,"journal":{"name":"Open Hypertension Journal","volume":"2 1","pages":"1-15"},"PeriodicalIF":0.0,"publicationDate":"2009-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68144629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Long-Term Therapy with Nifedipine-CR Improves Arterio-Sclerosis Related Markers in Patients with Untreated Essential Hypertension 硝苯地平- cr长期治疗可改善未经治疗的原发性高血压患者动脉硬化相关标志物

Open Hypertension Journal Pub Date : 2009-01-02 DOI: 10.2174/1876526200801010001

T. Kita, Mariko Tokashiki, K. Kitamura

引用次数: 2

Cardiovascular Disease in Patients with Chronic Kidney Disease 慢性肾病患者的心血管疾病

Open Hypertension Journal Pub Date : 1900-01-01 DOI: 10.15713/INS.JOHTN.0146

P. McCullough, Aaron Y. Kluger

引用次数: 18

Renovascular Hypertension 肾血管性高血压

Open Hypertension Journal Pub Date : 1900-01-01 DOI: 10.15713/ins.johtn.0171

J. Vijaykumar, B. C. Srinivas, K. Ravindranath, C. N. Manjunath

引用次数: 0

Hypertension in Children 儿童高血压

Open Hypertension Journal Pub Date : 1900-01-01 DOI: 10.15713/ins.johtn.0185

S. Garekar

{"title":"Hypertension in Children","authors":"S. Garekar","doi":"10.15713/ins.johtn.0185","DOIUrl":"https://doi.org/10.15713/ins.johtn.0185","url":null,"abstract":"Prevalence of hypertension (HT) in children is increasing. Part of the reason is the rise in the population of children with obesity and part is better screening for HT though far from ideal. Neonatal and infantile HT remains relatively poorly described in terms of epidemiology, normative data, and available antihypertensive medications. The 2017 American Academy of Pediatrics guidelines on the management of HT in children have used data from children with normal body mass index thereby lowering the cutoffs for definition of HT compared to earlier. HT is now staged as elevated, Stage 1 and Stage 2, making earlier terminologies obsolete. Elevated blood pressure (BP) is important as studies show that an elevated BP as a child increases risk of developing HT as an adult as well as metabolic syndrome. Ambulatory BP monitoring in pediatrics is increasingly being used in various situations though so far there is no normative data for children <120 cm in height. Investigations into the cause of HT may be limited when the patient is over 6 years of age and is overweight or obese or has family history of HT and the physical examination is normal. The two major causes of secondary HT in pediatrics are renal/reno-vascular and endocrine. Lifestyle modification plays a major role in therapy. It includes weight reduction/control by increasing physical activity, nutritious, and low-fat diet and reducing salt intake. The first-line medications for oral therapy are angiotensin converting enzyme inhibitors, angiotensin receptor blockers, thiazide diuretics, and calcium channel blockers. Lifelong follow-up is essential for care of the pediatric patient with HT.","PeriodicalId":38918,"journal":{"name":"Open Hypertension Journal","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82696736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0