Global Journal of Health Sciences and Research最新文献

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Impact of COVID-19 pandemic among healthcare professionals COVID-19 大流行对医护人员的影响
Global Journal of Health Sciences and Research Pub Date : 2023-12-16 DOI: 10.25259/gjhsr_51_2023
Jessy Abraham, Maria Therese
{"title":"Impact of COVID-19 pandemic among healthcare professionals","authors":"Jessy Abraham, Maria Therese","doi":"10.25259/gjhsr_51_2023","DOIUrl":"https://doi.org/10.25259/gjhsr_51_2023","url":null,"abstract":"\u0000\u0000The objectives of the study were to assess the impact of Covid-19 pandemic among healthcare professionals, to compare the level of impact of Covid-19 pandemic among different healthcare professionals, and to find the association of impact of Covid-19 pandemic with the selected demographic variables of the healthcare professionals with selected demographic variables.\u0000\u0000\u0000\u0000The research approach used was quantitative and research design adopted for the study was descriptive research design. A sample of 60 healthcare professionals was selected by stratified random sampling and the data were collected using questionnaire. The data collected were tabulated and analyzed using descriptive statistics.\u0000\u0000\u0000\u0000The result of our study showed that 5% of the healthcare professionals were mildly affected, 48.3% of healthcare professionals were moderately affected, and 46.7% of healthcare professionals were severely affected. There was no significant difference found between the levels of impact among different healthcare professionals. There is a significant association between the level of impact of Covid-19 and the type of family.\u0000\u0000\u0000\u0000Study found that Covid-19 had an impact on healthcare professionals.\u0000","PeriodicalId":369069,"journal":{"name":"Global Journal of Health Sciences and Research","volume":"62 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138967829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Eating behavior of early adults: A cross-sectional analysis 早期成年人的饮食行为:横截面分析
Global Journal of Health Sciences and Research Pub Date : 2023-12-14 DOI: 10.25259/gjhsr_28_2023
Swetha P S, P. B. Jos
{"title":"Eating behavior of early adults: A cross-sectional analysis","authors":"Swetha P S, P. B. Jos","doi":"10.25259/gjhsr_28_2023","DOIUrl":"https://doi.org/10.25259/gjhsr_28_2023","url":null,"abstract":"\u0000\u0000The present study aims to find out the relationship between the three types of eating behavior with emotional intelligence (EI), Big Five personality traits, and frustration intolerance of early adults using online food delivery system.\u0000\u0000\u0000\u0000A sample size of 258 was collected using the technique of convenient sampling. This cross-sectional research employs Spearman’s Rank correlation and Mann–Whitney U-test for data analysis.\u0000\u0000\u0000\u0000There is negative relationship between emotional eating (EE) and EI, there is negative relationship between cognitive restraint (CR) eating and extraversion, there is negative relationship between uncontrolled eating (UE) and conscientiousness, there is positive relationship between EE and openness, there is positive relationship between CR eating and emotional intolerance (EIn), there is positive correlation between UE and entitlement, there is positive correlation between EE and discomfort intolerance, there is significant difference in the openness, agreeableness, and neuroticism of males and females using online food delivery system, and there is significant difference in the EIn of females and males using online food delivery system.\u0000\u0000\u0000\u0000The study emphasizes the relevance of healthy eating behavior in early adults for maintaining their mental health.\u0000","PeriodicalId":369069,"journal":{"name":"Global Journal of Health Sciences and Research","volume":"3 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139001142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of azithromycin administration in cases of acute bronchiolitis – A systematic review and meta-analysis 阿奇霉素给药对急性细支气管炎的影响——一项系统回顾和荟萃分析
Global Journal of Health Sciences and Research Pub Date : 2023-09-20 DOI: 10.25259/gjhsr_60_2023
Preethi Tamilarasan, Kanimozhi Thandapani, J. Jenifer Florence Mary, Reenaa Mohan, Kalaiselvan Ganapathy
{"title":"Effect of azithromycin administration in cases of acute bronchiolitis – A systematic review and meta-analysis","authors":"Preethi Tamilarasan, Kanimozhi Thandapani, J. Jenifer Florence Mary, Reenaa Mohan, Kalaiselvan Ganapathy","doi":"10.25259/gjhsr_60_2023","DOIUrl":"https://doi.org/10.25259/gjhsr_60_2023","url":null,"abstract":"Acute Bronchiolitis is the most common viral lower respiratory tract infection in infants requiring hospitalization. Management is usually symptomatic and supportive with no specific treatment options. Although viral, Azithromycin by its anti-inflammatory properties might play a role in improving the clinical outcome. The objective was to assess the effect of azithromycin on length of hospital stay and duration of oxygen requirement in cases of acute bronchiolitis. Data sources such as PubMed and Google Scholar were systematically searched till June 2023. The meta-analysis included all published, randomized controlled trials that investigated the efficacy of Azithromycin over placebo in infants <24 months with acute bronchiolitis. Data extraction was guided by a predetermined checklist. Using RevMan 5 software, the mean length of hospital stay and duration of oxygen administration were pooled from the selected studies. The fixed-effect model was used to compare the length of hospital stay and the duration of oxygen administration in the Azithromycin and placebo group. Data analyses were performed in July 2023. The primary outcome was a comparison of the length of hospital stay in infants with Bronchiolitis receiving either azithromycin (intervention) or placebo (control). The secondary outcome was the assessment of the duration of oxygen requirement in both intervention and control groups.The initial search yielded 601 records of which 68 articles underwent full-text evaluation, which identified four articles and a total of 571 patients that were included. The findings did not favor the usage of azithromycin antibiotic in treatment of acute bronchiolitis (Mean deviation = 1.21, 95% CI 0.53–2.78, P = 0.80). An insignificant Q statistic ( P = 0.001) indicated the absence of heterogeneity (I2 = 0%). Length of hospital stay showed an overall insignificant effect as the length of stay is almost similar in both drugs (OR = 1.04 95% CI 0.49–2.23, P = 1.00). An insignificant Q statistic ( P = 1.00) indicated the absence of heterogeneity (I2 = 0%).","PeriodicalId":369069,"journal":{"name":"Global Journal of Health Sciences and Research","volume":"71 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136309597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neutrophil-lymphocyte ratio among preeclampsia patients in India – A systematic review and meta-analysis 中性粒细胞-淋巴细胞比率在印度子痫前期患者-系统回顾和荟萃分析
Global Journal of Health Sciences and Research Pub Date : 2023-09-20 DOI: 10.25259/gjhsr_59_2023
Deepika Velusami, Krishnamurthy Soundariya, Reena Mohan, J. Jenifer Florence Mary, Kalaiselvan Ganapathy, P. Sanjay
{"title":"Neutrophil-lymphocyte ratio among preeclampsia patients in India – A systematic review and meta-analysis","authors":"Deepika Velusami, Krishnamurthy Soundariya, Reena Mohan, J. Jenifer Florence Mary, Kalaiselvan Ganapathy, P. Sanjay","doi":"10.25259/gjhsr_59_2023","DOIUrl":"https://doi.org/10.25259/gjhsr_59_2023","url":null,"abstract":"Preeclampsia is one of the major causes of morbidity and mortality in pregnant females in India. Early detection of preeclampsia can be of clinical utility. Neutrophil Lymphocyte Ratio (NLR) is a simple hepatological biomarker that has been used for diagnosis of preeclampsia. With this perspective in mind, the present meta-analysis was planned to evaluate NLR among preeclampsia in the Indian setting. Databases systematically searched were PubMed, MEDLINE, and Google Scholar were systematically searched till July 2023. The studies selected were all Indian published articles NLR evaluated in females of age ≥18 years and < 40 years with preeclampsia and normal health pregnant females. Data extraction was guided by a predetermined checklist. Using RevMan 5 software, the mean and standard deviation were evaluated and analyzed. The initial search yielded 103 records of which 54 articles underwent evaluation, which identified 8 articles and a total 1381 study population. Of these, 534 cases of preeclampsia and 847 normal healthy pregnant females investigated the significance of evaluation of NLR for identification of preeclampsia. The meta-analysis showed an overall significant effect in favor of the importance of NLR investigation in predicting preeclampsia (SMR = 1.04, 95% CI 0.91–1.16, p < 0.001). A significant Q statistic (p < 0.001) indicated the presence of heterogeneity (I2 = 96%). This systematic review and meta-analysis proved that NLR can be employed for detecting early preeclampsia. Further prospective studies are needed to validate the potential applicability of NLR as a diagnostic marker in clinical setup.","PeriodicalId":369069,"journal":{"name":"Global Journal of Health Sciences and Research","volume":"145 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136313243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unkindest cut of all... unnecessary hysterectomy 最无情的切割……不必要的子宫切除术
Global Journal of Health Sciences and Research Pub Date : 2023-09-20 DOI: 10.25259/gjhsr_64_2023
A. Bupathy
{"title":"Unkindest cut of all... unnecessary hysterectomy","authors":"A. Bupathy","doi":"10.25259/gjhsr_64_2023","DOIUrl":"https://doi.org/10.25259/gjhsr_64_2023","url":null,"abstract":"","PeriodicalId":369069,"journal":{"name":"Global Journal of Health Sciences and Research","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136313771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Awareness, knowledge, and practice of performance status scale in the management of head and neck cancer patients among health-care providers in Edo state, Nigeria 尼日利亚埃多州卫生保健提供者在头颈癌患者管理中对绩效状况量表的认识、知识和实践
Global Journal of Health Sciences and Research Pub Date : 2023-08-09 DOI: 10.25259/gjhsr_10_2023
E. Edetanlen, O. Babalola
{"title":"Awareness, knowledge, and practice of performance status scale in the management of head and neck cancer patients among health-care providers in Edo state, Nigeria","authors":"E. Edetanlen, O. Babalola","doi":"10.25259/gjhsr_10_2023","DOIUrl":"https://doi.org/10.25259/gjhsr_10_2023","url":null,"abstract":"\u0000\u0000The roles of performance status scales (PSSs) are well-documented globally and is largely, routinely, and traditionally used in the management of cancer patients in the developed countries, but this is not true in developing countries, reason largely due to lack of awareness. Therefore, the present study aimed to assess the level of awareness, knowledge, and practice of PSSs among medical practitioners in Edo state Nigeria.\u0000\u0000\u0000\u0000This descriptive cross-sectional study design recruited all medical practitioners that managed head and neck cancers (HNCs) (Family Dental Physicians, Otolaryngologist and Oral and Maxillofacial Surgeons) in Edo state between April 2019 and December 2019. Data were obtained using a self-administered questionnaire which was given to all the participants that gave written informed consent. The statistical analysis was done using the Statistical Package for the Social Sciences version 21 (IBM, Chicago, Illinois, USA).\u0000\u0000\u0000\u0000One hundred and six of the 110 randomly distributed questionnaires were retrieved, given a response rate of 96.4%. The male-to-female ratio was 2.4:1.0. The mean age was 33.3 ± 5.30 years, ranging from 25 to 46 years. Most of the respondents were within the age range of 31–40 years, while the least numbers were over 40 years. Of the total 106 respondents, less than half (46.2%) had heard of PSS. More than two-third (73.6%) of the respondents had a general poor knowledge as regard PSS. More than half (53.8%) of the respondents answered that they have never used PSS in the course of managing HNC patient. The age, gender, years of practice, type of specialty, and location of practice were not related to the knowledge of PSS by the respondents (P > 0.05). There was a significant association between awareness of PSS before this study and the knowledge of PSS among the respondents (P = 0.02).\u0000\u0000\u0000\u0000Most Medical Practitioners that manage head and neck cancer patients lack awareness and knowledge of PSSs and hence poorly utilized in the management of patients in routine practice.\u0000","PeriodicalId":369069,"journal":{"name":"Global Journal of Health Sciences and Research","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124831985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of the lunar cycle on mental illness – A single-center retrospective observational study 月亮周期对精神疾病的影响-一项单中心回顾性观察研究
Global Journal of Health Sciences and Research Pub Date : 2023-08-09 DOI: 10.25259/gjhsr_39_2023
Sriramadesigan Radhakrishnan, A. Selvaraj, Perarul Sivakumar, Vasanth Kulothungan, Preethi Sathiyamoorthy
{"title":"Effect of the lunar cycle on mental illness – A single-center retrospective observational study","authors":"Sriramadesigan Radhakrishnan, A. Selvaraj, Perarul Sivakumar, Vasanth Kulothungan, Preethi Sathiyamoorthy","doi":"10.25259/gjhsr_39_2023","DOIUrl":"https://doi.org/10.25259/gjhsr_39_2023","url":null,"abstract":"\u0000\u0000In Shakespeare’s play “Othello,” the maid Emilia tells Othello that the moon has drawn too close to the Earth — and driven men insane. The notion that a full moon can elicit strong emotions, strange behavior, and even physical disease is not merely literary. Even now, it is a deeply held notion. The goal of this study was to determine the effect of the lunar cycle on the psychiatric presentation of individuals with schizophrenia, BPAD mania, and ATPD.\u0000\u0000\u0000\u0000Case files of Schizophrenia, bipolar affective disorder (BPAD) mania and psychosis patients admitted in our hospital during full moon and new moon ± 3 days for the past 5 years will be included in the study. Name, age, sex, duration of admission, worsening of symptoms during full moon day and new moon day, any injectable given or not will be noted. These data will be collected from medical records. Telephonic verification of symptom worseness during full moon and new moon will be done.\u0000\u0000\u0000\u0000Among 207 participants 74 patients had Schizophrenia, 91 patients had BPAD mania, 25 patients had ATPD and 17 patients had acute psychosis. The exacerbation of psychiatric symptoms, chemical restraints, and admission during phases of moon was statistically associated with lunar patterns in the study population. The rest of the socio-demographic factors, duration of admission, caregiver belief, and symptom worsening noted by caregiver were all not associated with mental illness during lunar phases which is in line with most reported literature in this area.\u0000\u0000\u0000\u0000There was an association between symptom exacerbations, chemical restraints, admission with different lunar phase. There was no association for sociodemographic details, duration of admission, caregiver belief on symptom worsening, symptom worsening noted by caregiver with different lunar phases.\u0000","PeriodicalId":369069,"journal":{"name":"Global Journal of Health Sciences and Research","volume":"153 ","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114057745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clenching exercise as additional orthodontic treatment in anterior open bite patients 握拳运动作为前牙开咬患者的辅助正畸治疗
Global Journal of Health Sciences and Research Pub Date : 2023-08-09 DOI: 10.25259/gjhsr_27_2023
Anis Irmawati, Maria Devitha, Noor Faizah Balqis, Yassir Ahmad Azzaim, Raed Al-Mekhlafi
{"title":"Clenching exercise as additional orthodontic treatment in anterior open bite patients","authors":"Anis Irmawati, Maria Devitha, Noor Faizah Balqis, Yassir Ahmad Azzaim, Raed Al-Mekhlafi","doi":"10.25259/gjhsr_27_2023","DOIUrl":"https://doi.org/10.25259/gjhsr_27_2023","url":null,"abstract":"\u0000\u0000Anterior open bite is a complex case of malocclusion that needs complex treatment. This malocclusion has a tendency to relapse, so the difficulty level of treatment is high. Clenching exercise began to be applied as an additional myofunctional therapy that can help correct anterior open bite and stabilize treatment results.\u0000\u0000\u0000\u0000This narrative review aims to explain clenching exercise as an additional orthodontic treatment in anterior open bite patients.\u0000\u0000\u0000\u0000The most essential step in open bite treatment is the retention period because the tendency for relapse is strong and difficult to predict. Surgical treatment can be used to achieve an anterior open bite, but this treatment does not guarantee the stability of the treatment outcome. To achieve retention in anterior open bite correction, it is essential to improve muscle function after treatment.\u0000\u0000\u0000\u0000Clenching exercise can be an additional therapy in anterior open bite patients to shorten the treatment duration and maintain the stability of the treatment outcome.\u0000","PeriodicalId":369069,"journal":{"name":"Global Journal of Health Sciences and Research","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120936135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
T1 contrast versus fluid-attenuated inversion recovery contrast technique for evaluation of cerebral tuberculosis T1对比液体衰减反转恢复对比技术评价脑结核
Global Journal of Health Sciences and Research Pub Date : 2023-08-09 DOI: 10.25259/gjhsr_15_2022
Balavaitheeswar Ramalingam, Elamparidhi Padmanaban, J. V. Raj, Pugazhendhi Sambath, Avinesh Varadane
{"title":"T1 contrast versus fluid-attenuated inversion recovery contrast technique for evaluation of cerebral tuberculosis","authors":"Balavaitheeswar Ramalingam, Elamparidhi Padmanaban, J. V. Raj, Pugazhendhi Sambath, Avinesh Varadane","doi":"10.25259/gjhsr_15_2022","DOIUrl":"https://doi.org/10.25259/gjhsr_15_2022","url":null,"abstract":"\u0000\u0000T2-weighted (T2W) fluid-attenuated inversion recovery (FLAIR), a traditional magnetic resonance imaging (MRI) technique, is regarded as one of the most effective methods for examining brain disorders. The identification of brain pathologies can be significantly aided by T2 FLAIR and T1 post-contrast imaging. However, lesion enhancement is occasionally inconspicuous on T1-weighted image. Hence, for the evaluation of brain disorders, a MRI approach known as FLAIR contrast would combine the benefits of T2W FLAIR with contrast-enhancement on a single picture.\u0000\u0000\u0000\u0000After obtaining clearance from the Institution’s Ethics Committee, contrast-enhanced MRI (CE-MRI) brain of 20 patients was taken for the study. CE-MRI was performed using 1.5 Tesla Intera PHILIPS with intravenous administration of gadolinium at approximately 0.1 mL/kg/body at a rate of 10 mL/15 s.\u0000\u0000\u0000\u0000This study showed a better appreciation of lesion conspicuity when compared to prior T1 contrast images. However, there was no significant difference in the number of lesions, lesion extension, and degree of contrast-enhancement on comparison with T1 contrast images.\u0000\u0000\u0000\u0000T1 FLAIR contrast shows a better appreciation of lesion conspicuity when compared to T1 contrast images. Post-contrast FLAIR imaging is a valuable adjunct to post-contrast T1W imaging and effectively delineates cerebral tubercular pathologies. However, T1 FLAIR cannot be used as a replacement for conventional T1 fat saturated post-contrast imaging.\u0000","PeriodicalId":369069,"journal":{"name":"Global Journal of Health Sciences and Research","volume":"71 5","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121015387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effect of paracetamol on the parasitological diagnosis of Plasmodium falciparum malaria 对乙酰氨基酚在恶性疟原虫疟疾寄生虫学诊断中的作用
Global Journal of Health Sciences and Research Pub Date : 2023-08-09 DOI: 10.25259/gjhsr_9_2023
Mohamed Magzob, Ashraf Al Sammani, Ahmed Al Siddiq
{"title":"The effect of paracetamol on the parasitological diagnosis of Plasmodium falciparum malaria","authors":"Mohamed Magzob, Ashraf Al Sammani, Ahmed Al Siddiq","doi":"10.25259/gjhsr_9_2023","DOIUrl":"https://doi.org/10.25259/gjhsr_9_2023","url":null,"abstract":"\u0000\u0000Up until the present time, malaria represents an immense public health problem worldwide with a significant morbidity and mortality rate in many developing countries including Sudan. The use of antipyretics and analgesics in the settings of malaria has been a matter of contention over a vast period of time. Now, it is widely believed among the public and some health professionals in Sudan that the antipyretic and analgesic paracetamol disturbs the accuracy of the parasitological diagnosis of malaria. This study investigates the magnitude and effects of that belief through a descriptive study and examines the actual effect of paracetamol on the parasitological diagnosis of falciparum malaria through a clinical trial.\u0000\u0000\u0000\u0000This is a conjoined study that includes a prospective and descriptive study and a randomized, placebo-controlled, double-blind, and parallel-group clinical trial. The descriptive study included 846 participants from various states in Sudan. The targeted study subjects were the public and health professionals and the study was conducted utilizing an online-based questionnaire. The clinical trial included 325 patients with uncomplicated falciparum attending two primary healthcare outpatient clinics in Gezira state, Sudan. The patients were randomly allocated to receive either placebo tablets or 500 mg of oral paracetamol after the first blood smear sample was taken. The second blood smear samples were taken 2 h after taking treatment. Parasite density estimation and other parasitological data were obtained from each sample before and after treatment.\u0000\u0000\u0000\u0000The majority of the public thinks that paracetamol affects the parasitological diagnosis of malaria (76.21%, n = 330/433). Personal experience and family and friends were the most dominant information sources for the public (31.20% and 28.01% respectively), while scholarly articles were the most common source of information for the health professional group (45.03%, n = 186/413). No significant differences between the parasitological findings acquired before and after taking the treatments among both the paracetamol group (P = 0.22) and the placebo group (P = 0.12). The parasite density mean for the paracetamol group differed by 16.31 P/μL after taking paracetamol, while the placebo group parasite density mean differed by 15.34 P/μL. The treatments did not inflict impacts on the advanced microscopic features of Plasmodium falciparum blood smears.\u0000\u0000\u0000\u0000Paracetamol does not affect the parasitological diagnosis of falciparum malaria.\u0000","PeriodicalId":369069,"journal":{"name":"Global Journal of Health Sciences and Research","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122385320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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