{"title":"Clinical, Parasitological, and Serological Follow-Up of Dogs with Sarcoptic Mange Treated Orally with Lotilaner.","authors":"F Moog, J Brun, P Bourdeau, M C Cadiergues","doi":"10.1155/2021/6639017","DOIUrl":"10.1155/2021/6639017","url":null,"abstract":"<p><p>Canine sarcoptic mange is a highly pruritic and contagious skin disease caused by the mite <i>Sarcoptes scabiei</i> var. <i>canis</i>. This case series describes the clinical, parasitological, and serological follow-up of a cohort of eight adult Saint Bernard dogs with confirmed sarcoptic mange, treated orally with lotilaner. Dogs were evaluated initially and after 14 days and 1, 2, 3, 4, 6, and 12 months for skin lesions, pruritus severity, presence of parasites, and <i>Sarcoptes</i>-IgG levels. A serological indoor allergy panel (IgE) was obtained for seven dogs at day 0 and repeated 12 months later in five dogs to assess potential cross-reactivity between <i>S. scabiei</i> and environmental allergens. Lotilaner was administered to each dog according to the manufacturer's instructions and was repeated after one and two months without any concurrent therapeutic measure or modification of the husbandry conditions. Pruritus ceased after two weeks. The cutaneous score was reduced by 47%, and skin scrapings were negative for all but three animals. All skin scrapings were negative after one month. Lesions were absent after two months. Serological levels decreased gradually, but more slowly than the skin lesions, and two dogs out of six remained positive in the absence of skin lesions or symptoms. All dogs initially tested positive for dust mites and/or storage mites. The IgE titres remained unchanged 12 months later in the five tested dogs. This case report demonstrates the efficacy of lotilaner on scabies in a cohort of infested dogs under natural conditions and the potential antigenic cross-reaction of <i>S. scabiei</i> with house dust and storage mites.</p>","PeriodicalId":37339,"journal":{"name":"Case Reports in Veterinary Medicine","volume":"2021 ","pages":"6639017"},"PeriodicalIF":0.0,"publicationDate":"2021-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7857930/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25363685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Barbara Brunetti, Luisa Vera Muscatello, Louis J DeTolla, Giancarlo Avallone
{"title":"Unusual Myoid Differentiation in a Canine Benign Mixed Mammary Tumour.","authors":"Barbara Brunetti, Luisa Vera Muscatello, Louis J DeTolla, Giancarlo Avallone","doi":"10.1155/2021/6615256","DOIUrl":"https://doi.org/10.1155/2021/6615256","url":null,"abstract":"<p><p>This report describes an unusual mesenchymal differentiation in a canine benign mixed mammary tumour. A 13-year-old crossbreed female dog was submitted to surgery to remove an inguinal mammary nodule. The tumour was composed of mammary epithelium and mesenchymal populations, not only of cartilage and bone but also of myoid cells. PTAH demonstrated cross striation of striated muscle, and immunohistochemistry highlighted striated muscle expressing desmin and calponin, and smooth muscle expressing desmin, SMA, and calponin. The tumour was diagnosed as a benign mixed tumour with leio- and rhabdomyoid differentiation. There was no tumour recurrence after one year of clinical follow-up. In conclusion, the well-differentiated features of leiomyocytes and rhabdomyocytes and the growth pattern define the benign origin of the mesenchymal component, which has been confirmed by a benign outcome; therefore, the knowledge of this kind of differentiation is helpful to avoid misdiagnoses.</p>","PeriodicalId":37339,"journal":{"name":"Case Reports in Veterinary Medicine","volume":"2021 ","pages":"6615256"},"PeriodicalIF":0.0,"publicationDate":"2021-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7850841/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25354139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The First Case Report of Ectopic Hepatic Tissue in a Guinea Pig.","authors":"Tohru Kimura, Kengo Inaka","doi":"10.1155/2021/6626299","DOIUrl":"https://doi.org/10.1155/2021/6626299","url":null,"abstract":"<p><p>Ectopic hepatic tissue is an extremely rare developmental abnormality in human beings. Although this lesion is likewise rare in veterinary medicine and there were sparse reports in several species such as dogs, cats, cows, and calves, we incidentally encountered ectopic hepatic tissue in a guinea pig. In the case of guinea pigs, we report for the first time the occurrence of ectopic hepatic tissue implanted in the gallbladder. The healthy guinea pig remained asymptomatic, and its macroscopic findings also showed no abnormalities. Hematological examinations exhibited moderate decreases in white cell counts, hemoglobin concentrations, and packed cell volume ratio. Serum biochemical examinations showed decreases in total protein and albumin and increases in glucose levels, alkaline phosphatase, lactate dehydrogenase, creatine kinase, and <i>γ</i>-glutamyl transpeptidase. There were slight changes in electrolytes (Cl, Ca, and Mg) and inorganic phosphorus, indicating minor deviations from physiologic ranges. An increase in TBIL concentrations was not found in this examination. Histopathological examination revealed the presence of normal hepatic structures (hepatocytes and hepatic cords) within the wall of the normal gallbladder. The vascular and bile duct structures and portal triads were not observed in the ectopic hepatic tissue. In conclusion, this microectopic hepatic tissue in a guinea pig was characterized by the embedded structures of hepatic tissues, without foreign body reaction.</p>","PeriodicalId":37339,"journal":{"name":"Case Reports in Veterinary Medicine","volume":"2021 ","pages":"6626299"},"PeriodicalIF":0.0,"publicationDate":"2021-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7850827/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25354140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Christian Mayer, Steffen Ormanns, Monir Majzoub-Altweck
{"title":"Histomorphology and Immunohistochemistry of a Congenital Nephromegaly Demonstrate Concurrent Features of Heritable and Acquired Cystic Nephropathies in a Girgentana Goat (<i>Capra falconeri</i>).","authors":"Christian Mayer, Steffen Ormanns, Monir Majzoub-Altweck","doi":"10.1155/2021/8749158","DOIUrl":"https://doi.org/10.1155/2021/8749158","url":null,"abstract":"<p><p>Polycystic kidney diseases (PKD) represent frequent congenital and adult nephropathies in humans and domestic animals. This report illustrates an uncommon state of congenital PKD in a girgentana goat (<i>Capra falconeri</i>). A stillborn female goat kid was submitted for postmortem examination and underwent macroscopic and microscopic examination. The kidneys showed a bilateral nephromegaly and a perpendicular polycystic altered texture of the renal parenchyma. Renal tissue sections were comprehensively investigated by histopathology (overview and special stains), immunohistochemistry (CD10, CD117, pan-cytokeratin, cytokeratin 7, E-cadherin, Pax2, Pax8, and vimentin), and electron microscopy (SEM, TEM). Histopathology of renal tissue sections revealed polycystic alterations of the renal parenchyma as well as conspicuous polypoid proliferates/projections of the renal tubular epithelium, which showed clear cell characteristics. Furthermore, epithelial projections were indicative for epithelio-mesenchymal-transition, cellular depolarization, and strong expression of differentiation markers Pax2, Pax8, and CD10. Ultrastructural morphology of the projections was characterized by numerous diffusely distributed, demarked round cytoplasmic structures and several apico-lateral differentiations. Additionally, hepatic malformations comprising biliary duct proliferation with saccular dilation and bridging fibrosis were observed. Notably, this report describes the first case of a congenital cystic nephropathy with overlapping features of heritable and acquired nephropathies in any species. Epithelio-mesenchymal-transition and altered cadherin expression seem to be crucial components of a suspected pathomechanism during cystogenesis.</p>","PeriodicalId":37339,"journal":{"name":"Case Reports in Veterinary Medicine","volume":"2021 ","pages":"8749158"},"PeriodicalIF":0.0,"publicationDate":"2021-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7837792/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25325634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aria L Guarino, Albert B Jeon, Jeffrey R Abbott, Richard C Hill
{"title":"Pulmonary Sarcomatoid Carcinoma Associated with Arterial Thromboembolism in a Cat.","authors":"Aria L Guarino, Albert B Jeon, Jeffrey R Abbott, Richard C Hill","doi":"10.1155/2021/8849515","DOIUrl":"https://doi.org/10.1155/2021/8849515","url":null,"abstract":"<p><p>A 14-year-old, neutered male domestic shorthair cat presented for acute monoparesis with physical exam findings and biochemical data supportive of a distal arterial thromboembolism. Thoracic radiographs revealed an alveolar pattern in the right middle lung lobe and multifocal nodules in other lung lobes. A pulmonary mass was found on necropsy, which was composed of both carcinomatous and sarcomatous components, confirmed with cytokeratin and vimentin immunohistochemistry. Using the World Health Organization classification scheme for mixed pulmonary tumors, this tumor would be characterized as a pleomorphic squamous cell carcinoma under the umbrella term of pulmonary sarcomatoid carcinoma. The World Health Organization classification of mixed pulmonary tumors and its application to previously reported mixed pulmonary tumors in companion animals is discussed. This is the first reported case of this tumor type in a cat, as well as the first report of this tumor type associated with an arterial thromboembolism in any veterinary species.</p>","PeriodicalId":37339,"journal":{"name":"Case Reports in Veterinary Medicine","volume":"2021 ","pages":"8849515"},"PeriodicalIF":0.0,"publicationDate":"2021-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822706/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38873054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Rare Case of Whole Body Distributed Hair Follicle Cysts in a Dog","authors":"海峰 陈","doi":"10.12677/ACRPVM.2021.101001","DOIUrl":"https://doi.org/10.12677/ACRPVM.2021.101001","url":null,"abstract":"","PeriodicalId":37339,"journal":{"name":"Case Reports in Veterinary Medicine","volume":"1 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66126949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical Identification and Treatment of Low-Blood Potassium Postpartum Paralysis and Low-Blood Magnesium Postpartum Paralysis in Cows","authors":"侯 引绪","doi":"10.12677/ACRPVM.2021.102004","DOIUrl":"https://doi.org/10.12677/ACRPVM.2021.102004","url":null,"abstract":"","PeriodicalId":37339,"journal":{"name":"Case Reports in Veterinary Medicine","volume":"72 1","pages":"20-27"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66127020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Study on Clinical Prevention and Treatment of Liver Abscess in the Cow","authors":"侯 引绪","doi":"10.12677/ACRPVM.2021.102003","DOIUrl":"https://doi.org/10.12677/ACRPVM.2021.102003","url":null,"abstract":"","PeriodicalId":37339,"journal":{"name":"Case Reports in Veterinary Medicine","volume":"10 1","pages":"15-19"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66127009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Drew W Koch, Katharine M Simpson, Jeremiah T Easley, Eileen S Hackett
{"title":"Laparoscopic Ovariectomy in a Domestic Yak.","authors":"Drew W Koch, Katharine M Simpson, Jeremiah T Easley, Eileen S Hackett","doi":"10.1155/2020/8886670","DOIUrl":"https://doi.org/10.1155/2020/8886670","url":null,"abstract":"<p><p>Owners of a juvenile domestic yak elected bilateral ovariectomy to prevent future reproduction. The yak was noted to be healthy at presentation. Both ovaries were removed using a laparoscopic approach as follows: after induction and maintenance of general inhalant anesthesia, 15 degrees Trendelenburg positioning was required to view the ovaries. Ovariectomy was conducted within a surgical time of 50 minutes. Due to the small ovarian size, portal enlargement was not necessary for removal. Mild hemorrhage from the left ovarian pedicle was controlled with application of a vessel-sealing device. Postoperative complications were not encountered during hospitalization. At 12 months following surgery, the yak was healthy, and the owner was highly satisfied with the procedure. The described approach was successful for performing laparoscopic ovariectomy in a juvenile yak. Positioning for surgery was similar to other small ruminant species. Further case enrollment is needed to optimize the surgical approach and better describe clinical outcomes.</p>","PeriodicalId":37339,"journal":{"name":"Case Reports in Veterinary Medicine","volume":"2020 ","pages":"8886670"},"PeriodicalIF":0.0,"publicationDate":"2020-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2020/8886670","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38614721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}