BANTAO Journal最新文献

{"title":"Kidney Transplantation Program in Montenegro","authors":"M. Ratković, N. Jukić, D. Radunović, V. Prelevic, Branka Gledović","doi":"10.1515/bj-2015-0015","DOIUrl":"https://doi.org/10.1515/bj-2015-0015","url":null,"abstract":"Abstract Introduction. There was no transplantation program in Montenegro until 2012. On the other hand, there were 93 patients with transplanted kidney. These transplantations were performed abroad; 15% in areas of black organ markets (India, Pakistan, Russian Federation). Beside the ethical problems, these transplantations carried a high risk of complications. Methods. Our health system had to ensure solution for patients with terminal organ failure. Preparation of all neccessary conditions for the beginning of transplantation program in Montenegro started in 2006 with different activities including public, legal, medical, educational and international cooperation aspects. Results. The first kidney transplantation from living donor in Montenegro was preformed on September 25th, 2012. In the period from 2012 until now 23 kidney transplantations from living related donor were performed and one kidney transplantation from deceased donor in the Clinical Center of Montenegro. In the a two year-follow-up period, all patients to whom kidney transplantation was performed are in a good condition and without serious complications in posttransplant period. Conclusion. Development of the transplantation program allowed controlled transplantation and safety of patients. Our next steps are development of deceased organ donor transplantation and achievement of higher rate of deceased donor organ transplantation and individualization of immunosuppressive therapy.","PeriodicalId":365549,"journal":{"name":"BANTAO Journal","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131284113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Interdialytic Weight Gain (IDWG) on Nutritional Parameters, Cardiovascular Risk Factors and Quality of Life in Hemodialysis Patients","authors":"A. Kahraman, H. Akdam, A. Alp, M. Huyut, C. Akgullu, Tuba Balaban, Fadime Dinleyen, Aynur Topcu, Husniye Gelmez, N. Atakan, H. Akar, Y. Yeniçerioğlu","doi":"10.1515/bj-2015-0006","DOIUrl":"https://doi.org/10.1515/bj-2015-0006","url":null,"abstract":"Abstract Introduction. The amount of interdialytic weight gain (IDWG) considering body weight is of great importance in hemodialysis patients. In general practice, patients are asked to get standard weight between two hemodialysis sessions. However, it should be individualized considering patient’s weight. We aimed to determine the association between the IDWG and the nutritional parameters, cardiovascular risk factors, and quality of life. Methods. Thrity-two patients receiving hemodialysis at least for one year were enrolled into the study. Patients were monitored for 12 consecutive hemodialysis sessions; and the arithmetic mean of IDWG was calculated. IDWG% was calculated in accordance with patients’ dry weight. Data of patients with IDWG<3% (Group I) and IDWG≥3 (Group II) were compared. Sociodemographic variables, laboratory, anthropometric measurements, blood pressure, left ventricular mass index, Subjective Global Assessment Scale and SF-36 Quality of Life Scale were applied to evaluate the patients. Results. 59.4% (n=19) and 40.6% (n=13) of patients were included in Group I and Group II, respectively. In Group II, albumin (p=0.02), potassium (p=0.02), phosphorus (p=0.04), nPCR (p=0.03), physical function (p=0.04), role limitations caused by physical problems (p=0.04), general health (p=0.03), physical quality of life (p=0.04) scores were significantly higher. A significant correlation was detected between IDWG and physical and mental quality of life, total score SF-36, albumin, total protein and the potassium values. Conclusions. Patients with an IDWG ≥ 3% have better nutritional parameters and quality of life scales. The limiting of IDWG to 1-2 kg, ingoring patient weight may give rise to malnutrition and a reduced quality of life.","PeriodicalId":365549,"journal":{"name":"BANTAO Journal","volume":"90 ","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133971356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association Between Hypertension and Residual Renal Function in Hemodialysis Patients","authors":"S. Ajanović, H. Resić, F. Masnic, A. Ćorić, A. Bečiragić, N. Prohić, A. Džubur, M. Tomić","doi":"10.1515/bj-2015-0016","DOIUrl":"https://doi.org/10.1515/bj-2015-0016","url":null,"abstract":"Abstract Introduction. Cardiovascular diseases are the leading cause of death in hemodialysis patients. The decline of residual renal function increases the prevalence and severity of risk factors of cardiovascular morbidity and mortality in these patients. Hypertension is common in dialysis patients and represents an important independent factor of survival in these patients. Methods. The study included 77 patients who are on chronic HD for longer than 3 months. Depending on the measured residual diuresis patients were divided into two groups. The study group consisted of patients with residual diuresis >250 ml/day, while patients from control group had residual diuresis <250 ml/day. All patients had their blood pressure measured before 10 consecutive hemodialysis treatments. Collected data were statistically analyzed using SPSS 16.0. Results. The study included 77 hemodialysis patients, mean age of 56.56±14.6 years and mean duration of hemodialysis treatment of 24.0 months. Of the total number of patients, 39(50.6%) had preserved residual renal function. Hypertension was more common in the group of patients who did not have preserved residual renal function (68.4% vs 25.6%). There was statistically significant negative linear correlation between the volume of residual urine output and the residual clearance of urea and values of systolic blood pressure [(rho=−0.388; p<0.0001); (rho=−0.392; p<0.0005)], values of mean arterial pressure [(rho =−0.272; p<0.05); (rho=−0.261; p=0.023; p<0.05)] and values of pulse pressure in hemodialysis patients [(rho =−0.387; p<0.001); (rho=−0.400; p<0.0005)]. Conclusions. Residual renal function plays an important role in controlling blood pressure in patients on hemodialysis. More attention should be directed to preserve residual renal function, and after the start of hemodialysis by avoiding intensive ultrafiltration with optimal antihypertensive therapy.","PeriodicalId":365549,"journal":{"name":"BANTAO Journal","volume":"221 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116414425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Contrast Induced Nephropathy in Patients with Acute Coronary Syndrome","authors":"Mehmet Can Uğur, F. Ekinci, U. Soyaltin, H. Akar","doi":"10.1515/bj-2015-0003","DOIUrl":"https://doi.org/10.1515/bj-2015-0003","url":null,"abstract":"Abstract Introduction. Contrast-induced nephropathy (CIN) is associated with increased morbidity and mortality after percutaneous coronary intervention (PCI). On the other hand, CIN is a serious complication in patients with diabetes or renal impairment undergoing percutaneous coronary intervention (PCI). CIN after PCI may be associated with prolonged hospitalization, increased rates of kidney injury, and short- and long-term mortality. Factors that have been associated with CIN include: diabetes mellitus, congestive heart failure, recent acute myfocardial infarction, cardiogenic shock, and pre-existing renal impairment. In this study, we investigated contrast nephropathy development after coronary angiography (CAG) in patients presenting with acute coronary syndrome, who were hospitalized initially in the Coronary Care Unit and subsequenttly referred to the Internal Medicine Clinic in a tertiary care hospital. Methods. We’ve analyzed 335 patients’ records retrospectively in 1 year that were followed-up with acute coronary syndrome (ACS) in the Coronary Care Unit (CCU) and transferred to the Internal Medicine Clinic (IMC). The following parameters were evaluated: age, gender, chronic disease and drug history, biochemical values evaluated before hospitalization to CCU, ejection fraction (EF) and left atrium diameter (LA), with or without previous CAG; values of serum creatinine (sCr) levels before CAG and after 48 hours. Values of p <0.05 were considered to be significant. Results. 126 of 335 patients were female and 209 were male. The average age of patients was 64.2 years. 122 patients used angiotensin converting enzyme inhibitor (ACEI), 54 patients used furosemide. CIN development rate of CAG patients was 22.8% (n=54). There was no significant relationship with age, gender and chronic disease history in CIN patients. When laboratory findings were compared, there was no significant relationship except for potassium value before CAG. However, potassium values were significantly higher in CIN patients (p=0.001). When drug usage of patients was compared, 48.1% (n=26) of CIN patients used ACEI and there was a significant relationship between ACEI use and CIN development (p=0.026). Conclusions. CIN development rate was 22.8% and it was relatively high when compared with literature data. Awareness about contrast nephropathy develepment risk and assessment of risk factors before the procedure should be increased in our Center.","PeriodicalId":365549,"journal":{"name":"BANTAO Journal","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115450622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Idiopatic Systemic Capillary Leak Syndrome Treated Successfully with High-Dose Intravenous Immunoglobulins","authors":"F. Ekinci, U. Soyaltin, H. Akar, Mehmet Can Uğur, Ercan Ersoy, A. Komaç, T. D. Yıldırım","doi":"10.1515/bj-2015-0019","DOIUrl":"https://doi.org/10.1515/bj-2015-0019","url":null,"abstract":"Abstract Idiopathic systemic capillary leak syndrome (ISCLS) is characterized by a triad of hypotension, hemoconcentration and hypoalbuminemia due to a shift of intravascular fluid and albumin to the extravascular area. We describe a hypovolemic patient with hemoconcentration and hypoalbuminemia who was successfully treated with high-dose intravenous immunoglobulins (IVIG). The purpose of this case report is to discuss the clinical management of idiopathic systemic capillary leak syndrome on the background of relevant literature review.","PeriodicalId":365549,"journal":{"name":"BANTAO Journal","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122858658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Rare Case of Peritonitis: Streptococcus Salivarius","authors":"E. Cebeci, N. Samanci, M. Gursu, S. Ozturk, F. Pehlivanoğlu, A. Şumnu, S. Karadağ, R. Kazancioglu","doi":"10.1515/bj-2015-0021","DOIUrl":"https://doi.org/10.1515/bj-2015-0021","url":null,"abstract":"Abstract Streptococcus salivarius is a Gram-positive bacteria that may cause infections like endocarditis and meningitis. However, it has not been reported as a causative agent of peritonitis in peritoneal dialysis patients. In this paper we present a rare case of peritonitis with Streptococcus salivarius admitted to our Clinic with abdominal pain, who had been on peritoneal dialysis treatment for 19 months. Streptococus salivarius was cultured from the effluent, sensitive to ampicillin and penicillin G. Patient was discharged completely cured. Peritonitis is the most important clinical issue that occurs in patients treated with peritoneal dialysis, and every effort should be invested to determine the causative agent while even rare bacteria as Streptococcus salivarius may be found.","PeriodicalId":365549,"journal":{"name":"BANTAO Journal","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130215774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation of Residual Diuresis with MIS Score and Nutritional Status in Peritoneal Dialysis Patients: A Croatian Nationwide Study","authors":"N. Bašić-Jukić, B. Vujičić, J. Radić, D. Klarić, Željka Grdan, G. Radulović, K. Jurić, K. Altabas, M. Jakić, Valentina Ćorić-Martinović, Ivana Kovačević-Vojtušek, M. Gulin, N. Janković, D. Ljutić, S. Rački","doi":"10.1515/bj-2015-0014","DOIUrl":"https://doi.org/10.1515/bj-2015-0014","url":null,"abstract":"Abstract Introduction. Residual diuresis (RD) is an important predictor of mortality and cardiovascular (CV) deaths in peritoneal dialysis (PD) patients, and contributes more to overall survival compared to PD clearance. In this study we investigated the correlation between RD and CV outcomes in PD patients. Methods. A total of 190 PD patients from 13 dialysis centers, a national representation, were included in this analysis. Biomarkers of anemia, nutritional status [malnutrition inflammation score (MIS), subjective global assessment (SGA), serum albumin, anthropometric measurements including body mass index (BMI)], dialysis dose (Kt/V) and laboratory measurements were determined. RD was estimated using the volume of daily urine. Results. There were 78(41.05 %) females and 112 (58.95 %) males; aged 57.35±14.41 years, on PD for 24.96±24.43 months. Fifty-six patients had diabetes type II (44 as primary kidney disease). The mean RD was 1170±673.6 ml (range 0-3000 mL). Statistically significant correlations between RD and BMI, hip circumference, time on PD, Kt/V, MIS, SGA, erythrocytes (E), Hemoglobin (Hb), PTH, and serum albumin were observed. Conclusions. We demonstrated a significant correlation between RD and MIS score, SGA, anthropometry and albumin. Every effort should be invested to maintain RD for as long as possible to achieve optimal treatment results and to decrease CV mortality in PD population.","PeriodicalId":365549,"journal":{"name":"BANTAO Journal","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130979865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Central Nervous System Involvement under Intensive Immunosuppressive Treatment in a Patient Diagnosed with Granulomatosis Polyangiitis: A Case Report","authors":"Z. Çelebi, O. Kucuksahin, E. Peker, S. Kutlay, G. Nergizoğlu, K. Ateş, O. Karatan","doi":"10.1515/bj-2015-0011","DOIUrl":"https://doi.org/10.1515/bj-2015-0011","url":null,"abstract":"Abstract Granulomatosis polyangiitis (Wegener's granulomatosis) is an ANCA-associated necrotising vasculitis. The disease involves upper respiratory tract, the lungs and kidneys but central nervous system (CNS) involvement is 1-5%. A 40-year-old male patient was admitted to the hospital with joint pain, rash, aphthous lesions. The skin biopsy from the lesion showed leukocytoclastic vasculitis. The patient had c-ANCA positive and was diagnosed granulomatosis polyangiitis. He was treated with a pulse steroid and cyclophosphamide. Before the 5th session of therapy, the patient developed hemoptysis and hematuria. Thorax CT (computarized tomography) showed a diffuse alveolar hemorrhage and hence plasmapheresis and IVIG (intravenous immunoglobulin) were added to the treatment. Two days after IVIG, the patient developed globe vesical, headache and respiratory arrest. MR (magnetic resonance) showed CNS involvement. The patient was treated with a pulse steroid, but did not respond to therapy and died after 5 months since establishing the diagnosis. More studies are needed to identify effective treatment and course of disease for patients with central nervous system involvement.","PeriodicalId":365549,"journal":{"name":"BANTAO Journal","volume":"212 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115775092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Initial PET Status on Clinical Course in Peritoneal Dialysis Patients","authors":"T. Şakacı, Y. Koc, T. Basturk, M. Sevinc, E. Ahbap, A. Si̇nangi̇l, E. Kara, Z. Ucar, C. Akgol, A. Kayalar, F. Çağlayan, T. Şahutoğlu, A. Unsal","doi":"10.1515/bj-2015-0004","DOIUrl":"https://doi.org/10.1515/bj-2015-0004","url":null,"abstract":"Abstract Introduction. To investigate the effect on mortality of initial peritoneal equilibration test (PET) in PD patients (pts). Methods. We included patients who initiated therapy between 2001-2014. Patients underwent initial PET in the first three months. They were divided into four groups according to the initial PET (high, high-average, lowaverage, low transport). Sociodemographic data, clinical courses and infectious complications between groups were compared, and the reasons for PD withdrawal were obtained. Technique survival analyses of patients were done. Results. In a total of 367 pts were PD was started, 104 pts were excluded. Data of the remaining 263 patients were evaluated. Thirty-seven pts (23F, mean age 44.6±16.5 years, mean follow-up 30.5±20.8 months) had high transport, 90 pts (49F, mean age 41.5±16 years, mean followup 42.6±27.7 months) had high-average transport, 91 pts (55F, mean age 44.5±14.9 years, mean follow-up 50±29.2 months) had low-average transport and 45 pts (17F, mean age 43.5±14 years, mean follow-up (63.4±34.5 months) had low transport. There was no difference between groups in terms of age, gender, body mass index, initial daily urine and ultrafiltration volume, initial albumin levels, presence of diabetes mellitus (p>0.05). Peritonitis and catheter exit-site/tunnel infection attacks were higher in patients with high transport (p=0.01 and 0.008, respectively). There was a difference between groups with respect to the last status of patients (p< 0.009). The major causes of deaths were peritonitis and/or sepsis and cardiovascular causes in all patients. The mortality and technique survival rate was found higher in patients with high transport (log rank: 0.004 and 0.027, respectively). Age (OR:1.045, p<0.001), initial albumin (OR: 0.482, p= 0.007), daily urine volume (OR: 1.045, p<0.001) and presence of catheter exit-site/tunnel infection (OR: 0.249, p<0.001) were found to predict patient survival. Only presence of catheter exit-site/tunnel infection (OR: 0.452, p=0.013) were found to predict patient survival. Conclusions. Initial PET has effects on PD patient survival; patients with high transport have the worst survival and frequent infectious complications.","PeriodicalId":365549,"journal":{"name":"BANTAO Journal","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131722361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is there any Gender Difference in the Association between Obesity, Chronic Kidney Disease and Anemia","authors":"K. Atanassova, J. Masin‐Spasovska, G. Spasovski, E. Paskalev","doi":"10.1515/bj-2015-0017","DOIUrl":"https://doi.org/10.1515/bj-2015-0017","url":null,"abstract":"Abstract Introduction. Nowadays, obesity has emerged as one of the most independent risk factors for chronic kidney disease (CKD) in both economically developed and undeveloped countries. The number of patients requiring dialysis as a consequence of obesity-related renal diseases, such as diabetes mellitus and hypertension, is increasing worldwide. Moreover, obesity has been shown to favorize the risk of cardiovascular diseases (CVD) with premature death due to CKD and/or end-stage renal disease (ESRD). The aim of the study was to investigate the association between obesity [e.g. body mass index (BMI)], kidney function [e.g. glomerular filtration rate (GFR)] and renal anemia in CKD patients. Methods. Retrospectively, data from the register of 315 pre-dialysis patients with different stages of CKD not on erythropoiesis stimulation agents (ESAs) during the period between 1 Jan 2013-30 June 2013 were used to assess the association between the degree of CKD impairment with the degree of obesity and anemia. The stage and/or progression of CKD was calculated by GFR, while the degree of obesity by the body mass index (BMI). CKD was defined as a glomerular filtration rate (GFR) <60 mL/min per 1.73 m2. Data analysis was performed by means of the simple Microsoft excel program. Results. Within the study population of 315 CKD patients, 123 were males with mean age of 63.4±1.33 years and 192 females of 57.3±1.2 years. The GFR reduced with the increased BMI in both genders, and majority of patients (n=243) were in CKD stage 3, with a mean GFR of 44.5 ml/min/1.73 m2. The BMI values in female patients with first and second degree of obesity negatively correlated with GFR (r=−0.46, p<0.05). Only female patients with second degree of obesity (BMI of 35-39.9 kg/m2) had a positive correlation between the decreased renal function and reduced Hb levels. Conclusions. Our study provided an unconditional evidence not only for the presence of an association between the degree of obesity (BMI) and the degree of renal function impairment (GFR), but also an association between the higher BMI and the higher degree of kidney anemia seen in women with second degree of obesity. Further larger scale trials and interventional studies are required to see the effect of body weight reduction on renal function and especially anemia.","PeriodicalId":365549,"journal":{"name":"BANTAO Journal","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125218595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}