Indonesian Journal of Applied Research (IJAR)最新文献

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SAPPAN (Caesalpinia sappanL.) EXTRACT-BASED LABEL FOR DETECTION OF CHICKEN MEAT SPOILAGE 海参(Caesalpinia sappanL.)基于提取物的鸡肉腐败检测标签
Indonesian Journal of Applied Research (IJAR) Pub Date : 2021-12-08 DOI: 10.30997/ijar.v2i3.146
Muhammad Fakih Kurniawan, T. Fitrilia, Hikmah Nur Chosida, Nursyawal Nacing
{"title":"SAPPAN (Caesalpinia sappanL.) EXTRACT-BASED LABEL FOR DETECTION OF CHICKEN MEAT SPOILAGE","authors":"Muhammad Fakih Kurniawan, T. Fitrilia, Hikmah Nur Chosida, Nursyawal Nacing","doi":"10.30997/ijar.v2i3.146","DOIUrl":"https://doi.org/10.30997/ijar.v2i3.146","url":null,"abstract":"Brazilin in sappan is sensitive to pH, which make it possible as indicator of food quality. This research aimed to investigate performance of sappan extract as colorant for indicator label applied in chicken meat packaging. The samples were stored at room and refrigerator temperature. They were then tested for color change of label RGB (Red Green Blue), pH and TVB-N (Total Volatile Base-Nitrogen) of the meat. Data were analyzed using ANOVA at significant level of 5%. Indicator label showed the reduced RGB during storage, while pH and TVB-N increased. In case of room temperature, the color change into pink occurred in day 3 with pH 6.72 and TVB-N 1.84 mg N/100g. Meanwhile, for samples at refrigerator temperature, the label color turned into pink in day 6, with pH 6.56 and TVB-N 2.09 mg N/100g. In this regard, indicator label could detect the depletion of chicken meat quality as indicated by color shift from yellow to pink when pH and TVB-N were at critical value. This result provides significant output for development of sappan extract for indicator of meat spoilage.","PeriodicalId":381629,"journal":{"name":"Indonesian Journal of Applied Research (IJAR)","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115826993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
THE EFFECT OF CONCENTRATION AND FREQUENCY OF APPLICATION OF BANAN WEEVIL SOLUTION KEPOK ON RED CHILI 香蕉象鼻虫溶液kepok浓度和施用频率对红辣椒的影响
Indonesian Journal of Applied Research (IJAR) Pub Date : 2021-08-31 DOI: 10.30997/ijar.v2i2.141
Oktavianus Lumban Tobing, Yanyan Mulyaningsih, Raden Danuningrat
{"title":"THE EFFECT OF CONCENTRATION AND FREQUENCY OF APPLICATION OF BANAN WEEVIL SOLUTION KEPOK ON RED CHILI","authors":"Oktavianus Lumban Tobing, Yanyan Mulyaningsih, Raden Danuningrat","doi":"10.30997/ijar.v2i2.141","DOIUrl":"https://doi.org/10.30997/ijar.v2i2.141","url":null,"abstract":"The purpose of the study is to determine the effect of concentration and frequency of application of banana weevil solution kepok against red chili plants is roofed with translucent ultraviolet plastic 70% which acts as a natural growth regulator.  Research on the provision of banana weevil solution covered in 70% translucent ultraviolet plastic in open land has not been found before.    The growing regulators from the gibberellin and cytokinin groups were able to boost the growth and yield of chili peppers. The method of using a random design of factorial groups, as the first factor is age consists of 9 levels, namely T1: age (14) HSPT, T2: age (14.21) HSPT, T3: age (14,21,28) HSPT, T4: age (14,21,28, 35) HSPT, T5 : age (14,21,28,35, 42) HSPT, T6: age (14,21,28,35,42,49) HSPT, T7: age (14,21,28,35,42,49,56) HSPT, T8: age (14,21,28,35,42,49,56,63) HSPT, and control (T0). The second factor is concentration consists of 3 levels, namely K1 (30%), K2 (45%), and K0 (0%). The results of the study obtained concentration of K1 (30%) with the amount of T6 administration is the best result in vegetative growth of the plant height change, the number of branches, and the width of the header, while the concentration of K1 (30%) give the best results on the length of the fruit, the dry weight of the fruit, and the diameter of the fruit from other treatments. Conclusion of the application of concentration and frequency of the sea of banana weevil kepok containing regulatory substances growing on red chili plants in the field covered with ultraviolet plastic roof significantly increases the growth and yield of red chili peppers.","PeriodicalId":381629,"journal":{"name":"Indonesian Journal of Applied Research (IJAR)","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129212948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
CARCASS AND MEAT QUALITY CHARACTERISTICS OF WILD BOAR CROSSBREDS 杂交野猪胴体和肉质性状
Indonesian Journal of Applied Research (IJAR) Pub Date : 2021-08-25 DOI: 10.30997/ijar.v2i2.123
N. Gorkhali, Prashanna Koirala, S. Sapkota, A. Mishra, U. Subedi, D. Adhikari, Bhoj Raj Pokhrel, N. Bhattarai
{"title":"CARCASS AND MEAT QUALITY CHARACTERISTICS OF WILD BOAR CROSSBREDS","authors":"N. Gorkhali, Prashanna Koirala, S. Sapkota, A. Mishra, U. Subedi, D. Adhikari, Bhoj Raj Pokhrel, N. Bhattarai","doi":"10.30997/ijar.v2i2.123","DOIUrl":"https://doi.org/10.30997/ijar.v2i2.123","url":null,"abstract":"Due to the growing interest in the production and consumption of wild boar meat, the quality attributes of meat products should be well established. To characterize the quality of wild boar cross meat, two males and two females reared in the same environment were slaughtered at an average of one year of age, and meat samples were was collected and analyzed for different parameters such as for moisture, pH value, protein, fat, iron, phosphorous, calcium, water holding capacity through the measure of cooking loss. Data obtained for live body weight, carcass biochemical characteristics, and meat quality traits were submitted to one-way analysis of variance (ANOVA) using a general linear model (uni-variate) in Statistical Package for Social Sciences (SPSS) computer program and the level of significance was determined observing the probability value (p) obtained through ANOVA of respective traits. To study the association among nutritive values and body parts, Pearson’s correlation coefficients were determined using in Statistical Package for Social Sciences (SPSS) computer program. The pH values were found to be in the range of 5.78 to 5.90. Moisture, total ash, fat, and protein contents were observed to be in the range of 71.38 to 73.57 %, 0.89 to 1.10 %, 4.34 to 5.54 %, and 16.73 to 18.84 % respectively. Iron, phosphorous, and calcium content were found to be in the range of 1.94 to 2.94 mg/100g, 20.17 to 37.57 mg/100g, and 170.68 to 190.88 mg/100g respectively whereas cooking loss was in the range of 31.59 to 26.88 %. Sensory evaluation of meat samples was examined by a group of panelists according to the hedonic rating test. The consumer preference was similar to both types of meat samples (male and female). The overall acceptance; however, were higher in female samples than in male samples due to boar taint evident during the cooking or eating of pork derived from non-castrated male pigs once they reach puberty. The comparison of wild crosses among available commercial pigs and indigenous pigs is warranted for further studies with an appropriate and defined production system to obtain lean meat as per the consumer preferences which could be extensively used in commercial pig production to provide high-quality pork.","PeriodicalId":381629,"journal":{"name":"Indonesian Journal of Applied Research (IJAR)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130559549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
SUSTAINABLE LAKE/SITU MANAGEMENT 可持续湖泊/原位管理
Indonesian Journal of Applied Research (IJAR) Pub Date : 2021-08-13 DOI: 10.30997/ijar.v2i2.108
A. Pambudi
{"title":"SUSTAINABLE LAKE/SITU MANAGEMENT","authors":"A. Pambudi","doi":"10.30997/ijar.v2i2.108","DOIUrl":"https://doi.org/10.30997/ijar.v2i2.108","url":null,"abstract":"The increasingly advanced developmentnin the city of Bogor has an impact on the carrying capacity of the environment. One that is rarely in the spotlight is about the decreasing number of lakes in Bogor. In urb an areas such as Bogor City, local people refer to the lakes as situ or setu. The existence of these “Situ” \u0000affects the water system, both in this city and in the surrounding areas. Although “Situ” play a vital role in maintaining the balance of urban water systems, they have not received sufficient attention in the planning documents for the City of Bogor, both annual and medium-term documents. The rapid development of the city affects thequantity and quality of urban lake water in the city of Bogor. These “Situ continue to experience physical and ecological degradation which increases the threat to the health of the population of the city of Bogor. This situation shows that the site has not been managed and functioningnproperly. Human and natural disturbances such as encroachment, garbage disposal, and untreated waste have polluted “Situ” water and reduced its volume capacity. Most of the lakes in the city of Bogor experience disturbances in damaged environmental conditions. This paper seeks to examine th e condition of the “Situ” in Bogor City and its problems based on literature studies from previous researchers. The results of the research will provide recommendations based on scientific theories and existing regulations, both national regional regulations and regional regulations in Bogor City","PeriodicalId":381629,"journal":{"name":"Indonesian Journal of Applied Research (IJAR)","volume":"87 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126458024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
THE IMPLEMENTATION OF OCCUPATIONAL HEALTH AND SAFETY FOR PREGNANT WORKERS IN VARIOUS WORKPLACES 在各种工作场所对怀孕女工实施职业健康和安全措施
Indonesian Journal of Applied Research (IJAR) Pub Date : 2021-04-27 DOI: 10.30997/IJAR.V2I1.94
Aditira Dwi Hanani
{"title":"THE IMPLEMENTATION OF OCCUPATIONAL HEALTH AND SAFETY FOR PREGNANT WORKERS IN VARIOUS WORKPLACES","authors":"Aditira Dwi Hanani","doi":"10.30997/IJAR.V2I1.94","DOIUrl":"https://doi.org/10.30997/IJAR.V2I1.94","url":null,"abstract":"Pregnant workers have more health risks for health problems than other workers. There are different potential hazards in different workplaces. Occupational Health and Safety Programs need to be implemented for pregnant workers in order to avoid work related diseases in various workplaces. This study aims to determine the the implementation of occupational health and safety for pregnant workers in various workplaces. This study uses a qualitative method by conducting FGD (Focus Group Discussion) with pregnant women workers from various workplaces and in-depth interviews with occupational health and safety experts. Occupational health and safety programs have been implemented for pregnant workers such as the right to maternity leave, working hours arrangements, health insurance, and special protection for pregnant workers. However, there are some workplaces that still do not provide special protection for pregnant workers. Every workplace should pay more attention to the health and safety of pregnant workers as an effort to prevent occupational accidents and work related diseases","PeriodicalId":381629,"journal":{"name":"Indonesian Journal of Applied Research (IJAR)","volume":"53 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116361995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The POTENTIAL OF BUTTERFLY PEA FLOWER METHANOL EXTRACT AS AN ANTIOXIDANT BY IN SILICO 摘要利用二氧化硅研究了蝶豆花甲醇提取物作为抗氧化剂的潜力
Indonesian Journal of Applied Research (IJAR) Pub Date : 2020-12-28 DOI: 10.30997/ijar.v1i3.64
T. Fitrilia, Muhammad Fakih Kurniawan, Febryana Rahayu Kurniawati, T. Setiawan
{"title":"The POTENTIAL OF BUTTERFLY PEA FLOWER METHANOL EXTRACT AS AN ANTIOXIDANT BY IN SILICO","authors":"T. Fitrilia, Muhammad Fakih Kurniawan, Febryana Rahayu Kurniawati, T. Setiawan","doi":"10.30997/ijar.v1i3.64","DOIUrl":"https://doi.org/10.30997/ijar.v1i3.64","url":null,"abstract":"Abstract: Butterfly pea flower (Clitoria ternatea L.) is a flowering plant from the Fabecea family that can grow vines. Butterfly pea flower are known to have chemical components that can act as antioxidants. This study aims to predict the potential of active compounds from methanol extract of butterfly pea flower in inhibiting reactive oxygen species (ROS) based on bond affinity (∆G), the value of Root Mean Square Deviation (RMSD) and their interactions. The method used was a computational method with in silico technique. The software used was Autodock Vina with visualization using the Biovia Discovery Studio Visualizer 2020. The enzyme receptor was NADPH Oxidase (NOX) obtained from Protein Data Bank and the test ligands were a chemical compound from methanol extract of butterfly pea flower. The results of the in silico study showed that the NO had a innate ligand, namely the GTP ligand which has a ∆G value of -7.3 kcal/mol, an RMSD value of 3.1111 Å and the interaction with the receptor that involves the presence of hydrogen bonds. Based on the results of the analysis of 11 test ligands, the chemical component of caffeine was predicted to have the most potential in inhibiting ROS compounds with a value of ∆G -5.4, RMSD value of 1.328 Å and had the same amino acid residue in hydrogen bonding, namely ASP118, and GLY15. The test ligand had the ability to inhibit ROS compounds with a lower level of stability than the innate ligand. \u0000Keywords: antioxidant; butterfly pea flower; in silico; NADPH oxidase, ROS","PeriodicalId":381629,"journal":{"name":"Indonesian Journal of Applied Research (IJAR)","volume":"3 Sect Epidemiol State Med 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116545140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
FORMULATION OF LIQUID HAND SOAP MADE FROM NEEM SEED OIL AND LEMONGRASS ESSENTIAL OIL 由印楝籽油和柠檬草精油制成的洗手液配方
Indonesian Journal of Applied Research (IJAR) Pub Date : 2020-12-28 DOI: 10.30997/ijar.v1i3.79
Fina Uzwatania, Riska Surya Ningrum, Sri Resti O
{"title":"FORMULATION OF LIQUID HAND SOAP MADE FROM NEEM SEED OIL AND LEMONGRASS ESSENTIAL OIL","authors":"Fina Uzwatania, Riska Surya Ningrum, Sri Resti O","doi":"10.30997/ijar.v1i3.79","DOIUrl":"https://doi.org/10.30997/ijar.v1i3.79","url":null,"abstract":"The COVID-19 outbreak has overly emphasised the importance of handwashing with soap to reduce the spread of the virus. This study was conducted to formulate a liquid hand soap with neem oil and lemongrass essential oil as an natural antibacterial component. Three different concentrations of neem oil 5%; 10% and 15% and three different concentration of lemongrass essential oil (0.2%; 0.4%;0.6%) were formulated as liquid soap using coconut oil, castor oil and neem oil as its soap bases. The natural liquid soap was made by saponification reaction between oils and potassium hydroxide. The soap was evaluated for its pH value, density, foam stability, insoluble in alcohol content, free fatty acid and antibacterial activity. The results showed that the colour of the liquid soap was transparent with yellowish colored and had distinctive smell of neem oil. The pH values of the different formulated liquid hand soaps are within the accepted pH range of 4 - 10. The specific gravity was 1,083 – 1,088 g/ml. The foam stability range was 25.35% - 78.38%, respectively. The insoluble in alcohol content range were 0.14 – 0.4. The free caustic alkali range was  0.12 – 0.47.  The liquid hand soap can inhibit the growth of Staphylococcus aureus. The inhibition zone diameter of liquid hand soap was 1.98- 2.61 cm. It was therefore proven that neem oil and lemongrass essensial oil is effective as an antibacterial component in the formulation of liquid hand soap.","PeriodicalId":381629,"journal":{"name":"Indonesian Journal of Applied Research (IJAR)","volume":"86 ","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133753946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
PRODUCT ATTRIBUTES DETERMINE THE PREFERENCE OF HERBAL MEDICINE CONSUMERS 产品属性决定了草药消费者的偏好
Indonesian Journal of Applied Research (IJAR) Pub Date : 2020-12-24 DOI: 10.30997/ijar.v1i3.65
Himmatul Miftah, Ita Novita, Hasni Tsuwaibah, Mohammad A. Sunaryo
{"title":"PRODUCT ATTRIBUTES DETERMINE THE PREFERENCE OF HERBAL MEDICINE CONSUMERS","authors":"Himmatul Miftah, Ita Novita, Hasni Tsuwaibah, Mohammad A. Sunaryo","doi":"10.30997/ijar.v1i3.65","DOIUrl":"https://doi.org/10.30997/ijar.v1i3.65","url":null,"abstract":"Abstract: The emergence of a wide variety of herbal medicinal products requires marketers to better understand consumer behavior. The various brands offered make consumers tend to have certain preferences before making a purchase decision. This study aims to determine the attributes of herbal medicinal products that determine the level of consumer preference in the purchasing process and the closeness of the attributes to consumer preferences. The method used is interviews with consumers which are then processed with conjoint analysis to determine the attributes that are most important to consumers in making a purchase. The research concludes that the most important attributes in purchasing herbal medicine in order from the most important are the properties, price, expiration time and packaging. There is a close relationship between the combination of attributes studied and consumer preferences for herbal medicine. This study is limited to four attributes and does not use ranking ratings on the stimulus or combination of attributes, consumer behavior. The uniqueness of this study is to analyze the attributes simultaneously. \u0000  \u0000Keywords: Herbal medicine product attributes, consumer preferences, conjoin analysis, level of importance","PeriodicalId":381629,"journal":{"name":"Indonesian Journal of Applied Research (IJAR)","volume":"237 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131840695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
EFFECTS DRYING ON THE INDONESIAN CITRUS PEEL ANTIOXIDANT ACTIVITY 干燥对印尼柑橘果皮抗氧化活性的影响
Indonesian Journal of Applied Research (IJAR) Pub Date : 2020-12-22 DOI: 10.30997/ijar.v1i3.63
Nindya Atika Indrastuti, S. Aminah, S. Fauziah, D. Handayani
{"title":"EFFECTS DRYING ON THE INDONESIAN CITRUS PEEL ANTIOXIDANT ACTIVITY","authors":"Nindya Atika Indrastuti, S. Aminah, S. Fauziah, D. Handayani","doi":"10.30997/ijar.v1i3.63","DOIUrl":"https://doi.org/10.30997/ijar.v1i3.63","url":null,"abstract":"The high production and market demand of citrus fruits for household and industrial consumption make it peels one of the most abundant wastes found in the environment. On the other hand, citrus peel is well known for bioactive compounds that beneficial to human health, including phenolic, flavonoids, and antioxidants. Recently, citrus peel waste is starting to be used for food ingredients. The drying technique is one of the solutions that can be used for preserving citrus peel waste which has high water content. This study was objected to identifying the effect of the drying type (tray dryer and freeze dryer) on the antioxidant activity alteration of three citrus varieties that commonly cultivated in Indonesia, i.e. pummelo/jeruk Bali (C. maxima Herr.), mandarine citrus/jeruk keprok (Citrus reticulate) and sweet orange/tangerine/jeruk Medan (C. microcarpa L. and C. sinensis L.). The antioxidant activity was measured by calculating the IC50 value. The results showed ethanol extract of fresh mandarin citrus peels showed the lowest IC50 (14.46 ± 3.63 mg/mL) compared to fresh pummelo peels (26.48 ± 5.17 mg/mL) and fresh tangerine peels (16.94 ± 1.51 mg/mL). Tray dryer technique reduced the IC50 value of the peel extracts of pummelo, mandarine citrus and tangerine were 78.92%, 72.34%, and 79.69%, respectively. Whereas Freeze dryer drying reduced the IC50 value of pummelo, mandarine citrus and tangerine peel extracts were 59.21%, 69.43%, and 80.46%, respectively.  ","PeriodicalId":381629,"journal":{"name":"Indonesian Journal of Applied Research (IJAR)","volume":"69 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123484668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
THE POTENTIAL INHIBITION OF XANTHINE OXIDASE BY PHENOLIC AND FLAVONOIDS DATE (Phoenix dactylifera) WITH MOLECULAR DOCKING METHOD 用分子对接法研究黄酮类化合物对黄嘌呤氧化酶的潜在抑制作用
Indonesian Journal of Applied Research (IJAR) Pub Date : 1900-01-01 DOI: 10.30997/ijar.v2i2.129
A. Hasan, L. Ambarsari, Karichsa Hariana
{"title":"THE POTENTIAL INHIBITION OF XANTHINE OXIDASE BY PHENOLIC AND FLAVONOIDS DATE (Phoenix dactylifera) WITH MOLECULAR DOCKING METHOD","authors":"A. Hasan, L. Ambarsari, Karichsa Hariana","doi":"10.30997/ijar.v2i2.129","DOIUrl":"https://doi.org/10.30997/ijar.v2i2.129","url":null,"abstract":"Dates is fruit of palm trees that mostly grow in the Middle East. Dates contain phenolic acids and flavonoids that have antioxidants and potentially inhibit the ability of xanthine oxidase. The purpose of this research to determine the molecular interactions of xanthine oxidase by ligand of phenolic acids and flavonoids to inhibiting the production of uric acid. This research was conducted by site directed docking method. The size of the center of retardation used in this research is x = 26.569, y = 9.985, and z = 113.088 and the retardation volume of x = 14, y = 14, and z = 16. Inhibition by flavonoid and phenolic acid compounds has produces good inhibition strength shown by Gibbs free energy which is negative. The compound with the highest Gibbs free energy value is  the anthocyanins compound which is -7.3 kCal / mol, the value is higher than the comparator ligand, allopurinol. Based on the bond analysis that is formed, the best compound in inhibiting xanthine oxidase is syringic acid.","PeriodicalId":381629,"journal":{"name":"Indonesian Journal of Applied Research (IJAR)","volume":"52 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125226658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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