{"title":"Diagnostic Value of Radiographic Characteristics of Mediastinal and Hilar Lymph Nodes in Sarcoidosis.","authors":"Olcay Ayçiçek, Yılmaz Bülbül, Funda Öztuna, Tevfik Özlu, Selçuk Akkaya","doi":"10.5152/TurkThoracJ.2022.21254","DOIUrl":"https://doi.org/10.5152/TurkThoracJ.2022.21254","url":null,"abstract":"<p><strong>Objective: </strong>In this study, it was aimed to investigate the diagnostic value of thorax computed tomography, which is a non-invasive method, in diagnosing sarcoidosis.</p><p><strong>Materials and methods: </strong>In our Faculty of Medicine, Department of Chest Diseases between January 1, 2013, and July 1, 2019, the data of 816 patients who underwent endobronchial ultrasonography for mediastinal lymph node sampling and other sampling methods, such as mediastinoscopy, thoracotomy, etc., if the histopathological diagnosis could not be reached, were retrospectively screened and 192 patients (sarcoidosis: 62, non-sarcoidosis: 130 patients) who met the inclusion criteria were included in the study. Patients diagnosed with sarcoidosis and patients diagnosed with non-sarcoidosis were compared in terms of thorax computed tomography findings (medi- astinal lymph nodes and lung parenchymal involvement).</p><p><strong>Results: </strong>Right upper paratracheal (72.6 vs. 46.9%, P = .001) and paraaortic lymph node involvement (79.0% vs. 60.8%, P = .01), hilar symmetry (88.5 vs. 58.3%, P < .001), and homogeneity in lymph nodes (80.6% vs. 56.9%, P = .001) were found to be significantly higher in the sarcoidosis group. Lymph node sizes were smaller in the sarcoidosis group and the mean density (51.3 Hounsfield unit vs. 44.1 Hounsfield unit, P = .002) was significantly higher. In the multivariate logistic regression analysis, the presence of homogeneity in the lymph nodes is 4.3-fold more likely to increase sarcoidosis, the presence of hilar symmetry 9.1-fold, the involvement of the right lower paratracheal lymph node 2.7-fold, the mean lymphadenopathy density >48 Hounsfield unit 4.3-fold, the maximum diameter of lymphadenopathy less than 27.5 mm 4.7-fold.</p><p><strong>Conclusion: </strong>This study revealed that the localization, size, density, and homogeneity of mediastinal lymph nodes will help clinicians to diagnose patients with sarcoidosis without using invasive methods.</p>","PeriodicalId":37452,"journal":{"name":"Turkish Thoracic Journal","volume":"23 4","pages":"284-289"},"PeriodicalIF":0.9,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/05/2d/ttj-23-4-284.PMC9361305.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40617841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Heba Wagih Abdelwahab, Nesrein M Shalabi, Mahitab Mohamed Rashad Ghoneim, Nesrine Saad Farrag, Fatma Hamdy, Fatma Elhoseiny, Raed Elmetwally Ali
{"title":"Screening for Subclinical Interstitial Lung Disease in Rheumatoid Arthritis Patients: Functional and Radiological Methods.","authors":"Heba Wagih Abdelwahab, Nesrein M Shalabi, Mahitab Mohamed Rashad Ghoneim, Nesrine Saad Farrag, Fatma Hamdy, Fatma Elhoseiny, Raed Elmetwally Ali","doi":"10.5152/TurkThoracJ.2022.21263","DOIUrl":"https://doi.org/10.5152/TurkThoracJ.2022.21263","url":null,"abstract":"<p><strong>Objective: </strong>Interstitial lung disease is the most frequent lung symptom of rheumatoid arthritis and is a significant contributor to morbid- ity. As a result, the target of this research was to measure the frequency of radiological and functional abnormalities in rheumatoid arthritis patients who did not have any respiratory symptoms.</p><p><strong>Material and methods: </strong>This study consists of 30 patients diagnosed with rheumatoid arthritis. All involved cases were exposed to entire history taking and clinical examination. All patients were examined by high-resolution computed tomography and pulmonary function tests.</p><p><strong>Results: </strong>According to the computed tomography visual score, 73.3% showed interstitial lung disease. The most common abnormalities were reticular patterns (46.7%) followed by nodular patterns (40%) and septal lines (23.3%). However, 36% of the patients had a normal pulmonary function, while 32% had a small airway affection, 20% had restrictive lung disease, and 12% had obstructive lung disease. A significant association was found between supine expiratory volume and computed tomography visual score. Results showed no associa- tion between interstitial lung disease and all lung function test parameters.</p><p><strong>Conclusion: </strong>Subclinical interstitial lung disease is frequent among rheumatoid arthritis patents. A combination of pulmonary func- tion tests with computed tomography is essential to enhance the recognition of subclinical interstitial lung disease as normal pulmonary function alone cannot exclude its presence.</p>","PeriodicalId":37452,"journal":{"name":"Turkish Thoracic Journal","volume":"23 4","pages":"261-267"},"PeriodicalIF":0.9,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/6f/3f/ttj-23-4-261.PMC9361088.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40594896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Incidence of Mechanical Ventilation Adverse Events in Critically Ill Children in a Tertiary Pediatric Intensive Care Unit.","authors":"Capan Konca, Mehmet Tekin, Ahmet Kucuk","doi":"10.5152/TurkThoracJ.2022.21253","DOIUrl":"10.5152/TurkThoracJ.2022.21253","url":null,"abstract":"<p><strong>Objective: </strong>Despite the clinical use of mechanical ventilation having well-documented benefits, it can be associated with complica- tions and adverse physiological effects that can impact mortality rates. There are few studies that examine complications associated with mechanical ventilation in children and the factors associated with complications in detail. This study aimed to investigate adverse events associated with mechanical ventilation in pediatric patients and to compare the epidemiology of complications associated with mechanical ventilation.</p><p><strong>Material and methods: </strong>The medical records of patients in a tertiary care pediatric intensive care unit who were mechanically ventilated between January 1, 2013, and July 31, 2017, were evaluated.</p><p><strong>Results: </strong>A total of 187 patients were included in the study, 105 boys (56.1%) and 82 girls (43.9%), and 45 (24.1%) patients experienced complications. The total number of mechanical ventilation days was 1100. Atelectasis (12.3%), post-extubation stridor (8.5%), ventilator- associated pneumonia (5.4%), and pneumothorax (5.4%) were most commonly observed complications.</p><p><strong>Conclusion: </strong>Complications of mechanical ventilation in the pediatric population still occur frequently. In this study, the incidence of atelectasis was high, and also, incidences of ventilator-associated pneumonia and pneumothorax were low.</p>","PeriodicalId":37452,"journal":{"name":"Turkish Thoracic Journal","volume":"23 4","pages":"277-283"},"PeriodicalIF":0.8,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/33/9b/ttj-23-4-277.PMC9361204.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40617840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Coexistence of Multiple Pulmonary Sclerosing Pneumocytoma and Scleroderma-Rheumatoid Arthritis Overlap Syndrome: A Case Report.","authors":"Hülya Abalı, Fatma Tokgöz Akyıl, Seda Tural Önür, Neslihan Akanıl Fener, Aysun Ölçmen","doi":"10.5152/TurkThoracJ.2022.21273","DOIUrl":"https://doi.org/10.5152/TurkThoracJ.2022.21273","url":null,"abstract":"<p><p>Pulmonary sclerosing pneumocytoma is a rare, low-grade pulmonary tumor observed as unilateral or bilateral multiple nodules at a rate of 4%-5%. Among the autoimmune connective tissue disorders, those most commonly associated with lung malignancies are sclero- derma and rheumatoid arthritis. In this study, we report a rare case of a 55-year-old middle-aged Asian woman with slow-growing bilat- eral multiple pulmonary sclerosing pneumocytoma and scleroderma-rheumatoid arthritis overlap syndrome. The autoimmune disorders and pulmonary fibrosis of this case might have led to the development of PSP.</p>","PeriodicalId":37452,"journal":{"name":"Turkish Thoracic Journal","volume":"23 4","pages":"302-305"},"PeriodicalIF":0.9,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/2e/24/ttj-23-4-302.PMC9361127.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40613990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fatma Tokgöz Akyıl, Seda Tural Önür, Sinem Sökücü, Hülya Abalı, Neslihan Boyracı, Elif Çayır, Sedat Altın
{"title":"Lifestyle Changes and Exacerbation Frequency of COPD in Times of the Pandemic.","authors":"Fatma Tokgöz Akyıl, Seda Tural Önür, Sinem Sökücü, Hülya Abalı, Neslihan Boyracı, Elif Çayır, Sedat Altın","doi":"10.5152/TurkThoracJ.2022.21165","DOIUrl":"10.5152/TurkThoracJ.2022.21165","url":null,"abstract":"<p><strong>Objective: </strong>The objective of this study is to analyze chronic obstructive pulmonary disease exacerbation rates and the effect of patients' behavioral changes on the exacerbations during the pandemic.</p><p><strong>Material and methods: </strong>This study was conducted in a reference hospital for chest diseases and patients who were hospitalized with an exacerbation of chronic obstructive pulmonary disease between March 11, 2019, and March 11, 2020, were designated. Patients' chronic obstructive pulmonary disease exacerbations requiring emergency department visits and/or hospitalization were com- pared between the pre-pandemic and pandemic periods. Each patient was surveyed with 25 questions using telemedicine.</p><p><strong>Results: </strong>Of all the 256 patients, 203 (79%) were male and the mean age was 66 ± 10 years. Compared to the previous year, emer- gency department visits and hospitalizations in our hospital were significantly lower and less frequent (P < .0001, for both). Smoking habits decreased in 9% of patients, and 60% had hardly spent time outdoors. Only 3 patients reported to spend time indoors. The household mask-use rate while contacting the patient was 50%. As a chronic obstructive pulmonary disease patient, 33% expressed themselves as \"feeling better.\" Overall, 92(36%) patients were recorded not to have any exacerbation, and 34 (13%) to have no attacks of worsening were managed at home. Novel exacerbation risk was found to independently correlate with younger age (odds ratio: 0.944, CI: 0.904-0.986, P = .010) and having more frequent episodes of exacerbation in the pre-pandemic period (odds ratio: 1.2, CI: 1.025-1.405, P = .023).</p><p><strong>Conclusion: </strong>Chronic obstructive pulmonary disease patients specifically benefited from confinements, restrictions, and lifestyle changes. Further studies are needed to better identify the most critical factors leading to these positive outcomes. A permanent patient management guideline for chronic obstructive pulmonary disease patients could be formulated where the weight of lifestyle factors is elevated.</p>","PeriodicalId":37452,"journal":{"name":"Turkish Thoracic Journal","volume":"23 3","pages":"210-217"},"PeriodicalIF":0.8,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/29/33/ttj-23-3-210.PMC9450222.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9546672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Predictive Role of Psychological Status and Disease Severity Indexes on Quality of Life Among Patients with Non-CF Bronchiectasis.","authors":"Berrin Ceyhan, Melahat Bekir, Derya Kocakaya, Sehnaz Olgun Yildizeli, Semiha Emel Eryuksel","doi":"10.5152/TurkThoracJ.2021.21142","DOIUrl":"https://doi.org/10.5152/TurkThoracJ.2021.21142","url":null,"abstract":"<p><strong>Objective: </strong>Bronchiectasis is a chronic suppurative lung disease that significantly impacts the patients' quality of life. Aim of this study is to evaluate the relationship between life of quality and patient's psychological status and bronchiectasis disease severity indexes in patients with non-Cystic Fibrosis (CF) bronchiectasis. We also aimed to investigate the validity and reliability of Turkish version of Quality-of-Life Questionnaire-Bronchiectasis (QoL-B V3.1) in Turkish adult bronchiectatic patients.</p><p><strong>Material and methods: </strong>90 stable non-CF bronchiectatic adult patients were enrolled into this study. At baseline, dyspnea score, BMI, lung function tests, sputum cultures, number of exacerbations and hospital admissions, disease severity indexes were recorded. All of the participants underwent quality of life assessment using both QoL-B V3.1 and of Short-Form (SF)-36 questionnaires, psychological status was evaluated by using HADS (Hospital Anxiety and Depression Scale).</p><p><strong>Results: </strong>In all study participants, anxiety was diagnosed in 27/90 (30%) of patients and depression was diagnosed in 37/90 (41%) of patients. Patients with anxiety and depression had lower quality of life scores in various domains (p:0.026-p:0.001) and HADS scores negatively correlated with several quality-of-life domains (r=-0.216 - r=- 0.343). Female patients had higher risk for depression (55% vs 22%, p:0.002) and worse quality of life than males (p:0.016-p:0.038). Several life quality scores of both instruments were worse in patients with moderate-severe disease severity indexes when compared with those of mild groups. Moreover, Turkish version of newly described QoL-B V3.1 questionnaire was found to be reliable and valid instrument to evaluate the quality of life.</p><p><strong>Conclusion: </strong>These results emphasize the importance of mental health and disease severity as significant determinants of the life quality in patients particularly female patients with non-CF bronchiectasis.</p>","PeriodicalId":37452,"journal":{"name":"Turkish Thoracic Journal","volume":"23 1","pages":"17-24"},"PeriodicalIF":0.9,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/31/77/ttj-23-1-17.PMC9450191.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39881561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Case of Prolonged Viral Shedding: Chronic, Intermittan COVID-19?","authors":"Bilkay Serez Kaya, İlker Yılmam, Ebru Çakır Edis, Derya Karabulut, Tülin Elmaslar Mert, Canan Eryıldız, Muzaffer Demir","doi":"10.5152/TurkThoracJ.2022.21141","DOIUrl":"https://doi.org/10.5152/TurkThoracJ.2022.21141","url":null,"abstract":"<p><p>COVID-19 is a pandemic that has been affecting the entire world and has caused the death of approximately 2.8 million people. Although the duration of viral shedding varies, an average of 7-10 days is accepted. It is still unclear whether prolonged viral shedding means prolonged contagious period and whether COVID-19 will become chronic or not. This article presents a case with hematological malignancy (lymphoma) with the longest polymerase chain reaction positivity that we could find in the literature (110 days in total).</p>","PeriodicalId":37452,"journal":{"name":"Turkish Thoracic Journal","volume":"23 1","pages":"85-88"},"PeriodicalIF":0.9,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/39/3b/ttj-23-1-85.PMC9450004.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39882002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alperen Ergün, Ayşegül Bekar, Bedran Aras, Canan Dere, Doğukan Tekneci, Gamze Sarıçiçek, Selin Naz Akdere, Semi Telli, Şamil Berkay Pehlivanlı, Deren Özyurek Ucael, Mustafa Enes Özden, Ercüment Altıntaş, Dilek Aslan
{"title":"Determination of Novel Coronavirus Disease (COVID-19) Vaccine Hesitancy Using a Systematic Review Approach Based on the Scientific Articles in PubMed Database.","authors":"Alperen Ergün, Ayşegül Bekar, Bedran Aras, Canan Dere, Doğukan Tekneci, Gamze Sarıçiçek, Selin Naz Akdere, Semi Telli, Şamil Berkay Pehlivanlı, Deren Özyurek Ucael, Mustafa Enes Özden, Ercüment Altıntaş, Dilek Aslan","doi":"10.5152/TurkThoracJ.2022.21082","DOIUrl":"10.5152/TurkThoracJ.2022.21082","url":null,"abstract":"<p><strong>Objective: </strong>Publications on vaccine hesitancy and the novel coronavirus disease 2019 in the scientific literature are increasing every day. An examination of their content will help to eliminate the existing negativity related to vaccine hesitancy through scientific methods. Hence, a systematic approach to the prevention of vaccine hesitancy worldwide can be developed. This article aims to survey how vaccine hesitancy is addressed in the PubMed articles about \"vaccine hesitancy\" over the novel coronavirus disease, for which the MeSH criteria have been published; to understand their recommendations for the prevention of vaccine hesitancy; to evaluate any related research described as \"cross-sectional,\" \"case-control,\" and \"cohort\" according to Strengthening the Reporting of Observational Studies in Epidemiology criteria; and to contribute to the current literature on the subject.</p><p><strong>Material and methods: </strong>This study is planned to use a systematic review format and STROBE checklist was used to evaluate the articles accessed from PubMed database. Microsoft Excel was used as the data calculation tool.</p><p><strong>Results: </strong>Sixty-five (81.3%) of the 80 articles investigated in the scope of this study mention \"vaccine.\" While 64 articles (80%) discuss the determination of vaccine hesitancy, 57 (71.3%) articles address its prevention. The keyword \"COVID-19\" is used in 61 articles (79.2%). The second most frequently used keyword is \"vaccine hesitancy\" (n = 37, 48.1%), followed by \"vaccine\" (n = 25, 32.5%). Twenty-nine (48%) of the reviewed articles originate from the WHO American Continents. The second most represented region of research is the European Region (n = 21, 35%), followed by the South East Asian Region (n = 5, 8%).</p><p><strong>Conclusion: </strong>This study illustrates the recent situation for the coronavirus disease 2019 vaccine and reveals the presence of a vaccine hesitancy. Vaccine hesitancy is a risk factor that could prevent herd immunity. The systematic review of scientific articles should continue with improvements in order to tackle the problem as exemplified by the present study. Other checklists as well as STROBE checklist are recommended to be used in similar studies to have more objective conclusions.</p>","PeriodicalId":37452,"journal":{"name":"Turkish Thoracic Journal","volume":"23 1","pages":"70-84"},"PeriodicalIF":0.8,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b2/49/ttj-23-1-70.PMC9450048.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39882003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dilara Atasoy, Nazım Çetinkaya, Halil Çaylak, Rağıp Sarıismailoğlu, Mehmet Haydar Atalar
{"title":"Comparison of Different Slice Thicknesses on Chest Computed Tomography for Evaluation of COVID-19- Associated Pneumonia.","authors":"Dilara Atasoy, Nazım Çetinkaya, Halil Çaylak, Rağıp Sarıismailoğlu, Mehmet Haydar Atalar","doi":"10.5152/TurkThoracJ.2022.21120","DOIUrl":"https://doi.org/10.5152/TurkThoracJ.2022.21120","url":null,"abstract":"<p><strong>Objective: </strong>To compare the value of chest computed tomography at 1-mm and 5-mm slice thickness in terms of computed tomography severity score and computed tomography evaluation time in the diagnosis of COVID-19.</p><p><strong>Material and methods: </strong>Sixty-five patients were included in the study group who are reverse-transcription polymerase chain reaction-positive for COVID-19 and had chest computed tomography. The 1 mm and 5 mm reconstructed images were evaluated in 2 different sessions with 4-week intervals by 2 certificated general radiologists. The presence of COVID-19-related findings, COVID-19 final category, and evaluation time were recorded. Thin and thick slices were compared for these variables and inter-reader reliability calculated with the Statistical Package for the Social Sciences (SPSS) for Windows.</p><p><strong>Results: </strong>There was no significant difference between the COVID-19-related findings on thorax computed tomography between 1-mm and 5-mm slices except crazy paving appearance, microvascular enlargement, and septal thickening. The frequency of the final categories of computed tomography results was consistent between the thick and thin slices. The computed tomography assessment time was significantly lower in 5 mm slices. The inter-reader reproducibility analysis results demonstrated good and excellent reproducibility of measurements between readers for both slice thicknesses.</p><p><strong>Conclusion: </strong>It was found that 5-mm reconstruction thickness of chest computed tomography can be employed for the initial detection of COVID-19-related findings and the final diagnostic category-related COVID-19 rather than 1-mm slices with a faster availability of results which can be beneficial on pandemic hospitals.</p>","PeriodicalId":37452,"journal":{"name":"Turkish Thoracic Journal","volume":"23 1","pages":"32-37"},"PeriodicalIF":0.9,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/f1/ad/ttj-23-1-32.PMC9449893.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39881996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}