Sleep Medicine Research最新文献_第5页

Different Course of Narcolepsy Diagnosed by Multiple Sleep Latency Test: A Single Center Experience 多重睡眠潜伏期测试诊断不同病程的嗜睡症：单中心经验

Sleep Medicine Research Pub Date : 2022-12-31 DOI: 10.17241/smr.2022.01529

Hong-Shik Chun, Sung-Min Kim, Tae-Won Kim, Y. Um, Jong-Hyun Jeong, H. Seo, Seung-Chul Hong

{"title":"Different Course of Narcolepsy Diagnosed by Multiple Sleep Latency Test: A Single Center Experience","authors":"Hong-Shik Chun, Sung-Min Kim, Tae-Won Kim, Y. Um, Jong-Hyun Jeong, H. Seo, Seung-Chul Hong","doi":"10.17241/smr.2022.01529","DOIUrl":"https://doi.org/10.17241/smr.2022.01529","url":null,"abstract":"Background and Objective Several studies have raised questions about determining the diagnosis of the narcolepsy using multiple sleep latency test (MSLT). In this study, we investigated the diagnostic change in narcolepsy type 1 (NT1) and narcolepsy type 2 (NT2) using MSLT with long-term interval.Methods In this retrospective study, the demographic characteristics, polysomnography (PSG), and MSLT parameters were compared at the baseline between the NT1 and NT 2 patients. Then, MSLT re-tests were conducted with a mean follow-up of 8.48 years in patients with NT 1 and 7.05 years with NT 2.Results Seventy-four patients (58 with NT1 and 16 with NT2) were investigated in this study. At the baseline, demographic data showed a larger body mass index value, more sleep paralysis, and hypnogogic hallucination in NT 1 compared to NT 2. Also, at baseline MSLT, shorter mean sleep latency and higher number of sleep onset rapid eye movement periods (SOREMPs) were observed in the NT 1 than those of the NT 2. On follow-up MSLT, 6.9% (n = 4) patients with NT1 and 50% (n = 8) patients with NT2 did not satisfy the previous diagnosis. Furthermore, in all the groups who had the change in repeated-MSLT, the groups with less than 2 SOREMPs observed to be accompanied by negative MSL at follow-up.Conclusions The result of MSLT was observed not to be stable in the diagnosis of NT 2 at the study. Therefore, it is recommended to repeat MSLT at regular intervals and do a prospective multi-site survey for the accurate confirmation of a diagnosis of central hypersomnia.","PeriodicalId":37318,"journal":{"name":"Sleep Medicine Research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41573686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Usefulness of ApneaLinkTM as a Screening Test for Diagnosis of Obstructive Sleep Apnea ApneaLinkTM筛查试验在诊断阻塞性睡眠呼吸暂停中的作用

Sleep Medicine Research Pub Date : 2022-09-30 DOI: 10.17241/smr.2022.01340

Young Bin Yun, W. Bae, Sangjun Kim, Young Gun Kim, Sang Hoo Park

{"title":"The Usefulness of ApneaLinkTM as a Screening Test for Diagnosis of Obstructive Sleep Apnea","authors":"Young Bin Yun, W. Bae, Sangjun Kim, Young Gun Kim, Sang Hoo Park","doi":"10.17241/smr.2022.01340","DOIUrl":"https://doi.org/10.17241/smr.2022.01340","url":null,"abstract":"Background and Objective To investigate the usefulness of ApneaLinkTM as a screening test for obstructive sleep apnea by analyzing the correlation between ApneaLinkTM and polysomnography (PSG).Methods From January 1, 2018 to December 31, 2020, patients who visited the sleep clinic with snoring, sleep apnea, and excessive daytime sleepiness at the otolaryngology department of this hospital were subjected to both standard sleep PSG and ApneaLinkTM. Correlations of Apnea-Hypopnea Index (AHI) and Respiratory Disturbance Index (RDI) in standard PSG with AHI and Risk Indicator (RI) in ApneaLinkTM were investigated. To determine the usefulness of ApneaLinkTM as a screening test for patients with moderate or severe sleep apnea, cut-off values of AHI and RI of ApneaLinkTM were determined using receiver operating characteristic (ROC) curves.Results The correlation coefficient between AHI in PSG and AHI or RI in ApneaLinkTM was both 0.647, showing a high positive correlation. The correlation coefficient between RDI in PSG and AHI or RI in ApneaLinkTM was both 0.637, showing a high positive correlation. When the cut-off value of AHI with the ApneaLinkTM test was 19.0, it showed a sensitivity of 76.29% and a specificity of 78.95%, which could be expected to produce more than 15 of RDI in PSG.Conclusions Through this study, it was found that ApneaLinkTM could be used as a screeningtest for obstructive sleep apnea.","PeriodicalId":37318,"journal":{"name":"Sleep Medicine Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49641765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Obstructive Sleep Apnea in a 2-Year-Old Down Syndrome Child: Successful Management With Adenotonsillectomy Followed by Rapid Maxillary Expansion Treatment 2岁唐氏综合症儿童的阻塞性睡眠呼吸暂停:腺扁桃体切除术后快速上颌扩张治疗的成功管理

Sleep Medicine Research Pub Date : 2022-09-30 DOI: 10.17241/smr.2022.01319

M. J. Park, Y. Kim, Yoo-Sam Chung

{"title":"Obstructive Sleep Apnea in a 2-Year-Old Down Syndrome Child: Successful Management With Adenotonsillectomy Followed by Rapid Maxillary Expansion Treatment","authors":"M. J. Park, Y. Kim, Yoo-Sam Chung","doi":"10.17241/smr.2022.01319","DOIUrl":"https://doi.org/10.17241/smr.2022.01319","url":null,"abstract":"Due to glossal and craniofacial skeletal abnormalities, children with Down syndrome (DS) are prone to obstructive sleep apnea (OSA), thus demanding an increased necessity for an earlier diagnosis and more strict control for OSA. Adenotonsillectomy (T&A op) is an effective surgical treatment method to reduce OSA in children. Nevertheless, it should be noted that T&A op in DS children might be insufficient to completely resolve OSA and that extra care is needed when performing a T&A op for airway obstruction in DS during the immediate postoperative period. The objective of the present study was to report a case of a 2-year-old male DS patient with severe OSA (apnea-hypopnea index [AHI] of 61.7/hr) which was consequently reduced to moderate OSA (AHI of 7.6/hr), followed by reduction to mild OSA (AHI of 4.8/hr) with an one-year of rapid maxillary expansion (RME) device application. With a 2-year application of the RME device, the hard palate width in the 1st and 2nd molar region was increased to 5.86 mm and 5.26 mm, respectively. This is the first case report describing that a severe OSA is reduced to moderate OSA with T&A op and further reduced to mild OSA with an RME device application.","PeriodicalId":37318,"journal":{"name":"Sleep Medicine Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41913272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Therapeutic Effect of Extended Uvulopalatal Flap Surgery in Patients With Obstructive Sleep Apnea 延长悬垂腭瓣手术治疗阻塞性睡眠呼吸暂停的疗效观察

Sleep Medicine Research Pub Date : 2022-09-30 DOI: 10.17241/smr.2022.01298

Jae-Yoon Kang, Se Yeon Im, Han Wool John Sung, M. Choi, Soo-Kyoung Park, Yong Min Kim

{"title":"Therapeutic Effect of Extended Uvulopalatal Flap Surgery in Patients With Obstructive Sleep Apnea","authors":"Jae-Yoon Kang, Se Yeon Im, Han Wool John Sung, M. Choi, Soo-Kyoung Park, Yong Min Kim","doi":"10.17241/smr.2022.01298","DOIUrl":"https://doi.org/10.17241/smr.2022.01298","url":null,"abstract":"Background and Objective Although numerous studies have reported surgical results of uvulopalatopharyngoplasty, efficacies of extended uvulopalatal flap (EUPF) surgery have only been reported in a few studies. Thus, the aim of this study was to evaluate the success rate of EUPF and investigate the advantage and practicality of this surgery.Methods Medical records of patients who underwent EUPF surgery were retrospectively analyzed. Through medical record analysis, demographic information was confirmed. Postoperative polysomnography (PSG) results were divided into a surgical ‘success’ group and a ‘failure’ group. Patients’ PSG results, questionnaires, and cephalometry were comparatively analyzed.Results All sleep parameters of PSG except rapid eye movement latency and hypopnea index were significantly improved after surgery. Ten patients were in the success group (success rate, 33.3%) and 20 patients were in the failure group. Among preoperative PSG parameters, apnea-hypopnea index, apnea index, and number of awakenings showed significant differences between the two groups. However, there were no significant differences in results of cephalometry or Friedman stage between the two groups.Conclusions The EUPF surgery can change sleep factors and improve subjective symptoms in obstructive sleep apnea patients. It could be considered as one of the treatment options for patients with surgical indications, although its success rate was only 33.3%.","PeriodicalId":37318,"journal":{"name":"Sleep Medicine Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43598902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of Atypical Antipsychotic Medications on the Risk of Obstructive Sleep Apnea in Individuals With Schizophrenia 非典型抗精神病药物对精神分裂症患者阻塞性睡眠呼吸暂停风险的影响

Sleep Medicine Research Pub Date : 2022-09-30 DOI: 10.17241/smr.2022.01326

Habibolah Khazaie, Siamand Mazhar, A. Moghadam, M. R. Ghadami, Sepideh Khazaie, A. Parvizifard

{"title":"Effect of Atypical Antipsychotic Medications on the Risk of Obstructive Sleep Apnea in Individuals With Schizophrenia","authors":"Habibolah Khazaie, Siamand Mazhar, A. Moghadam, M. R. Ghadami, Sepideh Khazaie, A. Parvizifard","doi":"10.17241/smr.2022.01326","DOIUrl":"https://doi.org/10.17241/smr.2022.01326","url":null,"abstract":"Background and Objective Weight gain and obesity could be side effects of taking atypical antipsychotic medications. They are major risk factors for obstructive sleep apnea. The purpose of this study was to investigate effects of atypical antipsychotic medications on the risk of obstructive sleep apnea in individuals with schizophrenia and control groups.Methods In this cross-sectional study, 123 patients with schizophrenia and 107 participants were selected from hospital staff and students using purposive sampling. Data were collected using structured clinical interview and Berlin questionnaires.Results Results showed that the risk of obstructive sleep apnea was significantly higher in individuals with schizophrenia. Age, body mass index, and phases of schizophrenia showed meaningful relationships with the duration of taking atypical antipsychotic medications with the risk of obstructive sleep apnea. However, the type of atypical antipsychotic medications did not have a significant relationship with the risk of obstructive sleep apnea.Conclusions Patients with schizophrenia treated with atypical antipsychotic medicationshave a higher risk of obstructive sleep apnea.","PeriodicalId":37318,"journal":{"name":"Sleep Medicine Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45728601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

The Incidence of Renal Cell Carcinoma Is Increased in Patients With Obstructive Sleep Apnea 阻塞性睡眠呼吸暂停患者肾癌的发病率增加

Sleep Medicine Research Pub Date : 2022-09-30 DOI: 10.17241/smr.2022.01305

H. Park, W. Choi, J. Cho

引用次数: 0

The High-Dose of Exogenous Melatonin Did Not Alter the Sleep-Wake Cycle in Anoxic Brain Injury Patients 高剂量外源性褪黑素不会改变缺氧性脑损伤患者的睡眠-觉醒周期

Sleep Medicine Research Pub Date : 2022-09-30 DOI: 10.17241/smr.2022.01361

M. Kanarskii, J. Nekrasova, Pranil M. Pradhan, I. Borisov, O. Korepina, E. Kondratyeva, Angelina Nikitkina, Marina Petrova

{"title":"The High-Dose of Exogenous Melatonin Did Not Alter the Sleep-Wake Cycle in Anoxic Brain Injury Patients","authors":"M. Kanarskii, J. Nekrasova, Pranil M. Pradhan, I. Borisov, O. Korepina, E. Kondratyeva, Angelina Nikitkina, Marina Petrova","doi":"10.17241/smr.2022.01361","DOIUrl":"https://doi.org/10.17241/smr.2022.01361","url":null,"abstract":"Disturbance in circadian rhythms and the sleep-wake cycle is typical for patients in the intensive care unit, which retards rehabilitation. To assess the effect of exogenous melatonin and simultaneous mitigation of intensive care unit environmental factors on sleep duration. We studied five patients with chronic disorder of consciousness caused by anoxic brain injury. In addition, we varied the level of melatonin secretion in blood plasma to assess melatonin’s bioavailability and elimination time. We evaluated the sleep-wake cycle using continuous videoelectroencephalogram monitoring with the addition of oculographic and myographic channels for 72 hours. All the patients received melatonin tablets on the second day, wore masks and ear plugs, and had no feeding and nursing manipulations at night on the second and third days. There was no significant difference in sleep time between the first, second, and third days. Future studies of the circadian rhythm should aim at gaining a deeper analysis of the characteristics of the sleep-wake cycle in patients with severe anoxic brain injury together with further research for possible ways to influence the circadian component of sleep.","PeriodicalId":37318,"journal":{"name":"Sleep Medicine Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45877357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Postural Effect on Obstructive Sleep Apnea: Sitting Versus Supine 姿势对阻塞性睡眠呼吸暂停的影响:坐与仰卧

Sleep Medicine Research Pub Date : 2022-09-30 DOI: 10.17241/smr.2022.01312

K. Ji

引用次数: 0

The DBST Index, the Discrepancy Between Desired Time in Bed and Desired Total Sleep Time: The Possible New Sleep Index Predicting Severity of Insomnia DBST指数，期望卧床时间和期望总睡眠时间之间的差异:预测失眠严重程度的可能的新睡眠指数

Sleep Medicine Research Pub Date : 2022-09-30 DOI: 10.17241/smr.2022.01368

Seockhoon Chung

{"title":"The DBST Index, the Discrepancy Between Desired Time in Bed and Desired Total Sleep Time: The Possible New Sleep Index Predicting Severity of Insomnia","authors":"Seockhoon Chung","doi":"10.17241/smr.2022.01368","DOIUrl":"https://doi.org/10.17241/smr.2022.01368","url":null,"abstract":"Background and Objective We considered the concept of the DBST, the discrepancy between a patient’s desired time in bed (TIB) and desired total sleep time (TST). The DBST index can be used to easily assess a patient’s thoughts on their desired TST and dysfunctionally long TIB. This study aimed to explore whether the DBST index can predict the severity of insomnia.Methods A total of 374 members of the general population participated in this e-survey study. The participants answered questions regarding their bedtime, sleep onset time, wake-up time, desired TST, and desired TIB, and psychological symptoms were assessed using the Insomnia Severity Index (ISI), Patients Health Questionnaire–9 items (PHQ-9), Dysfunctional Beliefs and Attitudes about Sleep–16 items (DBAS-16), and Glasgow Sleep Effort Scale (GSES).Results The DBST index was significantly correlated with the ISI (r = 0.20, p < 0.01), PHQ-9 (r = 0.15, p < 0.01), GSES (r = 0.14, p < 0.01), DBAS-16 (r = 0.16, p < 0.01), desired TST (r = -0.62, p < 0.01), and desired TIB (r = 0.52, p < 0.01). Linear regression analysis showed that insomnia severity was predicted by persistent preoccupation with sleep (beta = 0.64, p < 0.001), dysfunctional beliefs about sleep (beta = 0.06, p < 0.001), depression (beta = 0.23, p < 0.001), and DBST (beta = 0.32, p = 0.035). The DBST directly influenced insomnia severity, and this association was shown to be mediated by dysfunctional beliefs and attitudes about sleep, preoccupation with sleep, and depression.Conclusions The DBST index could be a possible new sleep index due to its relationship with insomnia severity, depression, dysfunctional beliefs about sleep, and preoccupation with sleep. Further studies are needed to explore the consistency of the clinical sample.","PeriodicalId":37318,"journal":{"name":"Sleep Medicine Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45269919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Surgical Outcomes for Obstructive Sleep Apnea in Korea 韩国阻塞性睡眠呼吸暂停的手术结果

Sleep Medicine Research Pub Date : 2022-09-30 DOI: 10.17241/smr.2022.01424

Minkyeong Lee, Jae Yong Lee, J. Choi

{"title":"Surgical Outcomes for Obstructive Sleep Apnea in Korea","authors":"Minkyeong Lee, Jae Yong Lee, J. Choi","doi":"10.17241/smr.2022.01424","DOIUrl":"https://doi.org/10.17241/smr.2022.01424","url":null,"abstract":"Obstructive sleep apnea (OSA) is a common chronic sleep disorder that causes oxygen desaturations, sympathetic hyperactivation, and sleep fragmentation. The gold standard for OSA treatment in adults is positive airway pressure (PAP) therapy, which is effective when used during sleep. However, about half of patients with OSA refuse or are non-adherent to PAP, and some patients have anatomical problems that can be alleviated surgically. Surgery can be considered for patients who are very likely to have successful surgical results, but who are intolerant to PAP or oral appliances because of anatomical abnormalities. There are various surgical modifications of the upper airway for OSA, including nasal surgeries (e.g., septoplasty, turbinoplasty, and endoscopic sinus surgery), nasopharyngeal surgeries, oral and oropharyngeal surgeries (e.g., uvulopalatopharyngoplasty and variations, tonsillectomy, and palatal implants), hypopharyngeal surgeries (e.g., tongue ablation, tongue-base resection, and genioglossus advancement), and multi-level surgeries. Much clinical research has reported the outcomes of various surgical procedures for OSA internationally based on the traditional surgical success rate (defined as ≥ 50% reduction in the postoperative apnea-hypopnea index [AHI], postoperative AHI < 20), and AHI reduction ratio (defined as between the preoperative and postoperative AHI). In addition, many studies investigating the results of various OSA surgeries have been reported in Korea. In this article, we review the characteristics of various upper airway surgical procedures for OSA, global surgical results for OSA, and current surgical outcomes for OSA in Korea.","PeriodicalId":37318,"journal":{"name":"Sleep Medicine Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48413279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2