Polish Annals of Medicine最新文献

Molecular aspects of hereditary complement component C5 deficiency in humans 人类遗传性补体成分 C5 缺乏症的分子问题

Polish Annals of Medicine Pub Date : 2024-07-15 DOI: 10.29089/paom/188059

Hanna Szymańska

{"title":"Molecular aspects of hereditary complement component C5 deficiency in humans","authors":"Hanna Szymańska","doi":"10.29089/paom/188059","DOIUrl":"https://doi.org/10.29089/paom/188059","url":null,"abstract":"The complement system plays a key role in the host defense against pathogens. The deficiency of complement components predisposes the system to recurrent infections and autoimmune diseases. In particular, serum C5 deficiency (C5D) may be serious for human health, because this protein plays a key role in controlling infections, mainly with Neisseria spp.The aim of this article is to present the structure and function of the human C5 gene encoding complement component C5, with particular regard to the molecular characteristics of the mutations causing hereditary complement C5 deficiency.This article is based on the available literature. A total of 35 articles were included in the study.Based on the literature review, it was shown that C5 mediates inflammatory processes and bacterial cytolysis. The cause of hereditary C5 deficiency in humans is inefficient or reduced serum C5 biosynthesis, due to mutations in the C5 gene. This quantitative and functional C5 deficiency is associated with recurrent Neisseria spp. infections, the lack of bactericidal activity and an impaired ability of serum to induce chemotaxis. The molecular characterization of previously described C5D-related mutations in the human C5 gene has been performed, and the clinical presentation of some molecularly examined C5D probands has also been discussed.The deficiency of C5 protein, which bridges innate and adaptive immunity, is related with 18 different mutations in the C5 gene found in over 30 families of various origins. Screening for complement defects seems particularly important, especially in asymptomatic relatives of probands.","PeriodicalId":38569,"journal":{"name":"Polish Annals of Medicine","volume":"20 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141648337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The two faces of Blastocystis spp.: is it the cause of colorectal cancer (CRC) or a consequence of it? Blastocystis spp.的两面性：它是大肠癌（CRC）的原因还是结果？

Polish Annals of Medicine Pub Date : 2024-07-15 DOI: 10.29089/paom/188591

M. Lepczyńska

{"title":"The two faces of Blastocystis spp.: is it the cause of colorectal cancer (CRC) or a consequence of it?","authors":"M. Lepczyńska","doi":"10.29089/paom/188591","DOIUrl":"https://doi.org/10.29089/paom/188591","url":null,"abstract":"Over the last few years, there has been an increase in the prevalence of Blastocystis spp. in colorectal cancer (CRC) patients. Moreover, various in vitro and in vivo studies have highlighted that intestinal colonisation of Blastocystis spp. has an influence on host immune responses leading to cellular apoptosis and membrane permeability. It has been suggested that Blastocystis spp. is an important risk factor for the worsening of CRC.To present evidence concerning the association between CRC and Blastocystis spp.A review of the literature was performed by searching Science Direct, PubMed, Scopus and Google Scholar databases up to December, 2023.Out of all in vitro and in vivo studies selected for this review, the majority of them have confirmed a significantly higher prevalence of Blastocystis spp. in colorectal cancer patients in comparison to the control groups. Several in vitro human colorectal carcinoma cell line studies have shown significant cytopathic and immunological effects of Blastocystis spp. Additionally, in vivo experimental animal model studies have shown that Blastocystis spp. infection significantly contributed to large intestinal polyp (colorectal adenoma) formation and the progression of colorectal carcinogenesis.These studies strongly support suggestions that Blastocystis spp. could be an important factor to existing CRC development by influencing the host immune response and increasing oxidative damage.","PeriodicalId":38569,"journal":{"name":"Polish Annals of Medicine","volume":"29 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141646671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cercarial dermatitis: Clinical course and prevention 蛔虫性皮炎：临床过程和预防

Polish Annals of Medicine Pub Date : 2024-07-02 DOI: 10.29089/paom/187008

J. Korycińska

{"title":"Cercarial dermatitis: Clinical course and prevention","authors":"J. Korycińska","doi":"10.29089/paom/187008","DOIUrl":"https://doi.org/10.29089/paom/187008","url":null,"abstract":"Cercarial dermatitis (swimmer's itch) is a water-borne parasitic skin disease caused by larvae (cercariae) of a nonhuman species of schistosome. The prevailing symptoms are nodulopapular skin lesions accompanied by pruritus. The condition occurs virtually worldwide and is considered to be an emerging public health problem in Europe. In most cases, the symptoms are associated with cercariae of avian schistosomes of the genus Trichobilharzia spp.The aim of this review article is to present the most important information on the course of the disease, its diagnostics, treatment and epidemiology. Additionally, it offers an account of preventive measures targeted at reducing the risk of infection.A literature search was conducted using electronic databases such as PubMed, Google Scholar and Willey Online Library. Altogether, 40 articles were subject to analysis.The data obtained from the literature survey process were systematised and presented in 5 sections. Clinically, effective control of swimmer’s itch should comprise measures from the fields of diagnostics, treatment, epidemiology and prevention.Swimmer’s itch poses diagnostic difficulties, primarily due to the low specificity of its symptoms. Owing to a lack of conclusive data on the fate of cercariae penetrating human skin and a growing number of documented cases of cercarial dermatitis worldwide, further intensive research into the matter is warranted.","PeriodicalId":38569,"journal":{"name":"Polish Annals of Medicine","volume":"17 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141687132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of morphological parameters, PLR and NLR inflammation indicators in patients with long-term COVID-19 of mild and severe complexity 评估轻度和重度长期 COVID-19 患者的形态参数、PLR 和 NLR 炎症指标

Polish Annals of Medicine Pub Date : 2024-04-24 DOI: 10.29089/paom/185881

Samuel Stróż, P. Kosiorek, Edyta Zbroch, Bożena Mikołuć, Anna Stasiak-Barmuta

{"title":"Evaluation of morphological parameters, PLR and NLR inflammation indicators in patients with long-term COVID-19 of mild and severe complexity","authors":"Samuel Stróż, P. Kosiorek, Edyta Zbroch, Bożena Mikołuć, Anna Stasiak-Barmuta","doi":"10.29089/paom/185881","DOIUrl":"https://doi.org/10.29089/paom/185881","url":null,"abstract":"COVID-19 can have long-lasting effects, but the effects on blood parameters and inflammation are poorly understood. The aim of this study was to evaluate morphological and inflammatory markers in long-term COVID-19 patients.To evaluate complete blood count, neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and morphology in mild versus severe long COVID-19.In total, 39 long COVID-19 patients were stratified into mild (n = 25) and severe (n = 14) groups. Blood counts, NLR, PLR were measured. Cell morphology was analysed. ROC curves were used to determine biomarker thresholds. Survival was assessed using Kaplan–Meier curves.Severe patients had lower leukocytes but higher neutrophils, indicating greater inflammation. NLR and PLR were significantly increased in severe patients compared to mild patients (NLR 12 vs 8; PLR 140 vs 100). NLR and PLR were higher than in controls, confirming their utility as inflammatory markers. NLR and PLR effectively discriminated between mild and severe disease. High NLR and PLR predicted poorer prognosis. Altered leukocyte morphology such as cytoplasmic vacuolization correlated with severity.NLR and PLR are promising biomarkers for assessing severity of long COVID-19, while morphological changes in blood cells provide additional evidence of inflammation. Further studies in larger populations are warranted.","PeriodicalId":38569,"journal":{"name":"Polish Annals of Medicine","volume":"34 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140660573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synchronous early rectal adenocarcinoma and neuroendocrine tumour: A treatment strategy 同步早期直肠腺癌和神经内分泌肿瘤：治疗策略

Polish Annals of Medicine Pub Date : 2024-04-22 DOI: 10.29089/paom/185641

Dinesh Alagoo, Harivinthan Sellappan, Saravana Kumar Rajanthran, N. Azizan, Nur Farehah Johari, Andee Dzulkarnaen Zakaria, F. Hayati

{"title":"Synchronous early rectal adenocarcinoma and neuroendocrine tumour: A treatment strategy","authors":"Dinesh Alagoo, Harivinthan Sellappan, Saravana Kumar Rajanthran, N. Azizan, Nur Farehah Johari, Andee Dzulkarnaen Zakaria, F. Hayati","doi":"10.29089/paom/185641","DOIUrl":"https://doi.org/10.29089/paom/185641","url":null,"abstract":"Synchronous colorectal adenocarcinoma with neuroendocrine tumour (NET) are a unique combination of tumours. These may be incidental lesions, usually a histopathological diagnosis rather than a clinical diagnosis from symptoms, examination or even gross appearances.This paper aims to highlight our management strategy on manging a middle-aged woman with synchronous rectal adenocarcinoma and NET.A 53-year-old woman presented with lower gastrointestinal bleeding with constitutional symptoms. Clinical examination and colonoscopy revealed a classical rectal adenocarcinoma, confirmed via biopsy. However, the final histopathology reports of the resected tumour revealed an early rectal adenocarcinoma with synchronous NET.We review the relevant literature and a discussion regarding guidelines available for diagnosis, follow-up and surveillance of this rare case.There are no current guidelines for surveillance colonoscopy after detecting gastrointestinal NET, particularly synchronous tumours. NET may be another colorectal cancer risk factor with similar mutations and common genetic markers. Clinicians should consider doing a colonoscopy when or if their patients are diagnosed with any gastrointestinal NET. Detection of any NET warrants a thorough evaluation of the whole colon for colorectal cancer and close surveillance so that timely management can be achieved.","PeriodicalId":38569,"journal":{"name":"Polish Annals of Medicine","volume":"80 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140677168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Steroid response encephalopathy associated with autoimmune thyroiditis 与自身免疫性甲状腺炎相关的类固醇反应脑病

Polish Annals of Medicine Pub Date : 2024-04-16 DOI: 10.29089/paom/185642

Rushit Jashari, F. Jashari, N. Dakaj, Gentian Lila, E. Komoni, D. Boshnjaku

{"title":"Steroid response encephalopathy associated with autoimmune thyroiditis","authors":"Rushit Jashari, F. Jashari, N. Dakaj, Gentian Lila, E. Komoni, D. Boshnjaku","doi":"10.29089/paom/185642","DOIUrl":"https://doi.org/10.29089/paom/185642","url":null,"abstract":"Steroid-responsive encephalopathy associated with autoimmune thyroiditis (SREAT) is a rare autoimmune disorder affecting the central nervous system, characterized by a spectrum of neurological and psychiatric symptoms.This case study aims to highlight the diagnostic challenges and the successful management of SREAT syndrome in a young woman with autoimmune thyroiditis.A 21-year-old woman with documented Hashimoto's thyroiditis and polycystic ovary syndrome was admitted to the Clinic of Neurology following a 5-minute tonic seizure and subsequent confusion state lasting several hours. Initial brain MRI showed no abnormalities, and EEG revealed generalized slowness. Comprehensive laboratory assessments, including a complete blood count, biochemical analysis, and electrolyte panels, all yielded normal results. Further investigation revealed a significantly elevated anti-thyroid peroxidase antibody (anti-TPO) titer exceeding 1000 IU/mL. The suspicion of SREAT syndrome was considered. Pulse therapy with methylprednisolone was associated with rapid recovery. The patient was discharged from the hospital with an oral corticosteroid tapering regimen.The administration of pulse therapy with methylprednisolone resulted in a rapid and very good response in the patient, evidenced by the resolution of seizure activity and improvement in confusion. Laboratory investigations, particularly the markedly elevated anti-TPO titer, supported the diagnosis of SREAT syndrome. The subsequent management with an oral corticosteroid tapering regimen maintained the patient's clinical stability.This case highlights the importance of considering autoimmune encephalopathy in patients with a history of autoimmune thyroiditis presenting with neurological and psychiatric symptoms. Further research is warranted to better understand the underlying pathomechanisms.","PeriodicalId":38569,"journal":{"name":"Polish Annals of Medicine","volume":"18 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140696556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A focused surgical case report: Managing scoliosis in Wolf–Hirschhorn syndrome 重点手术病例报告：沃尔夫-赫希霍恩综合征脊柱侧凸的治疗

Polish Annals of Medicine Pub Date : 2024-02-27 DOI: 10.29089/paom/177551

Artur Fabijan, B. Polis, Agnieszka Zawadzka-Fabijan, Michal Kolejwa, Kacper Wróbel, J. Kujawa, Remigiusz Kozłowski, Michał Marczak, Krzysztof Zakrzewski, E. Nowosławska

{"title":"A focused surgical case report: Managing scoliosis in Wolf–Hirschhorn syndrome","authors":"Artur Fabijan, B. Polis, Agnieszka Zawadzka-Fabijan, Michal Kolejwa, Kacper Wróbel, J. Kujawa, Remigiusz Kozłowski, Michał Marczak, Krzysztof Zakrzewski, E. Nowosławska","doi":"10.29089/paom/177551","DOIUrl":"https://doi.org/10.29089/paom/177551","url":null,"abstract":"Wolf–Hirschhorn syndrome (WHS) is a genetic disorder from a chromosomal deletion on chromosome 4, leading to systemic pathologies including spinal deformities like scoliosis.The objective of this publication is to present a case of scoliosis treatment in a patient with WHS, where the primary goal was to halt the progression of the curvature and achieve the most effective correction of the deformity, despite the guardians' refusal to extend the stabilization system to the pelvis.Preoperative radiographs revealed a single-curve scoliosis of 64°, as measured by the Cobb method between Th11 and L5. Prior to the scheduled procedure, a magnetic resonance imaging examination of the spinal column was conducted to potentially visualize any spinal cord pathology. A corrective procedure, posterior spinal fusion, was performed using cobalt-chrome rods. A postoperative posturographic control examination was conducted, and follow-up outpatient visits were recommended.Despite not implementing the stabilization system to the pelvis, a reduction in deformation by 22° was achieved, resulting in 42° measured between Th11 and L5. In a follow-up examination 18 months post-operation, the degree of deformity remained stable, maintaining the curvature angle of 42° measured between Th11 and L5.Treating scoliosis in patients with WHS requires a tailored approach, considering the specifics of their condition and utilizing optimal spinal stabilization methods. A multidisciplinary approach, integrating various therapeutic modalities, is crucial for enhancing the quality of life of WHS patients.","PeriodicalId":38569,"journal":{"name":"Polish Annals of Medicine","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140424455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Wojciech Rowiński (1935–2014) – a pioneer of Polish transplantology and a mentor 沃伊切赫-罗文斯基（1935-2014）--波兰移植学的先驱和导师

Polish Annals of Medicine Pub Date : 2024-02-27 DOI: 10.29089/paom/176219

Katarzyna Podhorodecka, Kruminis-Kaszkiel Ewa, Adadyński Leszek, Kędziora Bartosz, Wojtkiewicz Joanna, Kowalski Ireneusz

{"title":"Wojciech Rowiński (1935–2014) – a pioneer of Polish transplantology and a mentor","authors":"Katarzyna Podhorodecka, Kruminis-Kaszkiel Ewa, Adadyński Leszek, Kędziora Bartosz, Wojtkiewicz Joanna, Kowalski Ireneusz","doi":"10.29089/paom/176219","DOIUrl":"https://doi.org/10.29089/paom/176219","url":null,"abstract":"The present state of Polish transplantology and nephrology was created to a great extent by prof. Wojciech Rowiński due to his excellent organizational, clinical, and didactic skills. His major field of interest was the pathophysiology of the ischemic damage in donor organs; especially kidneys. Together with his colleagues, he was responsible for the implementation of hypothermic pulsatile perfusion in order to preserve a cadaveric kidney until it could be used in clinical practice. The procedure has been in use since 1995 and has been an extremely important achievement in the reduction of the incidence of posttransplant acute tubular necrosis.The purpose of our work is to introduce the reader to the person of Wojciech Rowiński.The work is based on the available literature. The search process resulted in the detection of relevant articles using valid keywords on electronic databases, including Embase, PubMed, Scopus, Web of Science, and Cochrane Library. Subsequently, 11 were identified as eligible for our review.In 2008, due to Rowiński's initiative, the Parliament of the Republic of Poland accepted a resolution regarding the approval of transplantation as a method of treatment.Rowiński's pioneering efforts and innovative techniques in transplantology had a profound impact on the field, leading to improved organ preservation, reduced complications, and enhanced ethical considerations.","PeriodicalId":38569,"journal":{"name":"Polish Annals of Medicine","volume":"66 s7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140426889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Poland syndrome: A case of difficult weaning of ventilation after surgery 波兰综合征：一例手术后难以断气的病例

Polish Annals of Medicine Pub Date : 2024-02-27 DOI: 10.29089/paom/178080

I. S. Mohamad, Idzman Idros, Sabrina Jane Dass, Mohammad Zawawi Yaacob, Voon Meng Leow

{"title":"Poland syndrome: A case of difficult weaning of ventilation after surgery","authors":"I. S. Mohamad, Idzman Idros, Sabrina Jane Dass, Mohammad Zawawi Yaacob, Voon Meng Leow","doi":"10.29089/paom/178080","DOIUrl":"https://doi.org/10.29089/paom/178080","url":null,"abstract":"Poland syndrome is a rare congenital anomaly that occurs in 1 in 30,000 children. It is characterised by unilateral underdevelopment or lack of the chest wall muscle that is apparent at birth. Rarely is it discovered to involve a bilateral chest muscular deficit. Poland syndrome presents in a wide variety of ways, which can often make diagnosis challenging.We would like to highlight the rarity of Poland syndrome, and the challenges of post-operative recovery, primarily the ventilation.We presented a case of a 44-year-old female with non-investigated chest wall deformity, whom required emergency surgical intervention under general anaesthesia. Post-operatively, she required prolonged ventilatory support, and was then diagnosed with Poland syndrome.The patient had undergone an emergency laparotomy and left lateral hepatectomy for left hepatolithiasis with liver abscess. Post-operation, she required prolonged ventilation, with gradual weaning of oxygen. Imaging studies showed absence of left pectoralis major, thus a diagnosis of Poland syndrome. Gradually she was weaned off and had a successful post operative recovery.Poland syndrome is a rare congenital abnormality. In patients undergoing general anaesthesia, the normal mechanics of breathing while ventilated are absent. Their recovery is longer and requires prolonged ICU admission.","PeriodicalId":38569,"journal":{"name":"Polish Annals of Medicine","volume":"86 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140426409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

What do parents of children know about food additives in selected foods? 儿童家长对特定食品中的食品添加剂了解多少？

Polish Annals of Medicine Pub Date : 2024-02-27 DOI: 10.29089/paom/181533

Paulina Polak, Weronika Osmala-Kurpiewska

{"title":"What do parents of children know about food additives in selected foods?","authors":"Paulina Polak, Weronika Osmala-Kurpiewska","doi":"10.29089/paom/181533","DOIUrl":"https://doi.org/10.29089/paom/181533","url":null,"abstract":"Food additives are used in foods by manufacturers to prevent unfavourable changes in colour, taste and smell and to extend shelf life. Consumption of highly processed products containing large amounts of food additives can lead to accumulation of these substances in the body and cause adverse health effects.The aim of the study was to assess parents' knowledge of selected food additives and their impact on the health of preschool children.The original survey was conducted in March 2022. In total, 112 parents of preschool children attending kindergartens in the Silesian Voivodeship were interviewed. The questionnaire consisted of information and 18 questions, including the respondents' awareness of the presence of food additives in food and their impact on human health. The survey results were prepared in Microsoft Office Excel 2019 and Statistica.It was found that less than half of those surveyed (45.53%) thought that the information provided on food additives was easy to understand. More than half of those surveyed (52.68%) did not know that the consumption of products with added benzoic acid can lead to hypersensitivity reactions in patients with bronchial asthma, allergic rhinitis and skin allergies.The potential health effects of consuming foods containing selected food additives were not known by most of the parents surveyed. Educational activities to increase parents' knowledge about food additives are recommended.","PeriodicalId":38569,"journal":{"name":"Polish Annals of Medicine","volume":"42 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140427318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0