{"title":"Spectral analysis of heart rate variability during trigger point acupuncture.","authors":"Yoji Kitagawa, Kenichi Kimura, Sohei Yoshida","doi":"10.1136/acupmed-2013-010440","DOIUrl":"https://doi.org/10.1136/acupmed-2013-010440","url":null,"abstract":"<p><strong>Objectives: </strong>To clarify changes in the cardiovascular autonomic nervous system function due to trigger point acupuncture, we evaluated differences in responses between acupuncture at trigger points and those at other sites using spectral analysis of heart rate variability.</p><p><strong>Methods: </strong>Subjects were 35 healthy men. Before measurements began the subjects were assigned to a trigger point acupuncture or control group based on the presence/absence of referred pain on applying pressure to a taut band within the right tibialis anterior muscle. The measurements were conducted in a room with a temperature of 25°C, with subjects in a long sitting position after 10 min rest. Acupuncture needles were retained for 10 min at two sites on the right tibialis anterior muscle. ECG was performed simultaneously with measurements of blood pressure and the respiratory cycle. Based on the R-R interval on the ECG, frequency analysis was performed, low-frequency (LF) and high-frequency (HF) components were extracted and the ratio of LF to HF components (LF/HF) was evaluated.</p><p><strong>Results: </strong>The trigger point acupuncture group showed a transient decrease in heart rate and an increase in the HF component but no significant changes in LF/HF. In the control group, no significant changes were observed in heart rate, the HF component or LF/HF. There were no consistent changes in systolic or diastolic blood pressure in either group.</p><p><strong>Conclusions: </strong>These data suggest that acupuncture stimulation of trigger points of the tibialis anterior muscle transiently increases parasympathetic nerve activity.</p>","PeriodicalId":378725,"journal":{"name":"Acupuncture in medicine : journal of the British Medical Acupuncture Society","volume":" ","pages":"273-8"},"PeriodicalIF":2.5,"publicationDate":"2014-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/acupmed-2013-010440","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40294271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Peggy Bosch, Heike Staudte, Maurits van den Noort, Sabina Lim
{"title":"A case study on acupuncture in the treatment of schizophrenia.","authors":"Peggy Bosch, Heike Staudte, Maurits van den Noort, Sabina Lim","doi":"10.1136/acupmed-2014-010547","DOIUrl":"https://doi.org/10.1136/acupmed-2014-010547","url":null,"abstract":"<p><strong>Unlabelled: </strong>This report describes the use of acupuncture as an add on treatment for a patient with chronic schizophrenia. The 63-year-old woman suffered from persistent hallucinations and even physical pain as a result of the hallucination of a black bird that kept pecking her back. The patient received 12 weekly acupuncture treatments. A clinical diagnostic interview and psychological testing (on sleep quality, depression, and on positive and negative symptoms) were conducted before, immediately after and 3 months after the acupuncture treatment. The results of the diagnostic interview gave important insights into the treatment effects. The patient experienced improved daily functioning and noticed a change in hallucinations. Although the hallucinations still occurred, she felt less disturbed by them. Interestingly, pain decreased markedly. In addition, the results showed that the overall score of the positive and negative symptoms did not change immediately; however, a decrease in symptoms occurred 3 months after acupuncture treatment. Moreover, the patient described an immediate improvement in sleep; this was confirmed by a daytime sleepiness questionnaire. The patient was not able to complete a (longer) test on sleep quality beforehand but did so after the treatment period. Finally, a delayed improvement in the depression scale was found. Although larger clinical intervention studies on acupuncture and schizophrenia are needed, the results of this case study indicate that acupuncture may be beneficial as an add on treatment tool in patients with schizophrenia.</p><p><strong>Trial registration number: </strong>3132.</p>","PeriodicalId":378725,"journal":{"name":"Acupuncture in medicine : journal of the British Medical Acupuncture Society","volume":" ","pages":"286-9"},"PeriodicalIF":2.5,"publicationDate":"2014-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/acupmed-2014-010547","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40299104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Does acupuncture modulate anti-inflammation via haemorphin in obesity?","authors":"Chang Zheng Song, Qing Wei Wang, Chang Cheng Song","doi":"10.1136/acupmed-2014-010541","DOIUrl":"https://doi.org/10.1136/acupmed-2014-010541","url":null,"abstract":"Obesity is a worldwide epidemic and has become a public health priority for which there is a need for effective treatments. It is recognised as a condition of low-grade systemic inflammation.1 Acupuncture may be a cost-effective approach to the treatment of obesity.2 ,3 However, the question of how acupuncture mechanistically exerts beneficial effects on obesity remains unanswered.\u0000\u0000A recent report provides evidence of decreased serum haemorphin-7 in obese subjects.4 Haemorphin is a family of endogenous …","PeriodicalId":378725,"journal":{"name":"Acupuncture in medicine : journal of the British Medical Acupuncture Society","volume":" ","pages":"205-6"},"PeriodicalIF":2.5,"publicationDate":"2014-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/acupmed-2014-010541","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40286117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effects of electroacupuncture on bone mineral density, oestradiol level and osteoprotegerin ligand expression in ovariectomised rabbits.","authors":"Jing He, Lin Yang, Yuxi Qing, Chengqi He","doi":"10.1136/acupmed-2012-010271","DOIUrl":"https://doi.org/10.1136/acupmed-2012-010271","url":null,"abstract":"<p><strong>Objectives: </strong>To investigate the effects of electroacupuncture (EA) on the oestradiol level, bone mineral density and osteoprotegerin ligand (OPGL) expression, and to explore whether EA might be a complementary method to prevent and treat osteoporosis.</p><p><strong>Methods: </strong>A total of 21 New Zealand rabbits were randomly divided into three groups: a normal control (NC) group undergoing no surgery or EA; an ovariectomised (OVX) group, in which rabbits were ovariectomised but did not receive EA; an EA group, in which rabbits were ovariectomised and treated with EA. Acupuncture was applied at ST35, BL20 and BL23 points bilaterally. EA (10 Hz, 2 mA) was applied bilaterally at BL20 and BL23 for 30 min a day for 14 days. After 14 days, all animals were killed. OPGL expression level was determined by immunohistochemistry. Blood serum levels of oestradiol were measured by ELISA and bone mineral density was detected by dual-energy x-ray absorptiometry.</p><p><strong>Results: </strong>After ovariectomy, the bone mineral density and oestradiol level decreased significantly in the OVX group compared with the NC group (p=0.001), whereas the OPGL expression level increased. After EA, the bone mineral density and oestradiol level increased compared with the OVX group (p=0.049 and p=0.012, respectively). The OPGL level OPGL level in the EA group was lower than that in the OVX group (p=0.022).</p><p><strong>Conclusions: </strong>EA restored bone mineral density towards normal and was associated with increased plasma oestradiol level and reduced OPGL expression in an ovariectomised rabbit model of osteoporosis.</p>","PeriodicalId":378725,"journal":{"name":"Acupuncture in medicine : journal of the British Medical Acupuncture Society","volume":" ","pages":"37-42"},"PeriodicalIF":2.5,"publicationDate":"2014-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/acupmed-2012-010271","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40268177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jae-Heung Cho, Dong-Hyun Nam, Ki-Tack Kim, Jun-Hwan Lee
{"title":"Acupuncture with non-steroidal anti-inflammatory drugs (NSAIDs) versus acupuncture or NSAIDs alone for the treatment of chronic neck pain: an assessor-blinded randomised controlled pilot study.","authors":"Jae-Heung Cho, Dong-Hyun Nam, Ki-Tack Kim, Jun-Hwan Lee","doi":"10.1136/acupmed-2013-010410","DOIUrl":"https://doi.org/10.1136/acupmed-2013-010410","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the feasibility and sample size required for a full-scale randomised controlled trial of the effectiveness of acupuncture with non-steroidal anti-inflammatory drugs (NSAIDs) for chronic neck pain compared with acupuncture or NSAID treatment alone.</p><p><strong>Methods: </strong>A total of 45 patients with chronic neck pain participated in the study. For 3 weeks the acupuncture with NSAIDs treatment group took NSAIDs (zaltoprofen, 80 mg) daily while receiving acupuncture treatment three times a week. The acupuncture treatment group received treatment three times a week and the NSAID treatment group took NSAIDs daily. The primary outcomes were to determine the feasibility and to calculate the sample size. As secondary outcomes, pain intensity and pain-related symptoms for chronic neck pain were measured.</p><p><strong>Results: </strong>With regard to enrolment and dropout rates, 88.2% of patients consented to be recruited to the trial and 15.6% of participants were lost to follow-up. The sample size for a full-scale trial was estimated to be 120 patients. Although preliminary, there was a significant change in the visual analogue scale (VAS) for neck pain intensity between the baseline measurement and each point of assessment in all groups. However, there was no difference in VAS scores between the three groups.</p><p><strong>Conclusions: </strong>This pilot study has provided the feasibility and sample size for a full-scale trial of acupuncture with NSAIDs for chronic neck pain compared with acupuncture or NSAID treatment alone. Further research is needed to validate the effects of acupuncture with NSAIDs.</p>","PeriodicalId":378725,"journal":{"name":"Acupuncture in medicine : journal of the British Medical Acupuncture Society","volume":" ","pages":"17-23"},"PeriodicalIF":2.5,"publicationDate":"2014-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/acupmed-2013-010410","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40276287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Acupuncture treatment for hypertension: a case study.","authors":"Lili Zhang, Pengfei Shen, Shu Wang","doi":"10.1136/acupmed-2013-010407","DOIUrl":"https://doi.org/10.1136/acupmed-2013-010407","url":null,"abstract":"<p><p>This report describes the regular use of acupuncture treatments for a patient with hypertension who could not tolerate the side effects of the antihypertensive agents. The patient received 60 acupuncture treatments in the course of 12 weeks, during which time his overall wellbeing improved, his blood pressure reduced and the side effects of antihypertensive drugs were removed. Although acupuncture plus the drug appeared to have a substantial synergistic effect that was weakened when the drug was discontinued, acupuncture may still play a role in the management of hypertension, especially for patients who cannot tolerate the side effects of antihypertensive agents. </p>","PeriodicalId":378725,"journal":{"name":"Acupuncture in medicine : journal of the British Medical Acupuncture Society","volume":" ","pages":"73-6"},"PeriodicalIF":2.5,"publicationDate":"2014-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/acupmed-2013-010407","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40268176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical effectiveness of electroacupuncture in meralgia paraesthetica: a case series.","authors":"Rosemary E Alexander","doi":"10.1136/acupmed-2013-010395","DOIUrl":"https://doi.org/10.1136/acupmed-2013-010395","url":null,"abstract":"<p><strong>Background: </strong>Meralgia paraesthetica is a fairly common condition resulting from entrapment of the lateral femoral cutaneous nerve. I have found that acupuncture produces a rapid improvement, sometimes effecting a cure, after only one or two treatments. I therefore invited referrals in order to collect a case series.</p><p><strong>Methods: </strong>A series of 10 patients, which included two who had refused surgery, but excluded those with significant lumbar spine problems, were treated. Visual Analogue Scale pain scores and analgesic intake were recorded weekly, starting before treatment. Four patients were receiving high doses of analgesics and the average period of symptoms was 3-4 years. Acupuncture points used were BL25, GB30, GB34, GB31, GB32, Huatuojiaji and ah shi points of the buttock and thigh, up to a depth of 7.5 cm. Electroacupuncture was normally given from the second treatment.</p><p><strong>Results: </strong>Without exception, patients were specifically tender over GB31 before they started treatment. Most were also tender over the upper lumbar spine. An average of four to five sessions of acupuncture was given. The pain scores for all 10 patients improved by at least 50%, including that of a patient with a 20-year history. At follow-up (varying from 3 to 36 months), improvement was nearly 100%. Most patients were able to stop their analgesics.</p><p><strong>Conclusions: </strong>Meralgia paraesthetica appears to respond rapidly to electroacupuncture. A significant trigger point at GB31 was universally present, which may aid diagnosis, although the reason for this is unclear. Further controlled studies are justified.</p>","PeriodicalId":378725,"journal":{"name":"Acupuncture in medicine : journal of the British Medical Acupuncture Society","volume":" ","pages":"435-9"},"PeriodicalIF":2.5,"publicationDate":"2013-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/acupmed-2013-010395","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40261211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The effect of electroacupuncture on osteotomy gap healing in a rat fibula model.","authors":"Motohiro Inoue, Miwa Nakajima, Tatsuya Hojo, Megumi Itoi, Hiroshi Kitakoji","doi":"10.1136/acupmed-2012-010294","DOIUrl":"https://doi.org/10.1136/acupmed-2012-010294","url":null,"abstract":"<p><strong>Objective: </strong>To examine the effect of electroacupuncture (EA) on osteotomy gap healing in a rat fibula model.</p><p><strong>Methods: </strong>A total of 40 12-week-old male Wistar rats underwent unilateral open osteotomy of the fibula to create a 2 mm gap. The rats were randomly assigned to an EA group (n=20) and a control group (n=20). In the EA group, a cathodal electrode was connected to an acupuncture needle percutaneously at the surgery site, while another acupuncture needle inserted 15 mm proximal to the surgery site was used as an anodal electrode. EA was performed 5 days a week for 6 weeks. The control group received no treatment. Some rats were killed at 3 days and 1 week after surgery and the cut end of the distal part of the fibula was surgically removed and histologically assessed. Haematoxylin and eosin (H&E) staining was used to measure total cell count and immunohistochemical staining to assess the increase in the bone morphogenetic protein 2 (BMP-2)-positive cells. The healing process was also assessed weekly after surgery via x-ray examinations.</p><p><strong>Results: </strong>At each time point, total cell count showed a marked increase in the EA group (p<0.05), while BMP-2 expression showed a tendency to increase in the EA group. Radiological examination showed a marked reduction in the distance between the cut ends of the fibula in the EA group.</p><p><strong>Conclusions: </strong>There was a marked increase in cell count and expression of growth factor in the EA group. These results indicate direct current EA could be useful for promoting bone healing.</p>","PeriodicalId":378725,"journal":{"name":"Acupuncture in medicine : journal of the British Medical Acupuncture Society","volume":" ","pages":"222-7"},"PeriodicalIF":2.5,"publicationDate":"2013-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/acupmed-2012-010294","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40234363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Physiological changes associated with de qi during electroacupuncture to LI4 and LI11: a randomised, placebo-controlled trial.","authors":"David Tai Wai Yu, Alice Yee Men Jones","doi":"10.1136/acupmed-2012-010280","DOIUrl":"https://doi.org/10.1136/acupmed-2012-010280","url":null,"abstract":"<p><strong>Background: </strong>Studies on the relationship between de qi intensity and activity changes in the autonomic nervous system (ANS) are scarce. This study investigates the physiological responses associated with de qi. The relationship between de qi intensity and such responses was determined.</p><p><strong>Method: </strong>This was a single-blinded, randomised, placebo-controlled trial. A total of 36 subjects (19 men, 17 women), aged 34.5±4.6 years, were randomly assigned to group 1 (electroacupuncture at 2 Hz, 0.4 ms to right LI4 and LI11 for 30 min), group 2 (electroacupuncture stimulation to bilateral patellae) or group 3 (sham electroacupuncture to right LI4 and LI11 but over Duoderm pads). Heart rate (HR), mean arterial blood pressure (MAP) and HR variability by low/high frequency (LF/HF) were recorded 5 min before, during and 5 min after the intervention. Needle sensations were quantified by the Modified Massachusetts General Hospital Acupuncture Sensation Scale - Chinese version (C-MMASS) and the C-MMASS index was computed.</p><p><strong>Results: </strong>A significant increase in LF/HF, MAP and HR was observed in group 1. A small and significant increase in LF/HF was observed in group 2 but the changes in MAP and HR in groups 2 and 3 were not significant. The C-MMASS index was highest in group 1 (5.3±1.3), moderate in group 2 (3.5±0.7) and lowest in group 3 (0.77±0.2). A positive correlation between de qi intensity and changes in LF/HF, MAP and HR was observed.</p><p><strong>Conclusions: </strong>This study suggests that de qi is associated with physiological changes, and that de qi intensity increases with an increase in sympathetic discharge of the ANS.</p>","PeriodicalId":378725,"journal":{"name":"Acupuncture in medicine : journal of the British Medical Acupuncture Society","volume":" ","pages":"143-50"},"PeriodicalIF":2.5,"publicationDate":"2013-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/acupmed-2012-010280","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40236049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Saeed Shoar, Sara Esmaeili, Zhamak Khorgami, Mohammad Naderan, Nasrin Shoar
{"title":"Efficacy of acupuncture in prevention of postoperative anaesthesia-related shivering.","authors":"Saeed Shoar, Sara Esmaeili, Zhamak Khorgami, Mohammad Naderan, Nasrin Shoar","doi":"10.1136/acupmed-2012-010250","DOIUrl":"https://doi.org/10.1136/acupmed-2012-010250","url":null,"abstract":"Dear editor\u0000\u0000Postoperative shivering still occurs as a complication of general anaesthesia.1 ,2 Shivering depends on age, sex, duration of anaesthesia and type of anaesthetic agent(s).1–3 Primarily due to anaesthetic agents such as isoflurane, this type of shivering presents as spontaneous muscular activity in patients with normal body temperature after general anaesthesia for specific operations.4 ,5 With advances in alternative medicine in recent decades, acupuncture is increasingly known as an effective method in managing complications of surgery and anaesthesia. However, the most efficacious point of stimulation still needs investigation.\u0000\u0000A prospective non-randomised clinical study was performed on 228 patients admitted to the department of surgery at Shariati Hospital between March 2011 and June 2011. The Research Ethics …","PeriodicalId":378725,"journal":{"name":"Acupuncture in medicine : journal of the British Medical Acupuncture Society","volume":" ","pages":"120-1"},"PeriodicalIF":2.5,"publicationDate":"2013-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/acupmed-2012-010250","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40213873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}