Journal of Experimental Orthopaedics最新文献

{"title":"The use of four K-wires does not lead to a reduction of the MPTA in the context of a one-dimensional tibial deflection correction of patients with ACL re-rupture and pathologically increased tibial slope","authors":"Christian Arras,&nbsp;Alexander Korthaus,&nbsp;Jannik Frings,&nbsp;Markus T. Berninger,&nbsp;Hendrik Fahlbusch,&nbsp;Karl-Heinz Frosch,&nbsp;Tobias Drenck,&nbsp;Ralph Akoto,&nbsp;Matthias Krause","doi":"10.1002/jeo2.70145","DOIUrl":"10.1002/jeo2.70145","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Purpose</h3>\u0000 \u0000 <p>Anterior tibial closing wedge osteotomy (ATCWO) has been shown to significantly reduce failure rates of revision anterior cruciate ligament (ACL) reconstructions in patients with a posterior tibial slope (PTS) ≥12°. Recent findings suggest a slight but significant reduction of the medial proximal tibial angle (MPTA) resulting in a varus knee where the sagittal osteotomy plane is based on a total of two guide wires defining the osteotomy wedge without respecting the frontal plane. We hypothesize that the placement of a total of four guide wires intraoperatively can reduce the influence on the MPTA.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This study retrospectively reports on a two-centre series of 42 ATCWOs for PTS correction between January 2022 and December 2023 at two clinical centres. A total of four guide wires were placed based on a true lateral intraoperative view of the tibia, with two positioned each at the cranial and at the caudal pole of the osteotomy wedge, serving as guides for the saw to create the osteotomy, with careful attention to ensuring that the proximal and distal K-Wires were placed parallel to each other. A retrospective analysis was conducted by examining true lateral and anteroposterior radiographs to identify changes in sagittal and coronal plane alignment.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The study included 19 women and 23 men, with a mean age of 29.7 ± 8.6 years with first-time ACL revision surgery and a minimum PTS of ≥12°. PTS decreased significantly from 14.5 ± 2.8° preoperatively to 8.2 ± 1.9° post-operatively (<i>p</i> &lt; 0.001). The aMPTA demonstrated no significant difference between preoperative (mean aMPTA: 86.9 ± 2.1°) and post-operative (mean aMPTA: 86.6 ± 1.9°) measurements (<i>p</i> &gt; 0.05).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>With our technique of placing four guide wires to achieve precise guidance during the insertion of the osteotomy wedge, there is no substantial impact on the aMPTA during slope correction.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Level of Evidence</h3>\u0000 \u0000 <p>Level IV.</p>\u0000 </section>\u0000 </div>","PeriodicalId":36909,"journal":{"name":"Journal of Experimental Orthopaedics","volume":"12 1","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11763354/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143047873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cartilage thickness can be accurately measured intraoperatively in total knee arthroplasty: A step further in calipered kinematic alignment","authors":"Giancarlo Giurazza,&nbsp;Stefano Campi,&nbsp;Michael T. Hirschmann,&nbsp;Edoardo Franceschetti,&nbsp;Andrea Tanzilli,&nbsp;Pietro Gregori,&nbsp;Michele Paciotti,&nbsp;Biagio Zampogna,&nbsp;Rocco Papalia","doi":"10.1002/jeo2.70155","DOIUrl":"10.1002/jeo2.70155","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Kinematic alignment (KA) in total knee arthroplasty (TKA) is by definition a pure femoral resurfacing procedure aiming to restore the individual prearthritic anatomy. However, when a 2 mm compensation is systematically used on the worn side, the variability in cartilage thickness in the unworn compartment might alter the accuracy of the technique. This study aimed to validate two intraoperative femoral cartilage thickness measurement techniques by comparing them to the photographic method, which measures cartilage thickness through pixel analysis of bone-cut images. The study hypothesized that the two intraoperative methods are comparable and similarly accurate within 0.5 mm of the photographic method.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Seventy cartilage thickness measurements from seventy patients with end-stage knee osteoarthritis were prospectively collected. Two intraoperative techniques were evaluated: the electrocautery tip method (Method A) and the ruler method (Method B), performed before and after distal femoral bone resections, respectively. The postoperative photographic analysis (Method C) served as the reference method. Measurements were rounded to the nearest 0.5 mm for consistency. Data were analyzed using Kruskal–Wallis test, Wilcoxon rank-sum tests, Spearman's rank correlation, percentage of agreement and intraclass correlation coefficients (ICCs).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>No significant differences were observed between Method A and Method B in measuring femoral cartilage thickness. Agreement with Method C was 100% for Method B and 85% for Method A. In the 15% of discordant cases, Method A overestimated the measurements by one category of 0.5 mm compared to Method C. Correlation coefficients between the methods were high (<i>ρ</i> = 0.88−1.0). Intra- and interobserver reliability was high for all methods (ICCs 0.91–0.95).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Discussion</h3>\u0000 \u0000 <p>Both intraoperative methods are reliable and comparable to the photographic method when rounded to the closest 0.5 mm, with no significant differences among them. The electrocautery method has the added advantage of measuring cartilage thickness before bone cuts are performed.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Level of Evidence</h3>\u0000 \u0000 <p>Level IV.</p>\u0000 </section>\u0000 </div>","PeriodicalId":36909,"journal":{"name":"Journal of Experimental Orthopaedics","volume":"12 1","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11763056/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143047940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical outcomes and biomechanics in bicruciate-retaining total knee arthroplasty","authors":"Kenichi Kono,&nbsp;Tomofumi Kage,&nbsp;Takaharu Yamazaki,&nbsp;Shuji Taketomi,&nbsp;Ryota Yamagami,&nbsp;Hiroshi Inui,&nbsp;Tetsuya Tomita,&nbsp;Sakae Tanaka","doi":"10.1002/jeo2.70152","DOIUrl":"10.1002/jeo2.70152","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Purpose</h3>\u0000 \u0000 <p>To clarify the influence of biomechanics on post-operative clinical outcomes in bicruciate-retaining total knee arthroplasty (BCR-TKA).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Severe medial osteoarthritis who underwent BCR-TKA were examined. Each patient was asked to perform a squat (weight-bearing [WB]) and active assisted knee flexion (non-WB [NWB]) under single fluoroscopy surveillance. A 2D-to-3D registration technique was used. Patients were divided into two groups based on their 1-year post-operative patient-reported outcome measures (PROMs) using hierarchical cluster analysis. The rotational alignment on computed tomography, anterior stability at 30° of knee flexion, axial rotation of the femur relative to the tibial component and anteroposterior translation of the medial and lateral femorotibial contact points were measured.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Components did not significantly differ between the groups, with 1.6 ± 5.0° and 5.4 ± 4.7° of femoral internal rotation in the low PROM (<i>N</i> = 28) and high PROM (<i>N</i> = 8) groups, respectively. Moreover, anterior stability did not significantly differ (low PROM: 4.9 ± 1.4 mm, high PROM: 5.3 ± 1.0 mm). The knee externally rotated from 0° to 70° and from 50° to 110° of flexion during WB and NWB, respectively. The low-PROM group exhibited more external rotation across all ranges of motion. Medial contact points moved backwards from 0° to 30° of flexion during WB, forward from 30° to 100° of flexion, and backwards from 100° to 110° of flexion. The low-PROM group was positioned more forward throughout the full range of motion during WB. Lateral contact points moved backwards at 0−30° of flexion, forward at 70−100° of flexion, and backwards at 100−110° of flexion during WB, while there was backward movement at 50° of flexion during NWB. Both activities exhibited a more posterior position in the low-PROM group throughout the full range of motion.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The femoral component in the low-PROM group was externally rotated across all ranges of motion, and the lateral contact points were posteriorly located in BCR-TKA.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Level of Evidence</h3>\u0000 \u0000 <p>Level II, prospective cohort study.</p>\u0000 </section>\u0000 </div>","PeriodicalId":36909,"journal":{"name":"Journal of Experimental Orthopaedics","volume":"12 1","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11763351/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143047854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biomechanical comparison of all-inside meniscal suture configurations for posterior root tear: Three conventional stitches versus delta-grip stitch","authors":"Kyohei Ishibashi,&nbsp;Kyota Ishibashi,&nbsp;Takahiro Tsushima,&nbsp;Eiji Sasaki,&nbsp;Shohei Yamauchi,&nbsp;Yuka Kimura,&nbsp;Yasuyuki Ishibashi","doi":"10.1002/jeo2.70149","DOIUrl":"10.1002/jeo2.70149","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Purpose</h3>\u0000 \u0000 <p>This study aimed to compare the biomechanical properties of four meniscal suture configurations—two simple sutures (TSS), two cinch sutures, a locking loop stitch (LLS), and a delta-grip stitch (DGS)—for transtibial pullout repair of medial meniscus posterior root tears (MMPRTs) using porcine menisci.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Forty porcine menisci were randomly assigned to each suture configuration with all-inside repair. All specimens were subjected to cyclic loading for 1000 cycles, followed by a load-to-failure test. We evaluated displacement after cyclic loading, the ultimate failure load and the mode of failure.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>No significant differences in displacement were observed between the configurations (<i>p</i> = 0.709). The DGS exhibited significantly higher ultimate failure loads (281.4 ± 53.5 N) compared to TSS (166.8 ± 84.5 N) and the LLS (119.7 ± 46.7 N) (<i>p</i> = 0.006 and <i>p</i> &lt; 0.001, respectively). Suture breakage was observed in the DGS group, while meniscus cutout was observed in the other suture configuration models.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The results suggest that the DGS provides superior fixation strength and enhances MMPRT repair outcomes.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Level of Evidence</h3>\u0000 \u0000 <p>Level IV.</p>\u0000 </section>\u0000 </div>","PeriodicalId":36909,"journal":{"name":"Journal of Experimental Orthopaedics","volume":"12 1","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11751621/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143025115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Functional outcome improvement and surgical time reduction in a single-surgeon consecutive case series of hip arthroscopy for femoroacetabular impingement: A minimum 5 years follow-up study","authors":"Enrico Tassinari,&nbsp;Filippo Caternicchia,&nbsp;Mattia D. Rosa,&nbsp;Francesco Castagnini,&nbsp;Edoardo Angeletti,&nbsp;Valentina Fantoni,&nbsp;Irene Tampieri,&nbsp;Andrea Burla,&nbsp;Stefano Zaffagnini","doi":"10.1002/jeo2.70022","DOIUrl":"10.1002/jeo2.70022","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Purpose</h3>\u0000 \u0000 <p>The learning curve of a single surgeon performing hip arthroscopy is reported to be steep, but, to date, the inflection point after which procedures are more successful is still unknown. The aim of this study was to design a learning curve focused on clinical outcomes, complications and revision/conversion rates.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Seventy-one hip arthroscopies performed for femoroacetabular impingement (FAI) by a single surgeon, with a minimum follow-up of 5 years, were considered. Demographics, intraarticular findings and operative and traction time were detailed. HOOS score, subjective outcomes, 30-day complication rates, complication rates, revision arthroscopies and conversions to hip arthroplasty were recorded.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The mean follow-up was 7.5 ± 1.8 years (range: 5–11). The progression of the learning curve implied a reduction in surgical time (<i>r</i>: −0.847), traction time (<i>r</i>: −0.806) and postoperative outcomes (<i>r</i> = 0.444). When the procedures were divided into three consecutive groups (25 vs. 25 vs. 21 procedures) or two consecutive groups (36 vs. 35 cases), the first group had a higher occurrence of 30-day complications (<i>p</i> = 0.002 and <i>p</i> = 0.025, respectively) and the last group experienced a significant amelioration in terms of HOOS score between the preoperative and the postoperative condition (<i>p</i> &lt; 0.001 and <i>p</i> = 0.018).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The inflection point of the hip arthroscopy learning curve is between 25/36 procedures. The first arthroscopies were impacted by higher complications and lower clinical results but no higher rates of revision and conversion to arthroplasty.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Level of Evidence</h3>\u0000 \u0000 <p>Level IV.</p>\u0000 </section>\u0000 </div>","PeriodicalId":36909,"journal":{"name":"Journal of Experimental Orthopaedics","volume":"12 1","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11751622/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143025136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of four sterilization techniques for meniscal allograft transplantation in rabbits","authors":"X. S. Wang,&nbsp;H. G. Jia,&nbsp;D. Q. Gu,&nbsp;D. Z. Luo,&nbsp;Y. T. Zhao,&nbsp;Z. J. Liu,&nbsp;Y. D. Zhang","doi":"10.1002/jeo2.70150","DOIUrl":"10.1002/jeo2.70150","url":null,"abstract":"&lt;div&gt;\u0000 \u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Purpose&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;This study aimed to compare the effects of four sterilization techniques on meniscal allograft transplantation (MAT) in rabbits.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Methods&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;In total, 85 medial or lateral meniscuses were obtained from 22 adult New Zealand white rabbits. These 85 meniscal allografts were seeded with &lt;i&gt;Staphylococcus aureus&lt;/i&gt; (&lt;i&gt;S. aureus&lt;/i&gt;) and randomly divided into five groups (&lt;i&gt;n &lt;/i&gt;= 17): iodine group, Cobalt-60 group, glutaraldehyde group, ethylene oxide group and control group. Bacterial colonies of the allografts were determined before (&lt;i&gt;n&lt;/i&gt; = 7) and after (&lt;i&gt;n&lt;/i&gt; = 7) sterilization. Histological features were analyzed using haematoxylin and eosin (H&amp;E) staining (&lt;i&gt;n&lt;/i&gt; = 3). An additional 50 medial or lateral meniscuses were taken from 13 adult New Zealand white rabbits, and they were kept fresh-frozen (−40°C) for 1 month. Subsequently, these 50 meniscuses were randomly divided into five groups, which were treated with iodine, Cobalt-60, glutaraldehyde, ethylene oxide and normal saline, separately (&lt;i&gt;n&lt;/i&gt; = 10), and stored at −20°C before MAT. MAT was given to the knee joints of the right hind legs of 50 adult Japanese white rabbits. After 6 weeks of MAT, the transplanted meniscal allografts were taken for biomechanical test (&lt;i&gt;n&lt;/i&gt; = 7) and H&amp;E staining (&lt;i&gt;n&lt;/i&gt; = 3).&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Results&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;The results of the bacterial count indicated that the number of &lt;i&gt;S. aureus&lt;/i&gt; colonies was less than 1 colony-forming unit (CFU)/allograft in all five groups after sterilization, except for the control group (415 CFU/allograft). H&amp;E staining revealed that allografts in the iodine group presented the complete structure; allografts in the Cobalt-60 and glutaraldehyde groups were preserved relatively well; and allografts in the control and ethylene oxide groups were severely destructed, especially in the ethylene oxide group. Using the transplanted allografts, the biomechanical test showed that the maximum load of allografts in each group was significantly different, with ethylene oxide effective sterilization agents being used for disinfecting meniscal grafts (iodine group: 270.71 ± 62.81 N, Cobalt-60 group: 182.14 ± 71.29 N, glutaraldehyde group: 254.29 ± 31.55 N, ethylene oxide group: 40.00 ± 22.73 N and control group: 183.14 ± 76.40) (&lt;i&gt;p&lt;/i&gt; ≤ 0.001). H&amp;E staining with transplanted allografts revealed that allografts in the iodine group had the most intact structure; allografts in the Cobalt-60 and glutaraldehyde groups presented a relatively intact structure; and allografts in the control and ethylene oxide groups were seriously damag","PeriodicalId":36909,"journal":{"name":"Journal of Experimental Orthopaedics","volume":"12 1","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11746939/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143013335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"3D-printed patient-specific instrumentation and the freehand technique in high-tibial osteotomy: A prospective cohort-comparative study in an outpatient setting","authors":"Giovanni Grillo,&nbsp;Alexandre Coelho,&nbsp;Xavier Pelfort,&nbsp;Ferran Fillat-Gomà,&nbsp;Arnau Verdaguer Figuerola,&nbsp;Sergi Gil-Gonzalez,&nbsp;Juan Manuel Peñalver,&nbsp;Christian Yela-Verdú","doi":"10.1002/jeo2.70088","DOIUrl":"10.1002/jeo2.70088","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Purpose</h3>\u0000 \u0000 <p>Tibial valgus osteotomy has shown to be a successful and cost-effective procedure. The advent of image processing and three-dimensional (3D) printing is an interesting tool for achieving more accurate and reproducible results. The aim of our study was to compare the accuracy of the conventional technique and the use of customized guides in the correction of tibial deformities in tibial varus patients, the surgical and clinical benefits, and the impact of treatment in the outpatient setting.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A prospective cohort of 30 patients who underwent tibial valgus osteotomy were selected and randomized into two groups (3D-printed guidewires and conventional techniques). All patients underwent a complete radiological study to plan the surgical procedure. During the surgical procedure, the surgical time and X-ray exposure were analysed. The following results were evaluated: surgical time and X-ray exposure, the correlation between the planned correction and the correction obtained at 3 post-operative months, pre- and post-operative knee injury and osteoarthritis outcome score (KOOS) value at 3 and 12 months, and differences between the two groups in terms of the correction obtained.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Radiation exposure in the ‘3D-guide’ group was significantly different (8 [±4.51], <i>p</i> &lt; 0.05), whereas surgical time was not significantly different between the control and guide 3D groups (60.69 [±8.89] and 53.43 [±11.69], respectively). At the 3-month follow-up, the post-operative hip–knee–ankle and post-operative mechanical–proximal–tibial angle were not significantly different (<i>p</i> &gt; 0.05). At 3- and 12-month post-surgery, the Knee Injury and Osteoarthritis Outcome Score (KOOS) did not significantly differ between the conventional technique and the 3D-guide technique (<i>p</i> &gt; 0.05). The KOOS at 3 months were 87.86 (±5.64) for the control group and 88.46 (±3.53) for the 3D-guide group, while at 12 months they were 91.5 (±5.72) for the control group and 88.57 (±8.81) for the 3D-guide group.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Customized 3D-printed guides do not permit better correction or functional results than the conventional technique; rather, they reduce surgical time and intraoperative radiation exposure.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Level of Evidence</h3>\u0000 \u0000 <p>II.</p>\u0000 </section>\u0000 </div>","PeriodicalId":36909,"journal":{"name":"Journal of Experimental Orthopaedics","volume":"12 1","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11747140/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143013317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The use of lateral wedge insoles delays osteoarthritis progression and improves clinical outcomes in medial meniscus posterior root repair","authors":"Koki Kawada,&nbsp;Yusuke Yokoyama,&nbsp;Yuki Okazaki,&nbsp;Masanori Tamura,&nbsp;Toshifumi Ozaki,&nbsp;Takayuki Furumatsu","doi":"10.1002/jeo2.70141","DOIUrl":"10.1002/jeo2.70141","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Purpose</h3>\u0000 \u0000 <p>The purpose of this retrospective study was to evaluate the efficacy of using a lateral wedge insole (LWI) during the first 3 months after medial meniscus posterior root (MMPR) repair.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Overall, 179 patients were categorized into LWI use (LWI group, 90 patients) and nonuse (control group, 89 patients) groups. Patients in the LWI group were instructed to wear an LWI from the initiation of load bearing up to 3 months postoperatively. Medial meniscus extrusion (MME) was evaluated preoperatively and 1 year postoperatively, Kellgren–Lawrence (KL) grade and clinical scores were evaluated preoperatively and 2 years postoperatively, and second-look arthroscopic meniscal healing scores were evaluated at 1 year postoperatively.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The proportion of patients with KL grade progression at 2 years postoperatively was significantly lower in the LWI group than in the control group (23.3% vs. 39.3%; <i>p</i> = 0.024). Change in the MME at 1 year postoperatively was significantly smaller in the LWI group than in the control group (1.1 ± 1.2 vs. 1.6 ± 1.4 mm; <i>p</i> = 0.042). The Lysholm score (<i>p</i> = 0.003) and Knee Injury and Osteoarthritis Outcome Scores-sport and recreation function (<i>p</i> = 0.027) at 2 years postoperatively were significantly superior in the LWI group than in the control group. The arthroscopic meniscal healing score after 1 year was not significantly different between the LWI and control groups (total score, 7.6 ± 1.1 vs. 7.4 ± 1.3 points; <i>p</i> = 0.732). The anteroposterior width of the repaired posterior root at 1 year second-look evaluation was significantly broader in the LWI group than in the control group (7.7 ± 1.6 vs. 6.9 ± 1.6 mm; <i>p </i>= 0.001).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The use of LWI is an effective way to delay postoperative osteoarthritis progression and improve clinical outcomes after MMPR repair.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Level of Evidence</h3>\u0000 \u0000 <p>Level III.</p>\u0000 </section>\u0000 </div>","PeriodicalId":36909,"journal":{"name":"Journal of Experimental Orthopaedics","volume":"12 1","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11747139/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143013386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Coronal alignment does not enable to predict the degree of femoral and tibial torsion","authors":"Leonard Grünwald,&nbsp;Sophie Schmidt,&nbsp;Marc-Daniel Ahrend,&nbsp;Tina Histing,&nbsp;Stefan Döbele","doi":"10.1002/jeo2.70073","DOIUrl":"10.1002/jeo2.70073","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Purpose</h3>\u0000 \u0000 <p>Malalignment of the lower extremity can affect one, two or all three anatomic planes. We hypothesized an influence between the malalignment of the coronal and axial planes.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A total of 356 lower extremities of 226 patients were included. Femoral and tibial torsion were assessed in computer tomographic scans while frontal plane alignment was measured in long-leg standing radiographs. The mechanical angles were for knee phenotyping according to the coronal plane alignment of the knee classification. The correlation between the coronal alignment and torsional profile was analyzed. The population was divided into three groups according to leg alignment (valgus, neutral, varus) and gender.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>As the coronal alignment changed from valgus to varus the tibial external torsion increased (<i>r</i> = 0.35; <i>p</i> &lt; 0.001). Femoral internal torsion increased as well but only in the male subgroup (<i>r</i> = −0.34; <i>p</i> &lt; 0.001). Both femoral internal torsion and tibial external torsion increased with higher mechanical lateral distal femoral angle (mLDFA) but were not related to mechanical medial proximal tibial angle. A distinct pattern of results concerning knee phenotypes in relation to femoral and tibial torsion was found.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Tibial torsion correlated with increasing varus alignment while both femoral and tibial torsion correlated with higher mLDFA, but the correlations were weak. Therefore, the coronal alignment does not enable to predict the degree of femoral and tibial torsion. This study demonstrates that an individual approach to each patient with lower limb malalignment is unavoidable.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Level of Evidence</h3>\u0000 \u0000 <p>Level III.</p>\u0000 </section>\u0000 </div>","PeriodicalId":36909,"journal":{"name":"Journal of Experimental Orthopaedics","volume":"12 1","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11747137/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143013285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Arthroscopic debridement followed by intra-articular injection of micro-fragmented adipose tissue in patients affected by knee osteoarthritis: Clinical results up to 48 months from a prospective clinical study","authors":"Andrea Antonio Maria Bruno,&nbsp;Giuseppe Anzillotti,&nbsp;Massimo De Donato,&nbsp;Marco Basso,&nbsp;Jacopo Tamini,&nbsp;Paolo Dupplicato,&nbsp;Elizaveta Kon,&nbsp;Berardo Di Matteo,&nbsp;Enrico Arnaldi","doi":"10.1002/jeo2.70144","DOIUrl":"10.1002/jeo2.70144","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Purpose</h3>\u0000 \u0000 <p>Micro-fragmented adipose tissue is emerging as a promising option for the treatment of various diseases including knee osteoarthritis (OA), though clinical trials are often limited by short follow-up periods. Our aim was to evaluate the safety and clinical outcomes of an arthroscopic debridement followed by a single injection of micro-fragmented adipose tissue in patients affected by knee OA.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>From 2016 to 2020, patients affected by knee OA were enroled. Micro-fragmented adipose tissue was obtained through the Lipogems® kit and intraarticularly injected after an arthroscopic debridement. Visual analogue scale for pain, Tegner score, Knee Injury and Osteoarthritis Outcome score subscales variations were assessed from baseline to 3, 6, 12, 24 and 48 months of follow-up.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Forty-one patients were evaluated up to 6 months of follow-up, 39 patients up to 24 months of follow-up and 38 patients up to 48 months of follow-up. Three underwent knee replacement surgery during the time of the study. All the clinical scores analyzed achieved statistically significant changes up to the last follow-up.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>A single intra-articular knee injection of micro-fragmented adipose tissue following arthroscopic debridement is able to provide significant clinical benefits in patients affected by knee OA up to 4 years of follow-up.</p>\u0000 \u0000 <p>The present clinical study was registered on clinicaltrials.gov (no. NCT06545266).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Level of Evidence</h3>\u0000 \u0000 <p>Level IV case series.</p>\u0000 </section>\u0000 </div>","PeriodicalId":36909,"journal":{"name":"Journal of Experimental Orthopaedics","volume":"12 1","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11739897/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143013323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}