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Fasten your seatbelts: 2018–2019 influenza season is coming 系好安全带:2018-2019年流感季节即将来临
JAMMI Pub Date : 2018-06-01 DOI: 10.3138/JAMMI.2018.02.14
L. Valiquette, K. Laupland
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引用次数: 0
Reforming Canada’s Special Access Programme (SAP) to improve access to off-patent essential medicines 改革加拿大的特殊获取方案(SAP),以改善非专利基本药物的获取
JAMMI Pub Date : 2018-06-01 DOI: 10.3138/JAMMI.2018.01.04
Adam R. Houston, Catherine-Marie Blais, S. Houston, B. J. Ward
{"title":"Reforming Canada’s Special Access Programme (SAP) to improve access to off-patent essential medicines","authors":"Adam R. Houston, Catherine-Marie Blais, S. Houston, B. J. Ward","doi":"10.3138/JAMMI.2018.01.04","DOIUrl":"https://doi.org/10.3138/JAMMI.2018.01.04","url":null,"abstract":"Many essential medicines, including basic drugs such as albendazole, do not have approval to be marketed in Canada. Instead, they are only available through a federal government mechanism: the Special Access Programme (SAP). SAP was designed as a mechanism to provide emergency access to new drugs not yet authorized for sale, not for proven medicines that appear on the World Health Organization (WHO) Model List of Essential Medicines. Because it was never intended or designed to fulfill this function, SAP creates needless access barriers that inhibit timely and effective care, particularly for patients with tropical, parasitic, and other infectious diseases. Regulatory changes to resolve this problem are readily achievable and should be prioritized.","PeriodicalId":36782,"journal":{"name":"JAMMI","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3138/JAMMI.2018.01.04","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41551161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Recurrent meningitis caused by Streptococcus pneumoniae serotype 15C associated with Wiskott-Aldrich syndrome 肺炎链球菌血清型15C引起的与Wiskott-Aldrich综合征相关的复发性脑膜炎
JAMMI Pub Date : 2018-06-01 DOI: 10.3138/JAMMI.2017-0007
Vic Eton, James Beveridge, M. Ulanova
{"title":"Recurrent meningitis caused by Streptococcus pneumoniae serotype 15C associated with Wiskott-Aldrich syndrome","authors":"Vic Eton, James Beveridge, M. Ulanova","doi":"10.3138/JAMMI.2017-0007","DOIUrl":"https://doi.org/10.3138/JAMMI.2017-0007","url":null,"abstract":"Streptococcus pneumoniae is an encapsulated bacterium capable of causing invasive disease in susceptible individuals, including immunocompromised and asplenic patients. Wiskott-Aldrich syndrome (WAS) is a primary immunodeficiency disease with myriad manifestations; it can cause thrombocytopenia, platelet dysfunction, selective antibody deficiency, and predisposition to bacterial infections. A 24-year-old Métis man presented to a Northern Ontario emergency department with several days’ history of malaise, headache, and nuchal rigidity. Within 5 months, he presented again with similar symptoms. In both instances, S. pneumoniae serotype 15C was isolated from his cerebrospinal fluid. He was successfully treated with cefotaxime both times. The patient’s past medical history included WAS, splenectomy, Epstein-Barr virus-associated lymphoma treated with bone marrow transplant, and prior cases of pneumococcal meningitis and pneumonia. He was restarted on indefinite penicillin V prophylaxis. This is the first described case of WAS in a man of mixed European and Indigenous North American descent. We report recurrent invasive pneumococcal disease in an asplenic individual caused by an emerging invasive serotype.","PeriodicalId":36782,"journal":{"name":"JAMMI","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3138/JAMMI.2017-0007","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49461479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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