P and T最新文献_第8页

American Heart Association 2018 Scientific Sessions. 美国心脏协会2018年科学会议。

P and T Pub Date : 2019-01-01

Walter Alexander

引用次数: 0

Drug and Device News. 药品和器械新闻。

P and T Pub Date : 2019-01-01

引用次数: 0

Research Briefs. 研究简报。

P and T Pub Date : 2019-01-01

引用次数: 0

Intravenous Acetaminophen For the Management of Pain During Vaso-occlusive Crises in Pediatric Patients. 静脉注射对乙酰氨基酚治疗小儿血管闭塞危象期疼痛。

P and T Pub Date : 2019-01-01

Paula Baichoo, Arsenia Asuncion, Gladys El-Chaar

{"title":"Intravenous Acetaminophen For the Management of Pain During Vaso-occlusive Crises in Pediatric Patients.","authors":"Paula Baichoo, Arsenia Asuncion, Gladys El-Chaar","doi":"","DOIUrl":"","url":null,"abstract":"Background: Children with sickle cell disease experience vaso-occlusive crises (VOC) that requires opioid pharmacotherapy. Multimodal analgesic therapy may reduce pain and opioid-induced adverse effects.Objective: The primary objective was to examine the effectiveness of intravenous (IV) acetaminophen in children presenting with pain from VOC. Secondary objectives were to document the safety and opioid-sparing effects of IV acetaminophen during VOC in pediatric patients.Setting: Children's Medical Center, NYU-Winthrop Hospital.Method: This retrospective study had two groups of patients, those who received opioids alone (group O) and those who received acetaminophen with opioids (group OA). Children two to 19 years of age who were admitted to the children's medical center for VOC were eligible for inclusion.Main outcome measure: A reduction in pain by at least 1 out of 10. With every analgesic dose, we documented pain scales and pain scores before and after each dose, the number of doses administered per day, and mg/kg/day. Data were analyzed using the mixed effect model. All opioids administered to patients were converted to morphine equivalents. We documented length of stay and adverse events.Results: We had a total of 46 children: 28 in group O and 18 in group OA. Acetaminophen reduced the pain from VOC by 2.3/10. There were trends in different assessments of opioid-sparing effects, in reducing opioid dosage (-0.5 mg/kg morphine equivalent; P = 0.45), reducing overall morphine equivalent doses (-18.5 mg; P = 0.066), and opioid-related adverse effects.Conclusion: This is the first study to demonstrate the effectiveness of IV acetaminophen in treating VOC pain in children, supporting multimodal analgesic therapy in this setting. Opioid-sparing effects were also encouraging.","PeriodicalId":38773,"journal":{"name":"P and T","volume":"44 1","pages":"5-8"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336200/pdf/ptj4401005.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36890858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neonatal Respiratory Distress Syndrome: Tackling A Worldwide Problem. 新生儿呼吸窘迫综合征:解决一个世界性的问题。

P and T Pub Date : 2019-01-01

Janet Dyer

引用次数: 0

Drug and Device News. 药品和器械新闻。

P and T Pub Date : 2018-12-01

引用次数: 0

A Bitter Pill to Swallow: Why Medication Safety Is Critical in Hepatitis C Treatment. 难以下咽的苦果:为什么药物安全对丙型肝炎治疗至关重要。

P and T Pub Date : 2018-12-01

Karyn M Sullivan, Linda M Spooner, Emily Harris, Kenneth Lowe, George M Abraham

{"title":"A Bitter Pill to Swallow: Why Medication Safety Is Critical in Hepatitis C Treatment.","authors":"Karyn M Sullivan, Linda M Spooner, Emily Harris, Kenneth Lowe, George M Abraham","doi":"","DOIUrl":"","url":null,"abstract":"Purpose: To provide medication safety tips to optimize the management of patients receiving treatment for chronic hepatitis C virus (HCV) infection.Summary: Ensuring safe medication use in patients who receive treatment for HCV infection is a crucial component in providing optimal patient care. Because of the complexity of available treatment options, numerous challenges exist in preventing medication errors with HCV therapies. This article will focus on the selection of appropriate treatment options along with proper dosing and duration, awareness of concomitant disease states and drug interactions, identifying adverse drug reactions (ADRs) and patient counseling points, the provision of adherence counseling and prevention of treatment interruptions, improving communication with patients and between pharmacies, and recognizing the importance of a multidisciplinary approach.Conclusion: Maintaining awareness of medication safety strategies geared toward HCV pharmacotherapy is critical for providing optimal care for patients while minimizing the opportunity for errors.","PeriodicalId":38773,"journal":{"name":"P and T","volume":"43 12","pages":"764-768"},"PeriodicalIF":0.0,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281151/pdf/ptj4312764.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36780986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Research Briefs. 研究简报。

P and T Pub Date : 2018-12-01

引用次数: 0

P&T Committees Get New Leeway to Control Part C and Part D Drug Costs: Door Opens to More Step Therapy And Indication-Based Formularies. P&T委员会获得控制C部分和D部分药物成本的新余地:为更多的步骤治疗和基于适应症的处方打开了大门。

P and T Pub Date : 2018-12-01

Stephen Barlas

引用次数: 0

Use of Regulations, Laws, Standards, and Best Practices When Prosecuting and Defending Hospitals in Drug Injury Lawsuits. 在药品伤害诉讼中起诉和辩护医院时使用法规、法律、标准和最佳实践。

P and T Pub Date : 2018-12-01

James T O'Donnell, F Randy Vogenberg

引用次数: 0