{"title":"Association between Body Mass Index and Severity According of Classification of Thyroid Cancer","authors":"Song I Yang","doi":"10.47829/acmcr.2021.71603","DOIUrl":"https://doi.org/10.47829/acmcr.2021.71603","url":null,"abstract":"1. Abstract 1.1. Purpose: Obesity is associated with aggressive pathological features and poor clinical outcomes in breast and prostate cancers. However, the associations between excess weight and prognostic factors for thyroid cancer are uncertain. This study aimed to evaluate the associations between body mass index (BMI) and severity according of classification of thyroid cancer. 1.2. Methods: Retrospective analysis of 4485 patients with thyroid cancer was performed. Patients were grouped according to BMI (underweight, normal weight, overweight and obesity)-based World Health Organization standardized categories. Clinicopathological factors were analyzed and compared between normal and other groups. 1.3. Results: According to the results, 3789 patients were women (84.5%) and mean age was 47.1 years. 4338 patients (96.7%) were diagnosed with PTC. FTC were 115(2.6%), MTA ware 24(0.5%), ATC were 5(0.1%). There were no significant associations between BMI quartiles and Multifocality, cervical lymph node metastasis, or distant metastasis. Higher BMI were significantly associated with extrathyroidal extension of PTC (P < 0.001). And higher BMI were significantly associated with advanced TNM stage (P=0.005). 1.4. Conclusion: Increased BMI might elevate the risks of aggressive clinicopathological features of PTC, such as extrathyroidal invasion and advanced TNM stage. However, there were few cases except for PTC, which made it difficult to find statistically significant results. To confirm this result, further studies with long-term follow-up and more patients are required. 2. Introduction Recently, the incidence of thyroid cancer has been growing worldwide [1]. Higher prevalence of thyroid cancer can be explained in part by the fact that development and use of neck ultrasonography and ultrasound-guided fine-needle aspiration have led to increased diagnostic rate for asymptomatic thyroid cancer [2]. Additional aspects, such as changes in exposure to environmental factors, may also play a role in explaining such increase in prevalence. However, considering that increase in prevalence of thyroid cancer coincided with increased number of early cancer with small tumor size, as well as various tumor sizes and stages, it is suspected that there are other unidentified factors besides advances in diagnostic tools [3]. The main risk factors for thyroid cancer are exposure to ionizing radiation, a history of benign thyroid disease, and a family history of thyroid cancer [4, 5, 6]. Overweight and obesity, expressed as a high BMI, are possible risk factors for thyroid cancer Obesity is associated with onset and progression of many cancers, including those of esophagus, colon, kidney, breast, skin, rectum, and gallbladder [7]. Obesity is the second most common, preventable, and modifiable cause of carcinogenesis, after smoking, there is worldwide variation that is dependent on the different incidences of obesity [8]. Although obesity is a known risk factor for car","PeriodicalId":380321,"journal":{"name":"Annals of Clinical and Medical Case Reports","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127877943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"PET Imaging Performed Immediately After COVID 19 Vaccination: What A Radiologist Should Know","authors":"Pankaj S","doi":"10.47829/acmcr.2021.61902","DOIUrl":"https://doi.org/10.47829/acmcr.2021.61902","url":null,"abstract":"","PeriodicalId":380321,"journal":{"name":"Annals of Clinical and Medical Case Reports","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132814560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Case Report of Fever in Returned Traveller","authors":"Lwin Zt, J. Xu","doi":"10.47829/acmcr.2021.7401","DOIUrl":"https://doi.org/10.47829/acmcr.2021.7401","url":null,"abstract":"","PeriodicalId":380321,"journal":{"name":"Annals of Clinical and Medical Case Reports","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122423525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Pre-Neoplastic Lesion: A Case Study","authors":"Souza Vlb, Soares Alb","doi":"10.47829/acmcr.2023.101419","DOIUrl":"https://doi.org/10.47829/acmcr.2023.101419","url":null,"abstract":"The aim of this paper is to report a case of Actinic Dermatosis in an 8-year-old female adult dog with erythematous skin. In the clinical","PeriodicalId":380321,"journal":{"name":"Annals of Clinical and Medical Case Reports","volume":"82 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116731074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Khachnaoui- Zaafrane K, Bedel B, Chami M, Sigaudy S, Bilan F, Paquis- Flucklinger V
{"title":"Mandibulofacial Dysostosis Guion-Almeida Type: A Syndrome to Recognize in Prenatal","authors":"Khachnaoui- Zaafrane K, Bedel B, Chami M, Sigaudy S, Bilan F, Paquis- Flucklinger V","doi":"10.47829/acmcr.2021.71001","DOIUrl":"https://doi.org/10.47829/acmcr.2021.71001","url":null,"abstract":"Khachnaoui-Zaafrane K1*, Bedel B2, Chami M2,3, Sigaudy S4, Bilan F5,6 and Paquis-Flucklinger V1 1Université Côte d’Azur, Inserm U1081, CNRS UMR7284, IRCAN, CHU de Nice, Nice, France 2Department of Prenatal Diagnosis, Nice University Hospital, Nice, France 3Cabinet de Radiologie les Elfes, Cannes, France 4Département de Génétique Médicale Hôpital Timone Enfant, 13385 Marseille cedex 5, France 5Laboratoire de Génétique Biologique, Service de Génétique, CHU de Poitiers, France 6Laboratoire de Neurosciences Cliniques et Expérimentales-INSERM U1084-Université de Poitiers, France","PeriodicalId":380321,"journal":{"name":"Annals of Clinical and Medical Case Reports","volume":"51 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126018682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Incidence of Periphral Neuropathy in Breast Cancer Women on Paclitaxel","authors":"Hasan Dam, Sahib As, Al-Rokan Aah, Mohsin Kk","doi":"10.47829/acmcr.2023.102405","DOIUrl":"https://doi.org/10.47829/acmcr.2023.102405","url":null,"abstract":"","PeriodicalId":380321,"journal":{"name":"Annals of Clinical and Medical Case Reports","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123120632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
W. Z., F. J, Ma H, C. X, Zhong Q, Hou L, Huang J, W. R, Shen X
{"title":"Protection of the External Branch of the Superior Laryngeal Nerve in Transoral Endoscopic Thyroidectomy Vestibular Approach (TOETVA): An Observational Study","authors":"W. Z., F. J, Ma H, C. X, Zhong Q, Hou L, Huang J, W. R, Shen X","doi":"10.47829/acmcr.2021.61301","DOIUrl":"https://doi.org/10.47829/acmcr.2021.61301","url":null,"abstract":"","PeriodicalId":380321,"journal":{"name":"Annals of Clinical and Medical Case Reports","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131188858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"One Cause of Alzheimer’s Disease: Gonorrhea and HSV-1","authors":"C. Pte","doi":"10.47829/acmcr.2020.5201","DOIUrl":"https://doi.org/10.47829/acmcr.2020.5201","url":null,"abstract":"In this paper we show that a portion (1/10) of Alzheimers Disease patients have as a combination of Gonorrhea, HSV-1, and Neonatal Conjunctivitis. In previous papers, I suggested that AD is caused by either Gonorrhea or HSV-1. No Herein we combine them. The biostatistics works out perfectly well. We also introduce the Game of Life Physics that can be used to show that Cell death is the result of one mathematical law.","PeriodicalId":380321,"journal":{"name":"Annals of Clinical and Medical Case Reports","volume":"126 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133796313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Fathi, H. Katzberg, C. Barnett, H. Sadeghian, V. Bril
{"title":"Cardiac Transplantation in Patients with Muscular Dystrophy: A Case Report and Review of Literature","authors":"D. Fathi, H. Katzberg, C. Barnett, H. Sadeghian, V. Bril","doi":"10.47829/acmcr.2021.71602","DOIUrl":"https://doi.org/10.47829/acmcr.2021.71602","url":null,"abstract":"1. Abstract We report a case of slowly progressive Becker’s muscular dystrophy in a 52-year-old man who required cardiac transplantation for intractable congestive heart failure. A referral was made concerning prognosis of his muscular dystrophy in the multidisciplinary approach to transplant. A review of the literature provides limited guidance on cardiac transplantation in patients with muscular dystrophy although this procedure appears to be well-tolerated in those with Becker’s muscular dystrophy. Formal assessments and neuromuscular follow-up have not been clearly documented in patients having cardiac transplantation, and robust clinical evidence or guidance in this area is lacking. 2. Introduction Muscular dystrophies are a heterogeneous group of genetic muscular disorders presenting with progressive muscular weakness which have characteristic pathological features in the muscle biopsy and are often associated with other organ involvement such as cardiac, respiratory, or central nervous system [1, 2]. Cardiac involvement can involve primarily the myocardium or conductive system or be secondary to respiratory muscle involvement by causing cor pulmonale [3, 4]. Improved management of respiratory, cardiac, and other complications in different types of muscular dystrophy (MD) has led to increased survival of with many patients surviving into adulthood [2, 3, 5, 6]. With increased life expectancy of MD patients, neuromuscular physicians may be asked to provide advice in novel areas that lack a solid evidence base or guideline. Here, we report the case of a 52-year-old Becker muscular dystrophy (BMD) patient evaluated at the request of the cardiology service regarding eligibility for cardiac transplantation. We also present the results of a literature review regarding cardiac transplantation in MD, including any consensus recommendations. 3. Case Report A 52-year-old man was first evaluated in the Prosserman Family Neuromuscular Clinic at age 41 for proximal lower limb weakness manifest as difficulty in climbing stairs. He reported that he had a normal childhood and development but that he was never athletic. His 74-year-old mother had difficulty climbing stairs starting at age 72 and examination showed that she had bilateral calf hypertrophy. Three of his sisters are healthy. He developed symptoms at age 28 with minimal difficulty in climbing stairs. The weakness progressed slowly and by age 37, he had difficulty getting up from a chair and required support to climb stairs. He had no other weakness, bulbar or respiratory symptoms. Physical examination revealed a normal cranial nerve examination and upper limb power. In the lower limbs, he had proximal weakness at 4/5 in hip flexors, quadriceps, and hamstrings, normal distal strength and bilateral calf hypertrophy. Deep tendon reflexes were reduced in the upper limbs, absent at the knees and normal at the ankles. Plantar reflexes were flexor. Sensory examination was normal. He had a waddling gait","PeriodicalId":380321,"journal":{"name":"Annals of Clinical and Medical Case Reports","volume":"260 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132907029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hatano M, K. I, Nakamura M, Isawa K, S. T, H. J., Sawa N, Yamamoto S, Ubara Y
{"title":"Tamoxifen May Have a Negative Effect on Bone Mineral Density in Fanconi Syndrome-Related Osteomalacia","authors":"Hatano M, K. I, Nakamura M, Isawa K, S. T, H. J., Sawa N, Yamamoto S, Ubara Y","doi":"10.47829/acmcr.2021.7901","DOIUrl":"https://doi.org/10.47829/acmcr.2021.7901","url":null,"abstract":"Tamoxifen May Have a Negative Effect on Bone Mineral Density in Fanconi Syndrome-Related Osteomalacia Hatano M, Kitajima I, Nakamura M, Isawa K, Suwabe T , Hoshino J , Sawa N Yamamoto Sand Ubara Y Department of Orthopaedic Surgery, Toranomon Hospital, Tokyo, Japan Department of Nephrology and Rheumtology, Toranomon Hospital, Tokyo, Japan Okinaka Memorial Institute for Medical Research, Toranomon Hospital, Tokyo, Japan","PeriodicalId":380321,"journal":{"name":"Annals of Clinical and Medical Case Reports","volume":"453 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125786053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}