{"title":"Separation of Diastereomers Taking Advantage for the Kinetic Control and Structure of Resolving Agent","authors":"Dombrády Zs, E. Pálovics, E. Fogassy","doi":"10.29011/2639-4685.100023","DOIUrl":"https://doi.org/10.29011/2639-4685.100023","url":null,"abstract":"The preparation of pure enantiomers of (1-methyl-2-phenyl)-ethylamine (A) is described. The resolution of racemic compound (A) was accomplished using half equivalent of tartaric acid. The purification of enantiomeric mixtures by a nonusual method are also described. Introduction The enantiomers of (1-methyl-2-phenyl)-ethylamine (A) (Figure 1) have not only therapeutical effect, but they could be important base material both for the pharmacetical industry and the organic chemical research (eg. for preparation of the Selegiline [1], Tamsulozine [2], or for other types of molecules). Our aim was to work out an effective, quick and practicable resolution method of racemic compound 1-phenylpropane-amine (A) to obtain the pure enantiomers.","PeriodicalId":378827,"journal":{"name":"Current Research in Bioorganic & Organic Chemistry","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115753322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}