The Pan-American Journal of Ophthalmology最新文献_第3页

The prevalence of diabetes among male glaucoma patients 男性青光眼患者糖尿病患病率分析

The Pan-American Journal of Ophthalmology Pub Date : 2020-01-01 DOI: 10.4103/pajo.pajo_31_20

N. Antonova, I. Dersu, E. Burstein, Lance J. Lyons, W. Hou

{"title":"The prevalence of diabetes among male glaucoma patients","authors":"N. Antonova, I. Dersu, E. Burstein, Lance J. Lyons, W. Hou","doi":"10.4103/pajo.pajo_31_20","DOIUrl":"https://doi.org/10.4103/pajo.pajo_31_20","url":null,"abstract":"Introduction: The purpose of this study was to examine the relationship between diabetes and glaucoma. Methods: Consecutive 143 subjects with primary angle-closure glaucoma and 127 subjects with primary open-angle glaucoma (control) were studied retrospectively at an urban Veterans Administration Hospital. In addition to ocular examination findings, body mass index (BMI) and diabetes mellitus (DM) status were recorded. Results: All subjects in this study were male. The mean age was 72.3 years old in primary open angle versus 71.1 in primary angle-closure subjects. Half of the subjects with angle closure and 70% of open-angle subjects were self-identified as African–American. BMI was not significantly different between the two groups (28.2 in open angle vs. 28.7 in angle closure; P = 0.45). The percentage of DM was higher in subjects with primary angle closure than in those with primary open-angle glaucoma (43% vs. 29%, P = 0.001; Chi-square test). The odds of having DM were nearly two times higher in angle-closure subjects than open-angle subjects (Logistic regression, P = 0.01, 95% confidence interval: 1.17–3.30). Conclusion: In this retrospective study, diabetes was found to be associated with higher risk for primary angle-closure glaucoma.","PeriodicalId":378703,"journal":{"name":"The Pan-American Journal of Ophthalmology","volume":"75 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133213528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pattern scanning laser trabeculoplasty versus selective laser trabeculoplasty in patients with primary open angle glaucoma 模式扫描激光小梁成形术对比选择性激光小梁成形术治疗原发性开角型青光眼

The Pan-American Journal of Ophthalmology Pub Date : 2020-01-01 DOI: 10.4103/pajo.pajo_16_20

Sandra Rey, M. Perez, M. Aguilar, Hernán Ríos Calixto, Shirley Colón, Héctor D. Forero

{"title":"Pattern scanning laser trabeculoplasty versus selective laser trabeculoplasty in patients with primary open angle glaucoma","authors":"Sandra Rey, M. Perez, M. Aguilar, Hernán Ríos Calixto, Shirley Colón, Héctor D. Forero","doi":"10.4103/pajo.pajo_16_20","DOIUrl":"https://doi.org/10.4103/pajo.pajo_16_20","url":null,"abstract":"Purpose: The aim of this study is to compare the reduction percent of intraocular pressure (IOP) after selective laser trabeculoplasty (SLT) or pattern laser scanning trabeculoplasty (PSLT) in a group of patients with hypertensive glaucoma. Materials and Methods: A quasi-experimental prospective study of the patients with baseline IOP of 20 mmHg or more (with at least 1 IOP lowering medication) underwent either PSLT or SLT at 360°. IOP was measured in the following time points: Hour 1, Day 1 and 7, months 1, 3, 6, and 12 after the laser procedure. Results: The mean age was 68.1 ± 10.1 in the PSLT group and 71.8 ± 4.0 in the SLT group. Eleven eyes (8 patients) underwent PSLT and 9 eyes (6 patients) underwent SLT. Baseline IOP was 22.45 ± 2.4 mmHg, PSLT; 25.0 ± 2.2 mmHg, SLT; (P > 0.05) on an average of 2.4 medications. In the PSLT group, the mean IOP at 1 h, 1, 3, 6 and 12 months was 19.0 ± 5.0, 14.7 ± 2.4, 15.3 ± 3.0, 14.5 ± 2.7, and 13.0 ± 3.1, respectively. In the SLT group, the mean IOP at 1 h, 1, 3, 6 and 12 months was 25.6 ± 6.4, 15.9 ± 4.4, 15.3 ± 2.6, 16.7 ± 4.8, and 21.2 ± 4.3, respectively. IOP was significantly lower in the PSLT group compared to the SLT group at 1 h (P < 0.01) and 12 months (P < 0.01). No serious adverse events were recorded. Conclusions: PSLT was similar in effect compared to SLT at 1, 3, 6 months, and more effective than SLT at 12 months.","PeriodicalId":378703,"journal":{"name":"The Pan-American Journal of Ophthalmology","volume":"75 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134185750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Expression of BRCA1-associated protein 1 in primary tumors and metastasis in an animal model of uveal melanoma 葡萄膜黑色素瘤动物模型中brca1相关蛋白1在原发肿瘤和转移中的表达

The Pan-American Journal of Ophthalmology Pub Date : 2020-01-01 DOI: 10.4103/pajo.pajo_29_20

C. Castro, J. Burnier, Sabrina Bergeron, J. Coblentz, A. Dias, M. Burnier

{"title":"Expression of BRCA1-associated protein 1 in primary tumors and metastasis in an animal model of uveal melanoma","authors":"C. Castro, J. Burnier, Sabrina Bergeron, J. Coblentz, A. Dias, M. Burnier","doi":"10.4103/pajo.pajo_29_20","DOIUrl":"https://doi.org/10.4103/pajo.pajo_29_20","url":null,"abstract":"Background: Uveal melanoma (UM) is the most common primary intraocular tumor in adults. Despite successful local treatment, approximately 50% of these patients develop lethal metastatic disease. BRCA1-associated protein 1 (BAP1) encodes BAP1, which functions as a tumor suppressor. Inactivation by a somatic mutation in BAP1 results in a loss of protein expression, which is associated with increased risk of metastasis. Aim: To analyze the expression of BAP1 protein in primary uveal tumors and their corresponding metastasis in an animal model of UM and to determine whether BAP1 expression is lost during the metastatic process. Subjects and Methods: Postmortem eyes and lungs with metastasis from nine rabbits previously inoculated with human UM cells expressing BAP1 (92.1 strain) were analyzed. Immunohistochemistry was performed on formalin-fixed paraffin-embedded samples using a monoclonal BAP1 (C-4) antibody. Expression was evaluated by the extent and intensity of staining. All primary tumors and metastasis were positive for BAP1. Results: The staining was diffuse and intense in the primary tumors of four rabbits (67%), focal-intense in one rabbit and focal-mild in one rabbit. All lung metastasis showed focal staining. All animals with intense BAP1 staining in the primary tumor showed mild BAP1 in the metastasis. Discussion: A predominant pattern observed between primary and metastatic lesion shows a transition from moderate into mild intensity and diffuse into the focal extent, suggesting a decrease in BAP1 expression. Future studies, including the human tissue of primary UM and their corresponding metastasis, should be performed to corroborate these findings.","PeriodicalId":378703,"journal":{"name":"The Pan-American Journal of Ophthalmology","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121919937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Autologous fascia lata grafting in scleromalacia perforans 自体阔筋膜移植术治疗穿孔硬化症

The Pan-American Journal of Ophthalmology Pub Date : 2020-01-01 DOI: 10.4103/pajo.pajo_30_20

Karin A. Caro, Luz C. Chávez, Carla Sanchez, Eduardo Archila

引用次数: 0

Histopathological analysis of juvenile patients with melanocytic lesions of the conjunctiva 青少年结膜黑素细胞病变的组织病理学分析

The Pan-American Journal of Ophthalmology Pub Date : 2017-06-23 DOI: 10.4103/pajo.pajo_35_22

G. Barros, Marcela Barros, D. Sousa, L. Bongiovanni, Gabriela Naomi, M. Burnier

引用次数: 0

A case of bilateral macular hole in a young HIV-positive patient 年轻hiv阳性患者双侧黄斑裂孔1例

The Pan-American Journal of Ophthalmology Pub Date : 1900-01-01 DOI: 10.4103/PAJO.PAJO_15_19

J. Shifa, Alemayehu Mekonnen Gezmu, G. Ayane, M. Kassa

引用次数: 0

Bilateral ocular decompression retinopathy after trabeculectomy in steroid-induced glaucoma 类固醇性青光眼小梁切除术后双侧眼减压视网膜病变

The Pan-American Journal of Ophthalmology Pub Date : 1900-01-01 DOI: 10.4103/pajo.pajo_4_23

T. Gil-Martínez, OlgaRebeca Cedeño

引用次数: 0

Spontaneous expulsive suprachoroidal hemorrhage 自发性排出性脉络膜上出血

The Pan-American Journal of Ophthalmology Pub Date : 1900-01-01 DOI: 10.4103/pajo.pajo_11_20

H. Ferreira, B. Patrús, G. Neves, Pedro Filipe, C. Sawatani, Marcelo Sobrinho

引用次数: 0

Tubulointerstitial nephritis with uveitis in a young male patient 小管间质性肾炎合并葡萄膜炎1例

The Pan-American Journal of Ophthalmology Pub Date : 1900-01-01 DOI: 10.4103/pajo.pajo_34_23

JuanJose Castro-Barandica, D. Esmeral-Ordoñez, Karol Quintero-Lizcano, C. Rangel

引用次数: 0

Implementation of teaching strategies and innovation to comply with the training competencies in an ophthalmology residency program during the coronavirus disease-19 pandemic 新冠肺炎大流行期间眼科住院医师培训能力教学策略的实施与创新

The Pan-American Journal of Ophthalmology Pub Date : 1900-01-01 DOI: 10.4103/pajo.pajo_124_21

A. Rodríguez-Garcia, AngelEduardo Gonzalez-Garcia, Y. Macías-Rodríguez, R. Ruiz-Lozano

引用次数: 0