Tokai Journal of Experimental and Clinical Medicine最新文献

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Laparoscopic Gastrectomy Using External Oblique Intercostal Block Versus Wound Infiltration: A Trial Protocol. 使用肋间外斜肌阻滞与伤口浸润的腹腔镜胃切除术:试验方案。
Takanori Suzuka, Nobuhiro Tanaka, Takayuki Yamanaka, Mitsuru Ida, Shota Suzuki, Kiyoshi Asada, Naoki Ozu, Masahiko Kawaguchi
{"title":"Laparoscopic Gastrectomy Using External Oblique Intercostal Block Versus Wound Infiltration: A Trial Protocol.","authors":"Takanori Suzuka, Nobuhiro Tanaka, Takayuki Yamanaka, Mitsuru Ida, Shota Suzuki, Kiyoshi Asada, Naoki Ozu, Masahiko Kawaguchi","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>A novel external oblique intercostal block (EOIB) might have analgesic effects on T6-10 and be indicated for laparoscopic gastrectomy. However, EOIB effects on postoperative pain are unknown. We aim to generate evidence to support such EOIB application. We will compare the efficacy of EOIB and wound infiltration (WI) in a single-center, single-blind, randomized controlled trial.</p><p><strong>Methods: </strong>We will assess plasma concentrations of levobupivacaine after EOIB, its pharmacokinetics, and the pinprick test in patients randomly assigned to receive EOIB or WI before laparoscopic or robot-assisted gastric distal or total gastrectomy. The EOIB and WI will start after general anesthesia induction with 20 and 40 mL of 0.25% levobupivacaine per side, respectively, before skin closure. The outcomes will be numeric rating scale (NRS) scores at 12 h postoperatively (primary) and postoperative NRS scores at 2, 24, and 48 h; fentanyl application; QoR-15 scores on postoperative days 1, 2, and 7; and World Health Organization Disability Assessment Schedule 2.0 scores at 3 months (secondary).</p><p><strong>Conclusions: </strong>We hope that our study will provide evidence to support EOIB application in laparoscopic surgery. Plasma concentrations will help determine levobupivacaine pharmacokinetics, which if similar to conventional nerve blocks, will indicate EOIB's safety.</p>","PeriodicalId":38819,"journal":{"name":"Tokai Journal of Experimental and Clinical Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141433061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ataxia Telangiectasia in a Patient with Breast Cancer: A Case Report. 乳腺癌患者共济失调性毛细血管扩张1例报告。
Mari Mizuno, Yuko Ohnuki, Ai Unzaki, Mizuho Suzuki, Kei Takeshita, Saori Takahashi, Hikaru Kiyohara, Saeko Nakagawa, Rie Ishida, Kozue Yokoyama, Mayako Terao, Takuho Okamura, Toru Hanamura, Naoki Niikura
{"title":"Ataxia Telangiectasia in a Patient with Breast Cancer: A Case Report.","authors":"Mari Mizuno,&nbsp;Yuko Ohnuki,&nbsp;Ai Unzaki,&nbsp;Mizuho Suzuki,&nbsp;Kei Takeshita,&nbsp;Saori Takahashi,&nbsp;Hikaru Kiyohara,&nbsp;Saeko Nakagawa,&nbsp;Rie Ishida,&nbsp;Kozue Yokoyama,&nbsp;Mayako Terao,&nbsp;Takuho Okamura,&nbsp;Toru Hanamura,&nbsp;Naoki Niikura","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Ataxia telangiectasia (AT) is a rare autosomal recessive disorder caused by the pathological variants of the <i>ATM</i> gene. Owing to i ts r arity a nd n ature, complications of AT, such a s malignant tumors, a re often difficult to manage with standard imaging studies and treatments, and there are no established management strategies. We report the case of a woman who had AT in childhood and developed breast cancer in her 20s; the disease was successfully managed by the decision-making of multidisciplinary physicians professionals with ethics support. She was immunocompromised, ataxic, and mentally impaired. The patient's mother noticed a tumor in her right breast and subsequently brought her to our department. Although preoperative testing and surgical procedures were limited as AT is extremely radiosensitive, the patient was diagnosed with cT2N0M0 breast cancer and underwent right mastectomy and axillary lymph node sampling. The final diagnosis was pT2N0M0 pStage IIA mucinous carcinoma, and immunohistochemistry of the tumor specimen was estrogen receptor-positive, progesterone receptor-positive, and HER2-negative. Tamoxifen was administered as postoperative adjuvant therapy, and the patient has survived to date without recurrence. Here, we report our experience with breast cancer treatment for AT, along with a review of the literature.</p>","PeriodicalId":38819,"journal":{"name":"Tokai Journal of Experimental and Clinical Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10105368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Possible Relationship between the Deteriorated Accuracy of Intermittent-Scanning Continuous Glucose Monitoring Device and the Contact Dermatitis: Post-hoc analysis of the ISCHIA Study. 间歇性扫描连续血糖监测设备准确度下降与接触性皮炎的可能关系:ISCHIA研究的事后分析。
Masao Toyoda, Takashi Murata, Yushi Hirota, Kiminori Hosoda, Ken Kato, Kunichi Kouyama, Ryuji Kouyama, Akio Kuroda, Yuka Matoba, Munehide Matsuhisa, Shu Meguro, Junnosuke Miura, Kunihiro Nishimura, Akira Shimada, Shota Suzuki, Atsuhito Tone, Naoki Sakane
{"title":"Possible Relationship between the Deteriorated Accuracy of Intermittent-Scanning Continuous Glucose Monitoring Device and the Contact Dermatitis: Post-hoc analysis of the ISCHIA Study.","authors":"Masao Toyoda,&nbsp;Takashi Murata,&nbsp;Yushi Hirota,&nbsp;Kiminori Hosoda,&nbsp;Ken Kato,&nbsp;Kunichi Kouyama,&nbsp;Ryuji Kouyama,&nbsp;Akio Kuroda,&nbsp;Yuka Matoba,&nbsp;Munehide Matsuhisa,&nbsp;Shu Meguro,&nbsp;Junnosuke Miura,&nbsp;Kunihiro Nishimura,&nbsp;Akira Shimada,&nbsp;Shota Suzuki,&nbsp;Atsuhito Tone,&nbsp;Naoki Sakane","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>We previously reported the mean average relative difference (MARD) of the sensor glucose (SG) of the first-generation FreeStyle Libre with the original algorithm, an intermittent scanning continuous glucose monitoring (isCGM) device, was 15.6% in the Effect of Intermittent-Scanning Continuous Glucose Monitoring to Glycemic Control Including Hypoglycemia and Quality of Life of Patients with Type 1 Diabetes Mellitus Study (ISCHIA Study). In the present study, we aimed to further analyze its accuracy in detail by conducting a post-hoc analysis of the study.</p><p><strong>Methods: </strong>The ISCHIA Study was a multicenter, randomized, cross-over trial to assess the efficacy of isCGM. The SG levels of isCGM and the measured capillary blood glucose (BG) levels of 91 participants were used for the analysis.</p><p><strong>Results: </strong>Bland-Altman analysis showed bias of -13.0 mg/dl when the SG levels were compared to the BG levels, however no proportional bias was observed (<i>r</i> = 0.085). MARD of the participants without and with contact dermatitis were 15.0 ± 6.0% and 27.4 ± 21.4% (<i>P</i> = 0.001), respectively.</p><p><strong>Conclusion: </strong>There was negative bias in the SG levels of isCGM compared to the BG levels. There is a possibility that the complication of the contact dermatitis during isCGM use may be related with deteriorated accuracy of the SG levels.</p>","PeriodicalId":38819,"journal":{"name":"Tokai Journal of Experimental and Clinical Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10105365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Skull Base Fracture or Abuse Suspicion Based on Intraorbital Lymphangioma Secondary to Periorbital Hematoma. 基于眼眶内淋巴管瘤继发于眼眶周围血肿的颅底骨折或滥用怀疑。
Tomofumi Otomo, Kota Hirai, Takashi Sakama, Ayumi Tada, Chinami Kaiga, Kenta Kuruma, Hiromitsu Takakura, Hiroyuki Mochizuki, Masahiko Kato
{"title":"Skull Base Fracture or Abuse Suspicion Based on Intraorbital Lymphangioma Secondary to Periorbital Hematoma.","authors":"Tomofumi Otomo,&nbsp;Kota Hirai,&nbsp;Takashi Sakama,&nbsp;Ayumi Tada,&nbsp;Chinami Kaiga,&nbsp;Kenta Kuruma,&nbsp;Hiromitsu Takakura,&nbsp;Hiroyuki Mochizuki,&nbsp;Masahiko Kato","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Intraorbital lymphangiomas are among the orbital tumors that can cause sudden eye protrusion in children. In children with periorbital hematoma (panda eye sign), a skull fracture or abuse is likely first considered as the differential diagnosis. A 7-month-old boy presented to the ophthalmologist with complaints of swelling of the right upper eyelid, subconjunctival hemorrhage on the right ear side, and periorbital subcutaneous hemorrhage, which had appeared since the morning of the day before the visit. The eyeball did not protrude. Based on the interview and clinical findings, right eyeball contusion was suspected. The patient was then followed up for observation. Later, during the physical examination, the abovementioned symptoms were noted. Hence, the patient was admitted for a close examination based on the suspicion of skull base fracture and abuse. Contrast-enhanced magnetic resonance imaging (MRI) after admission revealed a multifocal cystic structure within the right intraorbital muscular cone. Thus, he was diagnosed with right intraorbital lymphangioma. Intraorbital lymphangioma may not show ocular protrusion, and this disease should be considered in cases where abuse is suspected, considering the periorbital subcutaneous hemorrhage.</p>","PeriodicalId":38819,"journal":{"name":"Tokai Journal of Experimental and Clinical Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10105366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nodular Pulmonary Amyloidosis Preceding Gastric Mucosa-associated Lymphoid Tissue Lymphoma, Initially Suspected to Be Lung Cancer. 结节性肺淀粉样变先于胃黏膜相关淋巴组织淋巴瘤,最初怀疑为肺癌。
Naokata Kutsuzawa, Hiroto Takiguchi, Haruka Ikoma, Nobue Kumaki, Tomoo Nagai, Mitsuharu Ueda, Yoshitaka Ono, Yukihiro Horio, Kyoko Niimi, Naoki Hayama, Yoko Ito, Tsuyoshi Oguma, Koichiro Asano
{"title":"Nodular Pulmonary Amyloidosis Preceding Gastric Mucosa-associated Lymphoid Tissue Lymphoma, Initially Suspected to Be Lung Cancer.","authors":"Naokata Kutsuzawa,&nbsp;Hiroto Takiguchi,&nbsp;Haruka Ikoma,&nbsp;Nobue Kumaki,&nbsp;Tomoo Nagai,&nbsp;Mitsuharu Ueda,&nbsp;Yoshitaka Ono,&nbsp;Yukihiro Horio,&nbsp;Kyoko Niimi,&nbsp;Naoki Hayama,&nbsp;Yoko Ito,&nbsp;Tsuyoshi Oguma,&nbsp;Koichiro Asano","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Nodular pulmonary amyloidosis, a subtype of pulmonary amyloidosis, is a unique disease that can mimic lung cancer on radiographic imaging and is related to lymphoproliferative disorders. In this report, we describe a case of a 76-year-old male who presented with a solitary nodule in his left lower lung lobe on computed tomography that increased from 6 mm to 13 mm in diameter over 40 months. Lung cancer was suspected; however, transbronchial lung biopsy revealed deposition of an eosinophilic and homogeneous amorphous substance, which showed apple-green birefringence under polarized light after Congo red staining, and immunohistochemistry analysis returned positive results for immunoglobulin lambda light-chain. Upper gastrointestinal endoscopy revealed a gastric mucosa-associated lymphoid tissue (MALT) lymphoma. These findings indicated that this was a case of nodular pulmonary amyloidosis that preceded a diagnosis of MALT lymphoma.</p>","PeriodicalId":38819,"journal":{"name":"Tokai Journal of Experimental and Clinical Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10105370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Simultaneous Visualization of the Thoracic Duct and Blood Vessels Using MRI: A Comparison Between Balanced Turbo-field-echo and Spin-echo. 利用MRI同时显示胸导管和血管:平衡涡场回波和自旋回波的比较。
Xuyang Sun, Tetsu Niwa, Takakiyo Nomura, Susumu Takano, Kento Yokoyama, Kotaro Iwata, Sadanori Kameda, Hiroki Kobayashi, Takuya Hara, Jun Hashimoto
{"title":"Simultaneous Visualization of the Thoracic Duct and Blood Vessels Using MRI: A Comparison Between Balanced Turbo-field-echo and Spin-echo.","authors":"Xuyang Sun,&nbsp;Tetsu Niwa,&nbsp;Takakiyo Nomura,&nbsp;Susumu Takano,&nbsp;Kento Yokoyama,&nbsp;Kotaro Iwata,&nbsp;Sadanori Kameda,&nbsp;Hiroki Kobayashi,&nbsp;Takuya Hara,&nbsp;Jun Hashimoto","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>Magnetic resonance thoracic ductography (MRTD), concomitant with blood vessel imaging, provides useful anatomical information. The purpose of this study was to assess the visibility of the thoracic duct and blood vessels simultaneously by MRTD using balanced turbo-field-echo (bTFE) and turbo spin-echo (TSE).</p><p><strong>Methods: </strong>MRTDs concomitant with blood vessel imaging on bTFE and TSE were obtained for 10 healthy volunteers with a 1.5T-magnetic resonance unit. Visibility of the thoracic duct, blood vessels in the thoracic region; motion artifacts; and overall image quality were scored by two radiologists using three-to-five-point scales; those were compared between bTFE and TSE.</p><p><strong>Results: </strong>The thoracic duct was generally well-visualized on MRTD sequences. The upper part of the thoracic duct was better visualized on TSE than on bTFE (<i>p</i> < 0.05). The blood vessels were well visualized on bTFE and TSE; the bilateral subclavian arteries and the right subclavian veins were better visualized on TSE than on bTFE (all <i>p</i> < 0.05). Motion artifacts and overall image quality were better on TSE than on bTFE (<i>p</i> = 0.0039 and 0.0020, respectively).</p><p><strong>Conclusion: </strong>MRTD concomitant with blood vessel imaging on TSE has better visibility of the thoracic duct and blood vessels than bTFE.</p>","PeriodicalId":38819,"journal":{"name":"Tokai Journal of Experimental and Clinical Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10110583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Provision of cardiosurgical care during martial law and analysis of the need for bed-places and bed-days 戒严令期间提供心脏外科护理,并分析床位和住院日的需求
Tokai Journal of Experimental and Clinical Medicine Pub Date : 2023-08-28 DOI: 10.35339/ekm.2023.92.3.rud
M. Rudenko
{"title":"Provision of cardiosurgical care during martial law and analysis of the need for bed-places and bed-days","authors":"M. Rudenko","doi":"10.35339/ekm.2023.92.3.rud","DOIUrl":"https://doi.org/10.35339/ekm.2023.92.3.rud","url":null,"abstract":"The article analyzes the duration of inpatient treatment of servicemen who needed cardiosurgical treatment during martial law. Diseases of the circulatory system, mine-explosive injuries of the chest with direct involvement of the heart and main vessels are life-threatening conditions. Statistics of combat losses during military conflicts show that 1/3 of servicemen with gunshot wounds or chest trauma die due to bleeding and cardiac arrest. With the resolution of the war in the russian federation, the need to provide highly qualified cardiosurgical care will increase. Therefore, a clear understanding of the planning of bed spaces with the calculation of bed days is necessary to ensure the provision of cardiac surgical care. The purpose of the study is to determine the need for the number of bed-places and bed-days during the stay of a sick/ wounded serviceman in a cardiosurgical hospital. The need for bed-days and the number of bed-places was studied, and a conclusion was made about the need to increase them. The amount of inpatient care provided, as well as the duration of treatment of servicemen during a local military conflict (anti-terrorist operation/joint forces operation) in the conditions of stay in a cardiac surgical hospital and compared with the amount of medical care and the duration of treatment of servicemen during martial law were analyzed. As a result of the study, a conclusion was made about the need to organize separate structural divisions for the provision of highly specialized medical care, which includes cardiovascular surgery. It was established that the need for the number of beds during a full-scale war exceeds the planned by 266.3%, and the number of bed days during the stay of a sick/wounded serviceman in a cardiac surgical hospital during martial law increased by 6.3%. Ensuring an adequate need for the number of inpatient places and a justified duration of treatment allows timely provision of quality treatment of the sick and/or wounded, providing them with timely rehabilitation and returning the serviceman to the ranks of the armed forces of Ukraine.\u0000\u0000Keywords: inpatient care, diseases of the circulatory system, cardiovascular surgery, organizational measures, provision of adequate needs, hospitalization of patients and victims.","PeriodicalId":38819,"journal":{"name":"Tokai Journal of Experimental and Clinical Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90045995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Successful Emergency Decompressive Laminectomy for Burkitt Lymphoma with Metastatic Spinal Lesions: A Case Report. 成功的紧急减压椎板切除术治疗Burkitt淋巴瘤伴脊柱转移性病变1例报告。
Hidetoshi Yano, Takashi Koike, Mayuko Shibata, Yumiko Sugishita, Naoko Kawabata, Sachio Fujita, Kosuke Akiyama, Daisuke Toyama, Yoshiyuki Yamada, Atsushi Uchiyama, Shohei Yamamoto
{"title":"Successful Emergency Decompressive Laminectomy for Burkitt Lymphoma with Metastatic Spinal Lesions: A Case Report.","authors":"Hidetoshi Yano,&nbsp;Takashi Koike,&nbsp;Mayuko Shibata,&nbsp;Yumiko Sugishita,&nbsp;Naoko Kawabata,&nbsp;Sachio Fujita,&nbsp;Kosuke Akiyama,&nbsp;Daisuke Toyama,&nbsp;Yoshiyuki Yamada,&nbsp;Atsushi Uchiyama,&nbsp;Shohei Yamamoto","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Although Burkitt lymphoma (BL) usually arises in the abdomen or pelvis, it can also arise in the epidural space as a primary or secondary site and present with back pain or limb weakness. Emergency management is necessary to relieve spinal cord compression (SCC). Herein, we report a case of BL with metastatic spinal lesions in a 16-year-old female who presented with sudden-onset progressive walking difficulty. She was admitted to a previous hospital where she presented with abdominal pain and vomiting and was diagnosed with intussusception via a computed tomography scan. Laparoscopic small bowel resection was performed, during which a diagnosis of BL was made on the basis of pathological examination. Sudden numbness in the extremities and the complete inability to walk occurred ten days after surgery. Thoracolumbar MRI revealed a metastatic mass extending from C7 to T6 with evidence of SCC. Emergency decompressive laminectomies (from C7 to T6) and partial debulking of the tumor were performed 12 hours after the onset of her neurologic symptoms. She was subsequently treated with chemotherapy, and she made a complete neurologic recovery. Emergency decompressive laminectomies for BL with spinal lesions could effectively lead to the recovery of neurologic symptoms.</p>","PeriodicalId":38819,"journal":{"name":"Tokai Journal of Experimental and Clinical Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9688864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Numerical Simulation of Nasal Resistance Using Three-dimensional Models of the Nasal Cavity and Paranasal Sinus. 基于鼻腔和副鼻窦三维模型的鼻阻力数值模拟。
Shoji Kaneda, Fumiyuki Goto, Kenji Okami, Reo Mitsutani, Yoko Takakura
{"title":"Numerical Simulation of Nasal Resistance Using Three-dimensional Models of the Nasal Cavity and Paranasal Sinus.","authors":"Shoji Kaneda,&nbsp;Fumiyuki Goto,&nbsp;Kenji Okami,&nbsp;Reo Mitsutani,&nbsp;Yoko Takakura","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>Previously, we used a nasal cavity model to analyze the intranasal airflow dynamics and numerically calculate the nasal resistance value. In this study, We attempted clarify the parameters influencing nasal resistance by newly developed computer model.</p><p><strong>Methods: </strong>The computer simulation model was developed from the structures of nasal airway tract adopted from 1.0-mm slice computed tomography (CT) obtained from the 2 of the healthy volunteers. (model 1: the one at 35-year-old man, model 2: 25-year-old man.) We have calculated the nasal resistance by computer simulation calculations of both model 1 and model 2. These calculated values were compared with the values obtained from the established method of rhinomanometry. For the simulation, Fluent 17.2® (ANSYS, American) was employed for f luid a nalysis u sing the continuity equation for 3D incompressible flow and the Navies-Stokes equation for the basic equations. Both models were laminar models. The SIMPLE calculation method using the finite volume method was employed here, and the quadratic precision upwind difference method was used to discretize the convection terms.</p><p><strong>Results: </strong>The measured (simulation) values in Model 1 were 0.69 (0.48), 1.10 (0.41), and 0.42 (0.22) Pa/cm<sup>3</sup>/s on the right, left, and both sides, whereas those in Model 2 were 0.72 (0.21), 0.32 (0.09), and 0.22 (0.06) Pa/cm<sup>3</sup>/s, respectively.</p><p><strong>Conclusion: </strong>Our results suggest that nasal resistance is possibly affected by the length of the inferior turbinate and the cross-sectional area of the choana and nasopharynx. Further experiments using additional nasal cavity and paranasal sinus models are warranted.</p>","PeriodicalId":38819,"journal":{"name":"Tokai Journal of Experimental and Clinical Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9691833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The First Application of Intraumbilical Longitudinal Incision to Pyloromyotomy for Hypertrophic Pyloric Stenosis. 创伤内纵切口在幽门肌切开术治疗肥厚性幽门狭窄中的首次应用。
Keisuke Suzuki, Makoto Komura, Ryosuke Satake, Kan Terawaki, Tetsuro Kodaka, Takumi Gohara, Hironobu Yonekawa
{"title":"The First Application of Intraumbilical Longitudinal Incision to Pyloromyotomy for Hypertrophic Pyloric Stenosis.","authors":"Keisuke Suzuki,&nbsp;Makoto Komura,&nbsp;Ryosuke Satake,&nbsp;Kan Terawaki,&nbsp;Tetsuro Kodaka,&nbsp;Takumi Gohara,&nbsp;Hironobu Yonekawa","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>There are several approaches to pyloromyotomy for the treatment of hypertrophic pyloric stenosis including open transumbilical pyloromyotomy and laparoscopic pyloromyotomy. Beginning in 2012, we adopted intraumbilical longitudinal incision as a new transumbilical approach for pyloromyotomy. We describe details of the operative technique and results of this new approach.</p><p><strong>Methods: </strong>We reviewed records of patients undergoing transumbilical pyloromyotomy from 2005 to 2018. Perioperative outcomes were compared between intraumbilical longitudinal incision and supraumbilical incision, the latter of which is the conventional incision for transumbilical pyloromyotomy.</p><p><strong>Results: </strong>Twenty-four patients underwent pyloromyotomy with intraumbilical longitudinal incision (intraumbilical group) and 28 patients with supraumbilical incision (supraumbilical group). The median operative time was longer in the intraumbilical group (58.0 vs. 43.5 min, p = 0.002). However, the time to full feeding did not differ significantly between the two groups, and the median postoperative stay was shorter in the intraumbilical group (3 vs. 5.5 days, p = 0.003). There was no difference in the rate of complications (4.2% vs. 7.1%, p = 1.0). Scars after intraumbilical longitudinal incision were localized inside the umbilicus.</p><p><strong>Conclusion: </strong>Pyloromyotomy can be performed through intraumbilical longitudinal incision as safely as supraumbilical incision and intraumbilical longitudinal incision may improve cosmetic results. This approach can be an alternative technique for pyloromyotomy.</p>","PeriodicalId":38819,"journal":{"name":"Tokai Journal of Experimental and Clinical Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9691831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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