International Journal of Pediatrics and Adolescent Medicine最新文献

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Outcomes and predictors of early emergency department discharge among children with acute gastroenteritis and moderate dehydration 急性胃肠炎和中度脱水患儿早期急诊出院的结局和预测因素
International Journal of Pediatrics and Adolescent Medicine Pub Date : 2022-03-01 DOI: 10.1016/j.ijpam.2021.03.003
Mohammed Khalaf Almutairi , Abdullah M. Al-Saleh , Bedoor H. Al Qadrah , Nora Tarig Sarhan , Norah Abdullah Alshehri , Naila A. Shaheen
{"title":"Outcomes and predictors of early emergency department discharge among children with acute gastroenteritis and moderate dehydration","authors":"Mohammed Khalaf Almutairi ,&nbsp;Abdullah M. Al-Saleh ,&nbsp;Bedoor H. Al Qadrah ,&nbsp;Nora Tarig Sarhan ,&nbsp;Norah Abdullah Alshehri ,&nbsp;Naila A. Shaheen","doi":"10.1016/j.ijpam.2021.03.003","DOIUrl":"10.1016/j.ijpam.2021.03.003","url":null,"abstract":"<div><h3>Background</h3><p>Gastroenteritis is one of the most common diseases that affects children and remains a leading cause of morbidity and mortality around the world. There is conflicting evidence regarding the effect of rapid intravenous fluid regimen on the clinical outcome of patients with acute gastroenteritis. This study aimed to assess the current practice of intravenous hydration on the clinical outcomes of pediatric patients with acute gastroenteritis and determine the predictive factors for early discharge and emergency department (ED) revisit.</p></div><div><h3>Methods</h3><p>A cohort study was carried out among children aged from 1 month to 14 years who presented to the ED in a tertiary care hospital between September 2015 and September 2017. Children diagnosed with acute gastroenteritis and moderate dehydration who require intravenous hydration were included in the study. The patients were followed up until discharge from ED, admission to the hospital or revisit to the ED. Collected variables were demographics, presenting symptoms, biochemical marker, amount of intravenous fluid (IVF) received and prescription of anti-emetics. Descriptive statistics were summarized as mean, standard deviation for continuous variables and proportions for categorical variables. Logistic regression was used to identify risk factors.</p></div><div><h3>Results</h3><p>Out of 284 patients, 148 (52%) were males, 20 (7%) were infants, 80 (28%) were toddlers, 90 (32%) were in preschool, 88 (31%) were in school and 6 (2.1%) were adolescents. No significant difference was observed in the admission rate, discharge within 12 h or less and ED revisits for those who received IVF ≥40 ml/kg as compared to those who received &lt;40 ml/kg. Patients with bicarbonate level closer to normal are more likely to be discharged after 4 h (odds ratio (OR) 1.2 and 95% CI 1.12–1.43). Patients presenting only with vomiting/diarrhoea were less likely to revisit ED (OR 0.33 (95% CI 0.143 - 0.776), while patients with an increase in CO<sub>2</sub> level (OR 1.19 and 95% CI 1.0 -1.436) and anion gap (OR 1.29 and 95% CI 1.08–1.54) were more likely to revisit within 1 week post discharge.</p></div><div><h3>Conclusion</h3><p>This study did not show any additional benefits of receiving IVF ≥ 40 ml/kg over 4 h neither in early discharge nor in reducing the ED revisit. CO<sub>2</sub> closer to normal was a significant predictor for early discharge in 4 h where the closer level of CO<sub>2</sub> and AGAP were associated with an increase in the chance of a revisit to the ED within 1 week after discharge.</p></div>","PeriodicalId":36646,"journal":{"name":"International Journal of Pediatrics and Adolescent Medicine","volume":"9 1","pages":"Pages 27-31"},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ijpam.2021.03.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90705416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Development and validation of an Arabic pediatric sensorimotor development test 阿拉伯儿童感觉运动发展测试的开发和验证
International Journal of Pediatrics and Adolescent Medicine Pub Date : 2022-03-01 DOI: 10.1016/j.ijpam.2021.03.005
Lamya Alabdulkarim
{"title":"Development and validation of an Arabic pediatric sensorimotor development test","authors":"Lamya Alabdulkarim","doi":"10.1016/j.ijpam.2021.03.005","DOIUrl":"10.1016/j.ijpam.2021.03.005","url":null,"abstract":"<div><h3>Aim</h3><p>The main concern of Arab rehabilitation therapists is the paucity of a valid clinical assessment tool that fits the demographic and cultural specificities of the pediatric population. This study aimed to describe and validate a localized evidence-based instrument for assessing sensorimotor development in Saudi Arabian children.</p></div><div><h3>Methods</h3><p>The Arabic Pediatric Sensorimotor Development Test (A-P-SMDT) designed for Saudi Arabian preschoolers was used for 110 children (3–6 years) in this prospective cross-sectional study. The instrument has two constructs: sensorimotor integration and visual perception and visuomotor integration, with 10 themes and 52 items. Face, content and construct validity and internal consistency were calculated. Cronbach’s α was used to test internal consistency. A Kaiser–Meyer–Olkin test and Bartlett’s test of sphericity were used to test sampling adequacy.</p></div><div><h3>Results</h3><p>Five clinicians and 25 senior clinicians reported good face validity. The content validity index was 3.45, indicating the degree to which the content of the test matches a content domain. The Cronbach’s α coefficient was 0.95, indicating excellent internal consistency. The Kaiser–Meyer–Olkin measure for sampling adequacy was 0.80. Bartlett’s test of sphericity was significant (chi-square = 3400.43, df = 122, <em>p</em> = .00), indicating that the 10 test domains had a good level of correlation.</p></div><div><h3>Conclusion</h3><p>The preliminary results on the Arabic Pediatric Sensorimotor Development Test showed acceptable reliability and validity, which could be useful for identifying children at risk of sensorimotor disorders and delays in a mainstream non-clinical population.</p></div>","PeriodicalId":36646,"journal":{"name":"International Journal of Pediatrics and Adolescent Medicine","volume":"9 1","pages":"Pages 36-40"},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ijpam.2021.03.005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76179582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Urgent need to standardize labelling of acetaminophen-paediatric liquid drug products in Saudi Arabia 沙特阿拉伯迫切需要规范对乙酰氨基酚儿科液体药品的标签
International Journal of Pediatrics and Adolescent Medicine Pub Date : 2022-03-01 DOI: 10.1016/j.ijpam.2021.09.001
Nahar AlRuwaili , Faten Zaidan , Areej AlFattani , Saud Alenazi
{"title":"Urgent need to standardize labelling of acetaminophen-paediatric liquid drug products in Saudi Arabia","authors":"Nahar AlRuwaili ,&nbsp;Faten Zaidan ,&nbsp;Areej AlFattani ,&nbsp;Saud Alenazi","doi":"10.1016/j.ijpam.2021.09.001","DOIUrl":"10.1016/j.ijpam.2021.09.001","url":null,"abstract":"<div><p>In this study, dosing instructions in package inserts of all 12 paediatric liquid acetaminophen products registered in pharmacies in the Kingdom of Saudi Arabia were analysed to determine the potential for administering a supratherapeutic dose of acetaminophen. Doses in millilitres were calculated as mg/kg for four age groups: three months old, one year old, six years old, and twelve years old, and based on the 3rd, 50th, and 75th weight percentiles of each age group.</p><p>Acetaminophen concentrations in the products varied, and only two products included Arabic language instructions. The dosing instructions in eight products included an age overlap. The most affected age group was the 1-year-old group, with 21 supratherapeutic doses across all 12 products. The least affected age group was the 12-year-old group, with 8 supratherapeutic doses in total.</p><p>The absence of strict supervision and monitoring of labels of paediatric liquid acetaminophen products increases the risk of liver toxicity in children. Therefore, we call for an immediate standardisation of all dosing instructions regarding the dose per weight and the inclusion of instructions in Arabic.</p></div>","PeriodicalId":36646,"journal":{"name":"International Journal of Pediatrics and Adolescent Medicine","volume":"9 1","pages":"Pages 62-65"},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/6c/6e/main.PMC9072244.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10617102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The first report on CFTR mutations of meconium ileus in cystic fibrosis population in Saudi Arabia: A single center review 沙特阿拉伯囊性纤维化人群中胎粪肠梗阻CFTR突变的第一篇报道:单中心综述
International Journal of Pediatrics and Adolescent Medicine Pub Date : 2022-03-01 DOI: 10.1016/j.ijpam.2021.03.008
Hanaa Banjar , Raef Qeretli , Ali Ramadan , Abdullah Al-Ibraheem , Fahad Bnatig
{"title":"The first report on CFTR mutations of meconium ileus in cystic fibrosis population in Saudi Arabia: A single center review","authors":"Hanaa Banjar ,&nbsp;Raef Qeretli ,&nbsp;Ali Ramadan ,&nbsp;Abdullah Al-Ibraheem ,&nbsp;Fahad Bnatig","doi":"10.1016/j.ijpam.2021.03.008","DOIUrl":"10.1016/j.ijpam.2021.03.008","url":null,"abstract":"<div><h3>Introduction</h3><p>Meconium ileus (MI) is one of the most common causes of intestinal obstruction in newborns. It is the earliest clinical manifestation of cystic fibrosis (CF). MI is suspected if a baby fails to pass meconium shortly after birth and develops symptoms of bowel obstruction, such as distention of the abdomen or vomiting. MI can lead to bowel perforation, a twisting of the bowel, or inflammation and infection of the abdominal cavity.</p></div><div><h3>Objectives</h3><p>To find the incidence and prevalence of meconium ileus in cystic fibrosis patients and to report on the most common gene mutation of MI in CF patients.</p></div><div><h3>Methodology</h3><p>Retrospective review of the medical documentations of all MI patients during the period of 1989–2018.</p></div><div><h3>Results</h3><p>A total of 40 CF confirmed patients were presented with MI. Twenty-nine patients (71%) are alive and 11 patients (29%) died or lost to follow-up. The following CFTR mutations were found: Eight patients (20%) with c.2988+1G&gt;A; Intron 18. Seven patients (17.5%) with c.1418delG; Exon 11. Five patients (12.5%) with c.579+1G&gt;T; Intron 5. Four patients (10%) with c.1911delG; Exon 14. Four patients (10%) with c.1521_1523delCTT; Exon 11. Four patients (10%) with c.416A&gt;T; Exon 13. Three patients (7.5%) with c.2421A&gt;G; Exon 14. Two patients (5%) with c.3908A&gt;C; Exon 21. One patient (2.5%) with c.3889dupT; Exon 24. One patient (2.5%) with c.1657C&gt;T; Exon 12. One patient (2.5%) with c.2547C&gt;A; Exon 14a. Eighteen patients (45%) were presented with vomiting, 38 patients (95%) had postnatal radiological findings, 7 patients (17.5%) had electrolytes imbalance. Five patients (12.5%) had cholestasis and 4 patients (10%) developed chronic liver disease. Thirty-five patients (79.5%) underwent surgical repair and 9 patients (20.5%) were treated medically. Mean age of operation was 2.25 (2) days. Of 9 patients, 6 (66.6%) were treated with gastrograffin enema, 2 patients (22.2%) with oral N-acetylcysteine and 1 patient (11.1%) with saline rectal wash. Thirteen patients (31.5%) required TPN. Five patients had recurrent operation.</p></div><div><h3>Conclusion</h3><p>CF and meconium ileus are commonly present in CF patients in Saudi Arabia. Prognosis is similar to other CFs without MI, if treated early. Thirty percent of our CF/MI patients have intronic mutations.</p></div>","PeriodicalId":36646,"journal":{"name":"International Journal of Pediatrics and Adolescent Medicine","volume":"9 1","pages":"Pages 32-35"},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ijpam.2021.03.008","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76270928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Training pediatric residents in point-of-care ultrasound: An assessment of the needs and barriers to acquire the skill 对儿科住院医师进行护理点超声波培训:对获得该技能的需求和障碍的评估
International Journal of Pediatrics and Adolescent Medicine Pub Date : 2022-03-01 DOI: 10.1016/j.ijpam.2021.06.001
Syed Furrukh Jamil , Rajkumar Rajendram
{"title":"Training pediatric residents in point-of-care ultrasound: An assessment of the needs and barriers to acquire the skill","authors":"Syed Furrukh Jamil ,&nbsp;Rajkumar Rajendram","doi":"10.1016/j.ijpam.2021.06.001","DOIUrl":"https://doi.org/10.1016/j.ijpam.2021.06.001","url":null,"abstract":"<div><h3>Introduction</h3><p>The use of point-of-care ultrasound (POCU) is increasing globally. However, owing to the epidemiology of diseases and local management strategies, POCU may not be universally applicable. Before developing a POCU training program, because of limited resources for medical education, it was pivotal to conduct a needs assessment and identify the training barriers.</p></div><div><h3>Methods</h3><p>This study used a validated paper questionnaire. The survey instrument was distributed to 120 pediatric residents (male 60, female 60) training at our institution to assess their self-reported level of skill in POCU, and their perceptions with regard to the applicability of POCU, measured with a 5-point Likert scale. The skills deficit was measured by subtracting the self-reported level of skills in lung, cardiac, and abdominal POCU from the perceived applicability of POCU.</p></div><div><h3>Results</h3><p>Fifty-nine residents participated, resulting in a response rate of 50 and 48% (n = 29) for the male group, and 50% (n = 30) for the female group. The level of knowledge and proficiency was low. Scanning for free abdominal fluid was deemed the most applicable (mean 4.2 ± SD 1.1); however, the use of POCU to detect consolidation was considered least applicable (mean 2.7 ± SD 1.3). The skills deficit was highest for an abdominal POCU (mean 2.4 ± SD 1.6) and lowest for lung ultrasound (mean 1.4 ± SD 1.6). Although the majority (n = 48) agreed that this skill was essential, 3 (5%) had no interest, and 39% (n = 23) indicated a lack of time to acquire the skill.</p></div><div><h3>Conclusions</h3><p>Though pediatric residents in Saudi Arabia agree that POCU is an essential skill, large skill deficits exist, supporting the necessity to provide POCU training. However, there are several barriers to overcome to achieve this.</p></div>","PeriodicalId":36646,"journal":{"name":"International Journal of Pediatrics and Adolescent Medicine","volume":"9 1","pages":"Pages 49-55"},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ijpam.2021.06.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72290247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pediatric hypertension: Review of the definition, diagnosis, and initial management 儿童高血压:定义、诊断和初始治疗的回顾
International Journal of Pediatrics and Adolescent Medicine Pub Date : 2022-03-01 DOI: 10.1016/j.ijpam.2020.09.005
Jason Thomas , Emily Stonebrook , Mahmoud Kallash
{"title":"Pediatric hypertension: Review of the definition, diagnosis, and initial management","authors":"Jason Thomas ,&nbsp;Emily Stonebrook ,&nbsp;Mahmoud Kallash","doi":"10.1016/j.ijpam.2020.09.005","DOIUrl":"10.1016/j.ijpam.2020.09.005","url":null,"abstract":"<div><p>Pediatric hypertension (HTN) is a significant and growing health concern. While previously thought to be an uncommon condition in the pediatric population, recent studies have shown an increase in incidence, which is largely due to the obesity epidemic. Accordingly, primary or idiopathic HTN has become more prevalent compared to secondary causes of HTN. The incidence of hypertension is about 3.5%; however, it may be higher as HTN can be missed during routine pediatric well visits. Since childhood HTN frequently tracks into adulthood and is a risk factor for both cardiovascular disease and progression of renal disease; early diagnosis and management of this condition is essential. In this review, we will discuss the approach of a pediatric nephrologist for evaluation and management of pediatric HTN.</p></div>","PeriodicalId":36646,"journal":{"name":"International Journal of Pediatrics and Adolescent Medicine","volume":"9 1","pages":"Pages 1-6"},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ijpam.2020.09.005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86881689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Pediatric high risk neuroblastoma with autologous stem cell transplant – 20 years of experience 自体干细胞移植治疗小儿高危神经母细胞瘤- 20年经验
International Journal of Pediatrics and Adolescent Medicine Pub Date : 2021-12-01 DOI: 10.1016/j.ijpam.2021.02.006
Saadiya Khan, Khulood AlSayyad, Khawar Siddiqui, Awatif AlAnazi, Amal AlSeraihy, Ali AlAhmari, Hassan ElSolh, Ibrahim Ghemlas, Hawazen AlSaedi, Abdullah AlJefri, Afshan Ali, Ibrahim AlFawaz, Amani AlKofide, Mouhab Ayas
{"title":"Pediatric high risk neuroblastoma with autologous stem cell transplant – 20 years of experience","authors":"Saadiya Khan,&nbsp;Khulood AlSayyad,&nbsp;Khawar Siddiqui,&nbsp;Awatif AlAnazi,&nbsp;Amal AlSeraihy,&nbsp;Ali AlAhmari,&nbsp;Hassan ElSolh,&nbsp;Ibrahim Ghemlas,&nbsp;Hawazen AlSaedi,&nbsp;Abdullah AlJefri,&nbsp;Afshan Ali,&nbsp;Ibrahim AlFawaz,&nbsp;Amani AlKofide,&nbsp;Mouhab Ayas","doi":"10.1016/j.ijpam.2021.02.006","DOIUrl":"10.1016/j.ijpam.2021.02.006","url":null,"abstract":"<div><h3>Background and Objective</h3><p>Neuroblastoma is the most common extracranial solid tumor found in pediatric patients. High-risk neuroblastoma (HR-NBL) can be characterized by metastasis, age, and other tumor characteristics that result in an adverse outlook for this patient cohort. The standard of care includes induction chemotherapy, surgery, followed by stem cell autologous transplant (ASCT), and later, antidisialoganglioside (anti-GD2) antibodies. In this study, we provide the survival and toxicity data of our HR-NBL patients treated with a single ASCT.</p></div><div><h3>Methods</h3><p>We retrospectively analyzed pediatric HR-NBL patients treated with single ASCT after a carboplatin, etoposide, and melphalan (CEM) regimen in our institution between January 1993 and December 2014.</p></div><div><h3>Results</h3><p>There were 99 evaluable patients with male predominance. The median age at diagnosis was 3 years. Most of our HR-NBL patients were stage 4 (88%). All patients received ASCT. Peripheral blood was the graft source in 58% of the patients. Time for hematological count recovery with bone marrow as a graft source was prolonged but not statistically significant when compared with PBSCs. Of all the patients, 58% received radiation therapy to residual disease. Overt secondary leukemia was not seen in any of these patients. Three-year overall survival (OS) was 68.5% ± 5.2% and the 3-year event-free survival (EFS) was (48.3% ± 5.2%).</p></div><div><h3>Conclusion</h3><p>Our HR-NBL patients tolerated high-dose chemotherapy well followed by single autologous stem cell transplant. Tandem transplant is a feasible option in our patient cohort. Apart from secondary solid tumors, there were no long-term complications seen.</p></div>","PeriodicalId":36646,"journal":{"name":"International Journal of Pediatrics and Adolescent Medicine","volume":"8 4","pages":"Pages 253-257"},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ijpam.2021.02.006","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39317892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
A rare cerebellar vermis high-grade neuroepithelial tumor: Radiological-pathological correlation 一例罕见的小脑蚓部高级别神经上皮肿瘤:影像学与病理学的相关性
International Journal of Pediatrics and Adolescent Medicine Pub Date : 2021-12-01 DOI: 10.1016/j.ijpam.2020.12.004
Amna Kashgari , Rases Al Otaibi , Fahd Al Sufiani , Moutasem Azzubi
{"title":"A rare cerebellar vermis high-grade neuroepithelial tumor: Radiological-pathological correlation","authors":"Amna Kashgari ,&nbsp;Rases Al Otaibi ,&nbsp;Fahd Al Sufiani ,&nbsp;Moutasem Azzubi","doi":"10.1016/j.ijpam.2020.12.004","DOIUrl":"10.1016/j.ijpam.2020.12.004","url":null,"abstract":"<div><p>Neuroepithelial tumors, formerly known as primitive neuroectodermal tumors of the central nervous system, are reclassified under embryonal tumors in the 2016 WHO Classification of Tumors of the Central Nervous System. The tumor has two known genetic alterations: HGNET-MN1 and HGNET-BCOR. Previously, radiological features of the tumor have been reported as large, intra-axial lesions in the cerebral or cerebellar hemisphere, which presents mild adjacent edema. Here, we report the first case of high-grade neuroepithelial tumor not elsewhere classified (HGNET-NEC) arising from the cerebellar vermis, demonstrating good outcomes in clinical follow-up when compared with previously known types.</p></div>","PeriodicalId":36646,"journal":{"name":"International Journal of Pediatrics and Adolescent Medicine","volume":"8 4","pages":"Pages 264-267"},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ijpam.2020.12.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39318298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Coarctation of Aorta in Turner Mosaicism 特纳镶嵌画中的主动脉缩窄
International Journal of Pediatrics and Adolescent Medicine Pub Date : 2021-12-01 DOI: 10.1016/j.ijpam.2020.03.005
Vanessa Gorito , Cristina Baptista , Paulo Santos , Ana Margarida Costa , Joana Carvalho
{"title":"Coarctation of Aorta in Turner Mosaicism","authors":"Vanessa Gorito ,&nbsp;Cristina Baptista ,&nbsp;Paulo Santos ,&nbsp;Ana Margarida Costa ,&nbsp;Joana Carvalho","doi":"10.1016/j.ijpam.2020.03.005","DOIUrl":"10.1016/j.ijpam.2020.03.005","url":null,"abstract":"<div><p>The prevalence of hypertension in the pediatric age range is estimated at 1–5% worldwide, with higher rates in adolescence. Although primary hypertension is more common, due to the increasing prevalence of obesity and metabolic syndrome among adolescents, secondary hypertension should be always considered and excluded. We present the case of an adolescent with secondary hypertension and a challenging diagnosis associated with coarctation of aorta and Turner Mosaicism.</p></div>","PeriodicalId":36646,"journal":{"name":"International Journal of Pediatrics and Adolescent Medicine","volume":"8 4","pages":"Pages 268-270"},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ijpam.2020.03.005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39318300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
When is asthma not guilty? 什么时候哮喘是无罪的?
International Journal of Pediatrics and Adolescent Medicine Pub Date : 2021-12-01 DOI: 10.1016/j.ijpam.2020.10.002
Abdullah Al Shamrani FRCPCH, Ayshah AlShammari MD, Halima AlAlkami MD, Jawaher AlShanwani MD, Adel S. Alharbi FCCP
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