Tokai Journal of Experimental and Clinical Medicine最新文献

筛选
英文 中文
Sclerosing Hepatic Hemangioma Can Be Difficult to Differentiate from Liver Metastasis of Rectal Cancer: A Case Report. 硬化性肝血管瘤与直肠癌肝转移难以鉴别1例报告。
Hitomi Tamura, Taro Mashiko, Toshihito Ogasawara, Nana Mamuro, Yutaro Kamei, Takashi Ogimi, Hiroshi Miyakita, Yoshihito Masuoka, Shigenori Ei, Shinichiro Takahashi, Saya Miyahara, Masaki Mori, Kazuo Koyanagi, Seiichiro Yamamoto, Toshio Nakagohri
{"title":"Sclerosing Hepatic Hemangioma Can Be Difficult to Differentiate from Liver Metastasis of Rectal Cancer: A Case Report.","authors":"Hitomi Tamura, Taro Mashiko, Toshihito Ogasawara, Nana Mamuro, Yutaro Kamei, Takashi Ogimi, Hiroshi Miyakita, Yoshihito Masuoka, Shigenori Ei, Shinichiro Takahashi, Saya Miyahara, Masaki Mori, Kazuo Koyanagi, Seiichiro Yamamoto, Toshio Nakagohri","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Sclerosing hepatic hemangiomas are a rare form of cavernous hemangioma, reported in 0.2% of autopsy cases. Preoperative diagnosis is difficult because of the variety of imaging findings. Herein, we report a case of hepatic sclerosing hemangioma that was difficult to differentiate from a liver metastasis of rectal cancer.</p><p><strong>Case presentation: </strong>A 67-year-old man visited our hospital with a chief complaint of bleeding during defecation, and a colonoscopy revealed advanced rectal cancer. A dynamic contrast-enhanced magnetic resonance imaging (MRI) showed a 15 mm-sized tumor in S7 of the liver. In the arterial phase, the tumor interior showed low signal intensity, and the tumor margins were enhanced. The tumor interior was gradually stained from portal to equilibrium phases. Partial S7 resection was performed for liver metastasis from rectal cancer. Hematoxylin and Eosin staining revealed flattened endothelial cells with poor atypia that formed a lumen. Immunohistochemical staining was positive for CD31 and CD34, and the final diagnosis was sclerosing hemangioma.</p><p><strong>Conclusion: </strong>Although a rare tumor, hepatic sclerosing hemangioma should always be considered as a differential diagnosis for liver tumors. If the diagnosis is difficult to make and malignancy cannot be ruled out, resection may be indicated as a diagnostic treatment.</p>","PeriodicalId":38819,"journal":{"name":"Tokai Journal of Experimental and Clinical Medicine","volume":"50 1","pages":"37-42"},"PeriodicalIF":0.0,"publicationDate":"2025-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143658819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Low Pretreatment CALLY Index Predicts Early Recurrence in Resected UICC Stage I Pancreatic Ductal Adenocarcinoma. 低预处理CALLY指数预测切除的UICC期胰管腺癌早期复发。
Taro Mashiko, Toshihito Ogasawara, Yoshihito Masuoka, Shigenori Ei, Shinichiro Takahashi, Masaki Mori, Kazuo Koyanagi, Seiichiro Yamamoto, Toshio Nakagohri
{"title":"Low Pretreatment CALLY Index Predicts Early Recurrence in Resected UICC Stage I Pancreatic Ductal Adenocarcinoma.","authors":"Taro Mashiko, Toshihito Ogasawara, Yoshihito Masuoka, Shigenori Ei, Shinichiro Takahashi, Masaki Mori, Kazuo Koyanagi, Seiichiro Yamamoto, Toshio Nakagohri","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>We aimed to identify the inflammation-based prognostic score (IBPS) that can be used to predict the recurrence of early-stage pancreatic ductal carcinoma (PDAC).</p><p><strong>Methods: </strong>In this retrospective study, the data of 109 patients with Union for International Cancer Control (UICC) stage I PDAC who underwent pancreatectomy between January 2005 and December 2020 at Tokai University Hospital were assessed. The clinicopathological and risk factors for early recurrence were compared between the early (within 12 postoperative months) recurrence (ER) group (n = 29) and non-ER group (n = 80).</p><p><strong>Results: </strong>The median overall survival (OS) durations of the ER and non-ER groups were 15.0 (95% confidence interval [CI]: 8.0-22.0) and 109.0 (95% CI: 91.4-120.9) months, respectively (p < 0.001). The patients in the ER group had a significantly poorer prognosis. Multivariate analysis showed that the C-reactive protein-albumin-lymphocyte (CALLY) index ( < 4.4) (hazard ratio [HR]: 2.71, 95% CI: 1.21-6.02]), positive venous invasion (HR: 4.67, 95% CI: 1.10-19.90), tumor differentiation (moderately/poorly) (HR: 2.25, 95% CI: 2.05-13.43), and failure to complete adjuvant chemotherapy (HR: 12.50, 95% CI: 5.30-29.50) were independent risk factors for early recurrence.</p><p><strong>Conclusions: </strong>Low pretreatment CALLY index was a useful predictor of early recurrence in patients with UICC stage I PDAC.</p>","PeriodicalId":38819,"journal":{"name":"Tokai Journal of Experimental and Clinical Medicine","volume":"50 1","pages":"25-33"},"PeriodicalIF":0.0,"publicationDate":"2025-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143658818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sigmoid Colon Perforation After Upper Gastrointestinal Series in Two Japanese Men: A Case Report. 2例日本男性上消化道术后乙状结肠穿孔1例报告。
Seiji Nakahara, Junichi Kaneko, Rika Fujino, Hisamichi Yoshii, Hideki Izumi, Kazuhito Nabeshima, Tomoko Sugiyama, Takuma Tajiri, Masaya Mukai, Hiroyasu Makuuchi
{"title":"Sigmoid Colon Perforation After Upper Gastrointestinal Series in Two Japanese Men: A Case Report.","authors":"Seiji Nakahara, Junichi Kaneko, Rika Fujino, Hisamichi Yoshii, Hideki Izumi, Kazuhito Nabeshima, Tomoko Sugiyama, Takuma Tajiri, Masaya Mukai, Hiroyasu Makuuchi","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Colorectal perforation following an upper gastrointestinal series is rare. The majority of patients are women. Only 4 cases of perforation have been reported in men with the English literature. Here, we report two more cases of sigmoid colon perforation after an upper gastrointestinal series in men.</p>","PeriodicalId":38819,"journal":{"name":"Tokai Journal of Experimental and Clinical Medicine","volume":"50 1","pages":"10-13"},"PeriodicalIF":0.0,"publicationDate":"2025-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143658822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Infective Endocarditis Caused by Methicillin-Resistant Staphylococcus epidermidis in the Infant of a Mother with Diabetes: A Case Report. 糖尿病母亲所生婴儿耐甲氧西林表皮葡萄球菌所致感染性心内膜炎1例。
Kaori Inukai, Tomofumi Otomo, Yoshifumi Murayama, Junko Nakajima, Hiroki Kawamura, Kosuke Tabe, Yumi Sato, Shinichi Matsuda, Yoshiyuki Yamada, Hitoshi Ishimoto, Atsushi Uchiyama
{"title":"Infective Endocarditis Caused by Methicillin-Resistant <i>Staphylococcus epidermidis</i> in the Infant of a Mother with Diabetes: A Case Report.","authors":"Kaori Inukai, Tomofumi Otomo, Yoshifumi Murayama, Junko Nakajima, Hiroki Kawamura, Kosuke Tabe, Yumi Sato, Shinichi Matsuda, Yoshiyuki Yamada, Hitoshi Ishimoto, Atsushi Uchiyama","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Infective endocarditis (IE) is a rare but severe condition caused by microbial infection of the endocardium. It affects both adults and children with underlying conditions or immunosuppression, including infants of mothers with diabetes (IDMs). We report a case of IE caused by methicillin-resistant <i>Staphylococcus epidermidis</i> (MRSE) in a newborn IDM. A male infant was born at 38 weeks gestation, weighing 5,102 g. His mother had poorly-controlled type 2 diabetes, and the infant had asymmetric septal hypertrophy of the heart. He was admitted to our unit with severe hypoglycemia and respiratory distress necessitating treatment using an indwelling peripherally-inserted central catheter (PICC). The tip of the PICC was moved to the appropriate position because it was initially located in the patient's right ventricle. He was determined to have IE via a positive MRSE blood culture and vegetation in the right atrium. He was treated with vancomycin followed by surgery at 74 days of age to remove the vegetation. He recovered well and was discharged at 92 days of age. IDMs whose mothers have poorly-controlled diabetes may be at higher risk of IE, particularly if they have hemodynamic abnormalities and indwelling PICCs. However, further studies are warranted to confirm this hypothesis.</p>","PeriodicalId":38819,"journal":{"name":"Tokai Journal of Experimental and Clinical Medicine","volume":"50 1","pages":"21-24"},"PeriodicalIF":0.0,"publicationDate":"2025-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143658269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Case of Seborrheic Keratosis in an Adolescent: Quite Rare Disease in Japan. 1例青少年脂溢性角化病:在日本相当罕见的疾病。
Tomomichi Shimizu, Fumikazu Yamazaki, Hanako Yamaoka, Akio Kondoh, Masayuki Kato, Tomotaka Mabuchi
{"title":"A Case of Seborrheic Keratosis in an Adolescent: Quite Rare Disease in Japan.","authors":"Tomomichi Shimizu, Fumikazu Yamazaki, Hanako Yamaoka, Akio Kondoh, Masayuki Kato, Tomotaka Mabuchi","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A 19-year-old woman with three seborrheic keratosis on her right abdomen and five seborrheic keratosis on her both buttocks is presented. That developed at the age of five and two months prior to the visit. At our initial dermatological examination, we noticed three oval, well defined, brown tumors on her right abdomen, and several round, well defined, brown nodules on her both buttocks. Dermoscopy findings showed comedo-like openings, fissures, and ridges. Histopathological examination showed hyperkeratosis and pseudohorn cysts, and basaloid keratinocytes proliferation with no dysplastic cells. These findings were consistent with SK. She was treated by cryotherapy using a liquid nitrogen spray, and her tumors and nodules dropped off entirely. Juvenile-onset of seborrheic keratosis is quite rare in East Asian countries and needs to be differentiated from keratinocytic epidermal nevus.</p>","PeriodicalId":38819,"journal":{"name":"Tokai Journal of Experimental and Clinical Medicine","volume":"50 1","pages":"34-36"},"PeriodicalIF":0.0,"publicationDate":"2025-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143658023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Influence of Combination Therapy with Dulaglutide or Liraglutide and SGLT2 Inhibitors on Renal Outcomes in Patients with Type 2 Diabetes: A Post-hoc Analysis of the RECAP Study. 杜拉鲁肽或利拉鲁肽与SGLT2抑制剂联合治疗对2型糖尿病患者肾脏预后的影响:RECAP研究的事后分析
Yoshimi Muta, Kazuo Kobayashi, Masao Toyoda, Shunichiro Tsukamoto, Daisuke Tsuriya, Yuichi Takashi, Hisashi Yokomizo, Kei Takeshita, Takuya Hashimoto, Moritsugu Kimura, Kouichi Tamura, Keizo Kanasaki, Daiji Kawanami
{"title":"Influence of Combination Therapy with Dulaglutide or Liraglutide and SGLT2 Inhibitors on Renal Outcomes in Patients with Type 2 Diabetes: A Post-hoc Analysis of the RECAP Study.","authors":"Yoshimi Muta, Kazuo Kobayashi, Masao Toyoda, Shunichiro Tsukamoto, Daisuke Tsuriya, Yuichi Takashi, Hisashi Yokomizo, Kei Takeshita, Takuya Hashimoto, Moritsugu Kimura, Kouichi Tamura, Keizo Kanasaki, Daiji Kawanami","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>We report that the effect of combination therapy with SGLT2 inhibitors (SGLT2i) and glucagon-like peptide-1 receptor agonists (GLP1Ra) on renal composite outcomes is not affected by the preceding drug in patients with type 2 diabetes (T2D). In this study, we performed a post-hoc analysis of dulaglutide and liraglutide users and investigated the differences between GLP1Ra.</p><p><strong>Methods: </strong>We analyzed 266 patients treated with an SGLT2i followed by dulaglutide or liraglutide and 194 treated with dulaglutide or liraglutide followed by an SGLT2i. In addition, we analyzed dulaglutide users (n = 246) and liraglutide users (n = 214). Renal composite outcome was defined as the progression of albuminuria and/or a ≥ 30% eGFR decline.</p><p><strong>Results: </strong>The incidence of renal composite outcomes in the SGLT2i-preceding and GLP1Ra (dulaglutide or liraglutide)-preceding groups was not significantly different. It also did not differ between the dulaglutide and liraglutide users. The incidence of ≥ 30% eGFR decline was more frequent in liraglutide users, with an odds ratio of 2.63 (95% confidence interval: 1.07-6.45, p = 0.04), with a significantly larger decrease in albuminuria in liraglutide users, with an odds ratio of 0.44 (95% confidence interval: 0.04-0.85, p = 0.03).</p><p><strong>Conclusions: </strong>Dulaglutide and liraglutide may have different effects on albuminuria and the kidney function in combination with SGLT2i.</p>","PeriodicalId":38819,"journal":{"name":"Tokai Journal of Experimental and Clinical Medicine","volume":"50 1","pages":"1-9"},"PeriodicalIF":0.0,"publicationDate":"2025-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143658343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Carcinoid Tumor of the Middle Ear: A Report of Two Cases. 中耳类癌2例报告。
Hikaru Yamamoto, Akihiro Sakai, Takanobu Teramura, Kyoko Odagiri, Go Ogura, Kazuhito Hatanaka, Takuma Tajiri, Naoya Nakamura, Masashi Hamada
{"title":"Carcinoid Tumor of the Middle Ear: A Report of Two Cases.","authors":"Hikaru Yamamoto, Akihiro Sakai, Takanobu Teramura, Kyoko Odagiri, Go Ogura, Kazuhito Hatanaka, Takuma Tajiri, Naoya Nakamura, Masashi Hamada","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Carcinoid tumors of the middle ear are rare and difficult to diagnose preoperatively. These low-grade malignant tumors require complete surgical removal; however, consensus on the amount of radicality required is lacking. Herein, we report two cases of carcinoid tumors of the middle ear.</p><p><strong>Case presentation: </strong>The first patient was a 40-year-old woman who presented with right-sided hearing loss and a white mass behind the tympanic membrane. The tumor was surgically removed using a transcanal approach, while maintaining an intact ossicular chain. The histopathological diagnosis was carcinoid tumor, and no additional treatment was administered. The second patient was a 28-year-old woman who presented with left-sided hearing loss and a white mass in the ear canal. Preoperative biopsy revealed a carcinoid tumor. The tumor was excised using the same approach as in Case 1 with tentative removal of the incus during surgery, and reconstruction with tympanoplasty type IIIc (Ost) was performed. No recurrence was observed in either case during > 3 years of follow-up.</p><p><strong>Conclusion: </strong>Treatment algorithms for carcinoid tumor of the middle ear are lacking; therefore, surgical plans vary according to the tumor extension. Furthermore, because carcinoid tumors are low-grade malignant tumors, long-term follow-up after complete macroscopic removal is necessary.</p>","PeriodicalId":38819,"journal":{"name":"Tokai Journal of Experimental and Clinical Medicine","volume":"50 1","pages":"14-20"},"PeriodicalIF":0.0,"publicationDate":"2025-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143658158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Laparoscopic Gastrectomy Using External Oblique Intercostal Block Versus Wound Infiltration: A Trial Protocol. 使用肋间外斜肌阻滞与伤口浸润的腹腔镜胃切除术:试验方案。
Takanori Suzuka, Nobuhiro Tanaka, Takayuki Yamanaka, Mitsuru Ida, Shota Suzuki, Kiyoshi Asada, Naoki Ozu, Masahiko Kawaguchi
{"title":"Laparoscopic Gastrectomy Using External Oblique Intercostal Block Versus Wound Infiltration: A Trial Protocol.","authors":"Takanori Suzuka, Nobuhiro Tanaka, Takayuki Yamanaka, Mitsuru Ida, Shota Suzuki, Kiyoshi Asada, Naoki Ozu, Masahiko Kawaguchi","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>A novel external oblique intercostal block (EOIB) might have analgesic effects on T6-10 and be indicated for laparoscopic gastrectomy. However, EOIB effects on postoperative pain are unknown. We aim to generate evidence to support such EOIB application. We will compare the efficacy of EOIB and wound infiltration (WI) in a single-center, single-blind, randomized controlled trial.</p><p><strong>Methods: </strong>We will assess plasma concentrations of levobupivacaine after EOIB, its pharmacokinetics, and the pinprick test in patients randomly assigned to receive EOIB or WI before laparoscopic or robot-assisted gastric distal or total gastrectomy. The EOIB and WI will start after general anesthesia induction with 20 and 40 mL of 0.25% levobupivacaine per side, respectively, before skin closure. The outcomes will be numeric rating scale (NRS) scores at 12 h postoperatively (primary) and postoperative NRS scores at 2, 24, and 48 h; fentanyl application; QoR-15 scores on postoperative days 1, 2, and 7; and World Health Organization Disability Assessment Schedule 2.0 scores at 3 months (secondary).</p><p><strong>Conclusions: </strong>We hope that our study will provide evidence to support EOIB application in laparoscopic surgery. Plasma concentrations will help determine levobupivacaine pharmacokinetics, which if similar to conventional nerve blocks, will indicate EOIB's safety.</p>","PeriodicalId":38819,"journal":{"name":"Tokai Journal of Experimental and Clinical Medicine","volume":"49 2","pages":"57-62"},"PeriodicalIF":0.0,"publicationDate":"2024-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141433061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ataxia Telangiectasia in a Patient with Breast Cancer: A Case Report. 乳腺癌患者共济失调性毛细血管扩张1例报告。
Mari Mizuno, Yuko Ohnuki, Ai Unzaki, Mizuho Suzuki, Kei Takeshita, Saori Takahashi, Hikaru Kiyohara, Saeko Nakagawa, Rie Ishida, Kozue Yokoyama, Mayako Terao, Takuho Okamura, Toru Hanamura, Naoki Niikura
{"title":"Ataxia Telangiectasia in a Patient with Breast Cancer: A Case Report.","authors":"Mari Mizuno,&nbsp;Yuko Ohnuki,&nbsp;Ai Unzaki,&nbsp;Mizuho Suzuki,&nbsp;Kei Takeshita,&nbsp;Saori Takahashi,&nbsp;Hikaru Kiyohara,&nbsp;Saeko Nakagawa,&nbsp;Rie Ishida,&nbsp;Kozue Yokoyama,&nbsp;Mayako Terao,&nbsp;Takuho Okamura,&nbsp;Toru Hanamura,&nbsp;Naoki Niikura","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Ataxia telangiectasia (AT) is a rare autosomal recessive disorder caused by the pathological variants of the <i>ATM</i> gene. Owing to i ts r arity a nd n ature, complications of AT, such a s malignant tumors, a re often difficult to manage with standard imaging studies and treatments, and there are no established management strategies. We report the case of a woman who had AT in childhood and developed breast cancer in her 20s; the disease was successfully managed by the decision-making of multidisciplinary physicians professionals with ethics support. She was immunocompromised, ataxic, and mentally impaired. The patient's mother noticed a tumor in her right breast and subsequently brought her to our department. Although preoperative testing and surgical procedures were limited as AT is extremely radiosensitive, the patient was diagnosed with cT2N0M0 breast cancer and underwent right mastectomy and axillary lymph node sampling. The final diagnosis was pT2N0M0 pStage IIA mucinous carcinoma, and immunohistochemistry of the tumor specimen was estrogen receptor-positive, progesterone receptor-positive, and HER2-negative. Tamoxifen was administered as postoperative adjuvant therapy, and the patient has survived to date without recurrence. Here, we report our experience with breast cancer treatment for AT, along with a review of the literature.</p>","PeriodicalId":38819,"journal":{"name":"Tokai Journal of Experimental and Clinical Medicine","volume":"48 3","pages":"95-98"},"PeriodicalIF":0.0,"publicationDate":"2023-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10105368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Possible Relationship between the Deteriorated Accuracy of Intermittent-Scanning Continuous Glucose Monitoring Device and the Contact Dermatitis: Post-hoc analysis of the ISCHIA Study. 间歇性扫描连续血糖监测设备准确度下降与接触性皮炎的可能关系:ISCHIA研究的事后分析。
Masao Toyoda, Takashi Murata, Yushi Hirota, Kiminori Hosoda, Ken Kato, Kunichi Kouyama, Ryuji Kouyama, Akio Kuroda, Yuka Matoba, Munehide Matsuhisa, Shu Meguro, Junnosuke Miura, Kunihiro Nishimura, Akira Shimada, Shota Suzuki, Atsuhito Tone, Naoki Sakane
{"title":"Possible Relationship between the Deteriorated Accuracy of Intermittent-Scanning Continuous Glucose Monitoring Device and the Contact Dermatitis: Post-hoc analysis of the ISCHIA Study.","authors":"Masao Toyoda,&nbsp;Takashi Murata,&nbsp;Yushi Hirota,&nbsp;Kiminori Hosoda,&nbsp;Ken Kato,&nbsp;Kunichi Kouyama,&nbsp;Ryuji Kouyama,&nbsp;Akio Kuroda,&nbsp;Yuka Matoba,&nbsp;Munehide Matsuhisa,&nbsp;Shu Meguro,&nbsp;Junnosuke Miura,&nbsp;Kunihiro Nishimura,&nbsp;Akira Shimada,&nbsp;Shota Suzuki,&nbsp;Atsuhito Tone,&nbsp;Naoki Sakane","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>We previously reported the mean average relative difference (MARD) of the sensor glucose (SG) of the first-generation FreeStyle Libre with the original algorithm, an intermittent scanning continuous glucose monitoring (isCGM) device, was 15.6% in the Effect of Intermittent-Scanning Continuous Glucose Monitoring to Glycemic Control Including Hypoglycemia and Quality of Life of Patients with Type 1 Diabetes Mellitus Study (ISCHIA Study). In the present study, we aimed to further analyze its accuracy in detail by conducting a post-hoc analysis of the study.</p><p><strong>Methods: </strong>The ISCHIA Study was a multicenter, randomized, cross-over trial to assess the efficacy of isCGM. The SG levels of isCGM and the measured capillary blood glucose (BG) levels of 91 participants were used for the analysis.</p><p><strong>Results: </strong>Bland-Altman analysis showed bias of -13.0 mg/dl when the SG levels were compared to the BG levels, however no proportional bias was observed (<i>r</i> = 0.085). MARD of the participants without and with contact dermatitis were 15.0 ± 6.0% and 27.4 ± 21.4% (<i>P</i> = 0.001), respectively.</p><p><strong>Conclusion: </strong>There was negative bias in the SG levels of isCGM compared to the BG levels. There is a possibility that the complication of the contact dermatitis during isCGM use may be related with deteriorated accuracy of the SG levels.</p>","PeriodicalId":38819,"journal":{"name":"Tokai Journal of Experimental and Clinical Medicine","volume":"48 3","pages":"83-90"},"PeriodicalIF":0.0,"publicationDate":"2023-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10105365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信