Central Asian Journal of Medical Hypotheses and Ethics最新文献

{"title":"AUTHORSHIP FOR SALE: A THREAT TO THE INTEGRITY OF THE PUBLISHING ENTERPRISE","authors":"I. Benlidayı","doi":"10.47316/cajmhe.2023.4.2.09","DOIUrl":"https://doi.org/10.47316/cajmhe.2023.4.2.09","url":null,"abstract":"AUTHORSHIP FOR SALE: A THREAT TO THE INTEGRITY OF THE PUBLISHING ENTERPRISE","PeriodicalId":388483,"journal":{"name":"Central Asian Journal of Medical Hypotheses and Ethics","volume":"25 1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130995280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ONLINE MEDICAL EDUCATION PERSPECTIVES IN KAZAKHSTAN AND CENTRAL ASIA","authors":"Akerke Auanassova","doi":"10.47316/cajmhe.2023.4.2.06","DOIUrl":"https://doi.org/10.47316/cajmhe.2023.4.2.06","url":null,"abstract":"Introduction. Medical education should review online teaching methods so that doctors can use digital information effectively. Virtual education was well received during the pandemic, and teachers and students expressed satisfaction. However, male teachers and students adapted better than female teachers and students. Although online education has advantages, traditional offline education should only be replaced partially. Universities should focus on the development of virtual education and teacher training. \u0000Methods. We thoroughly analysed research works published on Web of Science, PubMed, and Scopus from the creation of these databases until May 2023. Our search terms included \"Distance learning\", \"Online education\", \"Medical education\", and \"Central Asia\", and we limited our search to English language articles. We also reviewed the literature lists of all the studies we found to identify potentially relevant articles. We carefully read all the studies and articles we identified, paying attention to the authors' names and publication dates to avoid data duplication. \u0000Inclusion and exclusion criteria. To conduct a thorough search, we searched for research articles published in journals that undergo peer review and are written in English. We only included studies that involved medical students and excluded articles that did not relate to distance learning, were published in non-peer-reviewed journals, or needed to be written in English. \u0000Conclusion. Higher education faces similar challenges and opportunities in the post-pandemic era, despite variations in cultural backgrounds and educational systems across countries. Improvements are also needed in online medical education, which can be achieved through the development of online training courses, individual tracking, technical control, professional support, and specialised evaluation. Such improvements will make medical training more accessible and sustainable for doctors in all areas. Innovative technologies will be necessary to ensure high-quality medical education in the future.","PeriodicalId":388483,"journal":{"name":"Central Asian Journal of Medical Hypotheses and Ethics","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117025700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ELECTRICAL PROPERTIES OF CANCER","authors":"Souichi Ishigame","doi":"10.47316/cajmhe.2023.4.2.03","DOIUrl":"https://doi.org/10.47316/cajmhe.2023.4.2.03","url":null,"abstract":"Although the relationship between cancer and electric potential has been studied for a long time, there are few published studies regarding this relationship. There is an electric potential difference between cancer and normal tissue, which disappears during chemotherapy. Furthermore, this electric potential difference increases in fast-growing cancers. Conversely, cancer may develop around abnormal electric potential differences in the body. These abnormal charges and electric potentials in the body can be removed by simply hugging a live tree growing in the ground. Alternatively, a tree growing in the ground and a conductive mat may be connected by conductors at several points, and a person may sleep on the conductive mat to dispel these charges. Humans and apes are genetically similar, and as apes live in trees, humans may be less likely to develop cancer if they are potentially balanced with trees growing on the ground.","PeriodicalId":388483,"journal":{"name":"Central Asian Journal of Medical Hypotheses and Ethics","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124140559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"THIAMINE AND HIGH DOSE INSULIN TREATMENT FOR SEPSIS","authors":"Patrick Bradley","doi":"10.47316/cajmhe.2023.4.2.02","DOIUrl":"https://doi.org/10.47316/cajmhe.2023.4.2.02","url":null,"abstract":"Sepsis is a major health problem and accounts for 20% of deaths worldwide. It is the most expensive condition treated in United States hospitals at $62 billion per year or about $46,000 per patient. Treatment consisting largely of fluid resuscitation and antibiotics has only a marginal impact. Mortality is about 27% for hospitalised patients and about 42% for patients in intensive care. There are two phases of sepsis – a hyperinflammatory phase and a subsequent hypoinflammatory phase. During the hyperinflammatory phase, the metabolic rate increases, and this is associated with an increase in body temperature and a rapid escalation of immune system functioning including increased numbers of leucocytes and their migration to infected and damaged tissues and increased supply and consumption of glucose to fuel this immune system. During the subsequent hypoinflammatory phase, the metabolic rate decreases, and this is associated with a decrease in body temperature and a generalised decrease in the physiological activity of many organs including the immune system akin to hibernation. The activated immune system has priority for the available glucose over most other organs and physiological functions during such potentially life-threatening circumstances. Thus, adenosine triphosphate (ATP) production by mitochondria (the source of energy at the cellular level for the organism as a whole) also has a lower priority for the available glucose relative to the activated immune system. If glucose availability is threatened, then the mitochondrial production of ATP is partially or substantially suppressed in favour of glycolysis because glycolysis can rapidly produce large quantities of ATP that are necessary for immune cell function in infected, anaerobic, ischaemic, or damaged tissues. However, glycolysis is only a temporary fix as it cannot produce the quantities of ATP necessary on an ongoing basis for the normal functioning of the healthy animal. Mitochondrial production of ATP must be recommenced for full recovery. It appears that the partial or substantial suppression of mitochondrial production of ATP by activation of the immune response becomes relatively fixated in some patients, leading to a substantial ATP deficit. This is the fundamental issue of sepsis. This paper reviews the metabolism of glucose and insulin during sepsis and concludes that high dose insulin with mild hyperglycaemia in conjunction with the intravenous administration of thiamine, an inhibitor of the pyruvate dehydrogenase kinase enzymes, to re-establish physiological ATP production by mitochondria, administered early in the hypometabolic (hypoinflammatory) phase of sepsis, may enhance survival relative to thiamine alone.","PeriodicalId":388483,"journal":{"name":"Central Asian Journal of Medical Hypotheses and Ethics","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133974019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"QUALITATIVE ASSESSMENT OF RENAL BLOOD PRESSURE USING NANOTECHNOLOGY INTERVENTION","authors":"Parthy Shah, R. Pallavali, Dinneswara Reddy Guda","doi":"10.47316/cajmhe.2023.4.2.04","DOIUrl":"https://doi.org/10.47316/cajmhe.2023.4.2.04","url":null,"abstract":"The renal system is one of the major organ systems present in the human body, it is responsible for maintaining electrolyte balance, secreting important hormones, and maintaining homeostasis in the body. Every individual has 2 kidneys which are located behind the peritoneum at the level of L2-L3 from the vertebral column. Broadly kidneys function to filter blood, purify it, and eliminate toxic waste. We propose a diagnostic test that evaluates the renal blood flow rate in the kidneys and assesses their functioning based on their hemodynamics in the given time frame. Here we aim to explore the application of nanoparticles to assess localized blood pressure in the kidney based on the illumination intensity/radioactivity. Connexin40(Cx40) is a transmembrane protein present in juxtaglomerular apparatus, Cx40 gold antibodies prepared can be conjugated with nanoparticles and introduced in renal circulation. Imaging technologies such as fluorescence/computed tomography can be used to detect these nanoparticles. Once injected they can be assessed and information on renal blood flow can be obtained. The intensity generated on screening can be used for the assessment of renal blood pressure. This information will be valuable for the assessment of kidney function.","PeriodicalId":388483,"journal":{"name":"Central Asian Journal of Medical Hypotheses and Ethics","volume":"10 1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129686757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"TOXOPLASMOSIS AND SCHIZOPHRENIA PUBLICATION ACTIVITY IN 1991-2023: A WEB OF SCIENCE-BASED BIBLIOMETRIC ANALYSIS","authors":"A. Şevik, Sevilay Alkan","doi":"10.47316/cajmhe.2023.4.2.05","DOIUrl":"https://doi.org/10.47316/cajmhe.2023.4.2.05","url":null,"abstract":"Schizophrenia is a complicated mental condition marked by signs of psychosis, often leading to social and occupational decline. Schizophrenia has a complex etiology that is a result of the interplay between environmental factors (such as infectious illnesses) and a person's genetic disposition. Recent epidemiological research indicates that Toxoplasma gondii may cause schizophrenia. T. gondii-related studies in schizophrenia were the focus of this bibliometric analysis study. The Web of Science’s electronic database was used to find T. gondii-related studies in schizophrenia. Co-authorship analyses of countries and keyword co-occurrence analyses were carried out using the VOSviewer software. In this bibliometric study, the research topic of T. gondii-related publications in schizophrenia during the last 33 years has been laid out, with the nations, organizations, authors, journals, main keywords, citations, and the top documents contributing to the basic knowledge structure. The significant increase in yearly publications implies that this research area has acquired importance on a global scale, with the United States having the most articles. The main organizations and researchers working on T. gondii studies on schizophrenia have been identified by this study.  The outcomes give a thorough overview of this study field's terrain.","PeriodicalId":388483,"journal":{"name":"Central Asian Journal of Medical Hypotheses and Ethics","volume":"75 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127358157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"EFFECTIVENESS OF REFORMER PILATES EXERCISES ON SYMPTOMS AND QUALITY OF LIFE IN CHILDREN WITH BLADDER AND BOWEL DYSFUNCTION","authors":"Fatma Nur Erçetin, Serkan Usgu, S. Tiryaki, Y. Yakut","doi":"10.47316/cajmhe.2023.4.2.01","DOIUrl":"https://doi.org/10.47316/cajmhe.2023.4.2.01","url":null,"abstract":"Objective. The study was conducted to investigate the effectiveness of reformer pilates exercises on symptoms and quality of life in children with bladder and bowel dysfunction (BBD). \u0000Methods. Children diagnosed as having BBD by a physician and aged between 5-18 years were included in this study. They were divided into two groups: urotherapy group (control) and reformer pilates group (study). Written consent was obtained from both the children and the parents. Children in both groups received a standardized urotherapy. The study group also had 30 minutes of reformer pilates exercise sessions for 2 days a week. BBD symptoms were assessed using the Voiding Disorder Symptom Scoring (VDSS) and Bladder and Bowel Dysfunction Questionnaire (BBDQ). Quality of life was assessed using the Pediatric Incontinence Questionnaire (PinQ). Assessments were performed before and 8 weeks after the reformer pilates exercises. \u0000Results. The study included 25 children (10 [40%] boys and 15 [60%] girls). Their median age was 9 years and their body mass index was 17.58 kg/m2. Of these 25 children, 16 were born by normal delivery, 9 of whom were delivered by cesarean section. None of the children used diapers during the day, but 10 of them continued to use diapers at night. The control (n = 16) and study (n = 9) groups were similar in terms of physical properties. The VDSS, BBDQ, and PinQ scores were significantly decreased in both groups (p < 0.05). The decrease in BBDQ and VDSS scores were more prominent in the study group than in the control group. The clinical trial registration number of this study is NCT05779709 (ClinicalTrials.gov.) \u0000Conclusion. Reformer pilates exercises can provide additional benefits in the treatment of children with BBD as they were effective in reducing BDD symptoms and enhancing quality of life.","PeriodicalId":388483,"journal":{"name":"Central Asian Journal of Medical Hypotheses and Ethics","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122573521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MY LIFE AS A RESEARCHER, ACTIVIST, AND VOLUNTEER","authors":"N. Ziadé","doi":"10.47316/cajmhe.2023.4.1.05","DOIUrl":"https://doi.org/10.47316/cajmhe.2023.4.1.05","url":null,"abstract":"MY LIFE AS A RESEARCHER, ACTIVIST, AND VOLUNTEER","PeriodicalId":388483,"journal":{"name":"Central Asian Journal of Medical Hypotheses and Ethics","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129082185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"UNFAMILIARITY WITH KEY ELEMENTS OF SCHOLARLY WRITING AND RESEARCH IMPEDES ETHICAL PUBLISHING","authors":"E. Barroga","doi":"10.47316/cajmhe.2023.4.1.03","DOIUrl":"https://doi.org/10.47316/cajmhe.2023.4.1.03","url":null,"abstract":"Scientific authors must become familiar with the key elements of scholarly writing and research to ensure ethical publishing. They should be proficient in writing the different sections of scholarly articles. Their knowledge of qualitative, quantitative, and mixed methods procedures must be sufficiently deep, including how to develop research questions and hypotheses. The authors must aim to be flawless when drafting scholarly articles to facilitate a deeper understanding of the extracted concepts. They should avoid duplicate publication, plagiarism, and salami science. When conducting research, the authors should ensure protection of human subjects and avoid bias.","PeriodicalId":388483,"journal":{"name":"Central Asian Journal of Medical Hypotheses and Ethics","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123595146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"BIBLIOMETRIC ANALYSIS OF PUBLICATIONS ON HEPATITIS D VIRUS PUBLISHED IN 1984–2022","authors":"Mehmet Çelik, M. Ceylan, Y. Arslan, N. G. Dinçer, Sevilay Alkan","doi":"10.47316/cajmhe.2023.4.1.02","DOIUrl":"https://doi.org/10.47316/cajmhe.2023.4.1.02","url":null,"abstract":"Background: Hepatitis D virus research has advanced in recent decades. In this study, we aim to quantitatively analyze the scientific data in the field of \"hepatitis D virus\" by using bibliometric analysis. \u0000Methods: Research documents published in the Web of Science database between 1984 and 2022 were included in the study. The search keywords were \"hepatitis D\" or \"hepatitis-D\" or \"HDV\" or \"hepatitis virus D.\" The full record and cited references of documents extracted were converted to a \"bibtex\" file as well. The R-Studio software's Bibliometrix package and Biblioshinny application are used to perform the bibliometric analysis. \u0000Results: A total of 1530 publications written by 6042 authors were identified. Most of the publications were articles (62.81%). The number of published articles increased gradually, especially after 2008. The articles of the authors were mostly published in the United States, Germany, and China. The affiliation where the most studies were conducted was Hannover Medical School (8.82%).  Also, the United States and Germany were found to be the main countries in the collaboration network. Mario Rizzetto was the author of the most published articles on HDV. The most frequently used words in the articles were \"infection,\" \"prevalence,\" and \"b-virus.\" \u0000Conclusion: Clinical and epidemiological studies on HDV were given more focus, while studies on treatment were less numerous. It can also be predicted that potent treatment options will increase more in the coming years, and the frequency of studies on this will increase.","PeriodicalId":388483,"journal":{"name":"Central Asian Journal of Medical Hypotheses and Ethics","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115398458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}