Irene Latras-Cortés, Sandra Diez Ruiz, Luis Vaquero Ayala, Santiago Vivas Alegre, Ana Belén Domínguez-Carbajo
{"title":"Beneficios del implante percutáneo de la válvula aórtica en la hemorragia digestiva","authors":"Irene Latras-Cortés, Sandra Diez Ruiz, Luis Vaquero Ayala, Santiago Vivas Alegre, Ana Belén Domínguez-Carbajo","doi":"10.1016/j.rccl.2023.12.002","DOIUrl":"10.1016/j.rccl.2023.12.002","url":null,"abstract":"","PeriodicalId":36870,"journal":{"name":"REC: CardioClinics","volume":"59 1","pages":"Pages 71-72"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139540090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
María Paula Russo , María Florencia Grande Ratti , Vanina Laura Pagotto , María Florencia Correa , Mariana Andrea Burgos , María Florencia Indo
{"title":"Sobretratamiento en personas con enfermedad cardiovascular establecida y diabetes tipo 2","authors":"María Paula Russo , María Florencia Grande Ratti , Vanina Laura Pagotto , María Florencia Correa , Mariana Andrea Burgos , María Florencia Indo","doi":"10.1016/j.rccl.2023.09.004","DOIUrl":"10.1016/j.rccl.2023.09.004","url":null,"abstract":"<div><h3>Introduction and objectives</h3><p>To estimate the prevalence of patients with established cardiovascular disease (CVD) and type 2 diabetes mellitus (DM2) who are overtreated.</p></div><div><h3>Methods</h3><p>Cross-sectional study, which included a consecutive sample of adults, with CVD (defined as a history of acute myocardial infarction, cerebrovascular accident and/or peripheral arterial disease) and DM2, active affiliates to institutional prepaid of a high complexity hospital in Argentina. Overtreatment was defined as those who had at least one glycosylated hemoglobin (HbA1c) value <7% in the last year and had been prescribed at least one drug with a high risk of hypoglycemia (insulin and/or sulfonylureas and/or glinides) as part of their therapeutic scheme.</p></div><div><h3>Results</h3><p>A total of 1153 persons with established CVD and DM2 were included, 68.08% male, with a mean age of 75.38 years (SD<!--> <!-->=<!--> <!-->10.07), 89.59% had arterial hypertension, 52.82% were active smokers, and the average body mass index was 29.80<!--> <!-->kg/m<sup>2</sup> (SD<!--> <!-->=<!--> <!-->5.03). As established CVD, 63.23% had a history of coronary disease, 38.86% of stroke, and 13.44% of peripheral vascular disease. The prevalence of overtreatment was 13.87% (95%CI: 11.93-16.01). Among the 160 overtreated patients, 88.13% were prescribed insulin, 12.5% sulfonylureas, and 4.38% glinides.</p></div><div><h3>Conclusions</h3><p>The prevalence of overtreatment among individuals with CVD and DM2 (14%) is comparatively lower than the rates reported in other studies. However, the clinical implications of these findings remain significant: the potential escalation of adverse side effects, such as hypoglycemia; the subsequent elevation in healthcare expenses due to superfluous treatments; and the possible strain on the healthcare system's capabilities, including the diversion of crucial medical resources —such as physician hours, essential equipment, and hospital beds— from those who are genuinely in need.</p></div>","PeriodicalId":36870,"journal":{"name":"REC: CardioClinics","volume":"59 1","pages":"Pages 46-52"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136093047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marcelina Carretero , Eugenia Villanueva , Diego Pérez de Arenaza , Elsa Mercedes Nucifora , María Soledad Sáez , Patricia Beatriz Sorroche , Erika Bárbara Brulc , María Adela Aguirre , María Lourdes Posadas-Martínez
{"title":"Evolución de los subtipos, características clínicas y métodos diagnósticos de la amiloidosis en un registro institucional","authors":"Marcelina Carretero , Eugenia Villanueva , Diego Pérez de Arenaza , Elsa Mercedes Nucifora , María Soledad Sáez , Patricia Beatriz Sorroche , Erika Bárbara Brulc , María Adela Aguirre , María Lourdes Posadas-Martínez","doi":"10.1016/j.rccl.2023.09.001","DOIUrl":"10.1016/j.rccl.2023.09.001","url":null,"abstract":"<div><h3>Introduction and objectives</h3><p>Amyloidosis is a rare disease. Advances in understanding and diagnosis have increased detection of the disease. Our objective was to describe the evolution in the distribution of amyloidosis subtypes, the clinical characteristics and diagnostic methods used in an Institutional Registry of Amyloidosis in Argentina over 18 years.</p></div><div><h3>Methods</h3><p>Consecutive patients with AL amyloidosis, ATTR wild type, ATTR variant, and AA between 1 January 2005 and 31 December 2022 were included. The evolution in the distribution of subtypes, clinical characteristics and diagnostic modalities was analyzed in three subperiods: 2005-2010; 2011-2016; 2017-2022.</p></div><div><h3>Results</h3><p>A total of 258 patients were included. The distribution of amyloidosis subtypes varied throughout the study period. AL amyloidosis was the most frequent in the first subperiods (85% and 63% respectively), while ATTR wild type amyloidosis predominated in the last subperiod (49%) (<em>P</em> <!--><<!--> <!-->.001). The age at diagnosis increased from 60 years [interquartile range (IIC): 52-69] between 2005-2010 to 76 years [IIC: 66-83] between 2017-2022 (<em>P</em> <!--><<!--> <!-->.001). Heart failure was common in all subperiods, with an increase in the last one. The history of carpal tunnel was observed more in the last subperiod.</p></div><div><h3>Conclusions</h3><p>In this study we observed an increase in the detection of cases of systemic amyloidosis and ATTR wild type in particular. In addition, a transition towards non-invasive diagnostic methods was evidenced, such as DPD scintigraphy, reflecting technological advances in disease detection.</p></div>","PeriodicalId":36870,"journal":{"name":"REC: CardioClinics","volume":"59 1","pages":"Pages 7-13"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134935723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Diego Mauricio Gómez-García , Liliana Bejarano-Barragán , Herney Andrés García-Perdomo
{"title":"Estrategias de prevención de la insuficiencia cardiaca: enfoque integral en diferentes momentos de la enfermedad","authors":"Diego Mauricio Gómez-García , Liliana Bejarano-Barragán , Herney Andrés García-Perdomo","doi":"10.1016/j.rccl.2023.09.008","DOIUrl":"10.1016/j.rccl.2023.09.008","url":null,"abstract":"<div><p>Heart failure (HF) is considered a public health problem that affects a significant proportion of the population, especially older adults, leading to substantial morbidity, mortality, and high healthcare costs. Therefore, it becomes necessary to adopt prevention strategies from initial medical care and follow-up as a primary healthcare measure. With the aging population, the increase in cardiovascular risk factors in the general population, a higher survival rate after cardiovascular ischemic events, and an increase in life expectancy, the prevalence and incidence of HF is expected to rise in the upcoming years. The development of symptomatic heart failure is associated with a worsening prognosis despite treatment in accordance with current guidelines, making it a significant source of healthcare resource consumption. Hence, it is relevant to discuss the levels of HF prevention through interventions on risk factors, the disease's progression in those in the early stages of HF, as well as in those in the established and advanced stages of the disease to understand the impact of preventive measures on prognosis when implemented at different stages of the disease.</p></div>","PeriodicalId":36870,"journal":{"name":"REC: CardioClinics","volume":"59 1","pages":"Pages 61-70"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136008429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alberto Otero-Cacho , Diego López-Otero , Manuel Insúa Villa , Brais Díaz-Fernández , María Bastos-Fernández , Vicente Pérez-Muñuzuri , Alberto P. Muñuzuri , José Ramón González-Juanatey
{"title":"Validation of a new model of non-invasive functional assessment of coronary lesions by computer tomography fractional flow reserve","authors":"Alberto Otero-Cacho , Diego López-Otero , Manuel Insúa Villa , Brais Díaz-Fernández , María Bastos-Fernández , Vicente Pérez-Muñuzuri , Alberto P. Muñuzuri , José Ramón González-Juanatey","doi":"10.1016/j.rccl.2023.07.004","DOIUrl":"10.1016/j.rccl.2023.07.004","url":null,"abstract":"<div><h3>Introduction and objectives</h3><p>Computed tomography of coronary arteries (CTCA) is emerging as the gold standard in the initial evaluation of chest pain. The aim of this study is to calculate the diagnostic performance and clinical usefulness of numerical models of arterial channels flow to assess non-invasive coronary fractional flow reserve by computed tomography (FFRct) compared to assessment by invasive angiography (FFR).</p></div><div><h3>Methods</h3><p>Computation of FFR from CTCA images was performed on 39 vessels in 32 patients who followed the usual clinical protocol including invasive coronary angiography and FFR following the usual clinical protocol. From the segmentation of the CTCA images, 3D geometry is obtained, and computational fluid dynamics techniques are applied to accurately reproduce the circulation of blood considering steady and unsteady circulatory conditions. Additional parameters as wall shear stress, stenosis resistance index and ΔFFRct were also calculated.</p></div><div><h3>Results</h3><p>The results obtained show a good correlation between FFRct and invasive FFR, without obtaining false positives values. In addition, no differences were observed between the simulations considering steady conditions or those considering the transient. Additional parameters as wall shear stress, stenosis resistance, and ΔFFRct also showed a good correlation with the invasive values.</p></div><div><h3>Conclusions</h3><p>This new model for calculating the FFRct from non-invasive 3D medical images of coronary tree has shown good agreement with those obtained using invasive techniques. Parameters as wall shear stress, stenosis resistance and ΔFFRct provide useful information that could be helpful in medical decision-making in those situations with FFR values close to the cut-off zone.</p></div>","PeriodicalId":36870,"journal":{"name":"REC: CardioClinics","volume":"59 1","pages":"Pages 35-45"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44327622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maria Inês Barradas, Fabiana Duarte, Inês Coutinho dos Santos, André Viveiros Monteiro, Anabela Tavares, Dinis Martins
{"title":"Remote monitoring in remote places: an archipelago experience in heart failure patients with cardiac electronic devices","authors":"Maria Inês Barradas, Fabiana Duarte, Inês Coutinho dos Santos, André Viveiros Monteiro, Anabela Tavares, Dinis Martins","doi":"10.1016/j.rccl.2023.09.002","DOIUrl":"10.1016/j.rccl.2023.09.002","url":null,"abstract":"<div><h3>Introduction and objectives</h3><p>Remote monitoring (RM) is a new tool in heart failure (HF) patients with cardiac implantable electronic devices but its effect in clinical outcomes is still uncertain. In remote regions as islands HF management is even more challenging and RM may have a different impact. We aimed to assess its impact in clinical outcomes in an insular reality.</p></div><div><h3>Methods</h3><p>This was a retrospective, non-randomized study conducted in our hospital, that is the reference center of a nine-island archipelago. Patients in the HF remote monitoring program were matched 1:1 with usual standard of care patients.</p></div><div><h3>Results</h3><p>From 307 patients, 96 with RM (group 1 – G1) were matched 1:1 according to age ±2 years and gender with 96 usual standard of care (group 2 – G2) (mean age 69 years, 76% males, mean follow-up period 55 months). Primary endpoint was cardiovascular (CV) mortality and secondary endpoints all-cause mortality, HF hospitalizations at 12 months and at FUP. CV mortality was lower in G1 (hazard ratio [HR] 6.7; 95% confidence interval [95% CI] 1.46–30.87; <em>P</em> <!-->=<!--> <!-->.004), as well as all-cause mortality (HR, 5.7; 95% CI, 1.85–17.39; <em>P</em> <!--><<!--> <!-->.001) and HF hospitalizations at 12 months (<em>P</em> <!-->=<!--> <!-->.02) with a tendency toward less hospitalizations during follow-up.</p></div><div><h3>Conclusions</h3><p>RM in the management of HF patients with cardiac implantable electronic devices in a remote geographic location, as a nine-island archipelago, was effective in reducing CV mortality, all-cause mortality and HF hospitalizations.</p></div>","PeriodicalId":36870,"journal":{"name":"REC: CardioClinics","volume":"59 1","pages":"Pages 14-22"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135661546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cambios en el diagnóstico de la amiloidosis en las últimas dos décadas. ¿Que 20 años no es nada?","authors":"Fernando Domínguez","doi":"10.1016/j.rccl.2023.10.005","DOIUrl":"10.1016/j.rccl.2023.10.005","url":null,"abstract":"","PeriodicalId":36870,"journal":{"name":"REC: CardioClinics","volume":"59 1","pages":"Pages 1-3"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139291712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}