Journal of Organometallic Chemistry最新文献_第9页

Hydrosilylation or dehydrogenative silylation pathways via the Au-catalyzed activation of hydrosilanes

IF 2.1 3区化学

Journal of Organometallic Chemistry Pub Date : 2025-01-28 DOI: 10.1016/j.jorganchem.2025.123546

Maria Ioanna Karapanou , Marios Kidonakis , Dimitra Malliotaki , Elisavet-Maria Zantioti-Chatzouda , Manolis Stratakis

引用次数: 0

Thienylquinoline-based ionic Iridium(III) complexes as highly efficient Sonosensitizers for Sonodynamic therapy

IF 2.1 3区化学

Journal of Organometallic Chemistry Pub Date : 2025-01-28 DOI: 10.1016/j.jorganchem.2025.123547

Zhuang Lv , Pei Zhang , Ke Hua , Jiayang Jiang

{"title":"Thienylquinoline-based ionic Iridium(III) complexes as highly efficient Sonosensitizers for Sonodynamic therapy","authors":"Zhuang Lv , Pei Zhang , Ke Hua , Jiayang Jiang","doi":"10.1016/j.jorganchem.2025.123547","DOIUrl":"10.1016/j.jorganchem.2025.123547","url":null,"abstract":"<div><div>Sonodynamic therapy (SDT) is an emerging cancer therapeutic method whose mechanism is very similar to that of photodynamic therapy (PDT), with the primary difference being that its excitation source is ultrasound. Hence, SDT has significantly a greater penetration depth, making it more suitable for treating deep-seated tumors. Sonosensitizers, as a key component of SDT, can be excited by ultrasound and generate reactive oxygen species (ROS). In this work, two novel ionic iridium(III) complexes (Ir1 and Ir2) bearing a 4-methyl-2-(thiophen-2-yl)quinolone cyclometalating ligand are synthesized, and their photophysical properties, sono-chemical properties and <em>in vitro</em> SDT are studied. Ir1 and Ir2 have long excited-state lifetimes and exhibit good stability under ultrasound and at different pH values. These two iridium(III) complexes can generate singlet oxygen under ultrasound both in solution and in cells. They show good biocompatibility in the absence of ultrasound and high toxicity in the presence of ultrasound, indicating their great potential for sonodynamic therapy applications.</div></div>","PeriodicalId":374,"journal":{"name":"Journal of Organometallic Chemistry","volume":"1029 ","pages":"Article 123547"},"PeriodicalIF":2.1,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143268004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Long-chain PdIICoII paddle wheel carboxylate complexes: Synthesis, thermal analysis and electrochemistry

IF 2.1 3区化学

Journal of Organometallic Chemistry Pub Date : 2025-01-28 DOI: 10.1016/j.jorganchem.2025.123548

Ebrahiem Botha , Alice Brink , Elizabeth Erasmus

{"title":"Long-chain PdIICoII paddle wheel carboxylate complexes: Synthesis, thermal analysis and electrochemistry","authors":"Ebrahiem Botha , Alice Brink , Elizabeth Erasmus","doi":"10.1016/j.jorganchem.2025.123548","DOIUrl":"10.1016/j.jorganchem.2025.123548","url":null,"abstract":"<div><div>Mixed-metal carboxylate complexes were synthesized by reacting one equivalent of [Pd<sub>3</sub><sup>II</sup>(μ-OOC(CH<sub>2</sub>)<sub>n</sub>CH<sub>3</sub>)<sub>6</sub>] with three equivalents of [Co<sup>II</sup>(OOC(CH<sub>2</sub>)<sub>n</sub>CH<sub>3</sub>)<sub>2</sub>] where <em>n</em> = 4, 6, 8, or 10. This reaction resulted in the formation of [Pd<sup>II</sup>Co<sup>II</sup>(µ-OOC(CH<sub>2</sub>)<sub>n</sub>CH<sub>3</sub>)<sub>4</sub>] where <em>n</em> = 4, 6, 8, or 10. Characterisation via ATR-FTIR revealed that mixed-metal complexes exhibit multiple coordination modes, including unidentate, bidentate, tridendate, and bridging (<em>syn-syn</em>) binding modes. The single crystal X-ray structure of [Pd<sup>II</sup>Co<sup>II</sup>(μ-OOC(CH<sub>2</sub>)<sub>8</sub>CH<sub>3</sub>)<sub>4</sub>] (<em>Z</em> = 2, space group <em>P</em>2<sub>1</sub>/<em>c</em>) confirmed the binding modes observed in the ATR-FTIR studies.</div><div>Cyclic Voltammetry of [Pd<sub>3</sub><sup>II</sup>(μ-OOC(CH<sub>2</sub>)<sub>n</sub>CH<sub>3</sub>)<sub>6</sub>] and [Pd<sup>II</sup>Co<sup>II</sup>(µ-OOC(CH<sub>2</sub>)<sub>n</sub>CH<sub>3</sub>)<sub>4</sub>] where <em>n</em> = 4, 6, 8, or 10 demonstrated that the redox process for Pd<sup>0</sup> → Pd<sup>II</sup> were both chemically and electrochemically irreversible. Furthermore, [Pd<sup>II</sup>Co<sup>II</sup>(µ-OOC(CH<sub>2</sub>)<sub>n</sub>CH<sub>3</sub>)<sub>4</sub>] did not exhibit an oxidation wave. Additionally, a progressive decrease in negative reduction of the Pd was observed with increasing carbon chain length.</div><div>TGA-MS analysis identified volatile decomposition products such as methane, hydroxide ions, water, carbon monoxide, oxygen, methanol, propyne, carbon dioxide and other species. The non-volatile decomposition residues consisted of metal oxides.</div></div>","PeriodicalId":374,"journal":{"name":"Journal of Organometallic Chemistry","volume":"1029 ","pages":"Article 123548"},"PeriodicalIF":2.1,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143267980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Supported silver nanoparticles over starch-modified magnetic nanoparticles: Characterization, Its application for A3 coupling reactions, analgesic and anesthetic activities

IF 2.1 3区化学

Journal of Organometallic Chemistry Pub Date : 2025-01-27 DOI: 10.1016/j.jorganchem.2025.123544

Junwei Lu , Meilan Zhang , Attalla F. El-kott , Mohammed A. AlShehri , Sally Negm , Ali S. AlSheri

{"title":"Supported silver nanoparticles over starch-modified magnetic nanoparticles: Characterization, Its application for A3 coupling reactions, analgesic and anesthetic activities","authors":"Junwei Lu , Meilan Zhang , Attalla F. El-kott , Mohammed A. AlShehri , Sally Negm , Ali S. AlSheri","doi":"10.1016/j.jorganchem.2025.123544","DOIUrl":"10.1016/j.jorganchem.2025.123544","url":null,"abstract":"<div><div>This study focuses on the synthesis and characterization of silver nanoparticles (Ag NPs) supported on starch-coated magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles (Fe<sub>3</sub>O<sub>4</sub>-starch/Ag NPs) using a green approach, which avoids the use of any harmful or toxic reducing agents and stabilizers. The structural and textural properties of the nanocomposite were thoroughly examined using various physicochemical techniques, including TEM, FE-SEM, EDX, VSM, XRD and ICP-OES. The potential of Fe<sub>3</sub>O<sub>4</sub>-starch/Ag NPs as a catalyst in the aldehyde-alkyne-amine (A<sup>3</sup>) coupling reaction for the synthesis of propargylamine derivatives was also explored. This catalytic system offers significant benefits such as high catalytic efficiency, simplicity, environmental sustainability, and excellent reaction yields. The local anesthetic effects were assessed in models of frogs and guinea pigs, revealing noteworthy efficacy in both animal species. The analgesic effects were evaluated in mice by administering various doses orally. Writhing episodes caused by acetic acid were notably decreased in a manner that depended on the dosage. Furthermore, an assessment was conducted to determine the anti-inflammatory effects of the identical dosage. After being administered orally, the inflammation in the paws of mice induced by carrageenin, a commonly used inflammatory agent, was noticeably reduced. The Fe<sub>3</sub>O<sub>4</sub>-starch/Ag NPs nanocomposite shows promise as a groundbreaking therapeutic medication in the future, demonstrating analgesic, anti-inflammatory effects, and local anesthetic qualities.</div></div>","PeriodicalId":374,"journal":{"name":"Journal of Organometallic Chemistry","volume":"1029 ","pages":"Article 123544"},"PeriodicalIF":2.1,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143388050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Structural investigation and application of ruthenium(II)-benzimidazole complexes for N-alkylation

IF 2.1 3区化学

Journal of Organometallic Chemistry Pub Date : 2025-01-25 DOI: 10.1016/j.jorganchem.2025.123530

Funda Doğan Karabekmez , Emine Özge Karaca , Nevin Gürbüz , Namık Özdemir , İsmail Özdemir

{"title":"Structural investigation and application of ruthenium(II)-benzimidazole complexes for N-alkylation","authors":"Funda Doğan Karabekmez , Emine Özge Karaca , Nevin Gürbüz , Namık Özdemir , İsmail Özdemir","doi":"10.1016/j.jorganchem.2025.123530","DOIUrl":"10.1016/j.jorganchem.2025.123530","url":null,"abstract":"<div><div>The <em>N</em>-substituted ligands (<strong>1a</strong>-<strong>d</strong>) were synthesized through the reaction of benzimidazole and a base with alkyl halides. After that, a new series of <em>N</em>-coordinated benzimidazole ruthenium(II) complexes (<strong>2a-d</strong>) was synthesized in this study. <sup>1</sup>H and <sup>13</sup>C NMR spectroscopy, elemental analysis and FT-IR spectroscopy methods were applied to examine the structures of the complexes. The structures of complexes <strong>2a</strong>-<strong>c</strong> were additionally elucidated by X-ray diffraction spectroscopy. Arylmethyl alcohols have been alkylated with these complexes in the presence of KO<em><sup>t</sup></em>Bu under solvent-free mild conditions at 120 °C. These complexes catalyzed the N-alkylation process, yielding secondary amines from primary amines with great selectivity. Without using solvents, these complexes are found to be effective catalysts for the alkylation of aromatic amines with various alcohols. Given the structural similarity of the ruthenium complexes, it is clear that there is no substantial difference in their catalytic activity; however, the selectivity of the reaction is dependent upon the characteristics of the amines and alcohols involved.</div></div>","PeriodicalId":374,"journal":{"name":"Journal of Organometallic Chemistry","volume":"1028 ","pages":"Article 123530"},"PeriodicalIF":2.1,"publicationDate":"2025-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143322263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Overview of organometallic electrochemistry

IF 2.1 3区化学

Journal of Organometallic Chemistry Pub Date : 2025-01-23 DOI: 10.1016/j.jorganchem.2025.123539

Kimia Zarean Mousaabadi , Hassan Hadadzadeh

引用次数: 0

Probing the fascinating role of Eu-AgNPs in the synthesis of bioactive substituted chalcones as a green matrix and study of their biological potential

IF 2.1 3区化学

Journal of Organometallic Chemistry Pub Date : 2025-01-22 DOI: 10.1016/j.jorganchem.2025.123528

Preeti Singh , Preeti Yadav , Shashi Bala , Jaishri Kaur

{"title":"Probing the fascinating role of Eu-AgNPs in the synthesis of bioactive substituted chalcones as a green matrix and study of their biological potential","authors":"Preeti Singh , Preeti Yadav , Shashi Bala , Jaishri Kaur","doi":"10.1016/j.jorganchem.2025.123528","DOIUrl":"10.1016/j.jorganchem.2025.123528","url":null,"abstract":"<div><div>The demand of environment benign and biologically active nanomaterials has spurred the development of green synthesis methodologies. The aim of present study was to develop a cost effective and ecofriendly synthesis methodology for Eucalyptus decorated silver nanoparticles (Eu-AgNPs) using a sustainable approach and affirmed by range of physicochemical techniques including fourier-transform infrared (FT-IR) spectroscopy, scanning electron microscopy (SEM), energy – dispersive x-ray (EDX) spectroscopy, transmission electron microscopy (TEM), thermogravemetric analysis (TGA), and powder x-ray diffraction (PXRD).The synthesized Eu-AgNPs were utilized as a potential catalyst in the synthesis of substituted chalcones. The robust features of the present approach exhibit remarkable catalytic performance, easy work up procedures, broad functional group tolerance, recyclability of the catalyst, better green chemistry metrices like low E factor (0.15), low PMI (1.15), high RME (86.53 %), high AE (94.0 %), high CE (92.0 %), high TON (47.84) and high TOF (191.36 h<sup>-1</sup>). Furthermore, to evaluate the antimicrobial activity of prepared Eu-AgNPs, experiments were conducted using nutrient agar medium (NAM) utilizing diffusion zone method. This study demonstrated the dual utility of Eu-AgNPs as a potential and sustainable catalyst for synthesis of high value chemicals and as effective antimicrobial agents, which contributes to the advancement of green chemistry and nanotechnology.</div></div>","PeriodicalId":374,"journal":{"name":"Journal of Organometallic Chemistry","volume":"1028 ","pages":"Article 123528"},"PeriodicalIF":2.1,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143322265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Regioselective domino C–C/C–O arylation of 1,2,3-triiodobenzenes and 1,3-diketones: Synthesis and in silico evaluation of 7-iodobenzo[b]furan as potential ALK inhibitors

IF 2.1 3区化学

Journal of Organometallic Chemistry Pub Date : 2025-01-21 DOI: 10.1016/j.jorganchem.2025.123526

Raed M. Al-Zoubi , Walid K. Al-Jammal , Mohanad Shkoor , Abdulilah D. Bani-Yaseen , Abbas Khan , Abdelali Agouni , Robert McDonald

{"title":"Regioselective domino C–C/C–O arylation of 1,2,3-triiodobenzenes and 1,3-diketones: Synthesis and in silico evaluation of 7-iodobenzo[b]furan as potential ALK inhibitors","authors":"Raed M. Al-Zoubi , Walid K. Al-Jammal , Mohanad Shkoor , Abdulilah D. Bani-Yaseen , Abbas Khan , Abdelali Agouni , Robert McDonald","doi":"10.1016/j.jorganchem.2025.123526","DOIUrl":"10.1016/j.jorganchem.2025.123526","url":null,"abstract":"<div><div>We report a simple, direct, and regioselective protocol for the synthesis of 2,3-disubstituted 7-iodobenzo[b]furans via domino double C<img>C/C<img>O arylations of 1,2,3-triiodobenzene and 1,3-dicarbonyl compounds. Remarkably, the C-arylation occurred exclusively at the terminal positions, which are the most reactive and least sterically hindered. The O-arylation reactions were selectively performed with the more reactive carbonyl group. This domino process demonstrated excellent substrate tolerance. Under optimized conditions, the reaction of electron-deficient 1,2,3-triiodoarenes with dicarbonyl compounds afforded the highest isolated yields. Furthermore, the designed novel compounds were screened against ALK, revealing that among the 17 tested, ALK-9p, ALK-9b, ALK-9n, and ALK-9m exhibited the best docking scores using the extra-precision docking method. Molecular simulations of these compounds with ALK confirmed their stable binding behavior, compact topology, and minimal residue flexibility. Finally, binding free energy calculations using MM/PBSA and MM/GBSA methods further validated the pharmacological potential of these shortlisted hits as ALK inhibitors. These results demand prompt experimental validation to determine the promising clinical applications of these compounds in the management of cancer</div></div>","PeriodicalId":374,"journal":{"name":"Journal of Organometallic Chemistry","volume":"1028 ","pages":"Article 123526"},"PeriodicalIF":2.1,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143357118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cutting-edge research on mixed-metal MOFs: fabrication, characterization, properties, and uses

IF 2.1 3区化学

Journal of Organometallic Chemistry Pub Date : 2025-01-20 DOI: 10.1016/j.jorganchem.2025.123531

Philips C. Tagbo , Islam Ibrahim , Gehad G. Mohamed , Ngutor Simon Akiiga

{"title":"Cutting-edge research on mixed-metal MOFs: fabrication, characterization, properties, and uses","authors":"Philips C. Tagbo , Islam Ibrahim , Gehad G. Mohamed , Ngutor Simon Akiiga","doi":"10.1016/j.jorganchem.2025.123531","DOIUrl":"10.1016/j.jorganchem.2025.123531","url":null,"abstract":"<div><div>Significant strides have been made in recent years to tackle the challenges associated with metal-organic frameworks (MOFs) through the incorporation of heterometallic ions into their secondary building units (SBUs) using various synthesis techniques. The design of mixed- metal–organic frameworks (MM-MOFs) presents a promising strategy to enhance the physicochemical properties of conventional MOFs, thereby improving their performance in diverse applications such as gas storage and separation, catalysis, energy storage and conversion, theranostics, and sensing technologies. Although this field is still in its early stages, there is a growing demand for regular insights into the latest advancements, trends, and innovations associated with the design, synthesis, fabrication, and applications of MM-MOFs. As a result, this review seeks to underscore recent synthesis strategies, advanced characterization techniques, and novel applications of MM-MOFs. Special emphasis is placed on the latest methods utilized in the development of this unique class of materials, with the aim of informing a broader audience about recent breakthroughs in the synthesis of MM-MOFs.</div></div>","PeriodicalId":374,"journal":{"name":"Journal of Organometallic Chemistry","volume":"1028 ","pages":"Article 123531"},"PeriodicalIF":2.1,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143322264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Advancements in ferrocene-based burning rate catalysts: Preparations, properties, catalytic and anti-migration mechanism

IF 2.1 3区化学

Journal of Organometallic Chemistry Pub Date : 2025-01-19 DOI: 10.1016/j.jorganchem.2025.123524

Muhammad Owais Malik, Li Wang, Haojie Yu, Jinyi Liu, Basem E. Keshta, Md Alim Uddin, Abdul Basit, Khan Manqoosh Awan

{"title":"Advancements in ferrocene-based burning rate catalysts: Preparations, properties, catalytic and anti-migration mechanism","authors":"Muhammad Owais Malik, Li Wang, Haojie Yu, Jinyi Liu, Basem E. Keshta, Md Alim Uddin, Abdul Basit, Khan Manqoosh Awan","doi":"10.1016/j.jorganchem.2025.123524","DOIUrl":"10.1016/j.jorganchem.2025.123524","url":null,"abstract":"<div><div>Competent composite solid propellants (CSPs) demand high burning rates (BRs) for optimal performance. Adding burning rate catalysts (BRCs) in a propellant system is one of the key strategies to achieve the desired characteristics, as the BRCs show a settling character in enhancing the working efficiency of CSPs. Among various types of BRCs, ferrocene (Fc)-based compounds are notable for their superior catalytic performance in the burning process. This review explores the preparation of Fc derivatives, Fc-based polymers, Fc-terminated dendrimers, Fc-based MOFs, and Fc-based carbon-rich materials. Also explores the electrochemical, thermal, catalytic, and anti- migration properties of Fc-BRCs in detail. Furthermore, this review highlights the catalytic mechanism of Fc-BRCs as ammonium perchlorate (AP) decomposers as well as the anti-migration mechanism in CSPs. Additionally, a summary has been created to contrast the anti-migration and catalytic activities of different Fc-BRCs. Fc-BRCs are expected to significantly improve the combustion performance of propellants by facilitating more uniform and efficient burning. Their unique structural properties allow for improved oxidation processes, which can lead to higher energy yields and reduced soot formation. This development not only improves the reliability and effectiveness of numerous propulsion systems but also opens up new avenues for designing innovative propellant formulations and applications in the aerospace and defense sectors.</div></div>","PeriodicalId":374,"journal":{"name":"Journal of Organometallic Chemistry","volume":"1028 ","pages":"Article 123524"},"PeriodicalIF":2.1,"publicationDate":"2025-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143322267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0