Mathias Froidevaux, Sophie Vandenberghe-Dürr, Amélie Borgeat, Julien Maillard
{"title":"Safe Administration of Octenidine in a Surgical Patient With Documented Severe Chlorhexidine Anaphylaxis: A Case Report and Review of the Current Evidence.","authors":"Mathias Froidevaux, Sophie Vandenberghe-Dürr, Amélie Borgeat, Julien Maillard","doi":"10.1155/cria/5754614","DOIUrl":"10.1155/cria/5754614","url":null,"abstract":"<p><p>Chlorhexidine is one of the most widely used antiseptics worldwide. Owing to its extensive use, reports of chlorhexidine allergic reactions are increasing. In cases of severe chlorhexidine anaphylaxis, the potential for cross-reactivity with other antiseptics poses a significant challenge when considering an alternative. We present a case of successful use of octenidine in a patient with confirmed chlorhexidine anaphylaxis, illustrating the low risk of systematic cross-sensitivity, as already suggested by ex vivo studies, and raising the possibility of its potential use as a reliable alternative.</p>","PeriodicalId":36504,"journal":{"name":"Case Reports in Anesthesiology","volume":"2025 ","pages":"5754614"},"PeriodicalIF":0.0,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12479366/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145207841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Charcot-Marie-Tooth Disease With Persistent Perioperative Hypotension due to Autonomic Dysfunction: A Case Report.","authors":"Keevan Singh, Anna-Maria Lawrence","doi":"10.1155/cria/9639101","DOIUrl":"10.1155/cria/9639101","url":null,"abstract":"<p><p>Charcot-Marie-Tooth (CMT) is a hereditary neuromuscular syndrome associated with peripheral neuropathy. We describe a case of long-standing CMT disease who underwent general anesthesia for a total knee replacement and developed significant perioperative hypotension. Clinical assessment revealed vasoplegia due to underlying autonomic dysfunction as the most likely cause. Further review also revealed a similar episode of intraoperative hypotension during a previous anesthetic. After failure of conservative strategies, the patient was started on a vasopressor infusion. However, hypotension persisted in the early postoperative period. This case serves to highlight the significance of autonomic dysfunction in CMT patients which can cause perioperative hypotension, a finding that has been rarely reported in the literature. We also discuss current diagnostic modalities that may be useful in managing cases of autonomic dysfunction that may present with hypotension.</p>","PeriodicalId":36504,"journal":{"name":"Case Reports in Anesthesiology","volume":"2025 ","pages":"9639101"},"PeriodicalIF":0.0,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12479046/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145201189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shahbaz Saad, Federico Ciardi, Nathan Praschan, Brittani Bungart, Michael Fettiplace
{"title":"Propofol Exposure Precipitating a Functional Movement Disorder: A Case Report.","authors":"Shahbaz Saad, Federico Ciardi, Nathan Praschan, Brittani Bungart, Michael Fettiplace","doi":"10.1155/cria/8850185","DOIUrl":"10.1155/cria/8850185","url":null,"abstract":"<p><p>Drug-induced movement disorders are a rare but distressing complication of many anesthetic agents. When such reactions occur, it is difficult to identify a causative agent. We report a case of recurrent ataxia, dysarthria, chorea, and tremors following multiple anesthetics in a 32-year-old patient with a history of significant postoperative nausea and vomiting. Over the course of four anesthetics, the exclusion of propofol, along with collaborative planning via a biopsychosocial approach, prevented the onset of a functional movement disorder. Therefore, for the first time, we highlight a case of functional movement disorder precipitated by intraoperative propofol.</p>","PeriodicalId":36504,"journal":{"name":"Case Reports in Anesthesiology","volume":"2025 ","pages":"8850185"},"PeriodicalIF":0.0,"publicationDate":"2025-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12416804/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145201207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Using Remimazolam to Generate Hemodynamically Stable Burst Suppression: A Case Report and Literature Review.","authors":"Chin Fung Kelvin Kan, Jacob E Pollard","doi":"10.1155/cria/7512576","DOIUrl":"10.1155/cria/7512576","url":null,"abstract":"<p><p>Remimazolam is a short-acting benzodiazepine that was approved by the United States Food and Drug Administration (FDA) in 2020 for the induction and maintenance of procedural sedation in adults undergoing procedures lasting 30 min or less. Given its recent introduction, the use of remimazolam for general anesthesia and monitored anesthesia care (MAC) remains an area of ongoing investigation. In this report, we present the first documented case demonstrating that remimazolam can achieve hemodynamic stable burst suppression in a critically ill patient undergoing emergent craniectomy and aneurysm clipping. Additionally, this manuscript reviews the reported off-label applications of remimazolam in both the operating room and the intensive care unit (ICU) settings.</p>","PeriodicalId":36504,"journal":{"name":"Case Reports in Anesthesiology","volume":"2025 ","pages":"7512576"},"PeriodicalIF":0.0,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12328058/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144795788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alexander B Froyshteter, Jillian A Dibiase, Catherine M Seager, Alina Lazar
{"title":"Infant Spinal Anesthesia for Urologic Surgery in a Patient With Epidermolysis Bullosa.","authors":"Alexander B Froyshteter, Jillian A Dibiase, Catherine M Seager, Alina Lazar","doi":"10.1155/cria/2537488","DOIUrl":"10.1155/cria/2537488","url":null,"abstract":"<p><p>Infant spinal anesthesia presents a viable alternative to general anesthesia for short procedures below the umbilicus. This technique eliminates the need for airway instrumentation while preserving hemodynamic and respiratory parameters. Epidermolysis bullosa is a rare inherited genetic disorder marked by mucocutaneous fragility, erosions, ulcerations, and blister formation. Anesthesia management for patients with epidermolysis bullosa necessitates meticulous planning to minimize shearing stress on the skin and mucosa. This case report details the application of spinal anesthesia for an infant with epidermolysis bullosa for urologic surgery, highlighting special considerations for neuraxial block placement in this vulnerable population.</p>","PeriodicalId":36504,"journal":{"name":"Case Reports in Anesthesiology","volume":"2025 ","pages":"2537488"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12255489/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144627352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Erector Spinae Plane Block in Open Appendectomy: A Case Series.","authors":"Jassim Rauf, Mohammad Mohsin A M Haji","doi":"10.1155/cria/3705137","DOIUrl":"10.1155/cria/3705137","url":null,"abstract":"<p><p><b>Background:</b> Open appendicectomy is a painful procedure requiring multimodal analgesia. Various fascial planes have been used successfully in the past as part of this multimodal analgesia like TAP block, quadratus lumborum block, and even local infiltration. All of these analgesic regimes have been shown to reduce intra- and postoperative opioid consumption. In this case series, we elaborate on the effects of ESPB on the consumption of opioids in the intra- and postoperative periods of two patients undergoing open appendicectomy. <b>Case Series:</b> Two American Society of Anesthesiologists (ASA) Emergency (1E) patients scheduled to undergo open appendicectomy were consented to receive ESPB after receiving GA. The block was performed at the transverse process at T12 level, on the right side with 30 mLs of 0.25% levobupivacaine. One patient received intra-op IV paracetamol and ketorolac, while the other patient did not receive paracetamol as he already received it in the ward and ketorolac was withheld due to high creatinine. The surgeries went uneventful. Both patients reported 0 NRS pain score in PACU. One of the patients recorded 0 NRS pain score till discharge, and the other reported an NRS score of 5/10 at 19 h 30 min. Both were discharged from the hospital after 24 h. <b>Conclusion:</b> ESPB has a potential opioid sparing effect and can provide a total morphine free analgesia both in the intra- and postoperative period in the setting of an open appendicectomy.</p>","PeriodicalId":36504,"journal":{"name":"Case Reports in Anesthesiology","volume":"2025 ","pages":"3705137"},"PeriodicalIF":0.0,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12221555/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144555222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Case of Intraoperative Reproducible Transient Bradycardia During Total Hip Arthroplasty: Direct Activation of Parasympathetic Vagal Afferents From Bone.","authors":"Yifan Li, Joseph Moskal, Maxine Lee","doi":"10.1155/cria/5583839","DOIUrl":"10.1155/cria/5583839","url":null,"abstract":"<p><p>The Gallagher-Wilkinson reflex was first reported by Gallagher and Wilkinson in 2001, describing intraoperative transient and reproducible bradycardia and/or asystole during intramedullary reaming in patients undergoing total knee replacement. The reflex has been originally thought to result from an indirect mechanism: the elevated intramedullary pressure transmits to intrapelvic and intra-abdominal viscera, indirectly causing a vagally mediated reflex bradycardia. Other case reports have documented this reflex and discounted potential physiologic causes such as microemboli or primary cardiac arrhythmia. Several preclinical and clinical studies have demonstrated how the parasympathetic innervation of bone modulates bone remodeling. This paper presents a case of a patient who underwent a total hip replacement, experiencing intraoperative transient and reproducible bradycardia. We postulate a direct mechanism for the Gallagher-Wilkinson reflex: increased pressure from intramedullary reaming directly activates the parasympathetic nervous system in the bone axis leading to vagally-mediated bradycardia. This case offers an alternative explanation for the Gallagher-Wilkinson reflex and emphasizes the important need for additional research to better understand parasympathetic innervation in the bone axis.</p>","PeriodicalId":36504,"journal":{"name":"Case Reports in Anesthesiology","volume":"2025 ","pages":"5583839"},"PeriodicalIF":0.0,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12208748/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144530073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tara L Kelly, William Barrett, Amanda Bunnell, Toby B Steinberg, Christopher Wolla
{"title":"Timing of Epidural Placement After an Epidural Blood Patch.","authors":"Tara L Kelly, William Barrett, Amanda Bunnell, Toby B Steinberg, Christopher Wolla","doi":"10.1155/cria/1692478","DOIUrl":"10.1155/cria/1692478","url":null,"abstract":"<p><p>Epidural placement is a mainstay in the pain management of patients undergoing brachytherapy treatment of cervical cancer. A significant number of patients undergo multiple treatment cycles over the course of several weeks, necessitating repeated neuraxial catheter placements. This increases the risk of complications, including postdural puncture headaches, which may require further neuraxial instrumentation for the administration of an epidural blood patch. We present the case of a patient who received an epidural blood patch for postdural puncture headache in the middle of her brachytherapy treatment series. There is limited literature addressing the optimal timing for subsequent epidural catheter placement after an epidural blood patch.</p>","PeriodicalId":36504,"journal":{"name":"Case Reports in Anesthesiology","volume":"2025 ","pages":"1692478"},"PeriodicalIF":0.0,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12170071/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144310459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gabrielle A White-Dzuro, Xiaodong Bao, Francis McGovern, Robert A Peterfreund
{"title":"Should Spinal Anesthesia Be Used for Spine Surgery: A Case Report.","authors":"Gabrielle A White-Dzuro, Xiaodong Bao, Francis McGovern, Robert A Peterfreund","doi":"10.1155/cria/7810025","DOIUrl":"https://doi.org/10.1155/cria/7810025","url":null,"abstract":"<p><p>A patient with lumbar spine stenosis presented for lumbar spine decompression, clearly stating a preference for spinal anesthesia (SA) over general anesthesia (GA). Surgery was performed under uneventful SA without sedation. The patient recovered from surgery quickly and without incident, requiring no postoperative opioid analgesia. What data support administering SA for lumbar spine surgery? A literature search found nine recently published reviews favoring SA over GA. These reviews cited many of the same, older, flawed, primary research reports. Although choosing SA was reasonable, our literature analysis suggests blind reliance on summary conclusions of reviews and meta-analyses may be misleading.</p>","PeriodicalId":36504,"journal":{"name":"Case Reports in Anesthesiology","volume":"2025 ","pages":"7810025"},"PeriodicalIF":0.0,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12052442/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144051945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Patrick N Wiseman, Molly Featherstone, Noreen Dowd, Aislinn Sherwin
{"title":"Peripheral Regional Anesthesia for Awake Emergency Upper Limb Trauma Surgery in an Adult Patient With Fontan Physiology.","authors":"Patrick N Wiseman, Molly Featherstone, Noreen Dowd, Aislinn Sherwin","doi":"10.1155/cria/9525591","DOIUrl":"https://doi.org/10.1155/cria/9525591","url":null,"abstract":"<p><p><b>Background:</b> The Fontan procedure is the principal technique used in the surgical palliation of a range of congenital heart defects involving a single functional ventricle. With improvements in surgical technique and medical management, patients with Fontan physiology are surviving longer and a growing number are now presenting for noncardiac surgery in adulthood. The Fontan physiology provides a unique challenge for anaesthesiologists managing their perioperative care. This case report explores this challenge further and emphasises the benefits which regional anaesthesia can provide in the management of these complex patients. <b>Case Presentation:</b> We report the successful use of supraclavicular brachial plexus and intercostobrachial nerve blockade for awake surgery in a 27-year-old patient who had previously undergone a Fontan procedure at 5 years of age and now presented for emergency fixation of complex fractures of his radius, ulna and olecranon following a fall from his electric bicycle. <b>Conclusions:</b> This case report and ensuing discussion highlight the benefits which regional anaesthesia can provide for adult patients with complex cardiac physiology, including Fontan circulation, undergoing noncardiac surgery when compared to general anaesthesia.</p>","PeriodicalId":36504,"journal":{"name":"Case Reports in Anesthesiology","volume":"2025 ","pages":"9525591"},"PeriodicalIF":0.0,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12003033/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144040269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}