Respiratory Science最新文献_第6页

Osteoporosis Prevalence In Stable Patients With Chronic Obstructive Pulmonary Disease 慢性阻塞性肺疾病稳定期患者骨质疏松患病率

Respiratory Science Pub Date : 2021-02-27 DOI: 10.36497/RESPIRSCI.V1I2.19

Dwi Handoko, F. Yunus, Budhi Antariksa, Rochsismandoko

{"title":"Osteoporosis Prevalence In Stable Patients With Chronic Obstructive Pulmonary Disease","authors":"Dwi Handoko, F. Yunus, Budhi Antariksa, Rochsismandoko","doi":"10.36497/RESPIRSCI.V1I2.19","DOIUrl":"https://doi.org/10.36497/RESPIRSCI.V1I2.19","url":null,"abstract":"Background: Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality in the world. Comorbid diseases in COPD contributing to low health status, affecting the duration of treatment and even death. Osteoporosis is a quite often comorbid that found in COPD. In Indonesia, there are no data of prevalence on osteoporosis in patient with stable COPD. The aim this research to get the data of osteoporosis in patients with stable COPD at Persahabatan Hospital. \u0000Method: The studie’s design was cross-sectional. Patients with stable COPD who came to the Asthma/COPD policlinic at Persahabatan Hospital who meet the criteria of inclusion and exclusion. Subjects had an examined of bone mineral density using dual energy x-ray absorptiometry (DXA) and had an examined of vitamin D blood level. At the time of visit, conducted anamnesis of symptoms, exacerbations, history of smoking, used of corticosteroid (oral or inhaled), comorbid, assessment of nutritional status. \u0000Results: Subjects were dominated with male (90.6%) in the age group 65-75 years old (53.1%), and smoking history (84.4%). The most degree of COPD were GOLD II (46.9%) and group B (50%) that using corticosteroid (65.7%). Prevalence of osteoporosis was 37.5%. There were no statistically significant between COPD group, the degree of COPD, sex, smoking history, history of corticosteroid, age, levels of 25-OHD, pulmonary function with the occurrence of osteoporosis in patients with stable COPD. There were a statistically significant on low BMI as a risk factor for osteoporosis in stable COPD. \u0000Conclusion: The prevalence of osteoporosis in patients with stable COPD in the Persahabatan Hospital is 37.5%. There are a statistically significant relationship between BMI with osteoporosis in patients with stable COPD.","PeriodicalId":377868,"journal":{"name":"Respiratory Science","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116727437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Concordance Rate Between Examination of EGFR Mutation Blood Plasma Sample (ctDNA) With Citological/Histopathological Sample in Adenocarcinoma Lung Cancer 腺癌肺癌EGFR突变血浆样本(ctDNA)检测与病理学/组织学样本的符合率

Respiratory Science Pub Date : 2020-10-31 DOI: 10.36497/RESPIRSCI.V1I1.9

Dian Utami Wulaningrum, A. Setijadi, Suradi

{"title":"Concordance Rate Between Examination of EGFR Mutation Blood Plasma Sample (ctDNA) With Citological/Histopathological Sample in Adenocarcinoma Lung Cancer","authors":"Dian Utami Wulaningrum, A. Setijadi, Suradi","doi":"10.36497/RESPIRSCI.V1I1.9","DOIUrl":"https://doi.org/10.36497/RESPIRSCI.V1I1.9","url":null,"abstract":"Background: Most adenocarcinoma lung cancer which is found at an advanced stage with cytology / histopathological samples is hardly available. Examination of EGFR mutations in ctDNA blood plasma sampling is simpler and easier, which also can be used as predictive and prognostic markers in non-small cell carcinoma lung cancer patients. The purpose of this study is to determine and analyse the degree of compatibility between examination of EGFR mutations by blood plasma (ctDNA) samples with the examination of cytology / histopathological EGFR mutations in adenocarcinoma lung cancer. \u0000Methods: Diagnostic test research, by taking medical records of patients with adenocarcinoma lung cancer from January to September 2019 at Dr. Moewardi Surakarta, who was examined by EGFR mutations in cytology / histopathology and ctDNA samples. \u0000Result: The Subjects of this study were 73 patients with adenocarcinoma lung cancer. The level of compatibility of ctDNA with EGFR mutations in cytology / histopathology samples was categorized as moderate and statistically significant (Kappa = 0.459; p = 0.000). \u0000Conclusion: The level of concordance between the examination of EGFR mutations with blood plasma samples (ctDNA) with the examination of EGFR mutations in cytology / histopathology samples was moderate and statistically significant.","PeriodicalId":377868,"journal":{"name":"Respiratory Science","volume":"58 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122631659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Two-years Biannual Evaluation of Drug-resistant Tuberculosis Patients Completing Their Treatment at Persahabatan General Hospital Jakarta 雅加达Persahabatan总医院完成治疗的耐药结核病患者两年半年评估

Respiratory Science Pub Date : 2020-10-31 DOI: 10.36497/respirsci.v1i1.4

M. Murniati, D. Handayani, F. Isbaniah

{"title":"Two-years Biannual Evaluation of Drug-resistant Tuberculosis Patients Completing Their Treatment at Persahabatan General Hospital Jakarta","authors":"M. Murniati, D. Handayani, F. Isbaniah","doi":"10.36497/respirsci.v1i1.4","DOIUrl":"https://doi.org/10.36497/respirsci.v1i1.4","url":null,"abstract":"Background: Drug-resistant tuberculosis (DR-TB) is a worldwide threat, including in Indonesia, which course of treatments are time consuming and are expensive. Recent findings suggest trends in recurrence of DR-TB, while no data is available to summarize the recurrence of DR-TB in Indonesia. \u0000Objective: This study aimed to evaluate DR-TB patients which was biannually performed for two-years (e.g. at the 6th, 12th, 18th, and 24th mos) after treatment completion. \u0000Methods: This cross-sectional study involved DR-TB patients completing their treatment at Persahabatan General Hospital Jakarta, Indonesia, between April and December 2017. The post-treatment evaluation during the 6th, 12th, 18th, and 24th mos included clinical, chest x-ray (CXR) and sputum culture examination. \u0000Results: Sixty patients were observed in this study, 31 (51.7%) were males and 29 (48.3%) were females. The mean age was 42.3+12.5 yo and the mean body mass index was 21.75+4.34. Fourty nine (81.7%) patients showed extensive lesions per CXR and none of the patient showed Mycobacterium tuberculosis growth per sputum culture. \u0000Conclusion: There was no recurrence of DR-TB from patients completing their treatment at Persahabatan General Hospital Jakarta, Indonesia during two-years post-treatment evaluation.","PeriodicalId":377868,"journal":{"name":"Respiratory Science","volume":"65 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116546201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Lung Function and Respiratory Symptoms of Petrol Station Attendants in Central and North Jakarta and Its Contributing Factors 雅加达中部和北部加油站服务员的肺功能和呼吸道症状及其影响因素

Respiratory Science Pub Date : 2020-10-31 DOI: 10.36497/RESPIRSCI.V1I1.7

P. Ramadhany, F. Yunus, A. Susanto

{"title":"Lung Function and Respiratory Symptoms of Petrol Station Attendants in Central and North Jakarta and Its Contributing Factors","authors":"P. Ramadhany, F. Yunus, A. Susanto","doi":"10.36497/RESPIRSCI.V1I1.7","DOIUrl":"https://doi.org/10.36497/RESPIRSCI.V1I1.7","url":null,"abstract":"Background: To satisfy growing needs of petrol consumption in big city many new petrol stations has been built. Petrol station attendant is considered to have high risk exposure to dangerous pollutant from motor vehicle emission and petrol fumes, especially while filling up petrol tanks. Combination of those exhaust and petrol fumes is suspected to cause the reduction of lung function. \u0000Methods: This research is a cross sectional study in petrol station in Central Jakarta and North Jakarta region between August 2017 and February 2018. A total of 97 petrol station attendants were taken in this research using consecutive sampling technique. The subjects were interviewed with questionnaires, spirometry and chest radiograph. Measurements of sulfur dioxide (SO2), nitrogen dioxide (NO2), carbon monoxide (CO), ozone (O3), particulate matter 2,5 (PM 2,5) and steam gasoline (benzene) concentrations were performed at the study sites. \u0000Results: In this study, 56.7% normal spirometry results, 42.3% abnormalities in the form of restriction, 1% obstruction and none of which experienced mixed disorders of restriction and obstruction. Most subjects (84.6%) did not experience respiratory complaints, 10.3% had a dry cough and 5.1% complained of cough with phlegm. There was a statistically significant association between peak expiratory flow and duration of work (p=0.011), but no significant association with other parameters such as forced vital capacity (FVC), %FVC, forced expiratory volume in the first second (FEV1), %FEV1 and the ratio of FEV1/FVC. \u0000Conclusion: Prevalence of lung function abnormalities of petrol station attendant is 43,3% and respiratory symptoms at 15,4% subject.","PeriodicalId":377868,"journal":{"name":"Respiratory Science","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130919553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1