Indian Journal of Transplantation最新文献

{"title":"Can donor demography or anthropometry be used as a screening tool for identifying potential low ABO-Titer plasma?","authors":"P. Pandey, S. Ranjan, D. Setya, Supriya Kumari","doi":"10.4103/ijot.ijot_131_21","DOIUrl":"https://doi.org/10.4103/ijot.ijot_131_21","url":null,"abstract":"","PeriodicalId":37455,"journal":{"name":"Indian Journal of Transplantation","volume":"58 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70754526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spectrum of infections in renal transplant recipients, factors affecting long term patient and graft outcomes over 10 years including COVID pandemic periods","authors":"Abhisek Gautam, H. Mahapatra, N. Kaur, L. Pursnani, B. Muthukumar, Amandeep Singh, S. Patil, M. Prabhakaran","doi":"10.4103/ijot.ijot_128_21","DOIUrl":"https://doi.org/10.4103/ijot.ijot_128_21","url":null,"abstract":"","PeriodicalId":37455,"journal":{"name":"Indian Journal of Transplantation","volume":"1 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70754985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Curbing proteastasis to combat antibody-mediated rejection post lung transplant","authors":"N. Sharma, Dhruva Sharma, K. Subramaniam","doi":"10.4103/ijot.ijot_33_21","DOIUrl":"https://doi.org/10.4103/ijot.ijot_33_21","url":null,"abstract":"","PeriodicalId":37455,"journal":{"name":"Indian Journal of Transplantation","volume":"1 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70755400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chylous ascites following laparoscopic donor nephrectomy: Report of a case and a brief overview","authors":"C. Sheela, R. Thomas, Manishkumar D. Yadav, K. Sasidharan","doi":"10.4103/ijot.ijot_67_22","DOIUrl":"https://doi.org/10.4103/ijot.ijot_67_22","url":null,"abstract":"","PeriodicalId":37455,"journal":{"name":"Indian Journal of Transplantation","volume":"1 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70756607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge and Attitude of Health-Care Professionals toward Organ Donation in Bahrain","authors":"AmgadEl-Baz El-Agroudy, ShamikH Shah, K. Sridharan, A. Alalwan, Khadija M Alshehabi, Fadhel Alsitri, Ali Alaradi","doi":"10.4103/ijot.ijot_86_21","DOIUrl":"https://doi.org/10.4103/ijot.ijot_86_21","url":null,"abstract":"","PeriodicalId":37455,"journal":{"name":"Indian Journal of Transplantation","volume":"1 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70758154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treating Parvovirus Triggered Refractory Hemolytic Anemia with Rituximab in Renal Transplant Recipients - A Report of Two Cases.","authors":"Chilaka Rajesh, Utkarsh Mishra, Anna Valsan, Elenjickal Elias John, Jeethu Joseph Eapen, Athul Thomas, Sabina Yusuf, Suceena Alexander, Vinoi George David, Santosh Varughese","doi":"10.4103/ijot.ijot_34_22","DOIUrl":"10.4103/ijot.ijot_34_22","url":null,"abstract":"<p><p>Parvovirus B19 is a small (26 nm), nonenveloped, single-stranded DNA (5.6-kb) virus. The only known host for parvovirus B19 is humans. Parvovirus B19 is directly cytotoxic to erythroid precursor cells of the colony- and burst-forming units. Human parvovirus B19 is the etiologic agent of erythema infectiosum and chronic pure red cell aplasia in immunocompromised individuals. Acute parvovirus B19 infection should be suspected in immunocompromised patients, who present with reticulocytopenic hemolytic anemia and thrombocytopenia. Intravenous immunoglobulin (IVIg) is the standard treatment for parvovirus-induced cytopenias. We report two cases of postrenal transplant who presented with reticulocytopenic anemia and were found to have parvovirus infection. They did not respond to conventional treatment with intravenous gamma globulin. Both patients were treated with rituximab with which they had improvement in clinical and hematological parameters. There was no previous documentation of using rituximab in the treatment of parvovirus-triggered autoimmune hemolytic anemia postrenal transplant patients. This article illustrates how rituximab will be helpful in this setting, of course, it is a new thought but requires further studies and validation.</p>","PeriodicalId":37455,"journal":{"name":"Indian Journal of Transplantation","volume":"1 1","pages":"139-142"},"PeriodicalIF":0.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7615908/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70754990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Renal transplantation in a patient with turner syndrome","authors":"R. Nerli, Ritesh Vernekar, Shoubhik Chandra, Neeraj S. Dixit, S. Ghagane","doi":"10.4103/ijot.ijot_46_22","DOIUrl":"https://doi.org/10.4103/ijot.ijot_46_22","url":null,"abstract":"","PeriodicalId":37455,"journal":{"name":"Indian Journal of Transplantation","volume":"1 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70755724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spectrum of COVID-19 infections in renal transplant recipients: A single-center case series","authors":"T. Mukherjee, R. Bonu, G. Prakash, Sundar Sankaran, S. Ballal","doi":"10.4103/ijot.ijot_52_22","DOIUrl":"https://doi.org/10.4103/ijot.ijot_52_22","url":null,"abstract":"","PeriodicalId":37455,"journal":{"name":"Indian Journal of Transplantation","volume":"1 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70756292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An understanding of the evaluation of histocompatibility testing for a deceased-donor transplant","authors":"V. Mishra, V. Raina","doi":"10.4103/ijot.ijot_111_21","DOIUrl":"https://doi.org/10.4103/ijot.ijot_111_21","url":null,"abstract":"","PeriodicalId":37455,"journal":{"name":"Indian Journal of Transplantation","volume":"18 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70754584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Utility of Apolipoprotein-1 Gene Polymorphism Screening in Donor Evaluation for Kidney Transplantation in India","authors":"Narayan Prasad, Brijesh Yadav","doi":"10.4103/ijot.ijot_116_23","DOIUrl":"https://doi.org/10.4103/ijot.ijot_116_23","url":null,"abstract":"Kidney transplantation is the treatment of choice for end-stage kidney disease patients. The living donor for kidney transplantation remains at risk of developing kidney diseases. The risk may increase when an individual has a genetic predisposition to developing kidney disease. On the other hand, inter-individual genetic diversity remains a barrier to unrestricted organ donation and transplantation. The evolution of human genome sequencing in health and diseases increases the scope of finding individuals at risk for specific kidney diseases. The question of screening the donor for genetic predisposition to kidney diseases is unanswered. The ambiguity in the association of genetic polymorphisms with the diseases and the cost of screening every individual will be a significant limitation in the current scenario.[1] In a narrative review of the current issue, Fernando et al. have advocated for testing apolipoprotein-1 (APOL-1) gene mutation in prospective kidney donors before transplantation. APOL-1 is a 14.5 kb gene located on the long arm of chromosome 22.[2] APOL-1 proteins are 398 amino acid-long peptide chains encoded by the APOL-1 gene. APOL-1 is synthesized primarily by the liver, lung, brain, and kidney, especially by podocyte and proximal convoluted tubule cells.[3] APOL-1 protein is made of 5 functional domains, namely the S-domain required for its secretion; the membrane addressing domain that senses pH and regulates cell death; the BH3 domain associated with apoptosis; the pore-forming domain; and serum resistance-associated binding domains, conferring resistance to Trypanosoma brucei, a causative organism for sleeping sickness.[2] APOL-1 plays a role in immunity and is especially protective against Trypanosoma parasites. APOL-1 reportedly regulates the immune response against infections, cell apoptosis, autophagy, ion exchange, and extracellular cholesterol transport to the liver.[3,4] Higher interferon-ɣ and tumor necrosis factor-α also induce APOL-1 secretion. A genetic mutation in the APOL-1 gene leads to cardiovascular and HIV-associated nephropathy.[5,6] The APOL-1 risk variants are G1 and G2, and G0 as wild type. Two coding variants, G1 and G2, are relevant to human phenotypes. Single-nucleotide polymorphism in G1 (having two amino acid substitutions (serine 342 glycine and isoleucine 384 methionine), and G2 (a two-amino acid deletion, del 388 asparagine, 389 tyrosine) alleles of the APOL-1 C-terminal, inhibits the binding of the Trypanosoma brucei virulence factors to the serum resistance-associated protein, resulting in lysis of parasites.[7,8] APOL-1 gene evolved in Africa over the past 10,000 years, and people moving out of these regions have taken these genetic variants with them. APOL-1 risk variant occurred in people of African ancestry, Black African, African-American, Afro-Caribbean, etc., Many African-Americans are descendants of people from West African nations and have a high prevalence of APOL1 risk alleles and APOL-","PeriodicalId":37455,"journal":{"name":"Indian Journal of Transplantation","volume":"62 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135839645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}