Annals of Clinical and Medical Case Reports最新文献_第7页

A New De Novo Mutation in Htra1 Gene Associated With Painful Ataxia, Developmental Delay, and Autistic Behaviors Symptoms in An Iranian Boy Through Whole Exome Sequencing Followed by Homology Modeling 通过全外显子组测序和同源性建模，发现伊朗男孩与疼痛性共济失调、发育迟缓和自闭症行为症状相关的Htra1基因新突变

Annals of Clinical and Medical Case Reports Pub Date : 1900-01-01 DOI: 10.47829/acmcr.2023.101905

Omarmel V, Sharafshah A, Lewandrowski Kai-Uwe, Assefi M

引用次数: 0

The Use of Essential Oils - Alpha and Β-Pinene in the Treatment of Covid-19 α和Β-Pinene精油在治疗Covid-19中的应用

Annals of Clinical and Medical Case Reports Pub Date : 1900-01-01 DOI: 10.47829/acmcr.2021.7903

A. A, A. J

引用次数: 2

The Physics of Darwinian Evolution 达尔文进化论的物理学

Annals of Clinical and Medical Case Reports Pub Date : 1900-01-01 DOI: 10.47829/acmcr.2023.102308

Kleinman A

引用次数: 0

Frequency of Pin Tract Infection Among Patients with Tibia Fracture Treated with AO External Fixator AO外固定架治疗胫骨骨折患者针道感染发生率分析

Annals of Clinical and Medical Case Reports Pub Date : 1900-01-01 DOI: 10.47829/acmcr.2023.101901

Inam M, Ullah S, Khan I, Zaman R, Ali MA, Shabir M

引用次数: 0

Metastatic Adrenocortical Carcinoma Presenting as Intracavitary Mass in Right Atrium: A Case Report 转移性肾上腺皮质癌在右心房表现为腔内肿块1例

Annals of Clinical and Medical Case Reports Pub Date : 1900-01-01 DOI: 10.47829/acmcr.2022.81103

N. A, Sadiq R, Zafar S

{"title":"Metastatic Adrenocortical Carcinoma Presenting as Intracavitary Mass in Right Atrium: A Case Report","authors":"N. A, Sadiq R, Zafar S","doi":"10.47829/acmcr.2022.81103","DOIUrl":"https://doi.org/10.47829/acmcr.2022.81103","url":null,"abstract":"1.1. Background: Adrenocortical carcinomas grow rapidly and tend to metastasize to liver and lungs and invade kidney, renal vein and Inferior vena cava (IVC). Cardiac metastases of the tumor is rare, less than 20 cases have been described and most of them occurred via direct extension through inferior vena cava into right atrium [1]. Endocardial Metastases from adrenocortical carcinoma presenting as an intracavitary growth in right atrium of heart without associated IVC involvement is very rare. 1.2. Case Presentation: We describe a case of 20 years old young male who presented to emergency with gradual worsening of dyspnea and facial swelling for last 6 months. Echocardiography showed a large Right atrial mass filling the whole chamber, attached to IAS (interatrial septum) via thin stalk suggestive of right atrial myxoma. Patient underwent resection of myxoma and histopathology proved it to be metastatic adrenocortical neoplasm. Whole body contrast enhanced CT scan showed primary large soft tissue mass lesion in right suprarenal location with metastatic bilateral lung metastases. On biochemical investigation associated hypercortisolemia was found. 1.3. Conclusion: Usually renal cell carcinomas spread intraluminally via inferior vena cava into the right atrium (reported in 1 % of tumors). Intracavitary presentation of metastatic adrenocortical carcinoma is very rare, and index case report was a similar presentation of a young male that underwent resection of intracavitary growth of right atrium (suspected as Myxoma), that came out to be metastatic adrenocortical carcinoma. In patients with advanced local or metastatic adrenocortical carcinomas, not amenable to surgical resection, cytotoxic chemotherapy may be attempted.","PeriodicalId":380321,"journal":{"name":"Annals of Clinical and Medical Case Reports","volume":"31 9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131991331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Thymectomy in Red Cell Aplasia - A Case Report 胸腺切除术治疗红细胞发育不全1例

Annals of Clinical and Medical Case Reports Pub Date : 1900-01-01 DOI: 10.47829/acmcr.2023.102102

Arthur dos Santos Sena, Adolpho de Barros e Silva de Oliveira, Maria Carolina Santos Malafaia Ferreira, Duílio Cabral da Costa Neto, César Freire de Melo Vasconcelos, Wolfgang William Schmidt Aguiar

{"title":"Thymectomy in Red Cell Aplasia - A Case Report","authors":"Arthur dos Santos Sena, Adolpho de Barros e Silva de Oliveira, Maria Carolina Santos Malafaia Ferreira, Duílio Cabral da Costa Neto, César Freire de Melo Vasconcelos, Wolfgang William Schmidt Aguiar","doi":"10.47829/acmcr.2023.102102","DOIUrl":"https://doi.org/10.47829/acmcr.2023.102102","url":null,"abstract":"1.1. Background: Pure Red Cell Aplasia (PRCA) is a very rare syndrome responsible for severe anemia due to absence or significant reduction of erythroid precursors in the bone marrow. It’s etiology is variable, ranging from a congenital disease to an acquired one. Secondary acquired PRCA may be associated with several conditions, including Thymic Tumors. 1.2. Case Presentation: A 42-year-old male presented to the Internal Medicine department with constitutional symptoms: non-intentional weight-loss, palpitations, somnolence. Clinical investigation showed a severe normocytic normochromic anemia, with significant reticulocytopenia. Due to clinical status, several blood transfusions were needed. Further investigation with bone marrow biopsy showed intact precursors for platelets and leukocytes, with absence of erythroid precursors; the primary diagnostic hypothesis was Pure Red Cell Aplasia, with no etiology well defined, however. In order to rule out other conditions, imaging scans were performed; the chest CT showed a large mediastinal expansive formation, compatible with Thymoma. Patient was submitted to Thymectomy by the Thoracic Surgery team, with posterior improvement of clinical and hemodynamic status. Even so, for definitive remission of the PRCA, a bone marrow transplant was needed. The patient was successfully treated and remains healthy so far.","PeriodicalId":380321,"journal":{"name":"Annals of Clinical and Medical Case Reports","volume":"52 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134225848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Frequency of Acute Compartment Syndrome in Closed Fractures of the Limbs 四肢闭合性骨折急性筋膜室综合征的发生率

Annals of Clinical and Medical Case Reports Pub Date : 1900-01-01 DOI: 10.47829/acmcr.2023.102203

Inam M, Hasbiallah Khan I, Shabir M, Ali MA

引用次数: 0

Genetic Work-Up for the Rare New Mutations Causing Musculoskeletal and Spine Pain 引起肌肉骨骼和脊柱疼痛的罕见新突变的基因研究

Annals of Clinical and Medical Case Reports Pub Date : 1900-01-01 DOI: 10.47829/acmcr.2023.101903

Omarmeli V, Assefi M, Sharafshah A, Darabi P, Lewandrowski KU

引用次数: 0

Investigation of Methylation Levels in COMT Gene Promoter among Smokers and Opium Addicted Individuals Undergoing Methadone Treatment 接受美沙酮治疗的吸烟者和鸦片成瘾者COMT基因启动子甲基化水平的研究

Annals of Clinical and Medical Case Reports Pub Date : 1900-01-01 DOI: 10.47829/acmcr.2023.101904

Mansouri N, Omarmeli V, Sharafshah A, Assefi M, Tomlinson T, Lester K, Browning Z, Lewandrowski KU

引用次数: 0

Investigation of Methylation Levels in OPRK1 Gene Promoter among Smokers and Opium-Addicts underwent Methadone Maintenance Treatment 吸烟者和鸦片依赖者美沙酮维持治疗中OPRK1基因启动子甲基化水平的研究

Annals of Clinical and Medical Case Reports Pub Date : 1900-01-01 DOI: 10.47829/acmcr.2023.101902

Mansouri N, Omarmeli V, Sharafshah A, Assefi M, Lewandrowski KU

引用次数: 0