Journal of Comprehensive Pediatrics最新文献

{"title":"Epidemiology of Diseases and Mortality in a Pediatric Intensive Care Unit in Qazvin, Iran","authors":"Z. Pirzadeh, M. Jamshidi, B. Arad","doi":"10.5812/compreped-122885","DOIUrl":"https://doi.org/10.5812/compreped-122885","url":null,"abstract":"Background: Depending on the level of care and the availability of pediatric intensive care unit (PICU) facilities, the mortality rate of acutely ill children varies in PICUs. Referral of patients from other medical centers, admission during working or off-work hours, and nosocomial infections are the most important risk factors for the high mortality rates in PICUs. Objectives: The present study aimed to investigate the characteristics and factors related to the risk of mortality in pediatric patients admitted to the PICU of a pediatric hospital in Qazvin, Iran. Methods: This cross-sectional study was performed on children admitted to the PICU of a pediatric hospital in Qazvin, Iran, between June 2017 and June 2020. During this period, a total of 1504 children, aged one month to 13 years, were admitted to the PICU, and 106 cases expired. The patients’ clinical data (ie, demographic characteristics, underlying disease, cause of death, and length of hospital stay) was extracted from their medical records. A prolonged length of stay was defined as more than 28 days of PICU admission. Results: A total of 106 children, with a mean age of 3.89 ± 3.23 years, expired during the study, with 41 (38.7%) cases being male. Among the investigated cases, 61 (57%) were < 2 years, 18 (17%) were 2 - 5 years old, and 27 (26%) were ≥ 6 years. In these patients, sepsis (13/82, 15.85%) and pneumonia (10/82, 12.19%) were the main causes of death. Other mortalities (14/106) were due to infectious diseases (gastroenteritis, influenza, and coronavirus disease) and non-infectious diseases (aspiration, anaphylaxis, and electrocution). The majority of children with a prolonged length of stay were < 2 years (17/23, 74%). The length of PICU stay was shorter in children with a lower weight percentile (P = 0.016). Conclusions: Following infectious diseases, congenital abnormalities and genetic disorders were the most common causes of pediatric mortality. Chronically ill children were more likely to be underweight and develop nutritional disorders, leading to the deterioration of their condition.","PeriodicalId":37929,"journal":{"name":"Journal of Comprehensive Pediatrics","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44785664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Efficacy and Safety of Enkephalinase Inhibitor Racecadotril in Treatment of Acute Diarrhea in Children: A Randomized Clinical Trial","authors":"Sheri Seyed Motahari, F. Imanzadeh, Amir Hossein Hosseini, N. Dara, K. Khatami, Ghazal Zahed, Negar Imanzadeh, Samane Sadeghi, A. Sayyari","doi":"10.5812/compreped-127104","DOIUrl":"https://doi.org/10.5812/compreped-127104","url":null,"abstract":"Background: Acute diarrhea in children with an annual prevalence of about 2 billion episodes accounts for 1.9 million deaths in developing countries. According to the World Health Organization (WHO), only 35% of children with diarrhea receive proper treatment for dehydration; hence, the detection of appropriate interventions enables us to prevent mortality and decrease the morbidity rate. Methods: This prospective randomized clinical trial was conducted from September 2018 to May 2019 in the Pediatric Gastroenterology Ward at the Mofid Children's Hospital, where 95 children were hospitalized with non-exudative acute gastroenteritis and moderate to severe dehydration. Among these patients, 53 children were administered intravenous (IV) fluid therapy and oral rehydration solution (ORS), and 42 children received IV rehydration and ORS plus Racecadotril (ORS+R). Daily bowel movements and their consistency were recorded at admission, 24 hours, and 48 hours after hospitalization. All data were analyzed by SPSS software version 25. Results: There was no statistically meaningful difference between the intervention and control groups in terms of age, gender, and weight. According to the statistical analysis, the dehydration severity was same in both groups, and no difference was revealed between the two groups regarding fever and vomiting. All laboratory findings were similar in both groups at the time of admission. Although the average duration of diarrhea was shorter in the racecadotril group than in the control group, there was no statistically significant difference between the two groups. The results indicated a rapid decline in the number of bowel movements by the first and second days after beginning of the treatment in both groups; however, no statistically meaningful difference was noticed. The present results indicated no significant difference between the two groups regarding the recovery rate in the first 24 hours of treatment. Moreover, although the recovery rate of children treated for 48 hours was faster in the racecadotril+ORS group than in the oral rehydration group, no significant difference was revealed. Conclusions: There was no meaningful relationship between the administration of racecadotril with the duration of diarrhea, the frequency of diarrhea, and the recovery rate in the first and second days after treatment. However, in 24 and 48 hours after treatment, there were a decrease in the number of watery stools and an increase in solid stools; hence, further studies with larger sample sizes and more accurate measurements determining factors affecting acute diarrhea and differentiating different types of diarrhea are recommended to further illustrate the role of racecadotril on the treatment of diarrhea in children.","PeriodicalId":37929,"journal":{"name":"Journal of Comprehensive Pediatrics","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47371261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of Video Education on Mothers' Knowledge of Hazard Factors and First Aid Administration in Choking Incidents","authors":"N. Sarabi, Mahnaz Nosratabadi","doi":"10.5812/compreped-121420","DOIUrl":"https://doi.org/10.5812/compreped-121420","url":null,"abstract":"Background: Choking is one of the most common types of unintentional injury that results in the death of children aged under 14 years. Objectives: This study aimed to assess the effect of providing mothers with video education on their awareness of choking hazards as well as methods of administering first aid to children aged between 6 months to 8 years. Methods: In this quasi-experimental study conducted from October to April 2021 in Dezful city of Iran, 110 mothers were divided into intervention and control groups by adopting convenience sampling method. The education program was run by offering two video presentations. Participants in both groups were asked to complete two questionnaires in order to evaluate their knowledge about first aid for choking children before and 30 days after the intervention. Data were analyzed based on frequency and Wilcoxon test using SPSS 16 software. Results: Mothers were found to have a very limited knowledge about the issues, including the right age for beginning chewing and smashing solid food in children, the most common food resulting in choking, and the best way to assess the risk of an object leading to choking of a child under the age of four. Furthermore, 10.9% of the mothers in the intervention group, as well as 12.7% of them in the control group were discovered to adopt Heimlich maneuver when facing the choking accident. The given percentages reached 67.3% and 16.4% in the intervention and control groups, respectively, after providing the mothers with proper training. Only 16.4% of mothers in the intervention group and 18.2% of them in the control group demonstrated the required knowledge of opening the airway in infants before the intervention. After offering the video education, however, this knowledge was increased by 68.5% and 20% in the intervention group and control group, respectively. Their knowledge of the risk factors for choking in control group (P = 0.000) and intervention group (P = 0.001) was significant before and after offering the video education; regarding the methods of administering first aid for choking children, however, the result was significant only in the intervention group (P = 0.000). Conclusions: Educating mothers may have improved their knowledge about the risk factors as well as the methods of dealing with choking children.","PeriodicalId":37929,"journal":{"name":"Journal of Comprehensive Pediatrics","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46690293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Quality of Life in Patients with Cystic Fibrosis Regarding Smoking History in Parents","authors":"S. Eslampanah, Maryam Hassanzad, Ali Valinejadi, H. Ghaffaripoor, M. Boloursaz, S. Mahdaviani, Noushin Baghaei, Z. Daneshmandi, A. Velayati","doi":"10.5812/compreped-122110","DOIUrl":"https://doi.org/10.5812/compreped-122110","url":null,"abstract":"Background: The provision of facilities to achieve better living conditions for patients with cystic fibrosis (CF) is of particular importance. Smoking is one of the known factors that aggravate CF. However, the effects of exposure to secondhand smoke (consumed by parents) if not consumed by the individual him/herself are not very evident. Objectives: This study aimed to evaluate the quality of life in patients with CF based on a history of smoking in parents. Methods: This cross-sectional analytical study was conducted on 100 patients with CF referred to the National Research Institute of Tuberculosis and Lung Diseases in Tehran, Iran, who were admitted in 2019 - 2021, using convenience sampling. After measuring height and weight, body mass index (BMI) was calculated, and the relationship between these factors (including a family history of smoking, pulmonary function tests, and BMI) with the quality of life of these patients was assessed. The data collection tool was a questionnaire. Data analysis was performed using SPSS software (version 20). The independent t-test and Pearson correlation test were used in this study, with a significance level of 0.05. Results: There was no statistically significant difference in the quality of life of the patients in the two groups whose parents were smokers and nonsmokers; however, physical and social functions and disease severity were lower in the smoking family group than in the other group (P > 0.05). In this study, there was no significant relationship between the quality of life of patients with CF in physical, emotional, and social functions and disease severity with a family history of smoking (P > 0.05); nevertheless, the quality of life was lower in patients whose fathers were smokers. In the present study, there was no significant relationship between patients’ quality of life in the smoking family group with the number of daily consumption of tobacco (cigarettes) in those around and the duration of family smoking (year). Conclusions: The findings of this study showed that smoking reduces the quality of life of patients with CF. Therefore, the need for the attention of parents and relatives of patients with CF to increase patients’ quality of life is seriously felt. There was no statistically significant relationship between smoking in patients with CF and reduced quality of life in this study; however, it is suggested to perform this study on a larger sample and in different cities in patients with CF and compare the results.","PeriodicalId":37929,"journal":{"name":"Journal of Comprehensive Pediatrics","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48061633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anxiety Disorders in Children with Functional Constipation: A Case-Control Study","authors":"Reza Saber Sangari, M. Hashemi, B. Salehi, P. Yousefichaijan, M. Rafiei, M. Rezagholizamenjany","doi":"10.5812/compreped.119997","DOIUrl":"https://doi.org/10.5812/compreped.119997","url":null,"abstract":"Background: Functional constipation is a common disorder in children, and evidence suggests that psychiatric disorders may induce functional constipation in children. The present study aimed to evaluate and compared anxiety disorders in children with and without functional constipation. Methods: This case-control study was conducted on 200 children (100 cases with functional constipation and 100 children without functional constipation) aged 15 - 8 years. The participants’ age and gender were evaluated and compared in two groups. Moreover, the Spence Children Anxiety Scale (SCAS) (parent form) for children was completed. Finally, the collected data were analyzed using SPSS software version 24. Results: Of 200 evaluated cases in the case and control groups, there were 46 (46.0%) and 59 (59.0%) males, respectively (P = 0.113). The mean ± SD of age in total, the case, and the control groups were 7.51 ± 1.91, 7.61 ± 0.91, and 7.41 ± 2.49 years, respectively (P = 0.585). Furthermore, SCAS in the case group was significantly higher (33.06 ± 14.4 vs. 24.8 ± 14.9, P = 0.001). Furthermore, the mean of separation anxiety disorder (P = 0.001), generalized anxiety (P = 0.003), and obsessive-compulsive disorder (OCD) were significantly higher in the functional constipation group (P = 0.001). Conclusions: Anxiety was higher in children with functional constipation than in children without functional constipation (ie, control group), among which separation anxiety, generalised anxiety, and OCD were significantly different in the two groups.","PeriodicalId":37929,"journal":{"name":"Journal of Comprehensive Pediatrics","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46805942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cerebral Infarction Following Correction of Aortic Coarctation Surgery in Children","authors":"A. Mirshahi, Siavash Kafian, H. Riasi, F. Salehi","doi":"10.5812/compreped.119717","DOIUrl":"https://doi.org/10.5812/compreped.119717","url":null,"abstract":"Background: Coarctation of the aorta (CoA) is a congenital heart defect. Due to the narrowing of the descending aorta, blood flow mainly reduces after the stenosis, and CoA can occur at any region in the thoracic and abdominal aorta. Cardiac surgeons and cardiologists are familiar with postoperative complications of CoA; however, there are also some other complications that have not been reported to date. Case Presentation: The present study investigated three cases of CoA undergoing reconstructive surgery. Nevertheless, a couple of days after the surgery, they manifested symptoms suspected of cerebral infarction. Ischemic infarction was observed after performing brain computed tomography. Additionally, we discuss possible pathophysiology and reasons that can lead to this problem. Conclusions: In this case series, we presented three cases of CoA patients who underwent reconstructive surgery and manifested cerebral infarction as an adverse effect of the reconstructive surgery.","PeriodicalId":37929,"journal":{"name":"Journal of Comprehensive Pediatrics","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41768516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Conference Abstracts: 17th Congress of Pediatric Emergencies and Common Diseases, Tehran, Iran (12 - 17 December 2021)","authors":"M. Nasehi","doi":"10.5812/compreped.124167","DOIUrl":"https://doi.org/10.5812/compreped.124167","url":null,"abstract":"<jats:p />","PeriodicalId":37929,"journal":{"name":"Journal of Comprehensive Pediatrics","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45079080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of the Effects of Salbutamol, Epinephrine, and 5% Inhaled Hypertonic Saline on Infants with Acute Bronchiolitis","authors":"L. Barati, Seyed Ali Mousavi Khosravi, S. Ariannejad, Ali Ahani Azari, Lobat Shahkar","doi":"10.5812/compreped.120489","DOIUrl":"https://doi.org/10.5812/compreped.120489","url":null,"abstract":"Background: Bronchiolitis is a lower respiratory tract infection and one of the major health concerns and hospitalization factors in infants. Objectives: This study aimed to address inconsistencies in treating this disease. Methods: This study is a double-blind clinical trial investigating the effect of salbutamol, epinephrine, and 5% inhaled hypertonic saline on treating infants with bronchiolitis referred to the Taleghani Pediatrics Hospital in Gorgan, Iran, during 2019 - 2020. The clinical results of the treatments and hospitalization stay were also evaluated. Results: In this study, the study sample encompassed 18 girls and 39 boys. There was no significant difference between the three groups regarding age, gender, parental literacy level, and history of allergies. Salbutamol and epinephrine, in comparison to hypertonic saline, were effective in shortening patients' hospital stay (P = 0.004). Moreover, there was a significant difference between the oxygen saturation of in the patients 48 h after treatment in the salbutamol and epinephrine groups compared to the saline group (P = 0.001). Conclusions: In comparison to hypertonic saline, salbutamol and epinephrine can be selected to treat children with acute bronchiolitis since they can shorten hospital stay improve O2 saturation, and decrease treatment costs imposed on the health care system and families.","PeriodicalId":37929,"journal":{"name":"Journal of Comprehensive Pediatrics","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43811577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Vitamin D Administration During Pregnancy on Neonatal Anthropometric Results and Apgar Score","authors":"S. Ekmen, Mehtap Çelik, Murvet Tuba Ayan","doi":"10.5812/compreped.120030","DOIUrl":"https://doi.org/10.5812/compreped.120030","url":null,"abstract":"Background: This study aims to determine the effects of vitamin D administration throughout pregnancy on the level of vitamin D in cord blood, neonatal anthropometric measurements, and Apgar score. Methods: This study was designed as a retrospective analytic study. The intervention group comprised 40 pregnant women who were prescribed vitamin D supplementation during their pregnancy, according to the recommendations of the Turkish Ministry of Health General Directorate of Mother and Child Health and Family Planning (MCHFP) and their infants, while the control group comprised 40 pregnant women without vitamin D supplementation and their infants. After exclusion criteria were applied, a total of 60 pregnant women and their babies (28 with supplementation, 32 without) were included in the final analyses. Results: Final analyses were conducted on 28 pregnant women and their infants as the intervention group and 32 pregnant women and their infants as the control group. The cord blood vitamin D values of the intervention group were significantly higher compared to controls (X2 = 25.71, P = 0.000). Vitamin D use throughout the pregnancy was observed to significantly increase vitamin D levels in the cord blood compared to those without supplementation. Vitamin D levels were categorized as normal in the cord blood of 53.6% of the pregnant women using vitamin D and 3.1% of the pregnant women not using vitamin D. However, there was no difference between the two groups in terms of neonatal anthropometric measurements and Apgar scores. Conclusions: Although cord blood 25(OH) vitamin D levels were significantly higher in the intervention group, there was no difference in neonatal outcomes. The fact that cord blood vitamin D levels were lower than 30 ng/mL in all samples suggests that the adequacy of the vitamin D supplementation recommended by TR Ministry of Health MCHFP during pregnancy should be discussed.","PeriodicalId":37929,"journal":{"name":"Journal of Comprehensive Pediatrics","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42671453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of the Iodine Status Among Iranian School-aged Children 20 Years After the First National Survey in Iran","authors":"A. Mokari, Z. Abdollahi, S. Sadeghian, Farid Nobakht, Ammar Salehi, H. Eini-Zinab","doi":"10.5812/compreped.121588","DOIUrl":"https://doi.org/10.5812/compreped.121588","url":null,"abstract":": In 1994, the mandatory iodized salt consumption became a law in Iran, and since then, almost all people have routinely and effectively received iodine. This study aimed to compare the iodine sufficiency among Iranian students in 1996 and 2017. We used Iran’s health ministry national data on urinary iodine among 8- to 10-year-old students. A total 13,389 and 2,917 urine samples were examined for monitoring in 2017 and 1996, respectively. The median urinary iodine (MUI) excretion of samples was 18.26 µg/dL in 2017 and 20.5 µg/dL in 1996. Based on the urinary iodine index (< 10 μg/dL), 14.53% and 19.61% of students had iodine deficiency (ID) in 1996 and 2017, respectively, which mild, moderate, and severe insufficiency was 8.83%, 2.3%, and 3.43% in 1996 and 14.86%, 3.72% and 1.01% in 2017. So, the main achievement of this national program was the reduction in severe ID rate during these years (3.43% vs. 1.01%).","PeriodicalId":37929,"journal":{"name":"Journal of Comprehensive Pediatrics","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46964602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}