B.B. Williams, K. Ichikawa, C. Kao, H. J. Halpem, Xiaochuan Pan
{"title":"Deblurring and noise suppression in spatial EPR imaging","authors":"B.B. Williams, K. Ichikawa, C. Kao, H. J. Halpem, Xiaochuan Pan","doi":"10.1109/NSSMIC.2002.1239629","DOIUrl":"https://doi.org/10.1109/NSSMIC.2002.1239629","url":null,"abstract":"Electron paramagnetic resonance (EPR) imaging has been used to map in vivo spatial distributions of endogenous and introduced free radicals. Because of the appreciable spectral linewidths of the radicals and the finite magnitude of the magnetic field gradients that encode spatial information, it is necessary to perform deblurring and noise suppression to achieve images with high spatial resolution. Recently, a regularized inverse-filtering technique for suppressing noise and blurring was described and evaluated for use with 3D single photon emission computed tomography. This filtering technique uses an a priori random image field (RIF) to specify the expected signal region and degree of smoothness in the image.","PeriodicalId":385259,"journal":{"name":"2002 IEEE Nuclear Science Symposium Conference Record","volume":"147 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2002-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114627798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Yoshida, T. Ohsugi, K. Yamamura, K. Yamamoto, K. Sato
{"title":"The easy way to reduce the surface radiation damage of silicon strip detectors","authors":"S. Yoshida, T. Ohsugi, K. Yamamura, K. Yamamoto, K. Sato","doi":"10.1109/NSSMIC.2002.1239391","DOIUrl":"https://doi.org/10.1109/NSSMIC.2002.1239391","url":null,"abstract":"We introduce two methods to reduce the surface radiation damage of silicon strip detectors. The microscopic reason of surface radiation damage is mainly due to the generation of radiation induced interface traps. The interface traps formation occurs as a result of a series of processes initiated by the creation of electron-hole pairs in SiO/sub 2/ layer and the subsequent transport of the holes to the SiO/sub 2//Si interface. To prevent the transport of holes to the SiO/sub 2//Si interface, we tried two different methods. The leakage current after irradiation decreased by 26% and 67% using these methods.","PeriodicalId":385259,"journal":{"name":"2002 IEEE Nuclear Science Symposium Conference Record","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2002-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114949664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Investigation of spatial resolution and efficiency using pinholes with small pinhole angle","authors":"M. Williams, A. Stolin, B. Kundu","doi":"10.1109/NSSMIC.2002.1239663","DOIUrl":"https://doi.org/10.1109/NSSMIC.2002.1239663","url":null,"abstract":"Pinhole collimators are well suited for small animal SPECT, in which high spatial resolution is required over a small field of view (FOV). Typical pinhole collimators have pinhole angles of 90/spl deg/ or more. If their full FOV is used, the trajectories of imaged gamma rays can be more than 45/spl deg/ away from the pinhole axis, and form angles of incidence at the surface of a planar detector greater than 45/spl deg/. The large incident angle produces a depth-of-interaction (DOI) blur thus reducing spatial resolution for these off-axis locations. This loss of resolution is masked by the accompanying improvement of the pinhole point spread function (PSF) due to the reduced effective aperture size. The magnitude of these effects as a function of the angle between the gamma ray trajectory and the pinhole axis depends on detector absorption efficiency, and on the physical parameters of the pinhole collimator, including pinhole type, composition, and size pinhole angle. In addition, the reduced effective pinhole results in reduced efficiency for off-axis source points. In this paper we investigate the angular dependence of these effects for pinhole collimators with different compositions and pinhole angles. Results are compared to theoretical expressions that take into account gamma ray penetration of the pinhole material.","PeriodicalId":385259,"journal":{"name":"2002 IEEE Nuclear Science Symposium Conference Record","volume":"239 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2002-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116394591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Initial investigation of circle-plus-arc orbit variants with a dedicated emission mammotomograph","authors":"C. Archer, M. Tornai, J. Bowsher, M. Bradshaw","doi":"10.1109/NSSMIC.2002.1239518","DOIUrl":"https://doi.org/10.1109/NSSMIC.2002.1239518","url":null,"abstract":"A dedicated emission mammotomograph, uniquely capable of imaging in a hemisphere, is utilized to image the breast by way of complex acquisition orbits, completely sampling most of the breast. Orbits such as the circle-plus-arc (CPA) in particular provide for extended viewing times in a specific portion of the breast. This is advantageous in that as a diagnostic rather than screening imaging tool, a long duration of the camera trajectory may be distinctly positioned in the quadrant where the lesion is suspected. However, orbit modifications that distribute the scan time more evenly over the breast may also be effective. As the trajectories conform to the shape of the breast, including dynamic radius-of-rotation control, resolution degradation is minimized. However, for both the arc and the circular portion of the orbit. increased background contamination may result since the line-of-sight of the single photon camera can view unscattered primary radiation, particularly from cardiac and hepatic sources. The effect of azimuthal position of the arc, as well as the degree of the arc, on image quality is investigated by measurements of lesion signal-to-noise ratios and contrasts. Additionally, because the resolution characteristics of the CPA are not uniform throughout breast quadrants, the implementation of a modified orbit, in the shape of a 3D cloverleaf is investigated through measurements of the breast phantom alone with lesions of varying radioactive concentrations, and with additional torso backgrounds. These initial results indicate that polar tilt does affect image quality, with low polar tilt showing little variation in SNRs and contrasts, while increasing tilt decreases SNRs and contrasts by /spl sim/2/spl times/ when torso background is present. Considering the effect of azimuthal arc location, /spl theta/=45/spl deg/ yields the highest SNRs and contrasts for the locations at which SNR was evaluated. Both cloverleaf orbits yield comparable SNRs and contrasts to the CPA orbits.","PeriodicalId":385259,"journal":{"name":"2002 IEEE Nuclear Science Symposium Conference Record","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2002-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124400224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T. Miyachi, N. Hasebe, H. Ito, T. Masumura, H. Yoshioka, N. Yamashita, O. Okudaira, T. Murakami, Y. Uchihori, M. Sato, T. Tou
{"title":"Study of low-Q PZT as a radiation detector","authors":"T. Miyachi, N. Hasebe, H. Ito, T. Masumura, H. Yoshioka, N. Yamashita, O. Okudaira, T. Murakami, Y. Uchihori, M. Sato, T. Tou","doi":"10.1109/NSSMIC.2002.1239257","DOIUrl":"https://doi.org/10.1109/NSSMIC.2002.1239257","url":null,"abstract":"Piezoelectric PZT elements were studied by directly irradiating a 400 MeV/n Xe beam. The elements were sensitive to the number of 10/sup 4/ Xe ions and their output amplitudes were proportional to the beam intensity, that is, the total energy deposited within the element. An ensemble of the output amplitudes behaved like the Bragg curve towards the end of the range. We discuss its potential as a radiation detector and its application to high intensity and high energy detectors.","PeriodicalId":385259,"journal":{"name":"2002 IEEE Nuclear Science Symposium Conference Record","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2002-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126152097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Detection of respiratory movement during SPECT/PET data acquisition","authors":"K. Tamagawa, K. Ogawa, M. Nakajima","doi":"10.1109/NSSMIC.2002.1239622","DOIUrl":"https://doi.org/10.1109/NSSMIC.2002.1239622","url":null,"abstract":"In the reconstruction of a myocardial SPECT or PET image, respiration causes serious blurring. The aim of this study is to compensate for this blurring by monitoring the movement of the thorax. The measurement should be done without touching the patient and with high accuracy. Our system uses a fiber-grating device (FGD) and an ITV camera for detecting the respiratory movement with images sequentially acquired during the data acquisition in SPECT or PET. When we project a laser beam onto the FGD, a dot-matrix pattern is created and these bright spots are projected onto an object. By monitoring a group of dot matrix patterns we can compensate for the position in which the gamma rays are being detected. In this paper we describe the preliminary results of a system for measuring respiratory movement with a fiber-grating vision sensor.","PeriodicalId":385259,"journal":{"name":"2002 IEEE Nuclear Science Symposium Conference Record","volume":"142 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2002-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124715566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. Macri, B. Donmez, L. Hamel, Manuel Julien, M. McClish, M. McConnell, R. S. Miller, J. Ryan, M. Widholm
{"title":"Readout and performance of thick CZT strip detectors with orthogonal coplanar anodes","authors":"J. Macri, B. Donmez, L. Hamel, Manuel Julien, M. McClish, M. McConnell, R. S. Miller, J. Ryan, M. Widholm","doi":"10.1109/NSSMIC.2002.1239356","DOIUrl":"https://doi.org/10.1109/NSSMIC.2002.1239356","url":null,"abstract":"We report progress in the study of CZT strip detectors featuring orthogonal coplanar anode contacts. The work includes laboratory and simulation studies aimed at optimizing and developing compact, efficient, high performance detector modules for 0.05 to 1 MeV gamma radiation measurements. The novel coplanar anode strip configuration retains many of the performance advantages of pixel detectors yet requires far fewer electronic channels to perform both 3-d imaging and spectroscopy. We report on studies aimed at determining an optimum configuration of the analog signal processing electronics to employ with these detectors. We report measurements of energy and spatial resolution in three dimensions for prototype 5 and 10 mm thick CZT detectors using a set of shaping and summing amplifiers.","PeriodicalId":385259,"journal":{"name":"2002 IEEE Nuclear Science Symposium Conference Record","volume":"106 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2002-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124814417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Design optimization of the PMT-ClearPET prototypes based on simulation studies with GEANT3","authors":"U. Heinrichs, U. Pietrzyk, K. Ziemons","doi":"10.1109/NSSMIC.2002.1239415","DOIUrl":"https://doi.org/10.1109/NSSMIC.2002.1239415","url":null,"abstract":"Within the Crystal Clear Collaboration four centres are developing 2/sup nd/ generation high performance small animal PET scanners for different kinds of animals and medical applications. The first prototypes are PMT-based systems including depth of interaction (DOI) detection by using a phoswich layer of LSO and LuYAP. The aim of these simulation studies is to optimize sensitivity and spatial resolution of given designs, which vary in FOVs caused by different detector configurations (ring/octagon) and sizes. For this purpose the simulation tool GEANT3 (CERN) was used. The simulations have shown that all PMT designs with one-to-one coupling of crystals have a very nonlinear axial sensitivity profile. By shifting every other PMT 1/4 of a PMT length in axial direction the sampling of the FOVs became more homogeneous. At an energy threshold of 350keV the regression coefficient increases from 0.818 for the non-shifted to 0.993 for the shifted design. Simulations of a point source centred in the FOV (threshold: 350keV) resulted in sensitivities of 4.2% for a 4/spl times/20PMT (LSO/LuYAP a 10mm) and 3.8% for a 4/spl times/16PMT (LSO/LuYAP a 8mm) ring design. The 3D-MLEM reconstruction of a point source shows the enormous improvement of resolution using a crystal double layer with DOI (3.1mm at 40mm from CFOV) instead of a 20mm single layer (11.9mm).","PeriodicalId":385259,"journal":{"name":"2002 IEEE Nuclear Science Symposium Conference Record","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2002-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124821707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. V. Narayanan, Matt A. King, P. H. Pretorius, S. Dahlberg, J. Leppo, N. Botkin, J. Krasnow, W. Berndt, E. C. Frey
{"title":"Evaluation of scatter compensation strategies and their impact on human detection performance in Tc-99m myocardial perfusion imaging","authors":"M. V. Narayanan, Matt A. King, P. H. Pretorius, S. Dahlberg, J. Leppo, N. Botkin, J. Krasnow, W. Berndt, E. C. Frey","doi":"10.1109/NSSMIC.2002.1239611","DOIUrl":"https://doi.org/10.1109/NSSMIC.2002.1239611","url":null,"abstract":"Human-observer receiver-operating characteristic (ROC) results with clinical patient studies indicate that ordered-subset expectation-maximization (OSEM) reconstructions with a combination of corrections for attenuation, scatter and distance-dependent resolution (DDR) significantly improves perfusion defect detection accuracy over FBP images. A recent Monte-Carlo study has also shown that for scatter correction (SC) in particular, selection of an appropriate strategy can impact cardiac uniformity. The spatial domain based effective source scatter estimation (ESSE) technique was shown to provide more robust performance in improving cardiac uniformity than the triple-energy window (TEW) method which is our current clinical standard for SC.","PeriodicalId":385259,"journal":{"name":"2002 IEEE Nuclear Science Symposium Conference Record","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2002-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129510454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Simulation of the output from a scintillator/photodiode detector using Monte Carlo techniques and spice circuit simulation","authors":"S. McCallum, P. Clowes, A. Welch","doi":"10.1109/NSSMIC.2002.1239465","DOIUrl":"https://doi.org/10.1109/NSSMIC.2002.1239465","url":null,"abstract":"We have developed a procedure to predict the output signal and system noise of various scintillator/photodiode detector combinations. The simulation is in three parts: 1. Monte Carlo techniques are used to model gamma ray interaction and light production in a scintillator 2. The current pulse generated from this light is then modeled, and finally 3. The simulation of photodiode and charge sensitive amplifier response and noise levels are made using a standard Spice package. To validate this procedure we have performed a series of simulations with a variety of scintillators and photodiodes. We have also built detectors in the laboratory to compare results simulated and measured results. Comparisons show good correlation between measured and simulated figures. Now this procedure has been developed and tested it will allow us to test and optimize scintillation detector designs quickly and efficiently.","PeriodicalId":385259,"journal":{"name":"2002 IEEE Nuclear Science Symposium Conference Record","volume":"61 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2002-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128220454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}